PDB: 3QGW — TYR ITK_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 3QGWA
DFGin None 1 50.0% 3QGWB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR ITK ITK_HUMAN 3QGWA 2.1 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao PQC Type1 358 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3QGWB 2.1 Inactive DFGin‑None in-out none-none TYR APEdihe_nnnai APEdist_aaan L7A Type1 358 - 616 0 None None Tyrosine-protein kinase ITK/TSK

PDB: 3QGW — TYR ITK_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 3QGWA
DFGin None 1 50.0% 3QGWB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR ITK ITK_HUMAN 3QGWA 2.1 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao PQC Type1 358 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 3QGWB 2.1 Inactive DFGin‑None in-out none-none TYR APEdihe_nnnai APEdist_aaan L7A Type1 358 - 616 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens

PDB: 3QGW — TYR ITK_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism