Ligand

Protein kinases in complex with P48 (Milciclib)

Total number of genes: 3

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	4	5VD1A

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	2WIHA	2.5	Active	DFGin	BLAminus	in-in	in-in	P48	Type1
CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	2WIHC	2.5	Active	DFGin	BLAminus	in-in	in-in	P48	Type1
OTHER	PKMYT1	PMYT1_HUMAN	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	5VD1A	1.7	Active	DFGin	BLAminus	in-in	in-in	P48	Type1
OTHER	WEE1	WEE1_HUMAN	Wee1-like protein kinase	5VC6A	2.0	Active	DFGin	BLAminus	in-in	in-in	P48	Type1

Protein kinases in complex with P48

Total number of genes: 3

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	4	5VD1A

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	2WIHA	2.5	Active	DFGin	BLAminus	in-in	in-in	P48	Type1
Homo sapiens	CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	2WIHC	2.5	Active	DFGin	BLAminus	in-in	in-in	P48	Type1
Homo sapiens	OTHER	PKMYT1	PMYT1_HUMAN	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	5VD1A	1.7	Active	DFGin	BLAminus	in-in	in-in	P48	Type1
Homo sapiens	OTHER	WEE1	WEE1_HUMAN	Wee1-like protein kinase	5VC6A	2.0	Active	DFGin	BLAminus	in-in	in-in	P48	Type1

Protein kinases in complex with P48

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type