AF-O75460-K1

ERN1 (Serine/threonine-protein kinase/endoribonuclease IRE1)
Group: OTHER
Uniprot: ERN1_HUMAN
Organism: Homo sapiens
Domain boundary: 569 - 832
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 561 - 840 0
Representative sequence - Chain A
570 580 590 600
TSVVIVGKIS FCPKDVLGHG AEGTIVYRGM FDNRDVAVKR
610 620 630 640
ILPECFSFAD REVQLLRESD EHPNVIRYFC TEKDRQFQYI
650 660 670 680
AIELCAATLQ EYVEQKDFAH LGLEPITLLQ QTTSGLAHLH
690 700 710 720
SLNIVHRDLK PHNILISMPN AHGKIKAMIS DFGLCKKLAV
730 740 750 760
GRHSFSRRSG VPGTEGWIAP EMLSEDCKEN PTYTVDIFSA
770 780 790 800
GCVFYYVISE GSHPFGKSLQ RQANILLGAC SLDCLHPEKH
810 820 830 840
EDVIARELIE KMIAMDPQKR PSAKHVLKHP FFWSLEKQLQ


Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None