Ligand: DRN

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 2V7OA
DFGin BLAplus 1 50.0% 4OTHA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC PKN1 PKN1_HUMAN 4OTHA 1.8 Inactive DFGin‑BLAplus in-in out-none nonTYR APEdihe_aannn APEdist_nnnn DRN Type1 606 - 940 0 TPO774,SEP916 None Serine/threonine-protein kinase N1
CAMK CAMK2G KCC2G_HUMAN 2V7OA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DRN Type1 3 - 302 0 SEP3 None Calcium/calmodulin-dependent protein kinase type II subunit gamma

Ligand: DRN

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 2V7OA
DFGin BLAplus 1 50.0% 4OTHA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC PKN1 PKN1_HUMAN 4OTHA 1.8 Inactive DFGin‑BLAplus in-in out-none nonTYR APEdihe_aannn APEdist_nnnn DRN Type1 606 - 940 0 TPO774,SEP916 None Serine/threonine-protein kinase N1 Homo sapiens
CAMK CAMK2G KCC2G_HUMAN 2V7OA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DRN Type1 3 - 302 0 SEP3 None Calcium/calmodulin-dependent protein kinase type II subunit gamma Homo sapiens

Ligand: DRN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism