4Z7G

ERN1 (Serine/threonine-protein kinase/endoribonuclease IRE1)
Group: OTHER
Uniprot: ERN1_HUMAN
Organism: Homo sapiens
Domain boundary: 569 - 832
Resolu: 2.6

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None in-in none-in No_ligand No_ligand 562 - 963 19
B Inactive DFGin None in-in none-in No_ligand No_ligand 562 - 962 18
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       571        581        591        601 
SVVIVGKISF CPKDVLGHGA EGTIVYRGMF DNRDVAVKRI 
       611        621        631        641 
LPECFSFADR EVQLLRESDE HPNVIRYFCT EKDRQFQYIA 
       651        661        671        681 
IELCAATLQE YVEQKDFAHL GLEPITLLQQ TTSGLAHLHS 
       691        701        711        721 
LNIVHRDLKP HNILISMPNA HGKIKAMISD Fglckklavg 
       731        741        751        761 
rhsfsrrsgV PGTEGWIAPE MLSedckenP TYTVDIFSAG 
       771        781        791        801 
CVFYYVISEG SHPFGKSLQR QANILLGACS LDCLHPEKHE 
       811        821        831        841 
DVIARELIEK MIAMDPQKRP SAKHVLKHPF FWSLEKQLQF 
       851        861        871        881 
FQDVSDRIEK ESLDGPIVKQ LERGGRAVVK MDWRENITVP 
       891        901        911        921 
LQTDLRKFRT YKGGSVRDLL RAMRNKKHHY RELPAEVRET 
       931        941        951        961 
LGSLPDDFVC YFTSRFPHLL AHTYRAMELC SHERLFQPYY 
       971 
Fheppepqpp vtpdal
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None