| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 3 | AF-O00506-K1A |
| DFGinter | None | 1 | 4NZWB |
| PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AF-O00506-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 12 - 278 | None | None | 0 |
| 2XIKA | 1.97 | Inactive | DFGin | BLAminus | in-out | in-in | J60 | Type1 | 3 - 292 | None | X174 | 0 |
| 7Z4VA | 1.644 | Active | DFGin | BLAminus | in-in | in-in | IB5 | Type1 | 3 - 293 | None | X174 | 0 |
| 4NZWB | 3.583 | Inactive | DFGinter | None | out-out | none-in | J60 | Type1 | 11 - 292 | D158A | None | 14 |
| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 3 | AF-O00506-K1A |
| DFGinter | None | 1 | 4NZWB |
| Organism | UniprotID | PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Homo sapiens | STK25_HUMAN | AF-O00506-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 12 - 278 | None | None | 0 |
| Homo sapiens | STK25_HUMAN | 2XIKA | 1.97 | Inactive | DFGin | BLAminus | in-out | in-in | J60 | Type1 | 3 - 292 | None | X174 | 0 |
| Homo sapiens | STK25_HUMAN | 7Z4VA | 1.644 | Active | DFGin | BLAminus | in-in | in-in | IB5 | Type1 | 3 - 293 | None | X174 | 0 |
| Homo sapiens | STK25_HUMAN | 4NZWB | 3.583 | Inactive | DFGinter | None | out-out | none-in | J60 | Type1 | 11 - 292 | D158A | None | 14 |