7FIC

AURKA (Aurora kinase A)
Group: CAMK
Uniprot: AURKA_HUMAN
Organism: Homo sapiens
Domain boundary: 133 - 383
Resolu: 2.32

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGinter None out-none none-out 5YZ Type1 127 - 391 11
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       136        146        156        166 
QWALEDFEIG RPLGKGKFGN VYLAREKQSK FILALKVLFK 
       176        186        196        206 
AQLEKAGVEH QLRREVEIQS HLRHPNILRL YGYFHDATRV 
       216        226        236        246 
YLILEYAPLG TVYRELQKLS KFDEQRTATY ITELANALSY 
       256        266        276        286 
CHSKRVIHRD IKPENLLLGS AGELKIADFG WSvhapssrr 
       296        306        316        326 
ttlAGTLDYL PPEMIEGRMH DEKVDLWSLG VLCYEFLVGK 
       336        346        356        366 
PPFEANTYQE TYKRISRVEF TFPDFVTEGA RDLISRLLKH 
       376        386 
NPSQRPMLRE VLEHPWITAN SSKPS
Lower-case residues are disordered in structure.
Mutations: C290A
Phosphorylation: None