7BMK

ERN1 (Serine/threonine-protein kinase/endoribonuclease IRE1)
Group: OTHER
Uniprot: ERN1_HUMAN
Organism: Homo sapiens
Domain boundary: 569 - 832
Resolu: 1.85

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus out-out in-in U4N Type1.5_Back 561 - 966 0
B Inactive DFGin BLAminus out-out in-out U4N Type1.5_Back 562 - 963 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       553        563        573        583 
gamgsspsle qddgdeetSV VIVGKISFCP KDVLGHgaeg 
       593        603        613        623 
TIVYRGMFDN RDVAVKRILP ECFSFADREV QLLRESDEHP 
       633        643        653        663 
NVIRYFCTEK DRQFQYIAIE LCAATLQEYV EQkdfahlGL 
       673        683        693        703 
EPITLLQQTT SGLAHLHSLN IVHRDLKPHN ILISMPNAHG 
       713        723        733        743 
KIKAMISDFG LCKKLAVGRH SFSRRSGVPG TEGWIAPEML 
       753        763        773        783 
SEDCKENPTY TVDIFSAGCV FYYVISEGSH PFGKSLQRQA 
       793        803        813        823 
NILLGACSLD CLHPEKHEDV IARELIEKMI AMDPQKRPSA 
       833        843        853        863 
KHVLKHPFFW SLEKQLQFFQ DVSDRIEKES LDGPIVKQLE 
       873        883        893        903 
RGGRAVVKMD WRENITVPLQ TDLRKFRTYK GGSVRDLLRA 
       913        923        933        943 
MRNKKHHYRE LPAEVRETLG SLPDDFVCYF TSRFPHLLAH 
       953        963        973 
TYRAMELCSH ERLFQPYYFH eppepqppvt pdal
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None