6N3L

EIF2AK4 (eIF-2-alpha kinase GCN2)
Group: OTHER
Uniprot: E2AK4_HUMAN
Organism: Homo sapiens
Domain boundary: 590 - 1001
Resolu: 2.61

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout None in-in none-none KAV Type2 584 - 1002 0
B Inactive DFGout None in-in none-none KAV Type2 584 - 1002 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -        580        590        600 
mhhhhhhenl yfqggssetq rqfSRYFIEF EELQLLGKGA 
       610        620        630        640 
FGAVIKVQNK LDGCCYAVKR IPInpASRQF RRIKGEVTLL 
       650        783        793        803 
SRLHHENIVR YYNAWIEngc hesepsvtte avHYLYIQME 
       813        823        833        843 
YCEASTLRDT IDQGLYRDTV RLWRLFREIL DGLAYIHEKG 
       853        863        873        883 
MIHRNLKPVN IFLDSDDHVK IGDFglatdh lafsadskqd 
       893        903        913        923 
dqtgdliksd psghlagmvg AALYVSPEvq gstksaYNQK 
       933        943        953        963 
VDLFSLGIIF FEMSYHPMVT ASERIFVLNQ LRDPtspkFP 
       973        983        993       1003 
EDFddgeHAK QKSVISWLLN HDPAKRPTAT ELLKSELLPp 
      1013 
pqmeeselhe
Lower-case residues are disordered in structure.
Mutations: K807A,D848N,T899A,T904A
Phosphorylation: None