Ligand: 7TW

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 3 100.0% 7RWFA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK2 CDK2_HUMAN 8FOWA 1.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nooo 1QK, 7TW Type1, Type3 3 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8FP0A 1.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo RRC, 7TW Type1, Type3 2 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7RWFA 1.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 7TW Type3 1 - 298 0 None None Cyclin-dependent kinase 2

Ligand: 7TW

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 3 100.0% 7RWFA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK2 CDK2_HUMAN 8FOWA 1.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nooo 1QK, 7TW Type1, Type3 3 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 8FP0A 1.6 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo RRC, 7TW Type1, Type3 2 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7RWFA 1.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 7TW Type3 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens

Ligand: 7TW

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism