3QGW

ITK (Tyrosine-protein kinase ITK/TSK)
Group: TYR
Uniprot: ITK_HUMAN
Organism: Homo sapiens
Domain boundary: 363 - 614
Resolu: 2.1

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAplus out-out none-out PQC Type1 358 - 618 17
B Inactive DFGin None in-out none-none L7A Type1 358 - 616 19
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -          -        364        374 
mgsshhhhhh ssglvprgsl hmvIDPSELT FVQEIGSGQF 
       384        394        404        414 
GLVHLGYWLN KDKVAIKTIK EGSMSEDDFI EEAEVMMKLS 
       424        434        444        454 
HPKLVQLYGV CLEQAPICLV FEFMEHGCLS DYLRTQRGLF 
       464        474        484        494 
AAETLLGMCL DVCEGMAYLE EACVIHRDLA ARNCLVGENQ 
       504        514        524        534 
VIKVSDFgmt rfvlddqyts stgtkfPVKW ASPEVFSFSR 
       544        554        564        574 
YSSKSDVWSF GVLMWEVFSE GKIPYENRSN SEVVEDISTG 
       584        594        604        614 
FRLYKPRLAS THVYQIMNHC WKERPEDRPA FSRLLRQLAE 

IAesgl
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None