HASPIN (Serine/threonine-protein kinase haspin)

Group: OTHER
Uniprot: HASP_HUMAN
Domain boundary: 484 - 797


Total number of chains: 32
Spatial Dihedral Chains Representative
DFGin BLAminus 32 AF-Q8TF76-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q8TF76-K1A -1.0 Active DFGin BLAminus in-in in-none No_ligand No_ligand 476 - 798 None None 0
2WB8A 2.15 Active DFGin BLAminus in-in in-none No_ligand No_ligand 447 - 798 None None 0
5HTBA 1.7 Active DFGin BLAminus in-in in-none No_ligand No_ligand 471 - 798 None None 0
5HTCA 1.5 Active DFGin BLAminus in-in in-none No_ligand No_ligand 471 - 798 None None 0
6G39A 1.45 Active DFGin BLAminus in-in in-none 5ID Type1 471 - 798 F605Y None 0
2VUWA 1.8 Active DFGin BLAminus in-in in-none 5ID Type1 470 - 798 None None 0
3DLZA 1.85 Active DFGin BLAminus in-in in-none AMP Type1 470 - 798 None None 0
3E7VA 2.0 Active DFGin BLAminus in-in in-none DZO Type1 471 - 798 None None 0
3F2NA 1.8 Active DFGin BLAminus in-in in-none IZZ Type1 471 - 798 None None 0
3FMDA 2.0 Active DFGin BLAminus in-in in-none IQB Type1 470 - 798 None None 0
3IQ7A 2.0 Active DFGin BLAminus in-in in-none 5ID Type1 471 - 798 None None 0
4OUCA 1.9 Active DFGin BLAminus in-in in-none 5ID Type1 470 - 798 None None 0
4QTCA 1.4 Active DFGin BLAminus in-in in-none 38Z Type1 469 - 798 None None 0
6G34A 1.76 Active DFGin BLAminus in-in in-none 5ID Type1 472 - 798 None None 0
6G35A 1.55 Active DFGin BLAminus in-in in-none EKK Type1 465 - 798 None None 0
6G36A 1.46 Active DFGin BLAminus in-in in-none EKH Type1 465 - 798 None None 0
6G37A 1.48 Active DFGin BLAminus in-in in-none FTU Type1 472 - 798 None None 0
6G38A 1.47 Active DFGin BLAminus in-in in-none TBN Type1 472 - 798 None None 0
6Z57A 1.5 Active DFGin BLAminus in-in in-none Q8W Type1 470 - 798 None None 0
6Z58A 1.8 Active DFGin BLAminus in-in in-none Q9B Type1 470 - 798 None None 0
6Z59A 2.0 Active DFGin BLAminus in-in in-none Q98 Type1 471 - 798 None None 0
6Z5CA 1.75 Inactive DFGin BLAminus out-out in-none PQ5 Type1 470 - 798 None None 0
6Z5DA 1.75 Active DFGin BLAminus in-in in-none Q8Q Type1 470 - 798 None None 0
6Z5EA 1.5 Active DFGin BLAminus in-in in-none Q8K Type1 471 - 798 None None 0
7AVQA 1.65 Active DFGin BLAminus in-in in-none S1Z Type1 471 - 798 None None 0
7OPSA 2.38 Active DFGin BLAminus in-in in-none 07C Type1 471 - 798 None None 0
8RDKA 2.0 Active DFGin BLAminus in-in in-none YQT Type1 471 - 798 None None 0
7SQMA 1.78 Active DFGin BLAminus in-in in-none A5G Type1 453 - 798 None None 0
6G3AA 1.43 Inactive DFGin BLAminus in-out in-none 5ID Type1 471 - 798 F605T None 0
6Z56A 1.9 Inactive DFGin BLAminus out-out in-none Q7Q Type1.5_Back 470 - 798 None None 0
6Z5BA 1.9 Inactive DFGin BLAminus out-out in-none Q7Z Type1.5_Back 469 - 798 None None 0
6Z5AA 1.55 Inactive DFGin BLAminus out-out in-none Q8B Type1.5_Front 465 - 798 None None 0

HASPIN (Serine/threonine-protein kinase haspin)

Group: OTHER
Total number of chains: 32
Spatial Dihedral Chains Representative
DFGin BLAminus 32 AF-Q8TF76-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens HASP_HUMAN AF-Q8TF76-K1A -1.0 Active DFGin BLAminus in-in in-none No_ligand No_ligand 476 - 798 None None 0
Homo sapiens HASP_HUMAN 2WB8A 2.15 Active DFGin BLAminus in-in in-none No_ligand No_ligand 447 - 798 None None 0
Homo sapiens HASP_HUMAN 5HTBA 1.7 Active DFGin BLAminus in-in in-none No_ligand No_ligand 471 - 798 None None 0
Homo sapiens HASP_HUMAN 5HTCA 1.5 Active DFGin BLAminus in-in in-none No_ligand No_ligand 471 - 798 None None 0
Homo sapiens HASP_HUMAN 6G39A 1.45 Active DFGin BLAminus in-in in-none 5ID Type1 471 - 798 F605Y None 0
Homo sapiens HASP_HUMAN 2VUWA 1.8 Active DFGin BLAminus in-in in-none 5ID Type1 470 - 798 None None 0
Homo sapiens HASP_HUMAN 3DLZA 1.85 Active DFGin BLAminus in-in in-none AMP Type1 470 - 798 None None 0
Homo sapiens HASP_HUMAN 3E7VA 2.0 Active DFGin BLAminus in-in in-none DZO Type1 471 - 798 None None 0
Homo sapiens HASP_HUMAN 3F2NA 1.8 Active DFGin BLAminus in-in in-none IZZ Type1 471 - 798 None None 0
Homo sapiens HASP_HUMAN 3FMDA 2.0 Active DFGin BLAminus in-in in-none IQB Type1 470 - 798 None None 0
Homo sapiens HASP_HUMAN 3IQ7A 2.0 Active DFGin BLAminus in-in in-none 5ID Type1 471 - 798 None None 0
Homo sapiens HASP_HUMAN 4OUCA 1.9 Active DFGin BLAminus in-in in-none 5ID Type1 470 - 798 None None 0
Homo sapiens HASP_HUMAN 4QTCA 1.4 Active DFGin BLAminus in-in in-none 38Z Type1 469 - 798 None None 0
Homo sapiens HASP_HUMAN 6G34A 1.76 Active DFGin BLAminus in-in in-none 5ID Type1 472 - 798 None None 0
Homo sapiens HASP_HUMAN 6G35A 1.55 Active DFGin BLAminus in-in in-none EKK Type1 465 - 798 None None 0
Homo sapiens HASP_HUMAN 6G36A 1.46 Active DFGin BLAminus in-in in-none EKH Type1 465 - 798 None None 0
Homo sapiens HASP_HUMAN 6G37A 1.48 Active DFGin BLAminus in-in in-none FTU Type1 472 - 798 None None 0
Homo sapiens HASP_HUMAN 6G38A 1.47 Active DFGin BLAminus in-in in-none TBN Type1 472 - 798 None None 0
Homo sapiens HASP_HUMAN 6Z57A 1.5 Active DFGin BLAminus in-in in-none Q8W Type1 470 - 798 None None 0
Homo sapiens HASP_HUMAN 6Z58A 1.8 Active DFGin BLAminus in-in in-none Q9B Type1 470 - 798 None None 0
Homo sapiens HASP_HUMAN 6Z59A 2.0 Active DFGin BLAminus in-in in-none Q98 Type1 471 - 798 None None 0
Homo sapiens HASP_HUMAN 6Z5CA 1.75 Inactive DFGin BLAminus out-out in-none PQ5 Type1 470 - 798 None None 0
Homo sapiens HASP_HUMAN 6Z5DA 1.75 Active DFGin BLAminus in-in in-none Q8Q Type1 470 - 798 None None 0
Homo sapiens HASP_HUMAN 6Z5EA 1.5 Active DFGin BLAminus in-in in-none Q8K Type1 471 - 798 None None 0
Homo sapiens HASP_HUMAN 7AVQA 1.65 Active DFGin BLAminus in-in in-none S1Z Type1 471 - 798 None None 0
Homo sapiens HASP_HUMAN 7OPSA 2.38 Active DFGin BLAminus in-in in-none 07C Type1 471 - 798 None None 0
Homo sapiens HASP_HUMAN 8RDKA 2.0 Active DFGin BLAminus in-in in-none YQT Type1 471 - 798 None None 0
Homo sapiens HASP_HUMAN 7SQMA 1.78 Active DFGin BLAminus in-in in-none A5G Type1 453 - 798 None None 0
Homo sapiens HASP_HUMAN 6G3AA 1.43 Inactive DFGin BLAminus in-out in-none 5ID Type1 471 - 798 F605T None 0
Homo sapiens HASP_HUMAN 6Z56A 1.9 Inactive DFGin BLAminus out-out in-none Q7Q Type1.5_Back 470 - 798 None None 0
Homo sapiens HASP_HUMAN 6Z5BA 1.9 Inactive DFGin BLAminus out-out in-none Q7Z Type1.5_Back 469 - 798 None None 0
Homo sapiens HASP_HUMAN 6Z5AA 1.55 Inactive DFGin BLAminus out-out in-none Q8B Type1.5_Front 465 - 798 None None 0

HASPIN (Serine/threonine-protein kinase haspin)

No non-human structures known.