8EQE

EIF2AK3 (Eukaryotic translation initiation factor 2-alpha kinase 3)
Group: OTHER
Uniprot: E2AK3_HUMAN
Organism: Homo sapiens
Domain boundary: 593 - 1077
Resolu: 2.559

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
AAA Inactive DFGin None out-out out-none WQ2 Type1.5_Back 585 - 1080 26
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain AAA
       582        592        602        612 
gssswndikn sgYISRYLTD FEPIQCLGRG GfGVVFEAKN 
       622        632        642        652 
KVDDCNYAIK RIRLPNRELA REKVMREVKA LAKLEHPGIV 
       662        877        887        897 
RYFNAWLEAP PEKWqeklqp ssPKVYLYIQ MQLCRKENLK 
       907        917        927        937 
DWMNGRCTIE ERERSVCLHI FLQIAEAVEF LHSKGLMHRN 
       947        957        967        977 
LKPSNIFFTM DDVVKVGDFG LVTamdqdee eqtvltpmpa 
       987        997       1007       1017 
yarhtgqvgT KLYMSPEQIH GNSYSHKVDI FSLGLILFEL 
      1027       1037       1047       1057 
LYPFSTQMER VRTLTDVRNL KFPPLFTQKY PCEYVMVQDM 
      1067       1077       1087 
LSPSPMERPE AINIIENAVF EDLdfpgktv lrqrsrs
Lower-case residues are disordered in structure.
Mutations: D937N
Phosphorylation: None