2A19

EIF2AK2 (Interferon-induced, double-stranded RNA-activated protein kinase)
Group: OTHER
Uniprot: E2AK2_HUMAN
Organism: Homo sapiens
Domain boundary: 267 - 538
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
B Inactive DFGin ABAminus in-in in-out ANP Type1 258 - 541 0
C Inactive DFGin ABAminus in-in none-none ANP Type1 258 - 541 22
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain C
       264        274        284        294 
gaHTVDKRFG MDFKEIELIG SGGFGQVFKA KHRIDGKTYV 
       304        314        324        334 
IKRVKYNNEK AEREVKALAK LDHVNIVHYN GCWDGFDYDP 
       357        367        377        387 
ETSsknssrs KTKCLFIQME FCDKGTLeqw iekrrgekld 
       397        407        417        427 
kvLALELFEQ ITKGVDYIHS KKLINRDLKP SNIFLVDTKQ 
       437        447        457        467 
VKIGDFGLVt slkndgkrtr skgtlrymsp eqissqdyGK 
       477        487        497        507 
EVDLYALGLI LAELLhvcdt afetskfftd lrdGIISDIF 
       517        527        537        547 
DKKEKTLLQK LLSKKPEDRP NTSEILRTLT VWKKspekne 

rhta
Lower-case residues are disordered in structure.
Mutations: H412N,C551A
Phosphorylation: X446