4AQC

JAK2 (Tyrosine-protein kinase JAK2)
Group: TYR
Uniprot: JAK2_HUMAN
Organism: Homo sapiens
Domain boundary: 849 - 1124
Resolu: 1.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in 88A Type1 842 - 1132 0
B Inactive DFGin ABAminus in-in in-in 88A Type1 836 - 1132 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       841        851        861        871 
gamaFEDRDP TQFEERHLKF LQQLGKGNFG SVEMCRYDPL 
       881        891        901        911 
QDNTGEVVAV KKLQHSTEEH LRDFEREIEI LKSLQHDNIV 
       921        931        941        951 
KYKGVCYSAG RRNLKLIMEY LPYGSLRDYL QKHKERIDHI 
       961        971        981        991 
KLLQYTSQIC KGMEYLGTKR YIHRDLATRN ILVENENRVK 
      1001       1011       1021       1031 
IGDFGLTKVL PQDKEYYKVK EPGESPIFWY APESLTESKF 
      1041       1051       1061       1071 
SVASDVWSFG VVLYELFTYI EKSKSPPAEF MRMIGNDKQG 
      1081       1091       1101       1111 
QMIVFHLIEL LKNNGRLPRP DGCPDEIYMI MTECWNNNVN 
      1121       1131 
QRPSFRDLAL RVDQIRDNMA G
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1007,X1008