Protein kinases in complex with A

Total number of genes: 54
Total number of chains: 165
Spatial Dihedral Chains Representative
DFGin BLAminus 94 3SA0A
DFGin ABAminus 13 8R4VB
DFGin BLBminus 3 3QQHA
DFGin BLBplus 26 6E4FA
DFGin None 17 6OAVA
DFGout BBAminus 7 5HG9A
DFGout None 4 3VNTA
None None 1 4E8AA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTA 2.214 None DFGin BLAminus in-in in-none VFA Type1
AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTB 2.214 None DFGin BLAminus in-in in-none VFA Type1
AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTC 2.214 Inactive DFGin BLAminus in-in in-out VFA Type1
AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTD 2.214 None DFGin BLAminus in-in in-none VFA Type1
AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTE 2.214 None DFGin BLAminus in-in in-none VFA Type1
AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTF 2.214 Active DFGin BLAminus in-in in-in VFA Type1
AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTG 2.214 None DFGin BLAminus in-in in-none VFA Type1
AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTH 2.214 Active DFGin BLAminus in-in in-in VFA Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 6I2UA 2.5 Inactive DFGin BLAminus in-in in-out COA Type1
CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 2E9VA 2.0 Active DFGin BLAminus in-in in-in 85A Type1
CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 2E9VB 2.0 Active DFGin BLAminus in-in in-in 85A Type1
CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 2E9PA 2.6 Active DFGin BLAminus in-in in-in 77A Type1
CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 2E9NA 2.5 Inactive DFGin BLAminus in-out in-in 76A Type1.5_Back
CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 2AYPA 2.9 Active DFGin BLAminus in-in in-in 43A Type1.5_Back
CAMK CHEK2 CHK2_HUMAN Serine/threonine-protein kinase Chk2 2W7XA 2.07 Inactive DFGin BLAminus out-out in-out D1A Type1
CAMK DAPK3 DAPK3_HUMAN Death-associated protein kinase 3 2J90A 2.0 Inactive DFGin BLAminus in-in in-out IZA Type1
CAMK DAPK3 DAPK3_HUMAN Death-associated protein kinase 3 2J90B 2.0 Inactive DFGin BLAminus in-in in-out IZA Type1
CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 5M5AA 1.9 None DFGin BLAminus in-in in-none KSA Type1
CAMK MKNK2 MKNK2_HUMAN MAP kinase-interacting serine/threonine-protein kinase 2 6CJEA 3.36 Inactive DFGin BLBplus in-in none-out F4A Type1
CAMK PIM1 PIM1_HUMAN Serine/threonine-protein kinase pim-1 4RC3A 2.338 Inactive DFGin ABAminus in-in in-in 3OA Type1
CAMK PIM1 PIM1_HUMAN Serine/threonine-protein kinase pim-1 4K0YA 1.954 Active DFGin BLAminus in-in in-in 1OA Type1
CAMK PIM1 PIM1_HUMAN Serine/threonine-protein kinase pim-1 4GW8A 2.0 Active DFGin BLAminus in-in in-in 3RA Type1
CAMK PLK1 PLK1_HUMAN Serine/threonine-protein kinase PLK1 3THBA 2.5 Inactive DFGin BLAminus in-in in-out 3TA Type1
CAMK SIK3 SIK3_HUMAN Serine/threonine-protein kinase SIK3 8R4VB 1.9 Inactive DFGin ABAminus out-out in-in XWA Type1
CAMK SIK3 SIK3_HUMAN Serine/threonine-protein kinase SIK3 8R4VC 1.9 Inactive DFGin ABAminus out-out in-in XWA Type1
CAMK SIK3 SIK3_HUMAN Serine/threonine-protein kinase SIK3 8R4VA 1.9 Inactive DFGin BLAminus out-out in-in XWA Type1
CK1 VRK1 VRK1_HUMAN Serine/threonine-protein kinase VRK1 6VZHB 2.55 Active DFGin BLAminus in-in in-in RYA Type1.5_Back
CK1 VRK1 VRK1_HUMAN Serine/threonine-protein kinase VRK1 6VZHD 2.55 Active DFGin BLAminus in-in in-in RYA Type1.5_Back
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3EOCA 3.2 Active DFGin BLAminus in-in in-in T2A Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3EOCC 3.2 Active DFGin BLAminus in-in in-in T2A Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QTWA 1.85 Inactive DFGin BLAminus out-out out-out X3A Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2FVDA 1.85 Inactive DFGin BLBminus out-out none-out LIA Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2VTQA 1.9 Inactive DFGin BLBminus out-out none-out LZA Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QQHA 1.87 Inactive DFGin BLBminus out-out out-out X0A Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QWJA 1.75 Inactive DFGin None out-out out-out X6A Type1
CMGC CDK6 CDK6_HUMAN Cyclin-dependent kinase 6 6OQLA 2.707 Inactive DFGin BLBplus out-out none-out N1A Type1
CMGC CLK3 CLK3_HUMAN Dual specificity protein kinase CLK3 3RAWA 2.09 Active DFGin BLAminus in-in in-in 3RA Type1
CMGC CLK3 CLK3_HUMAN Dual specificity protein kinase CLK3 3RAWB 2.09 Active DFGin BLAminus in-in in-in 3RA Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MO7A 2.15 Active DFGin BLAminus in-in in-in YRA Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8BGCA 2.8 Active DFGin BLAminus in-in in-in QIA Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8BGCB 2.8 Active DFGin BLAminus in-in in-in QIA Type1
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4AZEA 3.15 Active DFGin BLAminus in-in in-in 3RA Type1
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4AZEB 3.15 Active DFGin BLAminus in-in in-in 3RA Type1
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4AZEC 3.15 Active DFGin BLAminus in-in in-in 3RA Type1
CMGC DYRK2 DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 4AZFA 2.55 Active DFGin BLAminus in-in in-in 3RA Type1
CMGC DYRK2 DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 5LXCA 2.15 Active DFGin BLAminus in-in in-in 7AA Type1
CMGC DYRK2 DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 5LXCB 2.15 Active DFGin BLAminus in-in in-in 7AA Type1
CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 6V6LA 2.19 Active DFGin BLAminus in-in in-in QQA Type1
CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 5HLPA 2.45 Active DFGin BLAminus in-in in-in 65A Type1
CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 5HLPB 2.45 Active DFGin BLAminus in-in in-in 65A Type1
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 3SA0A 1.595 Active DFGin BLAminus out-in in-in NRA Type1
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 2OJGA 2.0 Active DFGin BLAminus in-in in-in 19A Type1
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 2OJIA 2.6 Active DFGin BLAminus out-in in-in 33A Type1
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 2OJJA 2.4 Active DFGin BLAminus in-in in-in 82A Type1
CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 2OK1A 2.4 Inactive DFGin ABAminus out-out none-out 33A Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2BALA 2.1 Inactive DFGin BLBplus in-in none-out PQA Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4KIQA 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4KIQB 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4KIQC 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4KIQD 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3E92A 2.0 Inactive DFGin BLBplus in-in none-out G6A Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ROCA 1.7 Inactive DFGin BLBplus in-out none-out 29A 29B Type1 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4E8AA 2.7 Inactive None None in-in none-none 0OA Allosteric
CMGC MAPK8 MK08_HUMAN Mitogen-activated protein kinase 8 3O2MA 2.7 Active DFGin BLAminus in-in in-in 46A Allosteric
CMGC MAPK8 MK08_HUMAN Mitogen-activated protein kinase 8 3O2MB 2.7 Active DFGin BLAminus in-in in-in 46A Allosteric
CMGC SRPK1 SRPK1_HUMAN SRSF protein kinase 1 5MXXA 1.75 Active DFGin BLAminus in-in in-in W4A Type1
CMGC SRPK2 SRPK2_HUMAN SRSF protein kinase 2 5MYVA 2.9 Active DFGin BLAminus in-in in-in W4A Type1
CMGC SRPK2 SRPK2_HUMAN SRSF protein kinase 2 5MYVB 2.9 Active DFGin BLAminus in-in in-in W4A Type1
CMGC SRPK2 SRPK2_HUMAN SRSF protein kinase 2 5MYVC 2.9 Active DFGin BLAminus in-in in-in W4A Type1
CMGC SRPK2 SRPK2_HUMAN SRSF protein kinase 2 5MYVD 2.9 Active DFGin BLAminus in-in in-in W4A Type1
OTHER AAK1 AAK1_HUMAN AP2-associated protein kinase 1 4WSQA 1.95 Active DFGin BLAminus in-in in-in KSA Type1
OTHER AAK1 AAK1_HUMAN AP2-associated protein kinase 1 4WSQB 1.95 Active DFGin BLAminus in-in in-in KSA Type1
OTHER IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4KIKA 2.83 None DFGin BLAminus in-in none-out KSA Type1
OTHER IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4KIKB 2.83 Active DFGin BLAminus in-in in-in KSA Type1
OTHER TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP5A 2.8 Inactive DFGin ABAminus out-out none-out 7RO 1KA Type1 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQFA 2.7 Inactive DFGin BLBplus out-out out-out KSA Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3E8NA 2.5 Inactive DFGin BLBplus out-out out-out ATP VRA Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0WB 3.09 Inactive DFGin BLBplus out-out out-out ANP QOA Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 2P55A 2.8 Inactive DFGin BLBplus out-out out-out MRA ATP Type3 Type1
STE MAP2K2 MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 1S9IA 3.2 Inactive DFGin BLBplus out-out out-out ATP 5EA Type1 Type3
STE MAP2K2 MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 1S9IB 3.2 Inactive DFGin BLBplus out-out out-none ATP 5EA Type1 Type3
STE MAP3K8 M3K8_HUMAN Mitogen-activated protein kinase kinase kinase 8 5IU2A 2.7 Inactive DFGin BLAminus in-out in-in 6DA Type1
STE MAP3K8 M3K8_HUMAN Mitogen-activated protein kinase kinase kinase 8 5IU2B 2.7 Inactive DFGin BLAminus in-out in-in 6DA Type1
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 4W8DA 1.77 Active DFGin BLAminus in-in in-in 3JA Type1
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7EB 1.32 Inactive DFGin BLAminus in-out in-in LU8 XEA Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7XB 1.3 Inactive DFGin BLAminus in-out in-in LU8 LGA Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7XA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 LGA Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S76A 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 02A 02A Type1 Allosteric Allosteric Allosteric Type1.5_Back
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S76B 1.31 Inactive DFGin BLAminus in-out in-in LU8 02A Type1 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4DBNA 3.15 Inactive DFGout BBAminus in-in none-out 0JA Type2
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4DBNB 3.15 Inactive DFGout BBAminus in-in out-out 0JA Type2
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6EGAA 2.512 Inactive DFGout None in-in none-in J8A Type2
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6EGAB 2.512 Inactive DFGout None in-in none-in J8A Type2
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 4NEUA 2.57 Inactive DFGout BBAminus in-in out-in Q1A Type2
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 4NEUB 2.57 Inactive DFGout BBAminus in-in none-none Q1A Type2
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OA 2.89 None DFGin BLAminus in-none in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OB 2.89 None DFGin BLAminus in-none in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OC 2.89 None DFGin BLAminus in-none in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OD 2.89 None DFGin BLAminus in-none in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OE 2.89 Inactive DFGin BLAminus in-in in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OF 2.89 None DFGin BLAminus in-none in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OG 2.89 None DFGin BLAminus in-none in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OH 2.89 Inactive DFGin BLAminus in-in in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OI 2.89 None DFGin BLAminus in-none in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OJ 2.89 Inactive DFGin BLAminus in-in in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OK 2.89 Inactive DFGin BLAminus in-in in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OL 2.89 Inactive DFGin BLAminus in-in in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OM 2.89 None DFGin BLAminus in-none in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5ON 2.89 None DFGin BLAminus in-none in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OO 2.89 Inactive DFGin BLAminus in-in in-out 9XA Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OP 2.89 None DFGin BLAminus in-none in-out 9XA Type1
TKL TGFBR1 TGFR1_HUMAN TGF-beta receptor type-1 4X0MA 1.68 Active DFGin BLAminus in-in in-in 3WA Type1
TKL TGFBR1 TGFR1_HUMAN TGF-beta receptor type-1 6B8YA 1.65 Active DFGin BLAminus in-in in-in D0A Type1.5_Back
TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 7JYRA 2.32 Inactive DFGin ABAminus in-out out-out VTA Type1
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 7LTZA 1.53 Inactive DFGin BLBplus out-out out-out YDA Type1
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6W07A 1.51 Inactive DFGin BLBplus out-out out-out S9A Type1
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6DI3A 2.0 Inactive DFGin BLBplus out-out out-out GJA Type1.5_Back
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6E4FA 1.15 Inactive DFGin BLBplus out-out out-out HRA Type1.5_Back
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7VRAA 2.41 Active DFGin BLAminus in-in in-in I0A Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXA 2.3 Inactive DFGin BLBplus out-out none-out ANP YFA Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXB 2.3 Inactive DFGin BLBplus out-out out-in ANP YFA Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXC 2.3 Inactive DFGin BLBplus out-out none-in ANP YFA Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXD 2.3 Inactive DFGin BLBplus out-out out-in ANP YFA Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8FV4D 2.2 Inactive DFGin BLBplus out-out out-in YAA Type1.5_Back
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6WAKC 2.4 Inactive DFGin BLBplus out-out none-out TQA Type1.5_Front
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5HG9A 2.15 Inactive DFGout BBAminus out-out in-in 63A Type1
TYR HCK HCK_HUMAN Tyrosine-protein kinase HCK 3VS1B 2.464 Inactive DFGin None out-out out-none VSA Type1
TYR HCK HCK_HUMAN Tyrosine-protein kinase HCK 3VS1A 2.464 Inactive DFGin None out-out out-none VSA Type1.5_Back
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNA 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNB 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNC 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZND 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNE 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNF 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNG 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNH 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 8PYJAAA 2.702 Inactive DFGout None in-out out-in IEA Type2
TYR INSR INSR_HUMAN Insulin receptor 5E1SA 2.264 Inactive DFGin None in-out none-out 5JA Type1
TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 3QGWB 2.1 Inactive DFGin None in-out none-none L7A Type1
TYR JAK1 JAK1_HUMAN Tyrosine-protein kinase JAK1 3EYHA 2.0 Inactive DFGin ABAminus in-in in-in IZA Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 2B7AA 2.0 Inactive DFGin ABAminus in-in in-in IZA Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 2B7AB 2.0 Inactive DFGin ABAminus in-in in-in IZA Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 4AQCA 1.9 Inactive DFGin ABAminus in-in in-in 88A Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 4AQCB 1.9 Inactive DFGin ABAminus in-in in-in 88A Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6VNEA 2.32 Inactive DFGin ABAminus in-in in-in 2TA Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6VNEB 2.32 Inactive DFGin ABAminus in-in in-out 2TA Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6OAVA 1.939 Inactive DFGin None in-none out-out M3A Type1
TYR JAK3 JAK3_HUMAN Tyrosine-protein kinase JAK3 6NY4A 2.33 Active DFGin BLAminus in-in in-in Z3A Type1
TYR JAK3 JAK3_HUMAN Tyrosine-protein kinase JAK3 3LXLA 1.74 Active DFGin BLAminus in-in in-in IZA Type1
TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3VNTA 1.64 Inactive DFGout None in-in out-in 0JA Type2
TYR KIT KIT_HUMAN Mast/stem cell growth factor receptor Kit 8PQAA 1.65 Active DFGin BLAminus in-in in-in 98A Type1
TYR KIT KIT_HUMAN Mast/stem cell growth factor receptor Kit 8PQAC 1.65 Active DFGin BLAminus in-in in-in 98A Type1
TYR MET MET_HUMAN Hepatocyte growth factor receptor 1R0PA 1.8 Inactive DFGin BLBplus out-out out-out KSA Type1
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6DKWA 2.91 Inactive DFGout BBAminus out-out none-in GXA Type2
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6DKWB 2.91 Inactive DFGout BBAminus in-out none-in GXA Type2
TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 4K8AA 2.91 None DFGin BLAminus in-out none-out K8A Type1
TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 4K8AB 2.91 Inactive DFGin BLAminus in-out out-out K8A Type1
TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 4KABB 2.71 Inactive DFGin BLAminus in-in out-out 4KA Type1
TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 4KABA 2.71 Inactive DFGin None in-in none-out 4KA Type1
TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 2BDFA 2.1 Active DFGin BLAminus in-in in-in 24A Type1
TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 2BDFB 2.1 Active DFGin BLAminus in-in in-in 24A Type1
TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 3LXPA 1.65 Active DFGin BLAminus in-in in-in IZA Type1
TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 3NZ0A 2.0 Active DFGin BLAminus in-in in-in IZA Type1
TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 6NZHA 2.73 Inactive DFGin None in-none out-out L9A Type1
TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 6NZHB 2.73 Inactive DFGin None in-none out-out L9A Type1

Protein kinases in complex with A

Total number of genes: 62
Total number of chains: 199
Spatial Dihedral Chains Representative
DFGin BLAminus 116 5N3HA
DFGin ABAminus 17 4C2VA
DFGin BLBminus 3 3QQHA
DFGin BLBplus 26 6E4FA
DFGin None 19 6OAVA
DFGout BBAminus 9 5HG9A
DFGout None 4 3VNTA
None None 5 3UPZA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2F7EE 2.0 Active DFGin BLAminus in-in in-in 2EA Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2F7XE 1.9 Active DFGin BLAminus in-in in-in 4EA Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2F7ZE 3.0 Active DFGin BLAminus in-in in-in 6EA Type1
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3HA 1.36 Active DFGin BLAminus in-in in-in NCA Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3UQGA 2.2 None DFGin BLAminus in-in in-none B5A Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3UQGB 2.2 None DFGin BLAminus in-in in-none B5A Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 5T0PA 2.5 Inactive DFGin None in-out in-none 73A Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 5T0PB 2.5 Inactive DFGin None in-out in-none 73A Type1
Homo sapiens AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTA 2.214 None DFGin BLAminus in-in in-none VFA Type1
Homo sapiens AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTB 2.214 None DFGin BLAminus in-in in-none VFA Type1
Homo sapiens AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTC 2.214 Inactive DFGin BLAminus in-in in-out VFA Type1
Homo sapiens AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTD 2.214 None DFGin BLAminus in-in in-none VFA Type1
Homo sapiens AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTE 2.214 None DFGin BLAminus in-in in-none VFA Type1
Homo sapiens AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTF 2.214 Active DFGin BLAminus in-in in-in VFA Type1
Homo sapiens AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTG 2.214 None DFGin BLAminus in-in in-none VFA Type1
Homo sapiens AGC ROCK2 ROCK2_HUMAN Rho-associated protein kinase 2 7JNTH 2.214 Active DFGin BLAminus in-in in-in VFA Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6I2UA 2.5 Inactive DFGin BLAminus in-in in-out COA Type1
Homo sapiens CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 2E9VA 2.0 Active DFGin BLAminus in-in in-in 85A Type1
Homo sapiens CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 2E9VB 2.0 Active DFGin BLAminus in-in in-in 85A Type1
Homo sapiens CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 2E9PA 2.6 Active DFGin BLAminus in-in in-in 77A Type1
Homo sapiens CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 2E9NA 2.5 Inactive DFGin BLAminus in-out in-in 76A Type1.5_Back
Homo sapiens CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 2AYPA 2.9 Active DFGin BLAminus in-in in-in 43A Type1.5_Back
Homo sapiens CAMK CHEK2 CHK2_HUMAN Serine/threonine-protein kinase Chk2 2W7XA 2.07 Inactive DFGin BLAminus out-out in-out D1A Type1
Homo sapiens CAMK DAPK3 DAPK3_HUMAN Death-associated protein kinase 3 2J90A 2.0 Inactive DFGin BLAminus in-in in-out IZA Type1
Homo sapiens CAMK DAPK3 DAPK3_HUMAN Death-associated protein kinase 3 2J90B 2.0 Inactive DFGin BLAminus in-in in-out IZA Type1
Homo sapiens CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 5M5AA 1.9 None DFGin BLAminus in-in in-none KSA Type1
Homo sapiens CAMK MKNK2 MKNK2_HUMAN MAP kinase-interacting serine/threonine-protein kinase 2 6CJEA 3.36 Inactive DFGin BLBplus in-in none-out F4A Type1
Homo sapiens CAMK PIM1 PIM1_HUMAN Serine/threonine-protein kinase pim-1 4RC3A 2.338 Inactive DFGin ABAminus in-in in-in 3OA Type1
Homo sapiens CAMK PIM1 PIM1_HUMAN Serine/threonine-protein kinase pim-1 4K0YA 1.954 Active DFGin BLAminus in-in in-in 1OA Type1
Homo sapiens CAMK PIM1 PIM1_HUMAN Serine/threonine-protein kinase pim-1 4GW8A 2.0 Active DFGin BLAminus in-in in-in 3RA Type1
Homo sapiens CAMK PLK1 PLK1_HUMAN Serine/threonine-protein kinase PLK1 3THBA 2.5 Inactive DFGin BLAminus in-in in-out 3TA Type1
Homo sapiens CAMK SIK3 SIK3_HUMAN Serine/threonine-protein kinase SIK3 8R4VB 1.9 Inactive DFGin ABAminus out-out in-in XWA Type1
Homo sapiens CAMK SIK3 SIK3_HUMAN Serine/threonine-protein kinase SIK3 8R4VC 1.9 Inactive DFGin ABAminus out-out in-in XWA Type1
Homo sapiens CAMK SIK3 SIK3_HUMAN Serine/threonine-protein kinase SIK3 8R4VA 1.9 Inactive DFGin BLAminus out-out in-in XWA Type1
Homo sapiens CK1 VRK1 VRK1_HUMAN Serine/threonine-protein kinase VRK1 6VZHB 2.55 Active DFGin BLAminus in-in in-in RYA Type1.5_Back
Homo sapiens CK1 VRK1 VRK1_HUMAN Serine/threonine-protein kinase VRK1 6VZHD 2.55 Active DFGin BLAminus in-in in-in RYA Type1.5_Back
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3EOCA 3.2 Active DFGin BLAminus in-in in-in T2A Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3EOCC 3.2 Active DFGin BLAminus in-in in-in T2A Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QTWA 1.85 Inactive DFGin BLAminus out-out out-out X3A Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2FVDA 1.85 Inactive DFGin BLBminus out-out none-out LIA Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2VTQA 1.9 Inactive DFGin BLBminus out-out none-out LZA Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QQHA 1.87 Inactive DFGin BLBminus out-out out-out X0A Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QWJA 1.75 Inactive DFGin None out-out out-out X6A Type1
Homo sapiens CMGC CDK6 CDK6_HUMAN Cyclin-dependent kinase 6 6OQLA 2.707 Inactive DFGin BLBplus out-out none-out N1A Type1
Homo sapiens CMGC CLK3 CLK3_HUMAN Dual specificity protein kinase CLK3 3RAWA 2.09 Active DFGin BLAminus in-in in-in 3RA Type1
Homo sapiens CMGC CLK3 CLK3_HUMAN Dual specificity protein kinase CLK3 3RAWB 2.09 Active DFGin BLAminus in-in in-in 3RA Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MO7A 2.15 Active DFGin BLAminus in-in in-in YRA Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8BGCA 2.8 Active DFGin BLAminus in-in in-in QIA Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8BGCB 2.8 Active DFGin BLAminus in-in in-in QIA Type1
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4AZEA 3.15 Active DFGin BLAminus in-in in-in 3RA Type1
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4AZEB 3.15 Active DFGin BLAminus in-in in-in 3RA Type1
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4AZEC 3.15 Active DFGin BLAminus in-in in-in 3RA Type1
Homo sapiens CMGC DYRK2 DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 4AZFA 2.55 Active DFGin BLAminus in-in in-in 3RA Type1
Homo sapiens CMGC DYRK2 DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 5LXCA 2.15 Active DFGin BLAminus in-in in-in 7AA Type1
Homo sapiens CMGC DYRK2 DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 5LXCB 2.15 Active DFGin BLAminus in-in in-in 7AA Type1
Homo sapiens CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 6V6LA 2.19 Active DFGin BLAminus in-in in-in QQA Type1
Homo sapiens CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 5HLPA 2.45 Active DFGin BLAminus in-in in-in 65A Type1
Homo sapiens CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 5HLPB 2.45 Active DFGin BLAminus in-in in-in 65A Type1
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 3SA0A 1.595 Active DFGin BLAminus out-in in-in NRA Type1
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 2OJGA 2.0 Active DFGin BLAminus in-in in-in 19A Type1
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 2OJIA 2.6 Active DFGin BLAminus out-in in-in 33A Type1
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 2OJJA 2.4 Active DFGin BLAminus in-in in-in 82A Type1
Homo sapiens CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 2OK1A 2.4 Inactive DFGin ABAminus out-out none-out 33A Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2BALA 2.1 Inactive DFGin BLBplus in-in none-out PQA Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4KIQA 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4KIQB 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4KIQC 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4KIQD 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3E92A 2.0 Inactive DFGin BLBplus in-in none-out G6A Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ROCA 1.7 Inactive DFGin BLBplus in-out none-out 29A 29B Type1 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4E8AA 2.7 Inactive None None in-in none-none 0OA Allosteric
Homo sapiens CMGC MAPK8 MK08_HUMAN Mitogen-activated protein kinase 8 3O2MA 2.7 Active DFGin BLAminus in-in in-in 46A Allosteric
Homo sapiens CMGC MAPK8 MK08_HUMAN Mitogen-activated protein kinase 8 3O2MB 2.7 Active DFGin BLAminus in-in in-in 46A Allosteric
Homo sapiens CMGC SRPK1 SRPK1_HUMAN SRSF protein kinase 1 5MXXA 1.75 Active DFGin BLAminus in-in in-in W4A Type1
Homo sapiens CMGC SRPK2 SRPK2_HUMAN SRSF protein kinase 2 5MYVA 2.9 Active DFGin BLAminus in-in in-in W4A Type1
Homo sapiens CMGC SRPK2 SRPK2_HUMAN SRSF protein kinase 2 5MYVB 2.9 Active DFGin BLAminus in-in in-in W4A Type1
Homo sapiens CMGC SRPK2 SRPK2_HUMAN SRSF protein kinase 2 5MYVC 2.9 Active DFGin BLAminus in-in in-in W4A Type1
Homo sapiens CMGC SRPK2 SRPK2_HUMAN SRSF protein kinase 2 5MYVD 2.9 Active DFGin BLAminus in-in in-in W4A Type1
Homo sapiens OTHER AAK1 AAK1_HUMAN AP2-associated protein kinase 1 4WSQA 1.95 Active DFGin BLAminus in-in in-in KSA Type1
Homo sapiens OTHER AAK1 AAK1_HUMAN AP2-associated protein kinase 1 4WSQB 1.95 Active DFGin BLAminus in-in in-in KSA Type1
Homo sapiens OTHER IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4KIKA 2.83 None DFGin BLAminus in-in none-out KSA Type1
Homo sapiens OTHER IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4KIKB 2.83 Active DFGin BLAminus in-in in-in KSA Type1
Homo sapiens OTHER TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP5A 2.8 Inactive DFGin ABAminus out-out none-out 7RO 1KA Type1 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQFA 2.7 Inactive DFGin BLBplus out-out out-out KSA Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3E8NA 2.5 Inactive DFGin BLBplus out-out out-out ATP VRA Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0WB 3.09 Inactive DFGin BLBplus out-out out-out ANP QOA Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 2P55A 2.8 Inactive DFGin BLBplus out-out out-out MRA ATP Type3 Type1
Homo sapiens STE MAP2K2 MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 1S9IA 3.2 Inactive DFGin BLBplus out-out out-out ATP 5EA Type1 Type3
Homo sapiens STE MAP2K2 MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 1S9IB 3.2 Inactive DFGin BLBplus out-out out-none ATP 5EA Type1 Type3
Homo sapiens STE MAP3K8 M3K8_HUMAN Mitogen-activated protein kinase kinase kinase 8 5IU2A 2.7 Inactive DFGin BLAminus in-out in-in 6DA Type1
Homo sapiens STE MAP3K8 M3K8_HUMAN Mitogen-activated protein kinase kinase kinase 8 5IU2B 2.7 Inactive DFGin BLAminus in-out in-in 6DA Type1
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 4W8DA 1.77 Active DFGin BLAminus in-in in-in 3JA Type1
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7EB 1.32 Inactive DFGin BLAminus in-out in-in LU8 XEA Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7XB 1.3 Inactive DFGin BLAminus in-out in-in LU8 LGA Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7XA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 LGA Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S76A 1.31 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 02A 02A Type1 Allosteric Allosteric Allosteric Type1.5_Back
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S76B 1.31 Inactive DFGin BLAminus in-out in-in LU8 02A Type1 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4DBNA 3.15 Inactive DFGout BBAminus in-in none-out 0JA Type2
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4DBNB 3.15 Inactive DFGout BBAminus in-in out-out 0JA Type2
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6EGAA 2.512 Inactive DFGout None in-in none-in J8A Type2
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6EGAB 2.512 Inactive DFGout None in-in none-in J8A Type2
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 4NEUA 2.57 Inactive DFGout BBAminus in-in out-in Q1A Type2
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 4NEUB 2.57 Inactive DFGout BBAminus in-in none-none Q1A Type2
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OA 2.89 None DFGin BLAminus in-none in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OB 2.89 None DFGin BLAminus in-none in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OC 2.89 None DFGin BLAminus in-none in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OD 2.89 None DFGin BLAminus in-none in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OE 2.89 Inactive DFGin BLAminus in-in in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OF 2.89 None DFGin BLAminus in-none in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OG 2.89 None DFGin BLAminus in-none in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OH 2.89 Inactive DFGin BLAminus in-in in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OI 2.89 None DFGin BLAminus in-none in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OJ 2.89 Inactive DFGin BLAminus in-in in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OK 2.89 Inactive DFGin BLAminus in-in in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OL 2.89 Inactive DFGin BLAminus in-in in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OM 2.89 None DFGin BLAminus in-none in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5ON 2.89 None DFGin BLAminus in-none in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OO 2.89 Inactive DFGin BLAminus in-in in-out 9XA Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5W5OP 2.89 None DFGin BLAminus in-none in-out 9XA Type1
Homo sapiens TKL TGFBR1 TGFR1_HUMAN TGF-beta receptor type-1 4X0MA 1.68 Active DFGin BLAminus in-in in-in 3WA Type1
Homo sapiens TKL TGFBR1 TGFR1_HUMAN TGF-beta receptor type-1 6B8YA 1.65 Active DFGin BLAminus in-in in-in D0A Type1.5_Back
Homo sapiens TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 7JYRA 2.32 Inactive DFGin ABAminus in-out out-out VTA Type1
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 7LTZA 1.53 Inactive DFGin BLBplus out-out out-out YDA Type1
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6W07A 1.51 Inactive DFGin BLBplus out-out out-out S9A Type1
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6DI3A 2.0 Inactive DFGin BLBplus out-out out-out GJA Type1.5_Back
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6E4FA 1.15 Inactive DFGin BLBplus out-out out-out HRA Type1.5_Back
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7VRAA 2.41 Active DFGin BLAminus in-in in-in I0A Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXA 2.3 Inactive DFGin BLBplus out-out none-out ANP YFA Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXB 2.3 Inactive DFGin BLBplus out-out out-in ANP YFA Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXC 2.3 Inactive DFGin BLBplus out-out none-in ANP YFA Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXD 2.3 Inactive DFGin BLBplus out-out out-in ANP YFA Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8FV4D 2.2 Inactive DFGin BLBplus out-out out-in YAA Type1.5_Back
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6WAKC 2.4 Inactive DFGin BLBplus out-out none-out TQA Type1.5_Front
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5HG9A 2.15 Inactive DFGout BBAminus out-out in-in 63A Type1
Homo sapiens TYR HCK HCK_HUMAN Tyrosine-protein kinase HCK 3VS1B 2.464 Inactive DFGin None out-out out-none VSA Type1
Homo sapiens TYR HCK HCK_HUMAN Tyrosine-protein kinase HCK 3VS1A 2.464 Inactive DFGin None out-out out-none VSA Type1.5_Back
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNA 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNB 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNC 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZND 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNE 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNF 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNG 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 5HZNH 2.2 Inactive DFGin None out-out out-in 66A Type1.5_Front
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 8PYJAAA 2.702 Inactive DFGout None in-out out-in IEA Type2
Homo sapiens TYR INSR INSR_HUMAN Insulin receptor 5E1SA 2.264 Inactive DFGin None in-out none-out 5JA Type1
Homo sapiens TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 3QGWB 2.1 Inactive DFGin None in-out none-none L7A Type1
Homo sapiens TYR JAK1 JAK1_HUMAN Tyrosine-protein kinase JAK1 3EYHA 2.0 Inactive DFGin ABAminus in-in in-in IZA Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 2B7AA 2.0 Inactive DFGin ABAminus in-in in-in IZA Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 2B7AB 2.0 Inactive DFGin ABAminus in-in in-in IZA Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 4AQCA 1.9 Inactive DFGin ABAminus in-in in-in 88A Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 4AQCB 1.9 Inactive DFGin ABAminus in-in in-in 88A Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6VNEA 2.32 Inactive DFGin ABAminus in-in in-in 2TA Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6VNEB 2.32 Inactive DFGin ABAminus in-in in-out 2TA Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6OAVA 1.939 Inactive DFGin None in-none out-out M3A Type1
Homo sapiens TYR JAK3 JAK3_HUMAN Tyrosine-protein kinase JAK3 6NY4A 2.33 Active DFGin BLAminus in-in in-in Z3A Type1
Homo sapiens TYR JAK3 JAK3_HUMAN Tyrosine-protein kinase JAK3 3LXLA 1.74 Active DFGin BLAminus in-in in-in IZA Type1
Homo sapiens TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3VNTA 1.64 Inactive DFGout None in-in out-in 0JA Type2
Homo sapiens TYR KIT KIT_HUMAN Mast/stem cell growth factor receptor Kit 8PQAA 1.65 Active DFGin BLAminus in-in in-in 98A Type1
Homo sapiens TYR KIT KIT_HUMAN Mast/stem cell growth factor receptor Kit 8PQAC 1.65 Active DFGin BLAminus in-in in-in 98A Type1
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 1R0PA 1.8 Inactive DFGin BLBplus out-out out-out KSA Type1
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6DKWA 2.91 Inactive DFGout BBAminus out-out none-in GXA Type2
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6DKWB 2.91 Inactive DFGout BBAminus in-out none-in GXA Type2
Homo sapiens TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 4K8AA 2.91 None DFGin BLAminus in-out none-out K8A Type1
Homo sapiens TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 4K8AB 2.91 Inactive DFGin BLAminus in-out out-out K8A Type1
Homo sapiens TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 4KABB 2.71 Inactive DFGin BLAminus in-in out-out 4KA Type1
Homo sapiens TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 4KABA 2.71 Inactive DFGin None in-in none-out 4KA Type1
Homo sapiens TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 2BDFA 2.1 Active DFGin BLAminus in-in in-in 24A Type1
Homo sapiens TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 2BDFB 2.1 Active DFGin BLAminus in-in in-in 24A Type1
Homo sapiens TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 3LXPA 1.65 Active DFGin BLAminus in-in in-in IZA Type1
Homo sapiens TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 3NZ0A 2.0 Active DFGin BLAminus in-in in-in IZA Type1
Homo sapiens TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 6NZHA 2.73 Inactive DFGin None in-none out-out L9A Type1
Homo sapiens TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 6NZHB 2.73 Inactive DFGin None in-none out-out L9A Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1BKXA 2.6 Active DFGin BLAminus in-in in-in A Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P7AA 2.31 Inactive DFGout BBAminus in-in none-out P7A Type3
Mus musculus STE MAP3K14 M3K14_MOUSE Mitogen-activated protein kinase kinase kinase 14 4G3GA 2.5 Active DFGin BLAminus in-in in-in 0WA Type1
Mus musculus TYR JAK2 JAK2_MOUSE Tyrosine-protein kinase JAK2 4GL9A 3.9 Inactive DFGin BLAminus in-in in-out IZA Type1
Mus musculus TYR JAK2 JAK2_MOUSE Tyrosine-protein kinase JAK2 4GL9B 3.9 Inactive DFGin BLAminus in-in in-out IZA Type1
Mus musculus TYR JAK2 JAK2_MOUSE Tyrosine-protein kinase JAK2 4GL9C 3.9 Inactive DFGin BLAminus in-in in-out IZA Type1
Mus musculus TYR JAK2 JAK2_MOUSE Tyrosine-protein kinase JAK2 4GL9D 3.9 Active DFGin BLAminus in-in in-in IZA Type1
Rattus norvegicus CMGC MAPK1 MK01_RAT Mitogen-activated protein kinase 1 4XP0A 1.46 Active DFGin BLAminus in-in in-in 42A Type1
Rattus norvegicus CMGC MAPK1 MK01_RAT Mitogen-activated protein kinase 1 4XRLA 2.554 Active DFGin BLAminus out-in in-in 42A Type1
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ2A 3.33 Inactive DFGin ABAminus in-in in-none IZA Type1
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ2B 3.33 Inactive DFGin ABAminus in-in in-none IZA Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M11a 2.46 Active DFGin BLAminus in-in in-none 25A B49 Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M11b 2.46 Active DFGin BLAminus in-in in-none 25A B49 Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DSYa 2.651 Active DFGin BLAminus in-in in-none 25A HFX Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DSYb 2.651 Active DFGin BLAminus in-in in-none 25A HFX Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DTSa 2.63 Active DFGin BLAminus in-in in-none 25A 27K Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DTSb 2.63 Active DFGin BLAminus in-in in-none 25A 27K Allosteric Type1
Toxoplasma gondii CAMK CDPK1 Q9BJF5_TOXGO Calmodulin-domain protein kinase 1 3UPXA 2.27 Inactive None None out-out out-out B6A Type1
Toxoplasma gondii CAMK CDPK1 Q9BJF5_TOXGO Calmodulin-domain protein kinase 1 3UPZA 2.2 Inactive None None out-out out-out B5A Type1
Toxoplasma gondii CAMK CDPK1 Q9BJF5_TOXGO Calmodulin-domain protein kinase 1 4WG3A 2.2 Inactive None None out-out out-out UWA Type1
Toxoplasma gondii CAMK CDPK1 Q9BJF5_TOXGO Calmodulin-domain protein kinase 1 5T6AA 2.05 Inactive None None out-out out-out 5GA Type1
Xenopus laevis CAMK AURKBA AUKBA_XENLA Aurora kinase B-A 4C2VA 1.49 Inactive DFGin ABAminus out-out in-in YJA Type1.5_Front
Xenopus laevis CAMK AURKBA AUKBA_XENLA Aurora kinase B-A 4C2VB 1.49 Inactive DFGin ABAminus out-out in-in YJA Type1.5_Front
Zea mays CMGC ACK2 CSK2A_MAIZE Casein kinase II subunit alpha 1M2PA 2.0 Active DFGin BLAminus in-in in-in HNA Type1
Zea mays CMGC ACK2 CSK2A_MAIZE Casein kinase II subunit alpha 1OM1A 1.68 Active DFGin BLAminus in-in in-in IQA Type1
Zea mays OTHER DRIK1 C0P4K9_MAIZE Protein kinase superfamily protein 6EASA 2.0 Inactive DFGout BBAminus out-none out-none J3A Type1

Protein kinases in complex with A

Total number of genes: 12
Total number of chains: 34
Spatial Dihedral Chains Representative
DFGin BLAminus 22 5N3HA
DFGin ABAminus 4 4C2VA
DFGin None 2 5T0PA
DFGout BBAminus 2 3P7AA
None None 4 3UPZA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2F7EE 2.0 Active DFGin BLAminus in-in in-in 2EA Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2F7XE 1.9 Active DFGin BLAminus in-in in-in 4EA Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2F7ZE 3.0 Active DFGin BLAminus in-in in-in 6EA Type1
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3HA 1.36 Active DFGin BLAminus in-in in-in NCA Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3UQGA 2.2 None DFGin BLAminus in-in in-none B5A Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3UQGB 2.2 None DFGin BLAminus in-in in-none B5A Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 5T0PA 2.5 Inactive DFGin None in-out in-none 73A Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 5T0PB 2.5 Inactive DFGin None in-out in-none 73A Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1BKXA 2.6 Active DFGin BLAminus in-in in-in A Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P7AA 2.31 Inactive DFGout BBAminus in-in none-out P7A Type3
Mus musculus STE MAP3K14 M3K14_MOUSE Mitogen-activated protein kinase kinase kinase 14 4G3GA 2.5 Active DFGin BLAminus in-in in-in 0WA Type1
Mus musculus TYR JAK2 JAK2_MOUSE Tyrosine-protein kinase JAK2 4GL9A 3.9 Inactive DFGin BLAminus in-in in-out IZA Type1
Mus musculus TYR JAK2 JAK2_MOUSE Tyrosine-protein kinase JAK2 4GL9B 3.9 Inactive DFGin BLAminus in-in in-out IZA Type1
Mus musculus TYR JAK2 JAK2_MOUSE Tyrosine-protein kinase JAK2 4GL9C 3.9 Inactive DFGin BLAminus in-in in-out IZA Type1
Mus musculus TYR JAK2 JAK2_MOUSE Tyrosine-protein kinase JAK2 4GL9D 3.9 Active DFGin BLAminus in-in in-in IZA Type1
Rattus norvegicus CMGC MAPK1 MK01_RAT Mitogen-activated protein kinase 1 4XP0A 1.46 Active DFGin BLAminus in-in in-in 42A Type1
Rattus norvegicus CMGC MAPK1 MK01_RAT Mitogen-activated protein kinase 1 4XRLA 2.554 Active DFGin BLAminus out-in in-in 42A Type1
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ2A 3.33 Inactive DFGin ABAminus in-in in-none IZA Type1
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ2B 3.33 Inactive DFGin ABAminus in-in in-none IZA Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M11a 2.46 Active DFGin BLAminus in-in in-none 25A B49 Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M11b 2.46 Active DFGin BLAminus in-in in-none 25A B49 Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DSYa 2.651 Active DFGin BLAminus in-in in-none 25A HFX Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DSYb 2.651 Active DFGin BLAminus in-in in-none 25A HFX Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DTSa 2.63 Active DFGin BLAminus in-in in-none 25A 27K Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DTSb 2.63 Active DFGin BLAminus in-in in-none 25A 27K Allosteric Type1
Toxoplasma gondii CAMK CDPK1 Q9BJF5_TOXGO Calmodulin-domain protein kinase 1 3UPXA 2.27 Inactive None None out-out out-out B6A Type1
Toxoplasma gondii CAMK CDPK1 Q9BJF5_TOXGO Calmodulin-domain protein kinase 1 3UPZA 2.2 Inactive None None out-out out-out B5A Type1
Toxoplasma gondii CAMK CDPK1 Q9BJF5_TOXGO Calmodulin-domain protein kinase 1 4WG3A 2.2 Inactive None None out-out out-out UWA Type1
Toxoplasma gondii CAMK CDPK1 Q9BJF5_TOXGO Calmodulin-domain protein kinase 1 5T6AA 2.05 Inactive None None out-out out-out 5GA Type1
Xenopus laevis CAMK AURKBA AUKBA_XENLA Aurora kinase B-A 4C2VA 1.49 Inactive DFGin ABAminus out-out in-in YJA Type1.5_Front
Xenopus laevis CAMK AURKBA AUKBA_XENLA Aurora kinase B-A 4C2VB 1.49 Inactive DFGin ABAminus out-out in-in YJA Type1.5_Front
Zea mays CMGC ACK2 CSK2A_MAIZE Casein kinase II subunit alpha 1M2PA 2.0 Active DFGin BLAminus in-in in-in HNA Type1
Zea mays CMGC ACK2 CSK2A_MAIZE Casein kinase II subunit alpha 1OM1A 1.68 Active DFGin BLAminus in-in in-in IQA Type1
Zea mays OTHER DRIK1 C0P4K9_MAIZE Protein kinase superfamily protein 6EASA 2.0 Inactive DFGout BBAminus out-none out-none J3A Type1