Protein kinases in complex with H8H (Saracatinib)

Total number of genes: 4
Total number of chains: 8
Spatial Dihedral Chains Representative
DFGin BLAminus 3 5VD3A
DFGin ABAminus 4 6ZGCC
DFGin BLBplus 1 2H8HA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
OTHER PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCXA 2.7 Active DFGin BLAminus in-in in-in H8H Type1
OTHER PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VD3A 1.8 Active DFGin BLAminus in-in in-in H8H Type1
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 4QMXA 1.882 Active DFGin BLAminus in-in in-in H8H Type1
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6ZGCA 2.67 Inactive DFGin ABAminus in-out in-in H8H Type1
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6ZGCB 2.67 Inactive DFGin ABAminus in-out in-in H8H Type1
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6ZGCC 2.67 Inactive DFGin ABAminus in-none in-in H8H Type1
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6ZGCD 2.67 Inactive DFGin ABAminus in-out in-in H8H Type1
TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 2H8HA 2.2 Inactive DFGin BLBplus out-out out-out H8H Type1

Protein kinases in complex with H8H

Total number of genes: 4
Total number of chains: 8
Spatial Dihedral Chains Representative
DFGin BLAminus 3 5VD3A
DFGin ABAminus 4 6ZGCC
DFGin BLBplus 1 2H8HA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens OTHER PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCXA 2.7 Active DFGin BLAminus in-in in-in H8H Type1
Homo sapiens OTHER PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VD3A 1.8 Active DFGin BLAminus in-in in-in H8H Type1
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 4QMXA 1.882 Active DFGin BLAminus in-in in-in H8H Type1
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6ZGCA 2.67 Inactive DFGin ABAminus in-out in-in H8H Type1
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6ZGCB 2.67 Inactive DFGin ABAminus in-out in-in H8H Type1
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6ZGCC 2.67 Inactive DFGin ABAminus in-none in-in H8H Type1
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6ZGCD 2.67 Inactive DFGin ABAminus in-out in-in H8H Type1
Homo sapiens TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 2H8HA 2.2 Inactive DFGin BLBplus out-out out-out H8H Type1

Protein kinases in complex with H8H

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type