6G78

RPS6KA6 (Ribosomal protein S6 kinase alpha-6)
Group: AGC
Uniprot: KS6A6_HUMAN
Organism: Homo sapiens
Domain boundary: 73 - 330
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGinter None none-none out-out ANP Type1 51 - 349 8
B Inactive DFGinter None none-none out-out ANP Type1 51 - 349 10
Representative sequence - Chain B
52 62 72 82
gplgsdegVV KEIPITHHVK EGYEKADPAQ FELLKVLGQG
92 102 112 122
SFGKVFLVRK KTGPDAGQLY AMKVLKKASL KVRDrvrtkm
132 142 152 162
erDILVEVNH PFIVKLHYAF QTEGKLYLIL DFLRGGDVFT
172 182 192 202
RLSKEVLFTE EDVKFYLAEL ALALDHLHQL GIVYRDLKPE
212 222 232 242
NILLDEIGHI KLTDFGLSKE SVdqekkaye fcGTVEYMAP
252 262 272 282
EVVNRRGHSQ SADWWSYGVL MFEMLTGTLP FQGKDRNETM
292 302 312 322
NMILKAKLGM PQFLSAEAQS LLRMLFKRNP ANRLGSEGVE
332 342
EIKRHLFFAN IDWDKLYKRE VQPPFKP
Lower-case residues are disordered in structure.
Mutations: S232E
Phosphorylation: None