9CD7

FGFR3 (Fibroblast growth factor receptor 3)
Group: TYR
Uniprot: FGFR3_HUMAN
Organism: Homo sapiens
Domain boundary: 472 - 750
Resolu: 2.53

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAplus in-in none-out A1AV2 Type1 451 - 755 17
B Inactive DFGin BLAplus in-in out-out A1AV2 Type1 458 - 755 6
C Inactive DFGin BLAplus in-in out-out A1AV2 Type1 458 - 755 6
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain C
       457        467        477        487 
gptlanvsel ELPADPKWEL SRARLTLGKP LGEGAFGQVV 
       497        507        517        527 
MAEAIGIDKD RAAKPVTVAV KMLKDDATDK DLSDLVSEME 
       537        547        557        567 
MMKMIGKHKN IINLLGACTQ GGPLYVLVEY AAKGNLREFL 
       577        587        597        607 
RARRPPgldy sfdtskppee QLTFKDLVSC AYQVARGMEY 
       617        627        637        647 
LASQKCIHRD LAARNVLVTE DNVMKIADFG LARDVHNLDY 
       657        667        677        687 
YKettngrLP VKWMAPEALF DRVYTHQSDV WSFGVLLWEI 
       697        707        717        727 
FTLGGSPYPG IPVEELFKLL KEGHRMDKPA NCTHDLYMIM 
       737        747        757 
RECWHAAPSQ RPTFKQLVED LDRVLTVTst de
Lower-case residues are disordered in structure.
Mutations: C482A,C582S,K650E
Phosphorylation: None