Protein kinases with BABtrans conformation in complex with All ligands

Total number of genes: 10
Total number of chains: 24
AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
BABtrans 0 1 0 0 4 0 2 0 16 1 7YC9A
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Group Gene UniprotID Protein name PDB Resolution Activity Label Chelix-SaltBridge ActloopNT-ActLoopCT Ligand Type
CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 4IXPA 2.749 Inactive out-none out-out No_ligand No_ligand
NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4APCA 2.1 Inactive out-none out-out No_ligand No_ligand
NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4APCB 2.1 Inactive out-out out-out No_ligand No_ligand
NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4B9DA 1.9 Inactive out-none out-out CK7 Type1
NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4B9DB 1.9 Inactive out-out out-out CK7 Type1
OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKH 2.3 Inactive out-out out-out G41 Type1
STE MAP3K5 M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 2CLQA 2.3 Inactive out-out in-in STU Type1
STE MAP3K5 M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 2CLQB 2.3 Inactive in-none in-in STU Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7XA 2.0 Inactive in-out out-in 8DW Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7XB 2.0 Inactive in-out out-in 8DW Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4XEYB 2.891 Inactive in-out out-in 1N1 Type1
TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 3SXRA 2.4 Inactive out-out in-in 1N1 Type1
TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 3SXRB 2.4 Inactive out-out in-in 1N1 Type1
TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 3SXSA 1.89 Inactive out-out in-in PP2 Type1
TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 6I99A 2.001 Inactive out-out in-in H88 Type1
TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 6I99B 2.001 Inactive out-out in-in H88 Type1
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5XYZA 2.64 Inactive out-out out-in GYL Type1
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5XYZB 2.64 Inactive out-out out-in GYL Type1
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 7YC9A 1.4 Inactive out-out out-in IS4 Type1
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 3OCTA 1.95 Inactive in-out out-in 1N1 Type1
TYR CSK CSK_HUMAN Tyrosine-protein kinase CSK 1BYGA 2.4 Inactive out-out none-in STU Type1
TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 4MXXB 2.6 Inactive out-out none-in DB8 Type1
TYR TEK TIE2_HUMAN Angiopoietin-1 receptor 1FVRA 2.2 Inactive out-out out-out No_ligand No_ligand
TYR TEK TIE2_HUMAN Angiopoietin-1 receptor 1FVRB 2.2 Inactive out-out out-out No_ligand No_ligand

Protein kinases with BABtrans conformation in complex with All ligands

Total number of genes: 10
Total number of chains: 26
AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
BABtrans 0 1 0 0 4 0 2 0 18 1 7YC9A
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein name PDB Resolution Activity Label Chelix-SaltBridge ActloopNT-ActLoopCT Ligand Type
Homo sapiens CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 4IXPA 2.749 Inactive out-none out-out No_ligand No_ligand
Homo sapiens NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4APCA 2.1 Inactive out-none out-out No_ligand No_ligand
Homo sapiens NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4APCB 2.1 Inactive out-out out-out No_ligand No_ligand
Homo sapiens NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4B9DA 1.9 Inactive out-none out-out CK7 Type1
Homo sapiens NEK NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4B9DB 1.9 Inactive out-out out-out CK7 Type1
Homo sapiens OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKH 2.3 Inactive out-out out-out G41 Type1
Homo sapiens STE MAP3K5 M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 2CLQA 2.3 Inactive out-out in-in STU Type1
Homo sapiens STE MAP3K5 M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 2CLQB 2.3 Inactive in-none in-in STU Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7XA 2.0 Inactive in-out out-in 8DW Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7XB 2.0 Inactive in-out out-in 8DW Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4XEYB 2.891 Inactive in-out out-in 1N1 Type1
Homo sapiens TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 3SXRA 2.4 Inactive out-out in-in 1N1 Type1
Homo sapiens TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 3SXRB 2.4 Inactive out-out in-in 1N1 Type1
Homo sapiens TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 3SXSA 1.89 Inactive out-out in-in PP2 Type1
Homo sapiens TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 6I99A 2.001 Inactive out-out in-in H88 Type1
Homo sapiens TYR BMX BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX 6I99B 2.001 Inactive out-out in-in H88 Type1
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5XYZA 2.64 Inactive out-out out-in GYL Type1
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5XYZB 2.64 Inactive out-out out-in GYL Type1
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 7YC9A 1.4 Inactive out-out out-in IS4 Type1
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 3OCTA 1.95 Inactive in-out out-in 1N1 Type1
Homo sapiens TYR CSK CSK_HUMAN Tyrosine-protein kinase CSK 1BYGA 2.4 Inactive out-out none-in STU Type1
Homo sapiens TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 4MXXB 2.6 Inactive out-out none-in DB8 Type1
Homo sapiens TYR TEK TIE2_HUMAN Angiopoietin-1 receptor 1FVRA 2.2 Inactive out-out out-out No_ligand No_ligand
Homo sapiens TYR TEK TIE2_HUMAN Angiopoietin-1 receptor 1FVRB 2.2 Inactive out-out out-out No_ligand No_ligand
Mus musculus TYR BTK BTK_MOUSE Tyrosine-protein kinase BTK 8S9FA 2.6 Inactive out-out out-none 1N1 Type1
Mus musculus TYR BTK BTK_MOUSE Tyrosine-protein kinase BTK 8S9FB 2.6 Inactive out-out out-out 1N1 Type1

Protein kinases with BABtrans conformation in complex with All ligands

Total number of genes: 1
Total number of chains: 2
AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
BABtrans 0 0 0 0 0 0 0 0 2 0 8S9FB
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein name PDB Resolution Activity Label Chelix-SaltBridge ActloopNT-ActLoopCT Ligand Type
Mus musculus TYR BTK BTK_MOUSE Tyrosine-protein kinase BTK 8S9FA 2.6 Inactive out-out out-none 1N1 Type1
Mus musculus TYR BTK BTK_MOUSE Tyrosine-protein kinase BTK 8S9FB 2.6 Inactive out-out out-out 1N1 Type1