Ligand

Protein kinases in complex with 6T2 (Crenolanib)

Total number of genes: 2

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	6BQPA
DFGin	BLAplus	1	6JOIA
None	None	1	6JOJA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
CAMK	CAMKK2	KKCC2_HUMAN	Calcium/calmodulin-dependent protein kinase kinase 2	6BQPA	1.95	Active	DFGin	BLAminus	in-in	in-in	6T2	Type1
TYR	PDGFRA	PGFRA_HUMAN	Platelet-derived growth factor receptor alpha	6JOIA	3.1	Inactive	DFGin	BLAplus	in-out	none-in	6T2	Type1
TYR	PDGFRA	PGFRA_HUMAN	Platelet-derived growth factor receptor alpha	6JOJA	2.6	Inactive	None	None	in-in	out-in	6T2	Type1

Protein kinases in complex with 6T2

Total number of genes: 2

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	6BQPA
DFGin	BLAplus	1	6JOIA
None	None	1	6JOJA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	CAMK	CAMKK2	KKCC2_HUMAN	Calcium/calmodulin-dependent protein kinase kinase 2	6BQPA	1.95	Active	DFGin	BLAminus	in-in	in-in	6T2	Type1
Homo sapiens	TYR	PDGFRA	PGFRA_HUMAN	Platelet-derived growth factor receptor alpha	6JOIA	3.1	Inactive	DFGin	BLAplus	in-out	none-in	6T2	Type1
Homo sapiens	TYR	PDGFRA	PGFRA_HUMAN	Platelet-derived growth factor receptor alpha	6JOJA	2.6	Inactive	None	None	in-in	out-in	6T2	Type1

Protein kinases in complex with 6T2

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type