Protein kinases in complex with XIN (Nintedanib)

Total number of genes: 4
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 4 5TE0A
DFGout None 1 3C7QA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 5MAFA 2.8 None DFGin BLAminus in-in out-none XIN Type1.5_Back
OTHER AAK1 AAK1_HUMAN AP2-associated protein kinase 1 5TE0A 1.9 Active DFGin BLAminus in-in in-in XIN Type1
TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3C7QA 2.1 Inactive DFGout None in-in none-out XIN Type1
TYR RET RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor Ret 6NECA 1.87 Active DFGin BLAminus in-in in-in XIN Type1.5_Back
TYR RET RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor Ret 6NECC 1.87 Active DFGin BLAminus in-in in-in XIN Type1.5_Back

Protein kinases in complex with XIN

Total number of genes: 4
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 4 5TE0A
DFGout None 1 3C7QA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 5MAFA 2.8 None DFGin BLAminus in-in out-none XIN Type1.5_Back
Homo sapiens OTHER AAK1 AAK1_HUMAN AP2-associated protein kinase 1 5TE0A 1.9 Active DFGin BLAminus in-in in-in XIN Type1
Homo sapiens TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3C7QA 2.1 Inactive DFGout None in-in none-out XIN Type1
Homo sapiens TYR RET RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor Ret 6NECA 1.87 Active DFGin BLAminus in-in in-in XIN Type1.5_Back
Homo sapiens TYR RET RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor Ret 6NECC 1.87 Active DFGin BLAminus in-in in-in XIN Type1.5_Back

Protein kinases in complex with XIN

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type