1P4O

IGF1R (Insulin-like growth factor 1 receptor)
Group: TYR
Uniprot: IGF1R_HUMAN
Organism: Homo sapiens
Domain boundary: 999 - 1268
Resolu: 1.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGinter None in-out out-in No_ligand No_ligand 978 - 1285 0
B Inactive DFGinter None in-out out-in No_ligand No_ligand 977 - 1290 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       982        992       1002       1012 
masvNPEYFS AADVYVPDEW EVAREKITMS RELGQGSFGM 
      1022       1032       1042       1052 
VYEGVAKGVV KDEPETRVAI KTVNEAASMR ERIEFLNEAS 
      1062       1072       1082       1092 
VMKEFNCHHV VRLLGVVSQG QPTLVIMELM TRGDLKSYLR 
      1102       1112       1122       1132 
SLRPAMANNP VLAPPSLSKM IQMAGEIADG MAYLNANKFV 
      1142       1152       1162       1172 
HRDLAARNCM VAEDFTVKIG DFGMTRDIYE TDYYRKGGKG 
      1182       1192       1202       1212 
LLPVRWMSPE SLKDGVFTTY SDVWSFGVVL WEIATLAEQP 
      1222       1232       1242       1252 
YQGLSNEQVL RFVMEGGLLD KPDNCPDMLF ELMRMCWQYN 
      1262       1272       1282       1292 
PKMRPSFLEI ISSIKEEMEP GFREVSFYYS EENKLPEPee 

ld
Lower-case residues are disordered in structure.
Mutations: E1097A,E1099A
Phosphorylation: None