Ligand: EZV

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 3F5XC
DFGin BLBminus 1 33.3% 3EZVA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK2 CDK2_HUMAN 3F5XA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioi EZV Type1.5_Back 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3F5XC 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii EZV Type1.5_Back 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3EZVA 1.99 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo EZV Type1 1 - 298 0 None None Cyclin-dependent kinase 2

Ligand: EZV

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 3F5XC
DFGin BLBminus 1 33.3% 3EZVA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK2 CDK2_HUMAN 3F5XA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioi EZV Type1.5_Back 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3F5XC 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii EZV Type1.5_Back 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 3EZVA 1.99 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnoo EZV Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens

Ligand: EZV

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism