Ligand: PVB

Total number of chains: 4
Active chains: 1
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 2 50.0% 6BL8A
DFGin BLAminus 1 25.0% 2X7GA
DFGin BLBtrans 1 25.0% 1CKPA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK2 CDK2_HUMAN 1CKPA 2.05 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_nnno PVB Type1 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC SRPK2 SRPK2_HUMAN 2X7GA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii PVB Type1 70 - 688 0 None None SRSF protein kinase 2
TYR ABL1 ABL1_HUMAN 6BL8A 2.5 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai PVB Type1 233 - 502 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6BL8B 2.5 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai PVB Type1 233 - 504 0 None None Tyrosine-protein kinase ABL1

Ligand: PVB

Total number of chains: 6
Active chains: 1
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 2 33.3% 6BL8A
None None 2 33.3% 1V0PA
DFGin BLAminus 1 16.7% 2X7GA
DFGin BLBtrans 1 16.7% 1CKPA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK2 CDK2_HUMAN 1CKPA 2.05 Inactive DFGin‑BLBtrans out-out out-out nonTYR APEdihe_aaiii APEdist_nnno PVB Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC SRPK2 SRPK2_HUMAN 2X7GA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii PVB Type1 70 - 688 0 None None SRSF protein kinase 2 Homo sapiens
TYR ABL1 ABL1_HUMAN 6BL8A 2.5 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai PVB Type1 233 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 6BL8B 2.5 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai PVB Type1 233 - 504 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
CMGC CRK2 CDK2H_PLAFK 1V0PA 2.0 Inactive None‑None out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo PVB Type1 1 - 286 0 None V161I Cyclin-dependent kinase 2 homolog Plasmodium falciparum
CMGC CRK2 CDK2H_PLAFK 1V0PB 2.0 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn PVB Type1 2 - 286 0 None V161I Cyclin-dependent kinase 2 homolog Plasmodium falciparum

Ligand: PVB

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
None None 2 100.0% 1V0PA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CRK2 CDK2H_PLAFK 1V0PA 2.0 Inactive None‑None out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo PVB Type1 1 - 286 0 None V161I Cyclin-dependent kinase 2 homolog Plasmodium falciparum
CMGC CRK2 CDK2H_PLAFK 1V0PB 2.0 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn PVB Type1 2 - 286 0 None V161I Cyclin-dependent kinase 2 homolog Plasmodium falciparum