3SDJ

IRE1 (Serine/threonine-protein kinase/endoribonuclease IRE1)
Group: OTHER
Uniprot: IRE1_YEAST
Organism: Saccharomyces cerevisiae
Domain boundary: 674 - 980
Resolu: 3.65

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-in in-out APJ Type1 670 - 1115 0
B Inactive DFGin BLAminus in-in in-out APJ Type1 670 - 1115 0
C Inactive DFGin BLAminus in-in in-out APJ Type1 670 - 1115 0
D Inactive DFGin BLAminus in-in in-out APJ Type1 663 - 1115 0
E Inactive DFGin BLAminus in-in in-out APJ Type1 670 - 1115 0
F Inactive DFGin BLAminus in-in in-out APJ Type1 670 - 1115 0
G Inactive DFGin BLAminus in-in in-out APJ Type1 670 - 1115 0
H Inactive DFGin BLAminus in-in in-out APJ Type1 670 - 1115 0
I Inactive DFGin BLAminus in-in in-out APJ Type1 672 - 1115 0
J Inactive DFGin BLAminus in-in in-out APJ Type1 672 - 1115 0
K Inactive DFGin BLAminus in-in in-out APJ Type1 663 - 1115 0
L Inactive DFGin BLAminus in-in in-out APJ Type1 670 - 1115 0
M Inactive DFGin BLAminus in-in in-out APJ Type1 670 - 1115 0
N Inactive DFGin BLAminus in-in in-out APJ Type1 670 - 1115 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain N
       649        659        669        679 
pekkkrkrgs rggkkgrksr ianipnfeqs LKNLVVSEKI 
       689        699        709        719 
LGYGSSGTVV FQGSFQGRPV AVKRMLIDFC DIALMEIKLL 
       729        739        749        759 
TESDDHPNVI RYYCSETTDR FLYIALELCN LNLQDLVESK 
       769        779        789        799 
NVSDENLKLQ KEYNPISLLR QIASGVAHLH SLKIIHRDLK 
       809        819        829        839 
PQNILVSTSS RFTADQQTGA ENLRILISDF GLCKKLDSGQ 
       849        859        897        907 
SSFRTNLNNP SGTSGWRAPE LLEESTKRRL TRSIDIFSMG 
       917        927        937        947 
CVFYYILSKG KHPFGDKYSR ESNIIRGIFS LDEMKCLHDR 
       957        967        977        987 
SLIAEATDLI SQMIDHDPLK RPTAMKVLRH PLFWPKSKKL 
       997       1007       1017       1027 
EFLLKVSDRL EIENRDPPSA LLMKFDAGSD FVIPSGDWTV 
      1037       1047       1057       1067 
KFDKTFMDNL ERYRKYHSSK LMDLLRALRN KYHNFMDLPE 
      1077       1087       1097       1107 
DIAELMGPVP DGFYDYFTKR FPNLLIGVYM IVKENLSDDQ 

ILREFLYS
Lower-case residues are disordered in structure.
Mutations: H1061N
Phosphorylation: X840,X841,X844