6C7Y

JAK1 (Tyrosine-protein kinase JAK1)
Group: TYR
Uniprot: JAK1_HUMAN
Organism: Homo sapiens
Domain boundary: 875 - 1153
Resolu: 2.499

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in ADP Type1 869 - 1153 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       877        887        897        907 
AHFEKRFLKR IRDLGEGHFG KVELCRYdpe GDNTGEQVAV 
       917        927        937        947 
KSLKPesggn HIADLKKEIE ILRNLYHENI VKYKGICTEd 
       957        967        977        987 
ggnGIKLIME FLPSGSLKEY LPKNKNKINL KQQLKYAVQI 
       997       1007       1017       1027 
CKGMDYLGSR QYVHRDLAAR NVLVESEHQV KIGDFGLTKA 
      1037       1047       1057       1067 
IETDKEYYTV KDDRDSPVFW YAPECLMQSK FYIASDVWSF 
      1077       1087       1097       1107 
GVTLHELLTY CDSDSSPMAL FLKMIGPTHG QMTVTRLVNT 
      1117       1127       1137       1147 
LKEGKRLPCP PNCPDEVYQL MRKCWEFQPS NRTSFQNLIE 

GFEALL
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1035