3UIU

EIF2AK2 (Interferon-induced, double-stranded RNA-activated protein kinase)
Group: OTHER
Uniprot: E2AK2_HUMAN
Organism: Homo sapiens
Domain boundary: 267 - 538
Resolu: 2.903

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None in-none in-none No_ligand No_ligand 254 - 541 11
B Inactive DFGin None in-none in-none No_ligand No_ligand 254 - 541 11
Representative sequence - Chain B
263 273 283 293
ETKYTVDKRF GMDFKEIELI GSGGFGQVFK AKHRIDGKTY
303 313 323 333
VIRRVKYNNE KAEREVKALA KLDHVNIVHY NGCWDGFDYD
343 353 363 373
PETsddsles sdydpenskn sSRSKTKCLF IQMEFCDKGT
383 393 403 413
LEQWIEKRRG EKLDKVLALE LFEQITKGVD YIHSKKLIHR
423 433 443 453
DLKPSNIFLV DTKQVKIGDF GLVTSLkndg krtrskgTLR
463 473 483 493
YMSPEQIssq dYGKEVDLYA LGLILAELLH VCDTAFETSK
503 513 523 533
FFTDLRDGII SDIFDKKEKT LLQKLLSKKP EDRPNTSEIL
543 -
RTLTVWKKsp eknerhtcvl hhhhhh
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None