Ligand: GEW

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 6HMPA
DFGinter None 1 33.3% 6HWVA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CK1 CSNK1D KC1D_HUMAN 6HMPA 2.039 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GEW Type1 8 - 294 0 None None Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 6HMPB 2.039 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GEW Type1 1 - 293 0 None None Casein kinase I isoform delta
CMGC MAPK14 MK14_HUMAN 6HWVA 1.7 Inactive DFGinter‑None in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn GEW Type1 5 - 352 0 None None Mitogen-activated protein kinase 14

Ligand: GEW

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 6HMPA
DFGinter None 1 33.3% 6HWVA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CK1 CSNK1D KC1D_HUMAN 6HMPA 2.039 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GEW Type1 8 - 294 0 None None Casein kinase I isoform delta Homo sapiens
CK1 CSNK1D KC1D_HUMAN 6HMPB 2.039 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GEW Type1 1 - 293 0 None None Casein kinase I isoform delta Homo sapiens
CMGC MAPK14 MK14_HUMAN 6HWVA 1.7 Inactive DFGinter‑None in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn GEW Type1 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens

Ligand: GEW

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism