5NTT

TTK (Dual specificity protein kinase TTK)
Group: OTHER
Uniprot: TTK_HUMAN
Organism: Homo sapiens
Domain boundary: 525 - 791
Resolu: 2.75

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus out-out out-out SVE Type1 519 - 797 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       520        530        540        550 
ENLYFQSMSV KGRIYSILKQ IGSGGSSKVF QVLNEKKQIY 
       560        570        580        590 
AIKYVNLEEA DNQTLDSYRN EIAYLNKLQQ HSDKIIRLYD 
       600        610        620        630 
YEITDQYIYM VMEYGNIDLN SWLKKKKSID PWERKSYWKN 
       640        650        660        670 
MLEAVHTIHQ HGIVHSDLKP ANFLIVDGML KLIDFGIANQ 
       680        690        700        710 
MQPDTTSVVK DSQVGTVNYM PPEAIKDMss srengkskSK 
       720        730        740        750 
ISPKSDVWSL GCILYYMTYG KTPFQQIINQ ISKLHAIIDP 
       760        770        780        790 
NHEIEFPDIP EKDLQDVLKC CLKRDPKQRI SIPELLAHPY 

VQIQTHP
Lower-case residues are disordered in structure.
Mutations: C604Y
Phosphorylation: X686