STE_STK25 (Serine/threonine-protein kinase 25)

Total number of chains: 5
Active chains: 3
Uniprot: STK25_HUMAN
Kinase Domain Residues: 20 - 270
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 80.0% AF-O00506-K1A
DFGinter None 1 20.0% 4NZWB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-O00506-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 278 0 None None Serine/threonine-protein kinase 25
AF-O00506-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 278 0 None None Serine/threonine-protein kinase 25
7Z4VA 1.644 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IB5 Type1 3 - 293 0 TPO174 None Serine/threonine-protein kinase 25
2XIKA 1.97 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii J60 Type1 3 - 292 0 TPO174 None Serine/threonine-protein kinase 25
4NZWB 3.583 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnni J60 Type1 11 - 292 0 None D158A Serine/threonine-protein kinase 25

STE_STK25 (Serine/threonine-protein kinase 25)

Total number of chains: 5
Active chains: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 80.0% AF-O00506-K1A
DFGinter None 1 20.0% 4NZWB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STK25_HUMAN AF-O00506-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 278 0 None None Serine/threonine-protein kinase 25 Homo sapiens
STK25_HUMAN AF-O00506-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 12 - 278 0 None None Serine/threonine-protein kinase 25 Homo sapiens
STK25_HUMAN 7Z4VA 1.644 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IB5 Type1 3 - 293 0 TPO174 None Serine/threonine-protein kinase 25 Homo sapiens
STK25_HUMAN 2XIKA 1.97 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii J60 Type1 3 - 292 0 TPO174 None Serine/threonine-protein kinase 25 Homo sapiens
STK25_HUMAN 4NZWB 3.583 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnni J60 Type1 11 - 292 0 None D158A Serine/threonine-protein kinase 25 Homo sapiens

STE_STK25 (Serine/threonine-protein kinase 25)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism