4C57

GAK (Cyclin-G-associated kinase)
Group: OTHER
Uniprot: GAK_HUMAN
Organism: Homo sapiens
Domain boundary: 40 - 315
Resolu: 2.55

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-out in-in FEF Type1 25 - 334 0
B Inactive DFGin ABAminus out-out in-in FEF Type1 27 - 334 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        21         31         41         51 
smpgslggas grdqsDFVGQ TVELGELRLR VRRVLAEGGF 
        61         71         81         91 
AFVYEAQDVG SGREYALKRL LSNEEEKNRA IIQEVCFMKK 
       101        111        121        131 
LSGHPNIVQF CSAASIGKEE SDTGQAEFLL LTELCKGQLV 
       141        151        161        171 
EFLKKMESRG PLSCDTVLKI FYQTCRAVQH MHRQKPPIIH 
       181        191        201        211 
RDLKVENLLL SNQGTIKLCD FGSATTISHY PDYSWSAQRR 
       221        231        241        251 
ALVEEEITRN TTPMYRTPEI IDLYSNFPIG EKQDIWALGC 
       261        271        281        291 
ILYLLCFRQH PFEDGAKLRI VNGKYSIPPH DTQYTVFHSL 
       301        311        321        331 
IRAMLQVNPE ERLSIAEVVH QLQEIAAARN VNPKSPITEL 
       341        351 
LEQnggygsa tlsrgppppv
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None