6E4F

BTK (Tyrosine-protein kinase BTK)
Group: TYR
Uniprot: BTK_HUMAN
Organism: Homo sapiens
Domain boundary: 402 - 653
Resolu: 1.15

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-out out-out HRA Type1.5_Back 389 - 658 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -        389        399        409 
mhhhhhhggg enlyfqgtaG LGYGSWEIDP KDLTFLKELG 
       419        429        439        449 
TGQFGVVKYG KWRGQYDVAI KMIKEGSMSE DEFIEEAKVM 
       459        469        479        489 
MNLSHEKLVQ LYGVCTKQRP IFIITEYMAN GCLLNYLREM 
       499        509        519        529 
RHRFQTQQLL EMCKDVCEAM EYLESKQFLH RDLAARNCLV 
       539        549        559        569 
NDQGVVKVSD FGLSRYVLDD EYTSSVGSKF PVRWSPPEVL 
       579        589        599        609 
MYSKFSSKSD IWAFGVLMWE IYSLGKMPYE RFTNSETAEH 
       619        629        639        649 
IAQGLRLYRP HLASEKVYTI MYSCWHEKAD ERPTFKILLS 
       659 
NILDVMDEEs
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None