Protein kinases in complex with 2TA (Fedratinib)

Total number of genes: 1
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin ABAminus 2 6VNEA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6VNEA 2.32 Inactive DFGin ABAminus in-in in-in 2TA Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6VNEB 2.32 Inactive DFGin ABAminus in-in in-out 2TA Type1

Protein kinases in complex with 2TA

Total number of genes: 1
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin ABAminus 2 6VNEA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6VNEA 2.32 Inactive DFGin ABAminus in-in in-in 2TA Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6VNEB 2.32 Inactive DFGin ABAminus in-in in-out 2TA Type1

Protein kinases in complex with 2TA

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type