4G3G

MAP3K14 (Mitogen-activated protein kinase kinase kinase 14)
Group: STE
Uniprot: M3K14_MOUSE
Organism: Mus musculus
Domain boundary: 402 - 657
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 0WA Type1 345 - 675 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -        348        358        368 
mhhhhhhgen lyfqgSGSVS SGQAHSLASL AKTWSsgsak 
       378        388        398        408 
lqrlGPETED NEGVLLTEKL KPVDYEYREE VHWMTHQPRL 
       418        428        438        448 
GRGSFGEVHR MKDKQTGFQC AVKKVRLEVF RVEELVACAG 
       458        468        478        488 
LSSPRIVPLY GAVREGPWVN IFMELLEGGS LGQLIKQMGC 
       498        508        518        528 
LPEDRALYYL GQALEGLEYL HTRRILHGDV KADNVLLSSD 
       538        548        558        568 
GSRAALCDFG HALCLqpdgl gkslltgDYI PGTETHMAPE 
       578        588        598        608 
VVMGKPCDAK VDIWSSCCMM LHMLNGCHPW TQYFRGPLCL 
       618        628        638        648 
KIASEPPPIR EIPPSCAPLT AQAIQEGLRK EPVHRASAME 
       658        668          - 
LRRKVGKALQ EVGGLKSPWK GEYKEPRGns
Lower-case residues are disordered in structure.
Mutations: V408L
Phosphorylation: None