TTBK2 (Tau-tubulin kinase 2)

Group: CK1
Uniprot: TTBK2_HUMAN
Domain boundary: 21 - 282


Total number of chains: 11
Spatial Dihedral Chains Representative
DFGin BLAminus 5 AF-Q6IQ55-K1A
DFGin ABAminus 6 7Q8ZA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
7Q8YA 1.6 Inactive DFGin ABAminus in-in in-in 9IV Type1 6 - 299 None None 0
7Q8YB 1.6 Inactive DFGin ABAminus in-in in-in 9IV Type1 7 - 299 None None 0
7Q8ZA 1.57 Inactive DFGin ABAminus in-in in-in 9IK Type1 6 - 299 None None 0
7Q8ZB 1.57 Inactive DFGin ABAminus in-in in-in 9IK Type1 7 - 299 None None 0
7Q90A 1.6 Inactive DFGin ABAminus in-in in-in 9IS Type1 6 - 299 None None 0
7Q90B 1.6 Inactive DFGin ABAminus in-in in-in 9IS Type1 7 - 299 None None 0
AF-Q6IQ55-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 13 - 290 None None 0
6VRFA 1.5 Active DFGin BLAminus in-in in-in ADP Type1 9 - 298 None None 0
6VRFB 1.5 Active DFGin BLAminus in-in in-in ADP Type1 9 - 298 None None 0
6U0KA 1.744 Active DFGin BLAminus in-in in-in DTQ Type1 8 - 298 None None 0
6U0KB 1.744 Active DFGin BLAminus in-in in-in DTQ Type1 8 - 299 None None 0

TTBK2 (Tau-tubulin kinase 2)

Group: CK1
Total number of chains: 11
Spatial Dihedral Chains Representative
DFGin BLAminus 5 AF-Q6IQ55-K1A
DFGin ABAminus 6 7Q8ZA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens TTBK2_HUMAN 7Q8YA 1.6 Inactive DFGin ABAminus in-in in-in 9IV Type1 6 - 299 None None 0
Homo sapiens TTBK2_HUMAN 7Q8YB 1.6 Inactive DFGin ABAminus in-in in-in 9IV Type1 7 - 299 None None 0
Homo sapiens TTBK2_HUMAN 7Q8ZA 1.57 Inactive DFGin ABAminus in-in in-in 9IK Type1 6 - 299 None None 0
Homo sapiens TTBK2_HUMAN 7Q8ZB 1.57 Inactive DFGin ABAminus in-in in-in 9IK Type1 7 - 299 None None 0
Homo sapiens TTBK2_HUMAN 7Q90A 1.6 Inactive DFGin ABAminus in-in in-in 9IS Type1 6 - 299 None None 0
Homo sapiens TTBK2_HUMAN 7Q90B 1.6 Inactive DFGin ABAminus in-in in-in 9IS Type1 7 - 299 None None 0
Homo sapiens TTBK2_HUMAN AF-Q6IQ55-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 13 - 290 None None 0
Homo sapiens TTBK2_HUMAN 6VRFA 1.5 Active DFGin BLAminus in-in in-in ADP Type1 9 - 298 None None 0
Homo sapiens TTBK2_HUMAN 6VRFB 1.5 Active DFGin BLAminus in-in in-in ADP Type1 9 - 298 None None 0
Homo sapiens TTBK2_HUMAN 6U0KA 1.744 Active DFGin BLAminus in-in in-in DTQ Type1 8 - 298 None None 0
Homo sapiens TTBK2_HUMAN 6U0KB 1.744 Active DFGin BLAminus in-in in-in DTQ Type1 8 - 299 None None 0

TTBK2 (Tau-tubulin kinase 2)

No non-human structures known.