CAMK_AURKB (Aurora kinase B)

Total number of chains: 3
Active chains: 2
Uniprot: AURKB_HUMAN
Kinase Domain Residues: 77 - 327
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% AF-Q96GD4-K1A
DFGinter None 1 33.3% 4AF3A

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q96GD4-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 69 - 335 0 None None Aurora kinase B
AF-Q96GD4-K3A -1.0 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 69 - 335 0 None None Aurora kinase B
4AF3A 2.75 Inactive DFGinter‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn VX6 Type1 70 - 338 0 None None Aurora kinase B

CAMK_AURKB (Aurora kinase B)

Total number of chains: 3
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% AF-Q96GD4-K1A
DFGinter None 1 33.3% 4AF3A

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AURKB_HUMAN AF-Q96GD4-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 69 - 335 0 None None Aurora kinase B Homo sapiens
AURKB_HUMAN AF-Q96GD4-K3A -1.0 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 69 - 335 0 None None Aurora kinase B Homo sapiens
AURKB_HUMAN 4AF3A 2.75 Inactive DFGinter‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn VX6 Type1 70 - 338 0 None None Aurora kinase B Homo sapiens

CAMK_AURKB (Aurora kinase B)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism