GRK1 (Rhodopsin kinase GRK1)

Group: AGC
Uniprot: GRK1_HUMAN
Domain boundary: 190 - 455


Total number of chains: 1
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q15835-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q15835-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 182 - 463 None None 0

GRK1 (Rhodopsin kinase GRK1)

Group: AGC
Total number of chains: 28
Spatial Dihedral Chains Representative
DFGin BLAminus 27 AF-Q15835-K1A
DFGinter None 1 3C4YB
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Bos taurus GRK1_BOVIN 3C4YA 7.509 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 30 - 532 None None 0
Bos taurus GRK1_BOVIN 4L9IA 2.32 Inactive DFGin BLAminus in-out in-in 8PR Type1 30 - 533 None None 0
Bos taurus GRK1_BOVIN 4L9IB 2.32 Active DFGin BLAminus in-in in-in 8PR Type1 31 - 533 None None 0
Bos taurus GRK1_BOVIN 4WBOA 2.81 Inactive DFGin BLAminus in-out in-in ANW Type1 28 - 533 None None 0
Bos taurus GRK1_BOVIN 4WBOB 2.81 Inactive DFGin BLAminus in-out in-in ANW Type1 30 - 533 None None 0
Bos taurus GRK1_BOVIN 4WBOC 2.81 Inactive DFGin BLAminus in-out in-in ANW Type1 31 - 531 None None 0
Bos taurus GRK1_BOVIN 4WBOD 2.81 Inactive DFGin BLAminus in-out in-in ANW Type1 30 - 531 None None 0
Bos taurus GRK1_BOVIN 3T8OA 2.5 Active DFGin BLAminus in-in in-in ATP Type1 30 - 532 L166K None 0
Bos taurus GRK1_BOVIN 3C4WA 2.7 Active DFGin BLAminus in-in in-in ATP Type1 31 - 533 None X8 0
Bos taurus GRK1_BOVIN 3C4WB 2.7 Active DFGin BLAminus in-in in-in ATP Type1 5 - 533 None X8 0
Bos taurus GRK1_BOVIN 3C4XA 2.9 Active DFGin BLAminus in-in in-in ATP Type1 30 - 533 None None 0
Bos taurus GRK1_BOVIN 3C4XB 2.9 Active DFGin BLAminus in-in in-in ATP Type1 31 - 533 None None 0
Bos taurus GRK1_BOVIN 3C4ZA 1.84 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 None None 0
Bos taurus GRK1_BOVIN 3C50A 2.6 Active DFGin BLAminus in-in in-in ADP Type1 30 - 533 None None 0
Bos taurus GRK1_BOVIN 3C50B 2.6 Active DFGin BLAminus in-in in-in ADP Type1 30 - 533 None None 0
Bos taurus GRK1_BOVIN 3C51A 3.55 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 None None 0
Bos taurus GRK1_BOVIN 3C51B 3.55 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 None None 0
Bos taurus GRK1_BOVIN 3QC9A 2.7 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 T8C,N480C None 0
Bos taurus GRK1_BOVIN 3QC9B 2.7 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 T8C,N480C None 0
Bos taurus GRK1_BOVIN 3QC9C 2.7 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 T8C,N480C None 0
Bos taurus GRK1_BOVIN 3QC9D 2.7 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 T8C,N480C None 0
Bos taurus GRK1_BOVIN 4PNIA 1.85 Active DFGin BLAminus in-in in-in KQQ Type1 30 - 533 None None 0
Bos taurus GRK1_BOVIN 7MT9G 7.0 Inactive DFGin BLAminus in-out in-out SGV SGV SGV SGV SGV SGV Type1 Type1 Type1 Type1 Type1 Type1 6 - 508 None None 0
Bos taurus GRK1_BOVIN 7MT8G 5.8 Active DFGin BLAminus in-in in-in SGV SGV SGV SGV SGV SGV Type1 Type1 Type1 Type1 Type1 Type1 6 - 508 S5E,S488E,T489E None 0
Bos taurus GRK1_BOVIN 7MTAG 4.1 Inactive DFGin BLAminus in-out in-in SGV SGV SGV SGV SGV SGV Type1 Type1 Type1 Type1 Type1 Type1 6 - 508 S5E,S488E,T489E None 0
Bos taurus GRK1_BOVIN 7MTBG 4.0 Active DFGin BLAminus in-in in-in SGV SGV SGV SGV SGV SGV Type1 Type1 Type1 Type1 Type1 Type1 6 - 508 S5E,S488E,T489E None 0
Bos taurus GRK1_BOVIN 3C4YB 7.509 Inactive DFGinter None in-out in-in No_ligand No_ligand 30 - 532 None None 0
Homo sapiens GRK1_HUMAN AF-Q15835-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 182 - 463 None None 0

GRK1 (Rhodopsin kinase GRK1)

Group: AGC
Total number of chains: 27
Spatial Dihedral Chains Representative
DFGin BLAminus 26 3C4ZA
DFGinter None 1 3C4YB
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Bos taurus GRK1_BOVIN 3C4YA 7.509 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 30 - 532 None None 0
Bos taurus GRK1_BOVIN 4L9IA 2.32 Inactive DFGin BLAminus in-out in-in 8PR Type1 30 - 533 None None 0
Bos taurus GRK1_BOVIN 4L9IB 2.32 Active DFGin BLAminus in-in in-in 8PR Type1 31 - 533 None None 0
Bos taurus GRK1_BOVIN 4WBOA 2.81 Inactive DFGin BLAminus in-out in-in ANW Type1 28 - 533 None None 0
Bos taurus GRK1_BOVIN 4WBOB 2.81 Inactive DFGin BLAminus in-out in-in ANW Type1 30 - 533 None None 0
Bos taurus GRK1_BOVIN 4WBOC 2.81 Inactive DFGin BLAminus in-out in-in ANW Type1 31 - 531 None None 0
Bos taurus GRK1_BOVIN 4WBOD 2.81 Inactive DFGin BLAminus in-out in-in ANW Type1 30 - 531 None None 0
Bos taurus GRK1_BOVIN 3T8OA 2.5 Active DFGin BLAminus in-in in-in ATP Type1 30 - 532 L166K None 0
Bos taurus GRK1_BOVIN 3C4WA 2.7 Active DFGin BLAminus in-in in-in ATP Type1 31 - 533 None X8 0
Bos taurus GRK1_BOVIN 3C4WB 2.7 Active DFGin BLAminus in-in in-in ATP Type1 5 - 533 None X8 0
Bos taurus GRK1_BOVIN 3C4XA 2.9 Active DFGin BLAminus in-in in-in ATP Type1 30 - 533 None None 0
Bos taurus GRK1_BOVIN 3C4XB 2.9 Active DFGin BLAminus in-in in-in ATP Type1 31 - 533 None None 0
Bos taurus GRK1_BOVIN 3C4ZA 1.84 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 None None 0
Bos taurus GRK1_BOVIN 3C50A 2.6 Active DFGin BLAminus in-in in-in ADP Type1 30 - 533 None None 0
Bos taurus GRK1_BOVIN 3C50B 2.6 Active DFGin BLAminus in-in in-in ADP Type1 30 - 533 None None 0
Bos taurus GRK1_BOVIN 3C51A 3.55 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 None None 0
Bos taurus GRK1_BOVIN 3C51B 3.55 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 None None 0
Bos taurus GRK1_BOVIN 3QC9A 2.7 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 T8C,N480C None 0
Bos taurus GRK1_BOVIN 3QC9B 2.7 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 T8C,N480C None 0
Bos taurus GRK1_BOVIN 3QC9C 2.7 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 T8C,N480C None 0
Bos taurus GRK1_BOVIN 3QC9D 2.7 Active DFGin BLAminus in-in in-in ADP Type1 31 - 533 T8C,N480C None 0
Bos taurus GRK1_BOVIN 4PNIA 1.85 Active DFGin BLAminus in-in in-in KQQ Type1 30 - 533 None None 0
Bos taurus GRK1_BOVIN 7MT9G 7.0 Inactive DFGin BLAminus in-out in-out SGV SGV SGV SGV SGV SGV Type1 Type1 Type1 Type1 Type1 Type1 6 - 508 None None 0
Bos taurus GRK1_BOVIN 7MT8G 5.8 Active DFGin BLAminus in-in in-in SGV SGV SGV SGV SGV SGV Type1 Type1 Type1 Type1 Type1 Type1 6 - 508 S5E,S488E,T489E None 0
Bos taurus GRK1_BOVIN 7MTAG 4.1 Inactive DFGin BLAminus in-out in-in SGV SGV SGV SGV SGV SGV Type1 Type1 Type1 Type1 Type1 Type1 6 - 508 S5E,S488E,T489E None 0
Bos taurus GRK1_BOVIN 7MTBG 4.0 Active DFGin BLAminus in-in in-in SGV SGV SGV SGV SGV SGV Type1 Type1 Type1 Type1 Type1 Type1 6 - 508 S5E,S488E,T489E None 0
Bos taurus GRK1_BOVIN 3C4YB 7.509 Inactive DFGinter None in-out in-in No_ligand No_ligand 30 - 532 None None 0