All / BLBminus / All

Total number of chains: 292
Active chains: 0
Total number of genes: 47
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 292 100.0% 5NKGA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC ROCK1 ROCK1_HUMAN 7S26C 2.744 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 86K Type1 8 - 402 0 None None Rho-associated protein kinase 1
CAMK AURKA AURKA_HUMAN 8PR7D 2.76 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaoni APEdist_nnoo ADP ATPlike 126 - 388 0 None D274N,C290A,N332A,Q335A,T347A,D350A,C393A Aurora kinase A
CAMK DAPK1 DAPK1_HUMAN 3ZXTA 2.65 Inactive DFGin‑BLBminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 7 - 276 0 None None Death-associated protein kinase 1
CAMK MARK3 MARK3_HUMAN 7P1LA 1.95 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn V5E Type1 50 - 365 0 None None MAP/microtubule affinity-regulating kinase 3
CAMK MELK MELK_HUMAN 5IHCA 2.14 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 6BB Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase
CAMK MKNK2 MKNK2_HUMAN 8XFMA 2.6 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo A1LU6 Type1 73 - 372 0 None None MAP kinase-interacting serine/threonine-protein kinase 2
CAMK PIM1 PIM1_HUMAN 6KZIA 2.8 Inactive DFGin‑BLBminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RTX Type1 33 - 305 0 SEP261 None Serine/threonine-protein kinase pim-1
CAMK PLK2 PLK2_HUMAN 4I6HA 1.91 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaioo APEdist_iiio 1C8 Type1 71 - 355 0 None C83S,V87T,A119S,A216S,C259A,C291S,L335T Serine/threonine-protein kinase PLK2
CAMK PRKAA2 AAPK2_HUMAN 7MYJA 2.95 Inactive DFGin‑BLBminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4O7, ZQV Type1, Allosteric 7 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2
CAMK SNRK SNRK_HUMAN 5YKSA 2.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 1 - 344 0 None None SNF-related serine/threonine-protein kinase
CAMK SNRK SNRK_HUMAN 5YKSB 2.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 344 0 None None SNF-related serine/threonine-protein kinase
CMGC CDK2 CDK2_HUMAN 3PXFA 1.8 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 2AN, 2AN Allosteric, Type3 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3PXZA 1.7 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 2AN, 2AN, JWS Allosteric, Type3, Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 6YL6A 1.7 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 1 - 298 0 None F80C,C177A Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7UXIA 2.07 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nioo No_ligand No_ligand 2 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 5OO3A 1.73 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 9ZB Type1 2 - 294 0 None F80C,C177A Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 6YL1A 1.66 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nooo OWN Type1 1 - 298 0 None F80C,C177A Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 6YLKA 1.65 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo OY2 Type1 1 - 298 0 None F80C,C177A Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1DM2A 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno HMD Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1G5SA 2.61 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo I17 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1P2AA 2.5 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 5BN Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1PF8A 2.51 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oioo SU9 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2B52A 1.88 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_oooo D42 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2B55A 1.85 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno D31 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2BHEA 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno BRY Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2BHHA 2.6 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno RYU Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2BTSA 1.99 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno U32 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2C5YA 2.25 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo MTW Type1 1 - 297 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2FVDA 1.85 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_oooo LIA Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2J9MA 2.5 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno PY8 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2VTNA 2.2 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno LZ7 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2VTQA 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno LZA Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2VTTA 1.68 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno LZD Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2VU3A 1.85 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno LZE Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3TI1A 1.99 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo B49 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3TIZA 2.02 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3TI Type1 2 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3UNJA 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 0BX Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3UNKA 2.1 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 0BY Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 5ANGA 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo WY3 Type1 2 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7M2FA 1.632 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno YOS Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9D0UA 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo A1A1H Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8ERDA 1.33 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo WQ6 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 6INLA 1.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno AJR Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2R3NA 1.63 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo SCZ Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2VV9A 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo IM9 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2W17A 2.15 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo I19 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3SW7A 1.8 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo 19K Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4BZDA 1.83 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaiii APEdist_nnoo D6I Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4FKOA 1.55 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 20K Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3EZVA 1.99 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo EZV Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7RA5A 1.67 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 3I3 Type1 1 - 296 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8YNGA 1.82 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo A1D6S Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8YPWA 1.8 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo A1D6Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8YQEA 1.94 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo A1D60 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9JJ5A 1.71 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo A1EB0 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3PXYA 1.8 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo JWS Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3PY0A 1.75 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo SU9 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QQGA 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X06 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QQHA 1.87 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X0A Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QQKA 1.86 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X02 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QRTA 1.75 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X14 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QRUA 1.95 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo X19 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QTQA 1.8 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X35 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QTRA 1.85 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo X36 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QTUA 1.82 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo X44 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QTXA 1.95 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo X43 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QTZA 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X42 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QWKA 1.85 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X62 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3QXPA 1.75 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X64 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3R8MA 1.8 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo Z19 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3R8ZA 1.85 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo Z63 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3RAKA 1.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 03Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3RALA 1.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 04Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3RJCA 1.85 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 06Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3RK9A 1.85 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 09Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3RMFA 1.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 20Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3RNIA 1.95 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 21Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3RPVA 1.8 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 26Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3RPYA 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo 27Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3S1HA 1.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 56Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3SQQA 1.85 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 99Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4ERWA 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo STU Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4EZ3A 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 0S0 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4GCJA 1.42 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo X64 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 6GUHA 1.5 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_oooo FB8 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4D1ZA 1.851 Inactive DFGin‑BLBminus out-none none-none nonTYR APEdihe_aanii APEdist_nnnn WG8, WG8 Type1, Allosteric 3 - 295 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 5FP5A 2.16 Inactive DFGin‑BLBminus out-none none-none nonTYR APEdihe_aanii APEdist_nnnn 1Y6, 1Y6 Type1, Allosteric 1 - 295 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 5FP6A 1.85 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno MFZ, MFZ Type1, Allosteric 1 - 294 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3PXQA 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo 2AN, 2AN, 2AN Type1, Allosteric, Type3 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3PY1A 2.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo SU9, 2AN, 2AN Type1, Allosteric, Type3 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7RWEA 1.59 Inactive DFGin‑BLBminus none-none none-out nonTYR APEdihe_aanoi APEdist_nnnn 7TH, 7TH Type1, Type3 3 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7SA0A 1.59 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8KQ, 8KQ Type1, Type3 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8FOWA 1.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nooo 1QK, 7TW Type1, Type3 3 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8FP0A 1.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo RRC, 7TW Type1, Type3 2 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4EZ7A 2.49 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo STU, 2AN, 2AN Type1, Type3, Allosteric 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7RXOA 1.38 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaiii APEdist_nnoo 80E Type3 3 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7S4TA 1.91 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 88O Type3 3 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7S7AA 1.7 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaiii APEdist_nnoo 8FI Type3 2 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7S84A 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8IL Type3 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7S85A 1.98 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8IQ Type3 3 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7S9XA 1.69 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8KF Type3 3 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7RWFA 1.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 7TW Type3 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7UG1A 1.84 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nooo N5R, N5R Type3, Allosteric 1 - 295 0 None None Cyclin-dependent kinase 2
CMGC CDK8 CDK8_HUMAN 4G6LA 2.7 Inactive DFGin‑BLBminus in-in out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 5FGKA 2.36 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 5XG Type1 1 - 362 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 5HBEA 2.38 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 5Y6 Type1 1 - 361 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 5HNBA 2.35 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanio APEdist_nnnn 62M Type1 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 5I5ZA 2.6 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 68U Type1 1 - 362 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 5IDPA 2.65 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 6A6 Type1 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 4F7SA 2.2 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 0SW Type1 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 5BNJA 2.64 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 4TV Type1 1 - 362 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 6QTGA 2.7 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno JH8 Type1 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 4CRLA 2.4 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno C1I Type1 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 5CEIA 2.24 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 50R Type1 1 - 362 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 6R3SA 2.19 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn JRE Type1 1 - 362 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 6Y0AA 2.19 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn JRE Type1 1 - 362 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 6T41A 2.45 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn MFE Type1 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDKL2 CDKL2_HUMAN 4AAAA 1.53 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaiii APEdist_nooo DKI Type1 1 - 302 0 None T159D,Y161E Cyclin-dependent kinase-like 2
CMGC CDKL2 CDKL2_HUMAN 8S6IA 1.72 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo A1H5G Type1 1 - 305 0 None None Cyclin-dependent kinase-like 2
CMGC MAPK14 MK14_HUMAN 5N68A 1.85 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 8OK Allosteric 4 - 351 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 8YD9A 1.66 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 6GI Allosteric 4 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2Y8OA 1.95 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 4 - 353 0 None C162S Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1R3CA 2.0 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 4 - 352 0 None C162S Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2LGCA 999.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 2 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5ETAA 2.8 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5ETAB 2.8 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 9CJ2B 2.83 Inactive DFGin‑BLBminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 352 0 TPO180,PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1R39A 2.3 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 4 - 351 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2OKRA 2.0 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2OKRD 2.0 Inactive DFGin‑BLBminus in-in out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 5 - 355 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2ONLA 4.0 Inactive DFGin‑BLBminus in-in out-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2ONLB 4.0 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5ETFA 2.4 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 4 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1BMKA 2.4 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaooi APEdist_oooo SB5 Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3MW1A 2.8 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo MIH Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1DI9A 2.6 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo MSQ Type1 4 - 351 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1W7HA 2.214 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 3IP Type1 4 - 355 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1W84A 2.2 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo L12 Type1 4 - 355 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2ZB0A 2.1 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo GK3 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1M7QA 2.4 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo DQO Type1 4 - 351 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1OUKA 2.5 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 084 Type1 4 - 351 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1OUYA 2.5 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 094 Type1 4 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1YQJA 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaooi APEdist_oooo 6NP Type1 2 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3ZYAA 1.9 Inactive DFGin‑BLBminus out-in none-out nonTYR APEdihe_aaooi APEdist_nnno 2A8 Type1 1 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1OZ1A 2.1 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo FPH Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FLQA 1.9 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 891 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FMJA 2.0 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno FMJ Type1 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3FSFA 2.1 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno FSS Type1 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1A9UA 2.5 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SB2 Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1BL6A 2.5 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SB6 Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1BL7A 2.5 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SB4 Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3MPAA 2.1 Inactive DFGin‑BLBminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn SB2 Type1 5 - 352 0 None D168G Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2ZB1A 2.5 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo GK4 Type1.5_Back 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5XYXA 2.61 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno FTZ Type1.5_Back 4 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5XYYA 1.7 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo P0F Type1.5_Back 4 - 352 0 None None Mitogen-activated protein kinase 14
NEK NEK2 NEK2_HUMAN 5M53A 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 7GJ Type1 7 - 271 0 None None Serine/threonine-protein kinase Nek2
OTHER IKBKB IKKB_HUMAN 8OMVB 4.16 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaiio APEdist_nnoo No_ligand No_ligand 8 - 664 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta
OTHER MLKL MLKL_HUMAN 4MWIA 1.7 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo PXN Allosteric 193 - 470 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 6BWKA 2.79 Pseudo DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 192 - 470 0 None T357E,S358E Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 7JW7A 2.63 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 8SLZA 2.3 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 469 0 TPO357,SEP358 None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 4M67A 1.9 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 469 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 6LK6A 2.41 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357A,S358A Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 6LK5A 2.5 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357E,S358D Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 5KO1A 2.16 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo 6UY Type1 192 - 470 0 None E366A,K367A Mixed lineage kinase domain-like protein
OTHER PAN3 PAN3_HUMAN 9QTUA 4.6 Pseudo DFGin‑BLBminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 887 0 None None PAN2-PAN3 deadenylation complex subunit PAN3
OTHER PAN3 PAN3_HUMAN 9QTUB 4.6 Pseudo DFGin‑BLBminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 887 0 None None PAN2-PAN3 deadenylation complex subunit PAN3
OTHER PIK3R4 PI3R4_HUMAN 8SORA 3.96 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo ADP ATPlike 15 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 9MHFA 2.73 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 14 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 9MHGA 3.2 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 2 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 A0JP11_HUMAN 9ZPCA 3.83 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 40 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER WNK3 WNK3_HUMAN 5O1VA 1.723 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 134 - 412 0 SEP304 None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O1VB 1.723 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 134 - 410 0 SEP304 None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O2CA 2.4 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 129 - 496 0 None None Serine/threonine-protein kinase WNK3
OTHER WNK3 WNK3_HUMAN 5O2BB 2.038 Inactive DFGin‑BLBminus out-na out-none nonTYR APEdihe_aanii APEdist_nnnn KS1 Type1 135 - 406 0 None None Serine/threonine-protein kinase WNK3
STE MAP2K1 MP2K1_HUMAN 8CHFE 4.25 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo No_ligand No_ligand 62 - 379 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 8CHFF 4.25 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo No_ligand No_ligand 62 - 379 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE PAK1 PAK1_HUMAN 9D4XB 1.847 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2S Type1 256 - 543 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 9D4YB 1.847 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2S Type1 256 - 543 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
STE STK10 STK10_HUMAN 7QGPA 1.9 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaiio APEdist_iioo DJ8 Type1.5_Front 23 - 313 0 None None Serine/threonine-protein kinase 10
STE STK24 STK24_HUMAN 3ZHPC 2.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 31 - 300 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 3ZHPD 2.9 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaiii APEdist_nooo No_ligand No_ligand 32 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 8BZIA 1.72 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SJL Type1.5_Back 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 8BZJA 2.52 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SJX Type1.5_Back 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 7B30A 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 59T Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 7B31A 1.8 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SQ8 Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 7B32A 1.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SQQ Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 7B33A 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SQE Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 7B34A 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SQK Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 7B35A 2.4 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SQB Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 7B35B 2.4 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SQB Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 8BZJB 2.52 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn SJX Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 8QLRA 1.85 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn VYN Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 8QLRB 1.85 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn VYN Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 8QLSA 1.61 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn VYH Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24
STE STK24 STK24_HUMAN 8QLTA 1.47 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn VZ2 Type1.5_Front 25 - 301 0 None None Serine/threonine-protein kinase 24
STE STK26 STK26_HUMAN 7B36C 2.107 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 59T Type1.5_Back 17 - 299 0 None None Serine/threonine-protein kinase 26
STE STK26 STK26_HUMAN 7B36A 2.107 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 59T Type1.5_Front 18 - 300 0 None None Serine/threonine-protein kinase 26
STE STK3 STK3_HUMAN 4LGDA 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 16 - 488 0 None D146N Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LGDB 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 10 - 488 0 None D146N Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LGDC 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 12 - 490 0 None D146N Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LGDD 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 11 - 489 0 None D146N Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4A 2.42 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 18 - 308 0 None D146N Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4B 2.42 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 18 - 308 0 None D146N Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4C 2.42 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 18 - 307 0 None D146N Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4E 2.42 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 18 - 308 0 None D146N Serine/threonine-protein kinase 3
STE STK4 STK4_HUMAN 9IICA 2.78 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 11 - 308 0 None K59R Serine/threonine-protein kinase 4
STE STK4 STK4_HUMAN 9IICB 2.78 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 11 - 311 0 None K59R Serine/threonine-protein kinase 4
TKL BRAF BRAF_HUMAN 3SKCA 3.2 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno BR2 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4E26B 2.55 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaoii APEdist_nnoo 734 Type1 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIEA 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIEB 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIEC 3.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIED 3.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7P3VA 2.37 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 5I4 Type1.5_Back 448 - 719 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7P3VB 2.37 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 5I4 Type1.5_Back 448 - 719 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4CQEB 2.3 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno CQE Type1.5_Back 448 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV2A 2.5 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P06 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV2B 2.5 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno P06 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5CSWB 2.66 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn P06 Type1.5_Back 447 - 721 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6V2UB 3.78 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn P06 Type1.5_Back 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL IRAK4 IRAK4_HUMAN 2NRYA 2.15 Inactive DFGin‑BLBminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 458 0 TPO345 None Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2NRYB 2.15 Inactive DFGin‑BLBminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 458 0 TPO345 None Interleukin-1 receptor-associated kinase 4
TKL MAP3K12 M3K12_HUMAN 5CENA 1.7 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaooi APEdist_iioo No_ligand No_ligand 117 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K7 M3K7_HUMAN 2EVAA 2.0 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno ADN Type1 31 - 305 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 4GS6A 2.2 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 1FM Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 4L3PA 2.68 Inactive DFGin‑BLBminus in-in none-none nonTYR APEdihe_aaiii APEdist_nnni 1UH Type1 31 - 497 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5JGBA 2.8 Inactive DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaoii APEdist_nnno 6JV Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL RAF1 RAF1_HUMAN 9O0UC 2.91 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo 324 Type1 339 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9O0VC 3.5 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo 324 Type1 339 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RIPK2 RIPK2_HUMAN 6S1FA 3.11 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6S1FC 3.11 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR8B 2.79 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo XYW Type1.5_Back 8 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TYR EGFR EGFR_HUMAN 7JXIC 3.0 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RJ6A 2.7 Inactive DFGin‑BLBminus in-in in-none TYR APEdihe_nniai APEdist_aaai 3R0 Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5EM6A 2.78 Inactive DFGin‑BLBminus in-in in-none TYR APEdihe_nniai APEdist_aaai 5Q3 Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A2DA 1.11 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nniai APEdist_aaai KXY Type3 701 - 1021 0 None L858R,V948R Epidermal growth factor receptor
TYR EPHA2 EPHA2_HUMAN 5I9WA 1.359 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 605 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJCA 2.3 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_niiai APEdist_aaai ACP ATPlike 590 - 976 0 None S901E Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJCB 2.3 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ACP ATPlike 590 - 965 0 None S901E Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 7KJAA 1.75 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ACP ATPlike 590 - 976 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5I9XA 1.427 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DB8 Type1 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5I9YA 1.228 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_nnnai APEdist_aaan 1N1 Type1 600 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5I9ZA 1.698 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_nniai APEdist_aaai 627 Type1 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA0B 1.948 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_nniai APEdist_aaai A5B Type1 600 - 882 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA0C 1.948 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan A5B Type1 600 - 890 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA3A 1.788 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_nniai APEdist_aaai P17 Type1 602 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NJZA 1.768 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nniai APEdist_aaai 8ZH Type1 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK1A 1.548 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 90N Type1 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK2A 1.649 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 8ZZ Type1 598 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK4A 1.45 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 90E Type1 601 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK5A 1.329 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 90K Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK6A 1.267 Inactive DFGin‑BLBminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 90W Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK7A 1.889 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 8ZZ Type1 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NK9A 1.588 Inactive DFGin‑BLBminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 912 Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKBA 1.5 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 8ZT Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKCA 1.448 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_niiai APEdist_aaai 90T Type1 601 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKDA 1.408 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 91K Type1 600 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKEA 1.39 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 90B Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKFA 1.099 Inactive DFGin‑BLBminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 8ZN Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKGA 1.1 Inactive DFGin‑BLBminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 8ZK Type1 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKHA 1.29 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 8ZQ Type1 601 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5NKIA 1.675 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 8ZW Type1 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BK0A 1.7 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_nniai APEdist_aaai QJI Type1 605 - 887 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 5IA2A 1.619 Inactive DFGin‑BLBminus in-out out-in TYR APEdihe_iiiai APEdist_aaai L66 Type1.5_Back 598 - 888 0 None None Ephrin type-A receptor 2
TYR EPHA7 EPHA7_HUMAN 7EEFA 2.6 Inactive DFGin‑BLBminus in-in none-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 606 - 899 0 None G656E Ephrin type-A receptor 7
TYR EPHB4 EPHB4_HUMAN 6FNKA 1.049 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DXK Type1 604 - 889 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 6FNMA 1.157 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1 608 - 889 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 4AW5A 2.33 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nniai APEdist_aaai 30K Type1 607 - 888 0 None None Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VWXA 1.65 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7X4 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VWYA 1.65 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7X5 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VWZA 1.65 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7X6 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VX0A 2.1 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7X7 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2VX1A 1.65 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7X8 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2X9FA 1.75 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai X9F Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 4BB4A 1.65 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 32W Type1 606 - 888 0 None Y774E Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 2XVDA 1.7 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AS6 Type1.5_Back 607 - 888 0 None Y774E Ephrin type-B receptor 4
TYR ERBB2 ERBB2_HUMAN 7PCDA 1.77 Inactive DFGin‑BLBminus out-out out-none TYR APEdihe_nniai APEdist_aaai 70I Type1.5_Back 710 - 991 0 None None Receptor tyrosine-protein kinase erbB-2
TYR ERBB2 ERBB2_HUMAN 7JXHA 3.27 Inactive DFGin‑BLBminus out-out out-out TYR APEdihe_nniai APEdist_aaao VOY Type1.5_Back 706 - 992 0 None None Receptor tyrosine-protein kinase erbB-2
TYR FGFR1 FGFR1_HUMAN 3KXXA 3.2 Inactive DFGin‑BLBminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 461 - 765 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1
TYR FGFR2 FGFR2_HUMAN 6V6QC 2.46 Inactive DFGin‑BLBminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 766 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2
TYR IGF1R IGF1R_HUMAN 3QQUA 2.9 Inactive DFGin‑BLBminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 01P Type1 991 - 1285 0 None None Insulin-like growth factor 1 receptor
TYR LCK LCK_HUMAN 3B2WA 2.3 Inactive DFGin‑BLBminus in-in out-out TYR APEdihe_oiiai APEdist_aaai 9NH Type1 238 - 500 0 None None Tyrosine-protein kinase Lck
TYR MERTK MERTK_HUMAN 7AVYA 2.31 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S4E Type1 576 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AW2A 2.1 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S4W Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7OLSA 1.89 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan VJZ Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7OLVA 2.13 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan VK2 Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7OLXA 1.98 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan VK5 Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MET MET_HUMAN 3Q6UA 1.6 Inactive DFGin‑BLBminus in-out none-none TYR APEdihe_nniai APEdist_aaai AME Allosteric 1048 - 1348 0 None None Hepatocyte growth factor receptor
TYR PDGFRA A0A0B4J203_HUMAN 8XRRA 2.57 Inactive DFGin‑BLBminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1LV8 Type1 338 - 730 0 None None receptor protein-tyrosine kinase
TYR PTK2 FAK1_HUMAN 2IJMB 2.187 Inactive DFGin‑BLBminus in-out none-out TYR APEdihe_nnoai APEdist_aaao ADP ATPlike 414 - 689 0 None None Focal adhesion kinase 1
TYR SRC SRC_HUMAN 1FMKA 1.5 Inactive DFGin‑BLBminus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 86 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src

All / BLBminus / All

Total number of chains: 447
Active chains: 0
Total number of genes: 64
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 447 100.0% 5NKGA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK CIPK23 CIPKN_ARATH 4CZTA 2.3 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo CPS Type1 25 - 315 0 None None CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZTB 2.3 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo CPS Type1 25 - 313 0 None None CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZUA 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo CPS Type1 25 - 320 0 None T190D CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZTC 2.3 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo CPS, CPS Type1, Allosteric 28 - 313 0 None None CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZUB 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo CPS, CPS Type1, Allosteric 25 - 313 0 None T190D CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZUC 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo CPS, CPS Type1, Allosteric 27 - 312 0 None T190D CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZUD 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo CPS, CPS Type1, Allosteric 25 - 324 0 None T190D CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZTD 2.3 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo CPS, CPS, CPS Type1, Allosteric, Allosteric 25 - 324 0 None None CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK24 CIPKO_ARATH 4D28C 3.3 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 7 - 289 0 None P81K,E107K,S109D,C127S,T168D,S228D,L266K CBL-interacting serine/threonine-protein kinase 24 Arabidopsis thaliana
CMGC MPK6 MPK6_ARATH 5CI6A 3.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaiii APEdist_nnno No_ligand No_ligand 32 - 393 0 None None Mitogen-activated protein kinase 6 Arabidopsis thaliana
OTHER BIR2 BIR2_ARATH 4L68A 2.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiai APEdist_nioi PDO Allosteric 272 - 600 0 None None Inactive LRR receptor-like serine/threonine-protein kinase BIR2 Arabidopsis thaliana
OTHER BIR2 BIR2_ARATH 4L68B 2.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 271 - 600 0 None None Inactive LRR receptor-like serine/threonine-protein kinase BIR2 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTVA 2.886 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 639 0 None D489A Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTVB 2.886 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 640 0 None D489A Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
OTHER STKLD1 F1MSZ0_BOVIN 9FQRXR 5.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoai APEdist_oooo No_ligand No_ligand 1 - 610 0 None None Serine/threonine kinase like domain containing 1 Bos taurus
TKL ROCO4 ROCO4_DICDI 4F0GA 2.0 Inactive DFGin‑BLBminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
OTHER MLKL F6S337_HORSE 6VC0A 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 536 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER MLKL F6S337_HORSE 6VC0B 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 258 - 537 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER MLKL F6S337_HORSE 6VC0C 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 541 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
TYR SRC SRC_CHICK 3U51A 2.241 Inactive DFGin‑BLBminus out-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 261 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3U51B 2.241 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 261 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3SVVA 2.204 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_nnnai APEdist_aaan VSP Type1.5_Back 257 - 533 0 None T338C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3SVVB 2.204 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan VSP Type1.5_Back 256 - 533 0 None T338C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4DGGA 2.65 Inactive DFGin‑BLBminus out-none none-out TYR APEdihe_nniai APEdist_aaao I76 Type1.5_Front 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5J5SA 2.153 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan 6G3 Type1.5_Front 258 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5J5SB 2.153 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan 6G3 Type1.5_Front 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
CMGC CDK A8BZ95_GIAIC 3GC0A 2.0 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaoni APEdist_nooo AMP ATPlike 11 - 308 0 None None cyclin-dependent kinase Giardia intestinalis
CMGC CDK A8BZ95_GIAIC 3GBZA 1.85 Inactive DFGin‑BLBminus out-none out-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 11 - 308 0 None None cyclin-dependent kinase Giardia intestinalis
AGC ROCK1 ROCK1_HUMAN 7S26C 2.744 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 86K Type1 8 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
CAMK AURKA AURKA_HUMAN 8PR7D 2.76 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaoni APEdist_nnoo ADP ATPlike 126 - 388 0 None D274N,C290A,N332A,Q335A,T347A,D350A,C393A Aurora kinase A Homo sapiens
CAMK DAPK1 DAPK1_HUMAN 3ZXTA 2.65 Inactive DFGin‑BLBminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn ACP ATPlike 7 - 276 0 None None Death-associated protein kinase 1 Homo sapiens
CAMK MARK3 MARK3_HUMAN 7P1LA 1.95 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn V5E Type1 50 - 365 0 None None MAP/microtubule affinity-regulating kinase 3 Homo sapiens
CAMK MELK MELK_HUMAN 5IHCA 2.14 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 6BB Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MKNK2 MKNK2_HUMAN 8XFMA 2.6 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo A1LU6 Type1 73 - 372 0 None None MAP kinase-interacting serine/threonine-protein kinase 2 Homo sapiens
CAMK PIM1 PIM1_HUMAN 6KZIA 2.8 Inactive DFGin‑BLBminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RTX Type1 33 - 305 0 SEP261 None Serine/threonine-protein kinase pim-1 Homo sapiens
CAMK PLK2 PLK2_HUMAN 4I6HA 1.91 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaioo APEdist_iiio 1C8 Type1 71 - 355 0 None C83S,V87T,A119S,A216S,C259A,C291S,L335T Serine/threonine-protein kinase PLK2 Homo sapiens
CAMK PRKAA2 AAPK2_HUMAN 7MYJA 2.95 Inactive DFGin‑BLBminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4O7, ZQV Type1, Allosteric 7 - 551 0 TPO172 None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
CAMK SNRK SNRK_HUMAN 5YKSA 2.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 1 - 344 0 None None SNF-related serine/threonine-protein kinase Homo sapiens
CAMK SNRK SNRK_HUMAN 5YKSB 2.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 1 - 344 0 None None SNF-related serine/threonine-protein kinase Homo sapiens
CMGC CDK2 CDK2_HUMAN 3PXFA 1.8 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 2AN, 2AN Allosteric, Type3 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3PXZA 1.7 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 2AN, 2AN, JWS Allosteric, Type3, Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 6YL6A 1.7 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 1 - 298 0 None F80C,C177A Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7UXIA 2.07 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nioo No_ligand No_ligand 2 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 5OO3A 1.73 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 9ZB Type1 2 - 294 0 None F80C,C177A Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 6YL1A 1.66 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nooo OWN Type1 1 - 298 0 None F80C,C177A Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 6YLKA 1.65 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo OY2 Type1 1 - 298 0 None F80C,C177A Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1DM2A 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno HMD Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1G5SA 2.61 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo I17 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1P2AA 2.5 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno 5BN Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 1PF8A 2.51 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oioo SU9 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2B52A 1.88 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_oooo D42 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2B55A 1.85 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno D31 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2BHEA 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno BRY Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2BHHA 2.6 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno RYU Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2BTSA 1.99 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno U32 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2C5YA 2.25 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo MTW Type1 1 - 297 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2FVDA 1.85 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_oooo LIA Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2J9MA 2.5 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno PY8 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2VTNA 2.2 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno LZ7 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2VTQA 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno LZA Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2VTTA 1.68 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno LZD Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2VU3A 1.85 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno LZE Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3TI1A 1.99 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo B49 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3TIZA 2.02 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 3TI Type1 2 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3UNJA 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 0BX Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3UNKA 2.1 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 0BY Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 5ANGA 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo WY3 Type1 2 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7M2FA 1.632 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno YOS Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 9D0UA 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo A1A1H Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 8ERDA 1.33 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo WQ6 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 6INLA 1.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno AJR Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2R3NA 1.63 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo SCZ Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2VV9A 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo IM9 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 2W17A 2.15 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo I19 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3SW7A 1.8 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo 19K Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4BZDA 1.83 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaiii APEdist_nnoo D6I Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4FKOA 1.55 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 20K Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3EZVA 1.99 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo EZV Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7RA5A 1.67 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 3I3 Type1 1 - 296 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 8YNGA 1.82 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo A1D6S Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 8YPWA 1.8 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo A1D6Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 8YQEA 1.94 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo A1D60 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 9JJ5A 1.71 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo A1EB0 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3PXYA 1.8 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo JWS Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3PY0A 1.75 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo SU9 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QQGA 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X06 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QQHA 1.87 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X0A Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QQKA 1.86 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X02 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QRTA 1.75 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X14 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QRUA 1.95 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo X19 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QTQA 1.8 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X35 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QTRA 1.85 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo X36 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QTUA 1.82 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo X44 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QTXA 1.95 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo X43 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QTZA 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X42 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QWKA 1.85 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X62 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3QXPA 1.75 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X64 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3R8MA 1.8 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_nooo Z19 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3R8ZA 1.85 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo Z63 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3RAKA 1.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 03Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3RALA 1.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 04Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3RJCA 1.85 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 06Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3RK9A 1.85 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 09Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3RMFA 1.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 20Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3RNIA 1.95 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 21Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3RPVA 1.8 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo 26Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3RPYA 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo 27Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3S1HA 1.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 56Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3SQQA 1.85 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 99Z Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4ERWA 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo STU Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4EZ3A 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 0S0 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4GCJA 1.42 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo X64 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 6GUHA 1.5 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_oooo FB8 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4D1ZA 1.851 Inactive DFGin‑BLBminus out-none none-none nonTYR APEdihe_aanii APEdist_nnnn WG8, WG8 Type1, Allosteric 3 - 295 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 5FP5A 2.16 Inactive DFGin‑BLBminus out-none none-none nonTYR APEdihe_aanii APEdist_nnnn 1Y6, 1Y6 Type1, Allosteric 1 - 295 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 5FP6A 1.85 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnno MFZ, MFZ Type1, Allosteric 1 - 294 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3PXQA 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo 2AN, 2AN, 2AN Type1, Allosteric, Type3 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3PY1A 2.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_iooo SU9, 2AN, 2AN Type1, Allosteric, Type3 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7RWEA 1.59 Inactive DFGin‑BLBminus none-none none-out nonTYR APEdihe_aanoi APEdist_nnnn 7TH, 7TH Type1, Type3 3 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7SA0A 1.59 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8KQ, 8KQ Type1, Type3 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 8FOWA 1.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nooo 1QK, 7TW Type1, Type3 3 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 8FP0A 1.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo RRC, 7TW Type1, Type3 2 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 4EZ7A 2.49 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo STU, 2AN, 2AN Type1, Type3, Allosteric 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7RXOA 1.38 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaiii APEdist_nnoo 80E Type3 3 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7S4TA 1.91 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 88O Type3 3 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7S7AA 1.7 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaiii APEdist_nnoo 8FI Type3 2 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7S84A 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8IL Type3 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7S85A 1.98 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8IQ Type3 3 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7S9XA 1.69 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8KF Type3 3 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7RWFA 1.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 7TW Type3 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7UG1A 1.84 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nooo N5R, N5R Type3, Allosteric 1 - 295 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK8 CDK8_HUMAN 4G6LA 2.7 Inactive DFGin‑BLBminus in-in out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 5FGKA 2.36 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 5XG Type1 1 - 362 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 5HBEA 2.38 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 5Y6 Type1 1 - 361 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 5HNBA 2.35 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanio APEdist_nnnn 62M Type1 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 5I5ZA 2.6 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 68U Type1 1 - 362 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 5IDPA 2.65 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 6A6 Type1 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 4F7SA 2.2 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 0SW Type1 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 5BNJA 2.64 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 4TV Type1 1 - 362 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 6QTGA 2.7 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno JH8 Type1 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 4CRLA 2.4 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno C1I Type1 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 5CEIA 2.24 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 50R Type1 1 - 362 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 6R3SA 2.19 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn JRE Type1 1 - 362 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 6Y0AA 2.19 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn JRE Type1 1 - 362 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 6T41A 2.45 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn MFE Type1 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDKL2 CDKL2_HUMAN 4AAAA 1.53 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaiii APEdist_nooo DKI Type1 1 - 302 0 None T159D,Y161E Cyclin-dependent kinase-like 2 Homo sapiens
CMGC CDKL2 CDKL2_HUMAN 8S6IA 1.72 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnoo A1H5G Type1 1 - 305 0 None None Cyclin-dependent kinase-like 2 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5N68A 1.85 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 8OK Allosteric 4 - 351 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 8YD9A 1.66 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 6GI Allosteric 4 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2Y8OA 1.95 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 4 - 353 0 None C162S Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1R3CA 2.0 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 4 - 352 0 None C162S Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2LGCA 999.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 2 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5ETAA 2.8 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5ETAB 2.8 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 4 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 9CJ2B 2.83 Inactive DFGin‑BLBminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 352 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1R39A 2.3 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 4 - 351 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2OKRA 2.0 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2OKRD 2.0 Inactive DFGin‑BLBminus in-in out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 5 - 355 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2ONLA 4.0 Inactive DFGin‑BLBminus in-in out-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2ONLB 4.0 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5ETFA 2.4 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 4 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1BMKA 2.4 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaooi APEdist_oooo SB5 Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3MW1A 2.8 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo MIH Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1DI9A 2.6 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo MSQ Type1 4 - 351 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1W7HA 2.214 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 3IP Type1 4 - 355 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1W84A 2.2 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo L12 Type1 4 - 355 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2ZB0A 2.1 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo GK3 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1M7QA 2.4 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo DQO Type1 4 - 351 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1OUKA 2.5 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 084 Type1 4 - 351 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1OUYA 2.5 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 094 Type1 4 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1YQJA 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaooi APEdist_oooo 6NP Type1 2 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3ZYAA 1.9 Inactive DFGin‑BLBminus out-in none-out nonTYR APEdihe_aaooi APEdist_nnno 2A8 Type1 1 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1OZ1A 2.1 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo FPH Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FLQA 1.9 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 891 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FMJA 2.0 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno FMJ Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3FSFA 2.1 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno FSS Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1A9UA 2.5 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SB2 Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1BL6A 2.5 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SB6 Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1BL7A 2.5 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SB4 Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3MPAA 2.1 Inactive DFGin‑BLBminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn SB2 Type1 5 - 352 0 None D168G Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2ZB1A 2.5 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo GK4 Type1.5_Back 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5XYXA 2.61 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno FTZ Type1.5_Back 4 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5XYYA 1.7 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo P0F Type1.5_Back 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
NEK NEK2 NEK2_HUMAN 5M53A 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 7GJ Type1 7 - 271 0 None None Serine/threonine-protein kinase Nek2 Homo sapiens
OTHER IKBKB IKKB_HUMAN 8OMVB 4.16 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaiio APEdist_nnoo No_ligand No_ligand 8 - 664 0 None S177E,S181E Inhibitor of nuclear factor kappa-B kinase subunit beta Homo sapiens
OTHER MLKL MLKL_HUMAN 4MWIA 1.7 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo PXN Allosteric 193 - 470 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 6BWKA 2.79 Pseudo DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 192 - 470 0 None T357E,S358E Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 7JW7A 2.63 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 8SLZA 2.3 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 469 0 TPO357,SEP358 None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 4M67A 1.9 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 469 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 6LK6A 2.41 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357A,S358A Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 6LK5A 2.5 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357E,S358D Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 5KO1A 2.16 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo 6UY Type1 192 - 470 0 None E366A,K367A Mixed lineage kinase domain-like protein Homo sapiens
OTHER PAN3 PAN3_HUMAN 9QTUA 4.6 Pseudo DFGin‑BLBminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 887 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Homo sapiens
OTHER PAN3 PAN3_HUMAN 9QTUB 4.6 Pseudo DFGin‑BLBminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 887 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 8SORA 3.96 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo ADP ATPlike 15 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 9MHFA 2.73 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 14 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 9MHGA 3.2 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 2 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 A0JP11_HUMAN 9ZPCA 3.83 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 40 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O1VA 1.723 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 134 - 412 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O1VB 1.723 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 134 - 410 0 SEP304 None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O2CA 2.4 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiii APEdist_oioi No_ligand No_ligand 129 - 496 0 None None Serine/threonine-protein kinase WNK3 Homo sapiens
OTHER WNK3 WNK3_HUMAN 5O2BB 2.038 Inactive DFGin‑BLBminus out-na out-none nonTYR APEdihe_aanii APEdist_nnnn KS1 Type1 135 - 406 0 None None Serine/threonine-protein kinase WNK3 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 8CHFE 4.25 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo No_ligand No_ligand 62 - 379 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 8CHFF 4.25 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo No_ligand No_ligand 62 - 379 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE PAK1 PAK1_HUMAN 9D4XB 1.847 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2S Type1 256 - 543 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 9D4YB 1.847 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2S Type1 256 - 543 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
STE STK10 STK10_HUMAN 7QGPA 1.9 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaiio APEdist_iioo DJ8 Type1.5_Front 23 - 313 0 None None Serine/threonine-protein kinase 10 Homo sapiens
STE STK24 STK24_HUMAN 3ZHPC 2.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 31 - 300 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 3ZHPD 2.9 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaiii APEdist_nooo No_ligand No_ligand 32 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 8BZIA 1.72 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SJL Type1.5_Back 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 8BZJA 2.52 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SJX Type1.5_Back 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 7B30A 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 59T Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 7B31A 1.8 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SQ8 Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 7B32A 1.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SQQ Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 7B33A 1.9 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SQE Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 7B34A 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SQK Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 7B35A 2.4 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SQB Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 7B35B 2.4 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn SQB Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 8BZJB 2.52 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn SJX Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 8QLRA 1.85 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn VYN Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 8QLRB 1.85 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn VYN Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 8QLSA 1.61 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn VYH Type1.5_Front 26 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK24 STK24_HUMAN 8QLTA 1.47 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn VZ2 Type1.5_Front 25 - 301 0 None None Serine/threonine-protein kinase 24 Homo sapiens
STE STK26 STK26_HUMAN 7B36C 2.107 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo 59T Type1.5_Back 17 - 299 0 None None Serine/threonine-protein kinase 26 Homo sapiens
STE STK26 STK26_HUMAN 7B36A 2.107 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 59T Type1.5_Front 18 - 300 0 None None Serine/threonine-protein kinase 26 Homo sapiens
STE STK3 STK3_HUMAN 4LGDA 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 16 - 488 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STK3 STK3_HUMAN 4LGDB 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 10 - 488 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STK3 STK3_HUMAN 4LGDC 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 12 - 490 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STK3 STK3_HUMAN 4LGDD 3.05 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo ANP ATPlike 11 - 489 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STK3 STK3_HUMAN 4LG4A 2.42 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 18 - 308 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STK3 STK3_HUMAN 4LG4B 2.42 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 18 - 308 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STK3 STK3_HUMAN 4LG4C 2.42 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 18 - 307 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STK3 STK3_HUMAN 4LG4E 2.42 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 18 - 308 0 None D146N Serine/threonine-protein kinase 3 Homo sapiens
STE STK4 STK4_HUMAN 9IICA 2.78 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 11 - 308 0 None K59R Serine/threonine-protein kinase 4 Homo sapiens
STE STK4 STK4_HUMAN 9IICB 2.78 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 11 - 311 0 None K59R Serine/threonine-protein kinase 4 Homo sapiens
TKL BRAF BRAF_HUMAN 3SKCA 3.2 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno BR2 Type1 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4E26B 2.55 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaoii APEdist_nnoo 734 Type1 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HIEA 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HIEB 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HIEC 3.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HIED 3.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_nnoo P06 Type1 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7P3VA 2.37 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 5I4 Type1.5_Back 448 - 719 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7P3VB 2.37 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 5I4 Type1.5_Back 448 - 719 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4CQEB 2.3 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno CQE Type1.5_Back 448 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV2A 2.5 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P06 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV2B 2.5 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno P06 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5CSWB 2.66 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn P06 Type1.5_Back 447 - 721 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6V2UB 3.78 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn P06 Type1.5_Back 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2NRYA 2.15 Inactive DFGin‑BLBminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 458 0 TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 2NRYB 2.15 Inactive DFGin‑BLBminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 164 - 458 0 TPO345 None Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL MAP3K12 M3K12_HUMAN 5CENA 1.7 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaooi APEdist_iioo No_ligand No_ligand 117 - 397 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 2EVAA 2.0 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno ADN Type1 31 - 305 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 4GS6A 2.2 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 1FM Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 4L3PA 2.68 Inactive DFGin‑BLBminus in-in none-none nonTYR APEdihe_aaiii APEdist_nnni 1UH Type1 31 - 497 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5JGBA 2.8 Inactive DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaoii APEdist_nnno 6JV Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0UC 2.91 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo 324 Type1 339 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9O0VC 3.5 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoo 324 Type1 339 - 614 0 None Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6S1FA 3.11 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6S1FC 3.11 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno KRE Type1 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR8B 2.79 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo XYW Type1.5_Back 8 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TYR EGFR EGFR_HUMAN 7JXIC 3.0 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4RJ6A 2.7 Inactive DFGin‑BLBminus in-in in-none TYR APEdihe_nniai APEdist_aaai 3R0 Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5EM6A 2.78 Inactive DFGin‑BLBminus in-in in-none TYR APEdihe_nniai APEdist_aaai 5Q3 Type1.5_Back 697 - 1019 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8A2DA 1.11 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nniai APEdist_aaai KXY Type3 701 - 1021 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5I9WA 1.359 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nniai APEdist_aaai ANP ATPlike 605 - 895 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 7KJCA 2.3 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_niiai APEdist_aaai ACP ATPlike 590 - 976 0 None S901E Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 7KJCB 2.3 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ACP ATPlike 590 - 965 0 None S901E Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 7KJAA 1.75 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan ACP ATPlike 590 - 976 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5I9XA 1.427 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DB8 Type1 604 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5I9YA 1.228 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_nnnai APEdist_aaan 1N1 Type1 600 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5I9ZA 1.698 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_nniai APEdist_aaai 627 Type1 604 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5IA0B 1.948 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_nniai APEdist_aaai A5B Type1 600 - 882 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5IA0C 1.948 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan A5B Type1 600 - 890 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5IA3A 1.788 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_nniai APEdist_aaai P17 Type1 602 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NJZA 1.768 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nniai APEdist_aaai 8ZH Type1 604 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NK1A 1.548 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 90N Type1 604 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NK2A 1.649 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 8ZZ Type1 598 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NK4A 1.45 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 90E Type1 601 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NK5A 1.329 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 90K Type1 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NK6A 1.267 Inactive DFGin‑BLBminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 90W Type1 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NK7A 1.889 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 8ZZ Type1 604 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NK9A 1.588 Inactive DFGin‑BLBminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 912 Type1 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NKBA 1.5 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 8ZT Type1 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NKCA 1.448 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_niiai APEdist_aaai 90T Type1 601 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NKDA 1.408 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 91K Type1 600 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NKEA 1.39 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 90B Type1 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NKFA 1.099 Inactive DFGin‑BLBminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 8ZN Type1 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NKGA 1.1 Inactive DFGin‑BLBminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 8ZK Type1 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NKHA 1.29 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 8ZQ Type1 601 - 895 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5NKIA 1.675 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 8ZW Type1 604 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8BK0A 1.7 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_nniai APEdist_aaai QJI Type1 605 - 887 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 5IA2A 1.619 Inactive DFGin‑BLBminus in-out out-in TYR APEdihe_iiiai APEdist_aaai L66 Type1.5_Back 598 - 888 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA7 EPHA7_HUMAN 7EEFA 2.6 Inactive DFGin‑BLBminus in-in none-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 606 - 899 0 None G656E Ephrin type-A receptor 7 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 6FNKA 1.049 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DXK Type1 604 - 889 0 None Y774E,A803V,V870I Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 6FNMA 1.157 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1 608 - 889 0 None Y774E,A803V,V870I Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 4AW5A 2.33 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nniai APEdist_aaai 30K Type1 607 - 888 0 None None Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 2VWXA 1.65 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7X4 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 2VWYA 1.65 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7X5 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 2VWZA 1.65 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7X6 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 2VX0A 2.1 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7X7 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 2VX1A 1.65 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7X8 Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 2X9FA 1.75 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai X9F Type1 608 - 888 0 None Y774E Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 4BB4A 1.65 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 32W Type1 606 - 888 0 None Y774E Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 2XVDA 1.7 Inactive DFGin‑BLBminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AS6 Type1.5_Back 607 - 888 0 None Y774E Ephrin type-B receptor 4 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 7PCDA 1.77 Inactive DFGin‑BLBminus out-out out-none TYR APEdihe_nniai APEdist_aaai 70I Type1.5_Back 710 - 991 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR ERBB2 ERBB2_HUMAN 7JXHA 3.27 Inactive DFGin‑BLBminus out-out out-out TYR APEdihe_nniai APEdist_aaao VOY Type1.5_Back 706 - 992 0 None None Receptor tyrosine-protein kinase erbB-2 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 3KXXA 3.2 Inactive DFGin‑BLBminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 461 - 765 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR2 FGFR2_HUMAN 6V6QC 2.46 Inactive DFGin‑BLBminus in-in in-out TYR APEdihe_oiiai APEdist_aaai ACP ATPlike 467 - 766 0 PTR656 Y466F,Y561F,Y566F,Y575F,Y586F,Y588F,Y608F,Y616F,Y657F,Y733F Fibroblast growth factor receptor 2 Homo sapiens
TYR IGF1R IGF1R_HUMAN 3QQUA 2.9 Inactive DFGin‑BLBminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 01P Type1 991 - 1285 0 None None Insulin-like growth factor 1 receptor Homo sapiens
TYR LCK LCK_HUMAN 3B2WA 2.3 Inactive DFGin‑BLBminus in-in out-out TYR APEdihe_oiiai APEdist_aaai 9NH Type1 238 - 500 0 None None Tyrosine-protein kinase Lck Homo sapiens
TYR MERTK MERTK_HUMAN 7AVYA 2.31 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S4E Type1 576 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7AW2A 2.1 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S4W Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7OLSA 1.89 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan VJZ Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7OLVA 2.13 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan VK2 Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7OLXA 1.98 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan VK5 Type1.5_Front 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
TYR MET MET_HUMAN 3Q6UA 1.6 Inactive DFGin‑BLBminus in-out none-none TYR APEdihe_nniai APEdist_aaai AME Allosteric 1048 - 1348 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR PDGFRA A0A0B4J203_HUMAN 8XRRA 2.57 Inactive DFGin‑BLBminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1LV8 Type1 338 - 730 0 None None receptor protein-tyrosine kinase Homo sapiens
TYR PTK2 FAK1_HUMAN 2IJMB 2.187 Inactive DFGin‑BLBminus in-out none-out TYR APEdihe_nnoai APEdist_aaao ADP ATPlike 414 - 689 0 None None Focal adhesion kinase 1 Homo sapiens
TYR SRC SRC_HUMAN 1FMKA 1.5 Inactive DFGin‑BLBminus out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 86 - 536 0 PTR530 None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TKL LYR4 G7K7K0_MEDTR 8PS7B 2.1 Pseudo DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_iioo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
CAMK BRSK2 BRSK2_MOUSE 4YNZA 2.0 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 15 - 342 0 None None Serine/threonine-protein kinase BRSK2 Mus musculus
CAMK BRSK2 BRSK2_MOUSE 4YNZB 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 15 - 342 0 None None Serine/threonine-protein kinase BRSK2 Mus musculus
CAMK BRSK2 BRSK2_MOUSE 4YOMB 2.49 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oioo No_ligand No_ligand 13 - 342 0 None None Serine/threonine-protein kinase BRSK2 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8VA 1.479 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SLV Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8WA 1.5 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo JND Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8XA 1.73 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SLY Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R93A 1.489 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SOJ Allosteric 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R94A 1.45 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SOV Allosteric 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R95A 1.59 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SQ4 Allosteric 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R96A 1.767 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SQ7 Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R98A 1.68 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SQG Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9AA 1.53 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SQM Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9BA 1.657 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo JGM Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9GA 1.73 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo RGY Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9HA 1.49 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SQV Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9OA 1.6 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 54F Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9SA 1.7 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo A9B Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9TA 1.8 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 6T5 Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9VA 1.45 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SSY Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9XA 1.72 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo NZ4 Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9ZA 1.66 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo AYS Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA3A 1.57 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SVD Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA4A 1.59 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SVG Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA5A 1.54 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SVJ Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SOIA 1.55 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo LOK Allosteric 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SO1A 1.66 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo LO5 Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SO2A 1.6 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo JGG Allosteric 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SO4A 1.51 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo LO8 Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SODA 1.87 Inactive DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaooi APEdist_oooo LOE Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SOTA 1.54 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo LOQ Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9MA 1.809 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo A7K, A7K Allosteric, Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 1LEWA 2.3 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 5 - 354 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 1LEZA 2.3 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4KA3A 2.707 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 4 - 354 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 8YPFA 2.0 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 8YPEA 1.95 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 1 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P4KA 2.304 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 4 - 353 0 None S28A Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5UOJA 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 8YP8A 2.14 Inactive DFGin‑BLBminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 1 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7Z9TAAA 2.6 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaoio APEdist_iioo 87B Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R90A 1.619 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SNJ Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R91A 1.731 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SNV Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R92A 1.66 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SO7 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R99A 1.89 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SU7 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9CA 1.74 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 7ZC Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9FA 1.986 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SQP Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9IA 1.813 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SQY Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9JA 1.52 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo LXS Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9LA 1.47 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SRJ Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9NA 1.688 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo JFS Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9PA 1.72 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SFY Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9RA 1.76 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo K3D Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9YA 1.57 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SU7 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA0A 1.91 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaooi APEdist_oooo JFS Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA2A 1.57 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SV4 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA6A 1.86 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SVM Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOPB 2.049 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo SB4 Type1 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOPC 2.049 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo SB4 Type1 3 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOQA 2.319 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo SB4 Type1 3 - 354 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOQB 2.319 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo SB4 Type1 3 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOQC 2.319 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo SB4 Type1 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOQD 2.319 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo SB4 Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8UA 1.48 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo SLS Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA7A 1.92 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SW7 Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA8A 1.78 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 2O6 Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8YA 1.679 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SMV Type3 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8ZA 1.65 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SN4 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R97A 1.438 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo RUY Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9DA 1.69 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo N9J Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9EA 1.775 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo S7S Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9KA 1.498 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SR4 Type3 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9QA 1.645 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo LVD Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9WA 1.89 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo STV Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA1A 1.61 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo PO6 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA9A 1.68 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SWD Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7Z9TBBB 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 87B, ATP Type3, Allosteric 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
OTHER PKNA PKNA_MYCTU 4OW8A 2.03 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 3 - 283 0 None None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4X3FA 2.9 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 3 - 289 0 SEP46,TPO152,TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4X3FB 2.9 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 1 - 289 0 TPO21,TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4X3FC 2.9 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 2 - 289 0 TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3F61A 1.8 Inactive DFGin‑BLBminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn ADP ATPlike 1 - 290 0 None L33D,V222D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIA 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIB 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIC 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORID 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORKA 1.6 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 1 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORLA 2.9 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 3 - 289 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORPA 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo AGS ATPlike 1 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORTA 1.9 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 1 - 289 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORMA 2.5 Inactive DFGin‑BLBminus in-out out-none nonTYR APEdihe_aanii APEdist_nnnn AGS ATPlike 10 - 289 0 None D76A Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3OROA 1.9 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaooo APEdist_oioo AGS, NHE ATPlike, Allosteric 9 - 288 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M06B 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn ADP ATPlike 2 - 255 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M07A 2.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M07B 2.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M06A 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 255 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5XKAA 1.599 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 2 - 260 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5XKAB 1.599 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 2 - 257 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M09A 2.98 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A,R136N Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M09B 2.98 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 2 - 256 0 None C20A,R136N Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M08A 3.03 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A,R136A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M08B 3.03 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A,R136A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER MLKL D3ZKP6_RAT 6VBZA 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 183 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
OTHER MLKL D3ZKP6_RAT 6VBZB 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 182 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
OTHER WNK1 WNK1_RAT 6CN9B 1.8 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 210 - 481 0 None None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 7UOSA 2.9 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo WIB Type1 211 - 481 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 6OL2A 2.1 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo MU7 Type1.5_Back 203 - 481 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
CAMK RAD53 RAD53_YEAST 5XZVB 3.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_iooo ANP ATPlike 32 - 466 0 None None Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
CAMK RAD53 RAD53_YEAST 5XZWB 2.8 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 32 - 466 0 None None Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY5A 2.0 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 594 - 996 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY5B 2.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno ANP ATPlike 594 - 983 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYDA 2.75 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo ATP ATPlike 594 - 996 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYDB 2.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnoo ATP ATPlike 594 - 983 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY4A 1.95 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 594 - 996 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY4B 1.95 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 594 - 983 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCA 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 594 - 989 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCB 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 594 - 984 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCC 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 594 - 995 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCD 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 594 - 984 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEA 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 594 - 995 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEB 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno No_ligand No_ligand 594 - 984 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEC 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 594 - 996 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXED 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 594 - 984 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEE 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 594 - 995 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEF 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 594 - 984 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
CAMK CDPK1 Q9BJF5_TOXGO 4YGAE 2.94 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 45 - 505 0 None None non-specific serine/threonine protein kinase Toxoplasma gondii
OTHER PKNB A0A0U5FKB2_XANCI 9EEDA 2.1 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooi 12C Type1 82 - 363 0 None M164A Kinase domain protein Xanthomonas citri pv. citri

All / BLBminus / All

Total number of chains: 155
Active chains: 0
Total number of genes: 20
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 155 100.0% 5R97A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK CIPK23 CIPKN_ARATH 4CZTA 2.3 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo CPS Type1 25 - 315 0 None None CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZTB 2.3 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo CPS Type1 25 - 313 0 None None CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZUA 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo CPS Type1 25 - 320 0 None T190D CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZTC 2.3 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo CPS, CPS Type1, Allosteric 28 - 313 0 None None CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZUB 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo CPS, CPS Type1, Allosteric 25 - 313 0 None T190D CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZUC 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo CPS, CPS Type1, Allosteric 27 - 312 0 None T190D CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZUD 1.9 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo CPS, CPS Type1, Allosteric 25 - 324 0 None T190D CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK23 CIPKN_ARATH 4CZTD 2.3 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioo CPS, CPS, CPS Type1, Allosteric, Allosteric 25 - 324 0 None None CBL-interacting serine/threonine-protein kinase 23 Arabidopsis thaliana
CAMK CIPK24 CIPKO_ARATH 4D28C 3.3 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 7 - 289 0 None P81K,E107K,S109D,C127S,T168D,S228D,L266K CBL-interacting serine/threonine-protein kinase 24 Arabidopsis thaliana
CMGC MPK6 MPK6_ARATH 5CI6A 3.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaiii APEdist_nnno No_ligand No_ligand 32 - 393 0 None None Mitogen-activated protein kinase 6 Arabidopsis thaliana
OTHER BIR2 BIR2_ARATH 4L68A 2.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiai APEdist_nioi PDO Allosteric 272 - 600 0 None None Inactive LRR receptor-like serine/threonine-protein kinase BIR2 Arabidopsis thaliana
OTHER BIR2 BIR2_ARATH 4L68B 2.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 271 - 600 0 None None Inactive LRR receptor-like serine/threonine-protein kinase BIR2 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTVA 2.886 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 639 0 None D489A Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
TKL SOBIR1 SBIR1_ARATH 7CTVB 2.886 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_oooo ANP ATPlike 326 - 640 0 None D489A Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 Arabidopsis thaliana
OTHER STKLD1 F1MSZ0_BOVIN 9FQRXR 5.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoai APEdist_oooo No_ligand No_ligand 1 - 610 0 None None Serine/threonine kinase like domain containing 1 Bos taurus
TKL ROCO4 ROCO4_DICDI 4F0GA 2.0 Inactive DFGin‑BLBminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1019 - 1292 0 None None Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
OTHER MLKL F6S337_HORSE 6VC0A 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 536 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER MLKL F6S337_HORSE 6VC0B 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 258 - 537 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER MLKL F6S337_HORSE 6VC0C 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 541 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
TYR SRC SRC_CHICK 3U51A 2.241 Inactive DFGin‑BLBminus out-out none-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 261 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3U51B 2.241 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan No_ligand No_ligand 261 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3SVVA 2.204 Inactive DFGin‑BLBminus in-in out-none TYR APEdihe_nnnai APEdist_aaan VSP Type1.5_Back 257 - 533 0 None T338C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3SVVB 2.204 Inactive DFGin‑BLBminus in-in none-none TYR APEdihe_nnnai APEdist_aaan VSP Type1.5_Back 256 - 533 0 None T338C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4DGGA 2.65 Inactive DFGin‑BLBminus out-none none-out TYR APEdihe_nniai APEdist_aaao I76 Type1.5_Front 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5J5SA 2.153 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan 6G3 Type1.5_Front 258 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5J5SB 2.153 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nnnai APEdist_aaan 6G3 Type1.5_Front 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
CMGC CDK A8BZ95_GIAIC 3GC0A 2.0 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaoni APEdist_nooo AMP ATPlike 11 - 308 0 None None cyclin-dependent kinase Giardia intestinalis
CMGC CDK A8BZ95_GIAIC 3GBZA 1.85 Inactive DFGin‑BLBminus out-none out-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 11 - 308 0 None None cyclin-dependent kinase Giardia intestinalis
TKL LYR4 G7K7K0_MEDTR 8PS7B 2.1 Pseudo DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_iioo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
CAMK BRSK2 BRSK2_MOUSE 4YNZA 2.0 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 15 - 342 0 None None Serine/threonine-protein kinase BRSK2 Mus musculus
CAMK BRSK2 BRSK2_MOUSE 4YNZB 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn No_ligand No_ligand 15 - 342 0 None None Serine/threonine-protein kinase BRSK2 Mus musculus
CAMK BRSK2 BRSK2_MOUSE 4YOMB 2.49 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaioi APEdist_oioo No_ligand No_ligand 13 - 342 0 None None Serine/threonine-protein kinase BRSK2 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8VA 1.479 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SLV Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8WA 1.5 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo JND Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8XA 1.73 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SLY Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R93A 1.489 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SOJ Allosteric 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R94A 1.45 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SOV Allosteric 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R95A 1.59 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SQ4 Allosteric 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R96A 1.767 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SQ7 Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R98A 1.68 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SQG Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9AA 1.53 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SQM Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9BA 1.657 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo JGM Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9GA 1.73 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo RGY Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9HA 1.49 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SQV Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9OA 1.6 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 54F Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9SA 1.7 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo A9B Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9TA 1.8 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 6T5 Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9VA 1.45 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SSY Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9XA 1.72 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo NZ4 Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9ZA 1.66 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo AYS Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA3A 1.57 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SVD Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA4A 1.59 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SVG Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA5A 1.54 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SVJ Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SOIA 1.55 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo LOK Allosteric 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SO1A 1.66 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo LO5 Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SO2A 1.6 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo JGG Allosteric 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SO4A 1.51 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo LO8 Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SODA 1.87 Inactive DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaooi APEdist_oooo LOE Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6SOTA 1.54 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo LOQ Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9MA 1.809 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo A7K, A7K Allosteric, Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 1LEWA 2.3 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 5 - 354 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 1LEZA 2.3 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4KA3A 2.707 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 4 - 354 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 8YPFA 2.0 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 8YPEA 1.95 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 1 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P4KA 2.304 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 4 - 353 0 None S28A Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5UOJA 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 8YP8A 2.14 Inactive DFGin‑BLBminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 1 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7Z9TAAA 2.6 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaoio APEdist_iioo 87B Type1 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R90A 1.619 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SNJ Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R91A 1.731 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SNV Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R92A 1.66 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SO7 Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R99A 1.89 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SU7 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9CA 1.74 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 7ZC Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9FA 1.986 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SQP Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9IA 1.813 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SQY Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9JA 1.52 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo LXS Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9LA 1.47 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SRJ Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9NA 1.688 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo JFS Type1 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9PA 1.72 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SFY Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9RA 1.76 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo K3D Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9YA 1.57 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo SU7 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA0A 1.91 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaooi APEdist_oooo JFS Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA2A 1.57 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SV4 Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA6A 1.86 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SVM Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOPB 2.049 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo SB4 Type1 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOPC 2.049 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo SB4 Type1 3 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOQA 2.319 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo SB4 Type1 3 - 354 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOQB 2.319 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo SB4 Type1 3 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOQC 2.319 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo SB4 Type1 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 4LOQD 2.319 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo SB4 Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8UA 1.48 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo SLS Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA7A 1.92 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SW7 Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA8A 1.78 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 2O6 Type1.5_Back 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8YA 1.679 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SMV Type3 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8ZA 1.65 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SN4 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R97A 1.438 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo RUY Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9DA 1.69 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo N9J Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9EA 1.775 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo S7S Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9KA 1.498 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SR4 Type3 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9QA 1.645 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo LVD Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9WA 1.89 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo STV Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA1A 1.61 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo PO6 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA9A 1.68 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SWD Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7Z9TBBB 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo 87B, ATP Type3, Allosteric 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
OTHER PKNA PKNA_MYCTU 4OW8A 2.03 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 3 - 283 0 None None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4X3FA 2.9 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 3 - 289 0 SEP46,TPO152,TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4X3FB 2.9 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 1 - 289 0 TPO21,TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNA PKNA_MYCTU 4X3FC 2.9 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 2 - 289 0 TPO224 None Serine/threonine-protein kinase PknA Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3F61A 1.8 Inactive DFGin‑BLBminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn ADP ATPlike 1 - 290 0 None L33D,V222D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIA 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIB 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORIC 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORID 2.0 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno AGS ATPlike 10 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORKA 1.6 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 1 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORLA 2.9 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn AGS ATPlike 3 - 289 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORPA 2.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo AGS ATPlike 1 - 290 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORTA 1.9 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 1 - 289 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3ORMA 2.5 Inactive DFGin‑BLBminus in-out out-none nonTYR APEdihe_aanii APEdist_nnnn AGS ATPlike 10 - 289 0 None D76A Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNB PKNB_MYCTU 3OROA 1.9 Inactive DFGin‑BLBminus in-out out-out nonTYR APEdihe_aaooo APEdist_oioo AGS, NHE ATPlike, Allosteric 9 - 288 0 None L33D Serine/threonine-protein kinase PknB Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M06B 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn ADP ATPlike 2 - 255 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M07A 2.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M07B 2.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M06A 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 255 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5XKAA 1.599 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 2 - 260 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5XKAB 1.599 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 2 - 257 0 None None Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M09A 2.98 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A,R136N Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M09B 2.98 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 2 - 256 0 None C20A,R136N Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M08A 3.03 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A,R136A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER PKNI PKNI_MYCTU 5M08B 3.03 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 1 - 256 0 None C20A,R136A Serine/threonine-protein kinase PknI Mycobacterium tuberculosis
OTHER MLKL D3ZKP6_RAT 6VBZA 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 183 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
OTHER MLKL D3ZKP6_RAT 6VBZB 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 182 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
OTHER WNK1 WNK1_RAT 6CN9B 1.8 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 210 - 481 0 None None Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 7UOSA 2.9 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo WIB Type1 211 - 481 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
OTHER WNK1 WNK1_RAT 6OL2A 2.1 Inactive DFGin‑BLBminus out-na out-out nonTYR APEdihe_aaiio APEdist_oooo MU7 Type1.5_Back 203 - 481 0 None S382A Serine/threonine-protein kinase WNK1 Rattus norvegicus
CAMK RAD53 RAD53_YEAST 5XZVB 3.1 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_iooo ANP ATPlike 32 - 466 0 None None Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
CAMK RAD53 RAD53_YEAST 5XZWB 2.8 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 32 - 466 0 None None Serine/threonine-protein kinase RAD53 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY5A 2.0 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn ANP ATPlike 594 - 996 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY5B 2.0 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno ANP ATPlike 594 - 983 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYDA 2.75 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo ATP ATPlike 594 - 996 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYDB 2.75 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnoo ATP ATPlike 594 - 983 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY4A 1.95 Inactive DFGin‑BLBminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 594 - 996 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZY4B 1.95 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 594 - 983 0 None R794G eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCA 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 594 - 989 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCB 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 594 - 984 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCC 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 594 - 995 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZYCD 3.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 594 - 984 0 None None eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEA 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 594 - 995 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEB 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno No_ligand No_ligand 594 - 984 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEC 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 594 - 996 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXED 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 594 - 984 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEE 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno No_ligand No_ligand 594 - 995 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
OTHER GCN2-2 GCN2_YEAST 1ZXEF 2.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 594 - 984 0 None D835N eIF-2-alpha kinase GCN2 Saccharomyces cerevisiae
CAMK CDPK1 Q9BJF5_TOXGO 4YGAE 2.94 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 45 - 505 0 None None non-specific serine/threonine protein kinase Toxoplasma gondii
OTHER PKNB A0A0U5FKB2_XANCI 9EEDA 2.1 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooi 12C Type1 82 - 363 0 None M164A Kinase domain protein Xanthomonas citri pv. citri