4U3Z

MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4)
Group: STE
Uniprot: M4K4_HUMAN
Organism: Homo sapiens
Domain boundary: 25 - 289
Resolu: 2.09

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGinter None out-out out-out No_ligand No_ligand 17 - 311 0
B Inactive DFGout None out-out out-out No_ligand No_ligand 14 - 311 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         9         19         29         39 
gsandspaks lvdiDLSSLR DPAGIFELVE VvgngTYGQV 
        49         59         69         79 
YKGRHVKTGQ LAAIKVMDVT EDEEEEIKLE INMLKKYSHH 
        89         99        109        119 
RNIATYYGAF IKKSPPGHDD QLWLVMEFCG AGSITDLVKN 
       129        139        149        159 
TKGNTLKEDW IAYISREILR GLAHLHIHHV IHRDIKGQNV 
       169        179        189        199 
LLTENAEVKL VDFGVSAQLD REVGRRNTFI GTPYWMAPEV 
       209        219        229        239 
IACDENPDAT YDYRSDLWSC GITAIEMAEG APPLCDMHPM 
       249        259        269        279 
RALFLIPRNP PPRLKSKKWS KKFFSFIEGC LVKNYMQRPS 
       289        299        309        319 
TEQLLKHPFI RDQPNERQVR IQLKDHIDRT RKkrgekdet 
         - 
eyeysgseeg ns
Lower-case residues are disordered in structure.
Mutations: T181E
Phosphorylation: None