Ligand

Protein kinases in complex with 3JW (Baricitinib)

Total number of genes: 2

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	4W9XA
DFGin	ABAminus	3	6WTOA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
OTHER	BMP2K	BMP2K_HUMAN	BMP-2-inducible protein kinase	4W9XA	2.14	Active	DFGin	BLAminus	in-in	in-in	3JW	Type1
TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	6VN8A	1.9	Inactive	DFGin	ABAminus	in-in	in-in	3JW	Type1
TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	6VN8B	1.9	Inactive	DFGin	ABAminus	in-in	in-in	3JW	Type1
TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	6WTOA	1.74	Inactive	DFGin	ABAminus	in-in	in-in	3JW	Type1

Protein kinases in complex with 3JW

Total number of genes: 2

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	4W9XA
DFGin	ABAminus	3	6WTOA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	OTHER	BMP2K	BMP2K_HUMAN	BMP-2-inducible protein kinase	4W9XA	2.14	Active	DFGin	BLAminus	in-in	in-in	3JW	Type1
Homo sapiens	TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	6VN8A	1.9	Inactive	DFGin	ABAminus	in-in	in-in	3JW	Type1
Homo sapiens	TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	6VN8B	1.9	Inactive	DFGin	ABAminus	in-in	in-in	3JW	Type1
Homo sapiens	TYR	JAK2	JAK2_HUMAN	Tyrosine-protein kinase JAK2	6WTOA	1.74	Inactive	DFGin	ABAminus	in-in	in-in	3JW	Type1

Protein kinases in complex with 3JW

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type