7QQ6

EIF2AK4 (eIF-2-alpha kinase GCN2)
Group: OTHER
Uniprot: E2AK4_HUMAN
Organism: Homo sapiens
Domain boundary: 590 - 1001
Resolu: 2.8

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None out-out none-out 38O Type1 584 - 1004 0
B Inactive DFGin None out-out none-out 38O Type1 584 - 1006 0
C Inactive DFGin None out-out out-out 38O Type1 584 - 1006 0
D Inactive DFGin None out-out out-none 38O Type1 584 - 1006 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
       584        594        604        614 
gssetqrqfS RYFIEFEELQ LLGKGAFGAV IKVQNKLDGC 
       624        634        644        654 
CYAVKRIPIN PASRQFRRIK GEVTLLSRLH HENIVRYYNA 
       790        800        810        820 
WIERHERPsv ttEAVHYLYI QMEYCEKSTL RDTIDQGLYR 
       830        840        850        860 
DTVRLWRLFR EILDGLAYIH EKGMIHRNLK PVNIFLDSDD 
       870        880        890        900 
HVKIGDFGLA TDHLAfsads kqddqtgdli ksdpsghltg 
       910        920        930        940 
mvgtALYVSP EVQgstkSAY NQKVDLFSLG IIFFEMSYHP 
       950        960        970        980 
MVTASERIFV LNQLRDPTSP KFPEDFDDGE HAKQKSVISW 
       990       1000       1010       1020 
LLNHDPAKRP TATELLKSEL LPPPQMeese lhevlhhtlt


Lower-case residues are disordered in structure.
Mutations: D848N
Phosphorylation: None