4JBQ

AURKA (Aurora kinase A)
Group: CAMK
Uniprot: AURKA_HUMAN
Organism: Homo sapiens
Domain boundary: 133 - 383
Resolu: 2.3

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGinter None out-out out-out VX6 Type1 126 - 391 9
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       132        142        152        162 
skkRQWALED FEIGRPLGKG KFGNVYLARE KQSKFILALK 
       172        182        192        202 
VLFKAQLEKA GVEHQLRREV EIQSHLRHPN ILRLYGYFHD 
       212        222        232        242 
ATRVYLILEY APLGTVYREL QKLSKFDEQR TATYITELAN 
       252        262        272        282 
ALSYCHSKRV IHRDIKPENL LLGSAGELKI ADFGWSVHap 
       292        302        312        322 
ssrrtdlCGT LDYLPPEMIE GRMHDEKVDL WSLGVLCYEF 
       332        342        352        362 
LVGKPPFEAN TYQETYKRIS RVEFTFPDFV TEGARDLISR 
       372        382        392 
LLKHNPSQRP MLREVLEHPW ITANSSKPSn cqnkesask
Lower-case residues are disordered in structure.
Mutations: T288D
Phosphorylation: None