Activity: Pseudo (pseudokinase)

Total number of chains: 249
Active chains: 0
Total number of genes: 28
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 109 43.8% 8BA3A
DFGin BLAminus 50 20.1% 9M6GA
DFGin BLBplus 31 12.4% 7JURB
DFGinter None 15 6.0% 9D5IA
DFGin BLBminus 13 5.2% 9QTUA
DFGin ABAminus 11 4.4% 1TKIA
None None 11 4.4% 7BL1CCC
DFGin BLAplus 3 1.2% 7JXUA
DFGout BBAminus 3 1.2% 6VG3A
DFGout None 2 0.8% 6O5ZB
DFGin BLBtrans 1 0.4% 9BCPB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK CASK CSKP_HUMAN 3MFRA 2.0 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3MFSA 2.1 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 4 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3MFUA 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 9M6GA 1.7 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 312 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 9M5YA 1.8 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 3 - 312 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3C0HA 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 5 - 304 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3C0HB 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 5 - 304 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3MFTA 2.2 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 6KMHA 2.4 Pseudo DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 318 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 6KMHB 2.4 Pseudo DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 319 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 8Y68A 2.2 Pseudo DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 326 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 8Y68B 2.2 Pseudo DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 326 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3TACA 2.2 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 316 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3C0GA 2.19 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3AM Type1 6 - 322 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3C0GB 2.19 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3AM Type1 5 - 324 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 3C0IA 1.85 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3AM Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OAIA 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V5W Type1 5 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OAIB 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V5W Type1 5 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OAIC 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V5W Type1 5 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OAID 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V5W Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OAJA 1.93 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6E Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OAJB 1.93 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6E Type1 6 - 302 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OAJC 1.93 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6E Type1 6 - 302 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OAJD 1.93 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6E Type1 6 - 302 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OAKA 2.23 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6B Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OAKB 2.23 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6B Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OAKC 2.23 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6B Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OAKD 2.23 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6B Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OALA 2.17 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V62 Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OALB 2.17 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V62 Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OALC 2.17 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V62 Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK CASK CSKP_HUMAN 7OALD 2.17 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V62 Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK
CAMK STK40 STK40_HUMAN 5L2QA 2.53 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 336 0 None None Serine/threonine-protein kinase 40
CAMK STK40 STK40_HUMAN 5L2QB 2.53 Pseudo DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 30 - 336 0 None None Serine/threonine-protein kinase 40
CAMK STK40 STK40_HUMAN 5L2QC 2.53 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 37 - 335 0 None None Serine/threonine-protein kinase 40
CAMK STK40 STK40_HUMAN 5L2QD 2.53 Pseudo DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 30 - 336 0 None None Serine/threonine-protein kinase 40
CAMK TRIB1 TRIB1_HUMAN 6DC0A 2.8 Pseudo DFGin‑ABAminus in-na in-out nonTYR APEdihe_aaiai APEdist_iioi No_ligand No_ligand 90 - 67 0 None None Tribbles homolog 1
CAMK TRIB1 TRIB1_HUMAN 6DC0B 2.8 Pseudo DFGin‑ABAminus in-na in-out nonTYR APEdihe_aaiai APEdist_iioi No_ligand No_ligand 90 - 74 0 None None Tribbles homolog 1
CAMK TRIB1 TRIB1_HUMAN 5CEKA 2.8 Pseudo DFGinter‑None out-na none-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 88 - 342 0 None None Tribbles homolog 1
CAMK TRIB1 TRIB1_HUMAN 5CEMA 2.1 Pseudo DFGinter‑None out-na none-out nonTYR APEdihe_aaiao APEdist_oooo No_ligand No_ligand 88 - 364 0 None None Tribbles homolog 1
CAMK TRIB2 TRIB2_HUMAN 7UPMA 2.7 Pseudo DFGin‑ABAminus in-na in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 55 - 312 0 None None Tribbles homolog 2
CAMK TTN TITIN_HUMAN 1TKIA 2.0 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32172 - 32492 0 None None Titin
CAMK TTN TITIN_HUMAN 1TKIB 2.0 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32172 - 32492 0 None None Titin
CAMK TTN TITIN_HUMAN 4JNWA 2.06 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32172 - 32491 0 None None Titin
CAMK TTN TITIN_HUMAN 4JNWB 2.06 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iooo No_ligand No_ligand 32172 - 32492 0 None None Titin
CAMK TTN TITIN_HUMAN 6YGNA 2.4 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32046 - 32594 0 None None Titin
CAMK TTN TITIN_HUMAN 6YGNB 2.4 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32046 - 32594 0 None None Titin
CK1 VRK3 VRK3_HUMAN 2JIIA 2.0 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 141 - 472 0 None None Serine/threonine-protein kinase VRK3
CK1 VRK3 VRK3_HUMAN 2JIIB 2.0 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 138 - 472 0 None None Serine/threonine-protein kinase VRK3
OTHER MLKL MLKL_HUMAN 6O5ZA 2.285 Pseudo DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 7JXUA 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 7JXUB 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 7MONA 2.23 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ZL1 Type1 191 - 469 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 4MWIA 1.7 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo PXN Allosteric 193 - 470 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 6BWKA 2.79 Pseudo DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 192 - 470 0 None T357E,S358E Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 7JW7A 2.63 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 8SLZA 2.3 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 469 0 TPO357,SEP358 None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 4M67A 1.9 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 469 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 6LK6A 2.41 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357A,S358A Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 6LK5A 2.5 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357E,S358D Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 5KO1A 2.16 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo 6UY Type1 192 - 470 0 None E366A,K367A Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 6O5ZB 2.285 Pseudo DFGout‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno LN4 Type2 190 - 467 0 None None Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 5KNJA 2.88 Pseudo None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6UX Type1 193 - 468 0 None E366A,K367A Mixed lineage kinase domain-like protein
OTHER MLKL MLKL_HUMAN 5KNJB 2.88 Pseudo None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6UX Type1 192 - 469 0 None E366A,K367A Mixed lineage kinase domain-like protein
OTHER PAN3 PAN3_HUMAN 9QTUA 4.6 Pseudo DFGin‑BLBminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 887 0 None None PAN2-PAN3 deadenylation complex subunit PAN3
OTHER PAN3 PAN3_HUMAN 9QTUB 4.6 Pseudo DFGin‑BLBminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 887 0 None None PAN2-PAN3 deadenylation complex subunit PAN3
OTHER PEAK1 PEAK1_HUMAN 6BHCA 2.3 Pseudo DFGin‑BLAminus out-na in-out nonTYR APEdihe_aaoai APEdist_nnno No_ligand No_ligand 1285 - 1743 0 None S1542T Inactive tyrosine-protein kinase PEAK1
OTHER PIK3R4 PI3R4_HUMAN 8SORA 3.96 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo ADP ATPlike 15 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 9MHFA 2.73 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 14 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 9MHGA 3.2 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 2 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 9C82A 6.84 Pseudo None‑None none-none out-out nonTYR APEdihe_aaono APEdist_oooo No_ligand No_ligand 64 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 7BL1CCC 9.8 Pseudo None‑None out-none out-out nonTYR APEdihe_aaono APEdist_oooo No_ligand No_ligand 12 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PIK3R4 PI3R4_HUMAN 9MHHA 4.5 Pseudo None‑None none-none out-out nonTYR APEdihe_aaono APEdist_oooo No_ligand No_ligand 16 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4
OTHER PRAG1 PRAG1_HUMAN 5VE6A 2.953 Pseudo None‑None none-na none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 944 - 1405 0 None None Inactive tyrosine-protein kinase PRAG1
OTHER RNASEL RN5A_HUMAN 4OAUC 2.6 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ADP ATPlike 25 - 719 0 None H672N 2-5A-dependent ribonuclease
OTHER RNASEL RN5A_HUMAN 4OAVB 2.1 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ACP ATPlike 24 - 717 0 None H672N 2-5A-dependent ribonuclease
OTHER RNASEL RN5A_HUMAN 4OAVD 2.1 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ACP ATPlike 26 - 719 0 None H672N 2-5A-dependent ribonuclease
OTHER ULK4 ULK4_HUMAN 6TSZU 1.9 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaiii APEdist_iooi AGS ATPlike 2 - 285 0 None None Serine/threonine-protein kinase ULK4
OTHER ULK4 ULK4_HUMAN 6U5LA 1.75 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaioi APEdist_iooi 3RJ Type1 1 - 285 0 None K172A,K173A Serine/threonine-protein kinase ULK4
RGC GUCY2C GUC2C_HUMAN 8FX4D 3.9 Pseudo None‑None none-none none-out nonTYR APEdihe_aaiao APEdist_iioo No_ligand No_ligand 550 - 755 0 None None Guanylyl cyclase C
RGC NPR1 ANPRA_HUMAN 9BCOA 4.4 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaini APEdist_oooo ATP ATPlike 498 - 1053 0 None None Atrial natriuretic peptide receptor 1
RGC NPR1 ANPRA_HUMAN 9BCOB 4.4 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoni APEdist_oooo ATP ATPlike 501 - 1053 0 None None Atrial natriuretic peptide receptor 1
RGC NPR1 ANPRA_HUMAN 9BCPA 4.1 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 505 - 842 0 None None Atrial natriuretic peptide receptor 1
RGC NPR1 ANPRA_HUMAN 9BCPB 4.1 Pseudo DFGin‑BLBtrans out-none out-out nonTYR APEdihe_aaoao APEdist_oooo ATP ATPlike 503 - 841 0 None None Atrial natriuretic peptide receptor 1
RGC NPR1 ANPRA_HUMAN 9BCSA 4.4 Pseudo DFGin‑None out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 503 - 1055 0 None None Atrial natriuretic peptide receptor 1
RGC NPR1 ANPRA_HUMAN 9BCSB 4.4 Pseudo None‑None out-none out-out nonTYR APEdihe_aaoni APEdist_oooo ATP ATPlike 505 - 1055 0 None None Atrial natriuretic peptide receptor 1
STE STRADA STRAA_HUMAN 2WTKB 2.65 Pseudo DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaoai APEdist_iooo ANP ATPlike 61 - 431 0 None None STE20-related kinase adapter protein alpha
STE STRADA STRAA_HUMAN 2WTKE 2.65 Pseudo DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaoai APEdist_iooo ANP ATPlike 60 - 431 0 None None STE20-related kinase adapter protein alpha
STE STRADA STRAA_HUMAN 3GNIB 2.35 Pseudo DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaoai APEdist_iooo ATP ATPlike 60 - 431 0 None None STE20-related kinase adapter protein alpha
STE STRADA STRAA_HUMAN 8VSUB 2.86 Pseudo DFGin‑None out-none in-out nonTYR APEdihe_aaoai APEdist_iooo ADP ATPlike 60 - 401 0 None None STE20-related kinase adapter protein alpha
TKL ILK ILK_HUMAN 9D5IA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo ATP ATPlike 182 - 452 0 None R225A,C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 3KMWA 2.0 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo ATP ATPlike 185 - 452 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 3REPA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo ATP ATPlike 185 - 452 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 3KMUA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo No_ligand No_ligand 185 - 451 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 6MIBA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo No_ligand No_ligand 183 - 452 0 None L207W Scaffold protein ILK
TKL ILK ILK_HUMAN 9D5HA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo IRE Type1 182 - 452 0 None C346S,R371Q,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 9D5FA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo DB8 Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 9D5GAAAA 1.55 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo A1A2V Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 9D5PA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo AQ4 Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK
TKL ILK ILK_HUMAN 9D5EA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo IRE, IRE Type1, Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK
TKL IRAK3 IRAK3_HUMAN 6ZIWI 2.18 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 153 - 451 0 None None Interleukin-1 receptor-associated kinase 3
TKL IRAK3 IRAK3_HUMAN 6RUUA 2.95 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 153 - 450 0 None None Interleukin-1 receptor-associated kinase 3
TKL IRAK3 IRAK3_HUMAN 6RUUB 2.95 Pseudo DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoai APEdist_iooo No_ligand No_ligand 152 - 452 0 None None Interleukin-1 receptor-associated kinase 3
TKL IRAK3 IRAK3_HUMAN 6RUUC 2.95 Pseudo None‑None out-none none-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 179 - 454 0 None None Interleukin-1 receptor-associated kinase 3
TKL KSR1 KSR1_HUMAN 9AXHC 2.81 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 614 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 9AXHD 2.81 Pseudo DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 613 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUWB 2.88 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUXA 3.34 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUYB 3.096 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JUZA 3.21 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JV0A 3.63 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR1 KSR1_HUMAN 7JV1D 3.62 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1
TKL KSR2 KSR2_HUMAN 2Y4IB 3.46 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 653 - 931 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUQB 3.22 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ADP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JURB 2.82 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUSB 2.99 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUTB 3.09 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUUB 3.19 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7JUVB 3.36 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 7UMBB 3.231 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2
TKL KSR2 KSR2_HUMAN 5KKRB 3.509 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo 6U7 Type1.5_Back 650 - 932 0 None None Kinase suppressor of Ras 2
TYR ERBB3 ERBB3_HUMAN 3KEXA 2.797 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 698 - 994 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 3KEXB 2.797 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 698 - 988 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIWA 3.1 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIWC 3.1 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 3LMGA 2.8 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 3LMGB 2.8 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIYA 2.981 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIYC 2.981 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIXA 3.1 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIXC 3.1 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 6OP9A 2.501 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oiiai APEdist_aaai DB8 Type1 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3
TYR JAK1-1 JAK1_HUMAN 4L01A 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 565 - 850 0 None V658F Tyrosine-protein kinase JAK1
TYR JAK1-1 JAK1_HUMAN 4L01B 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 565 - 849 0 None V658F Tyrosine-protein kinase JAK1
TYR JAK1-1 JAK1_HUMAN 4L00A 1.8 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 564 - 850 0 None None Tyrosine-protein kinase JAK1
TYR JAK1-1 JAK1_HUMAN 4L00B 1.8 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 565 - 850 0 None None Tyrosine-protein kinase JAK1
TYR JAK2-1 JAK2_HUMAN 5I4NA 1.54 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 537 - 809 0 None E596A,V617F,W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 4FVRA 2.0 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 536 - 809 0 None V617F,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 4FVQA 1.75 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C08A 2.2 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 537 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C08B 2.2 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 536 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BA4B 2.1 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 4FVPA 2.01 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C09A 1.9 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 538 - 809 0 None I559F,W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6G3CA 1.6 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao EKT Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6G3CB 1.6 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao EKT Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6D2IA 3.192 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 35R Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6D2IB 3.192 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 35R Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8B8NA 2.0 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao AQG Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8B8UA 1.5 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao T7I Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8B8UB 1.5 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao T7I Type1 538 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BA2A 1.5 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao Q9X Type1 536 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BA4A 2.1 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao Q8U Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7F7WA 1.83 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao 36H Type1 536 - 810 0 None None Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7F7WB 1.83 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao 36H Type1 536 - 810 0 None None Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8B99A 1.6 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao SKE Type1 536 - 809 0 None W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8B9EA 1.5 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao Q7F Type1 536 - 809 0 None W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BABA 1.55 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao Q8N Type1 536 - 809 0 None W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BAKA 1.65 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao AD5 Type1 536 - 809 0 None W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C0AA 1.7 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao T7I Type1 536 - 809 0 None W659A,R683S,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C0AB 1.7 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao T7I Type1 536 - 808 0 None W659A,R683S,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5WIJA 2.04 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AQG Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5WIKB 2.6 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao 584 Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5WILA 2.2 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao YDJ Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5WIMA 2.55 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao 35R Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5WINA 2.38 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao SKE Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5USZA 2.103 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao SKE Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT0A 2.102 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 35R Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT1A 1.95 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 7DZ Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT2A 1.75 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 3YT Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT3A 1.501 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao IK1 Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT4A 2.0 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao DQX Type1 537 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT5A 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 2HB Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 5UT6A 1.645 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 8MY Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6BRWA 2.031 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 5BS Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6BS0A 1.541 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao E4V Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6BSSA 2.1 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 4SP Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6M9HA 1.79 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao J9D Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6OAVA 1.939 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao M3A Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6OBBA 1.904 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao M3Y Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6OBFA 1.71 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao M4G Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6OBLA 2.061 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao M4P Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6OCCA 2.03 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao M57 Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 6XJKA 2.024 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao V4D Type1 539 - 807 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7JYOA 2.161 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao VPS Type1 539 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7JYQA 1.859 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao VPJ Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7SZWA 1.906 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao DVY Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7T0PA 2.04 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao E3W Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7T0PB 2.04 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao E3W Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7T1TA 2.08 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao E8I Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8B9HA 1.5 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao Q7F Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BA3A 1.4 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao Q8U Type1 536 - 812 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8EX0A 1.85 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AQG Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8EX1A 1.5 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AD5 Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8EX2A 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao Q2Q Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 9ND5A 2.4 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao A1BXA Type1 536 - 809 0 None None Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 9ND3A 1.62 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao A1BW6 Type1 536 - 808 0 None None Tyrosine-protein kinase JAK2
TYR PTK7 PTK7_HUMAN 6VG3A 1.95 Pseudo DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 788 - 1064 0 None None Inactive tyrosine-protein kinase 7
TYR PTK7 PTK7_HUMAN 6VG3B 1.95 Pseudo DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 788 - 1066 0 None None Inactive tyrosine-protein kinase 7
TYR PTK7 PTK7_HUMAN 6VG3C 1.95 Pseudo DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 789 - 1063 0 None None Inactive tyrosine-protein kinase 7
TYR ROR1 ROR1_HUMAN 6TU9A 1.94 Pseudo None‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type1 460 - 749 0 None None Inactive tyrosine-protein kinase transmembrane receptor ROR1
TYR ROR1 ROR1_HUMAN 6TU9B 1.94 Pseudo None‑None in-in none-in TYR APEdihe_iiiai APEdist_aaai 0LI Type1 465 - 750 0 None None Inactive tyrosine-protein kinase transmembrane receptor ROR1
TYR ROR2 ROR2_HUMAN 3ZZWA 2.9 Pseudo DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 466 - 750 0 None None Tyrosine-protein kinase transmembrane receptor ROR2
TYR ROR2 ROR2_HUMAN 4GT4A 2.406 Pseudo DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 464 - 751 0 None None Tyrosine-protein kinase transmembrane receptor ROR2
TYR ROR2 ROR2_HUMAN 4GT4B 2.406 Pseudo DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 464 - 752 0 None None Tyrosine-protein kinase transmembrane receptor ROR2
TYR ROR2 ROR2_HUMAN 3ZZWB 2.9 Pseudo DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 466 - 750 0 None None Tyrosine-protein kinase transmembrane receptor ROR2
TYR TYK2-12 TYK2_HUMAN 4OLIA 2.8 Pseudo DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 2TT, 2TT Allosteric, Type1 579 - 1177 0 None D1023N Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 5C03A 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AGS ATPlike 579 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 5C03B 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AGS ATPlike 580 - 870 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 7AX4A 2.12 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao NM7 Type1 579 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 7AX4B 2.12 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao NM7 Type1 579 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8S98A 1.87 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZRU Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8S98B 1.87 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZRU Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8S98C 1.87 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZRU Type1 578 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8S99A 1.71 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZS3 Type1 578 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8S99B 1.71 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZS3 Type1 579 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8S99C 1.71 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZS3 Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8S9AA 1.83 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZSB Type1 577 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8S9AB 1.83 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZSB Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8S9AC 1.83 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZSB Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 5TKDA 1.92 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 7GL Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 5TKDB 1.92 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 7GL Type1 581 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 3ZONA 2.15 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao IK1 Type1 577 - 870 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZRA 2.56 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao LAJ Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZRB 2.56 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao LAJ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 4WOVA 1.8 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 3SM Type1 580 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 4WOVB 1.8 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 3SM Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NSLA 2.15 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao KZJ Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NSLB 2.15 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao KZJ Type1 581 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZEA 1.96 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao L8Y Type1 581 - 863 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZEB 1.96 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao L8Y Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZFA 2.39 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao L91 Type1 580 - 865 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZFB 2.39 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao L91 Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZHA 2.73 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao L9A Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZHB 2.73 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao L9A Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZPA 2.35 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao LB7 Type1 580 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZPB 2.35 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao LB7 Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZQA 2.11 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao LB4 Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 6NZQB 2.11 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao LB4 Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 7K7OA 2.82 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao VZJ Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 7K7OB 2.82 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao VZJ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 7K7QA 2.27 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao VZG Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 7K7QB 2.27 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao VZG Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8TB5A 2.32 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZOQ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8TB5B 2.32 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZOQ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8TB6A 1.96 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZOI Type1 572 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8TB6B 1.96 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZOI Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 5C01A 2.15 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao UNL Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 5C01B 2.15 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao UNL Type1 579 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2

Activity: Pseudo (pseudokinase)

Total number of chains: 325
Active chains: 0
Total number of genes: 42
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 140 43.1% 8BA3A
DFGin BLAminus 60 18.5% 9M6GA
DFGin BLBplus 32 9.8% 7JURB
DFGin BLBminus 22 6.8% 9QTUA
None None 21 6.5% 7BL1CCC
DFGin ABAminus 16 4.9% 1TKIA
DFGinter None 15 4.6% 9D5IA
DFGout None 7 2.2% 4I93A
DFGout BBAminus 6 1.8% 6VG3A
DFGin BLAplus 5 1.5% 7JXUA
DFGin BLBtrans 1 0.3% 9BCPB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER BIR2 BIR2_ARATH 4L68A 2.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiai APEdist_nioi PDO Allosteric 272 - 600 0 None None Inactive LRR receptor-like serine/threonine-protein kinase BIR2 Arabidopsis thaliana
OTHER BIR2 BIR2_ARATH 4L68B 2.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 271 - 600 0 None None Inactive LRR receptor-like serine/threonine-protein kinase BIR2 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I94A 1.8 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo ANP ATPlike 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I94B 1.8 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo ANP ATPlike 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I92A 1.6 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iooo No_ligand No_ligand 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I93A 1.5 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo No_ligand No_ligand 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I93B 1.5 Pseudo DFGout‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAA 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAB 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAC 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAD 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4A 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4B 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4C 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4D 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER STKLD1 F1MSZ0_BOVIN 9FQRXR 5.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoai APEdist_oooo No_ligand No_ligand 1 - 610 0 None None Serine/threonine kinase like domain containing 1 Bos taurus
OTHER PAN3 PAN3_CHATD 4CYIA 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIB 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 213 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIC 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYID 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 214 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIE 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIF 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 213 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIG 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 212 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIH 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJA 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 630 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJB 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJC 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 210 - 632 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJD 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER POMK SG196_DANRE 5GZAA 2.0 Pseudo DFGin‑None none-na in-out nonTYR APEdihe_aaioo APEdist_iioo ADP, ZZ1 ATPlike, Allosteric 53 - 342 0 None None Protein O-mannose kinase Danio rerio
CAMK OBSCN-1 OBSCN_DROME 8AK3A 1.9 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 3186 - 3477 0 None None Protein Obscurin Drosophila melanogaster
CAMK OBSCN-1 OBSCN_DROME 8AK2A 1.75 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 3186 - 3472 0 None None Protein Obscurin Drosophila melanogaster
OTHER PAN3 PAN3_DROME 4BWPA 3.6 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AN2 ATPlike 379 - 787 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Drosophila melanogaster
OTHER PAN3 PAN3_DROME 4BWPB 3.6 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AN2 ATPlike 379 - 787 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Drosophila melanogaster
OTHER MLKL F6S337_HORSE 6VC0A 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 536 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER MLKL F6S337_HORSE 6VC0B 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 258 - 537 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER MLKL F6S337_HORSE 6VC0C 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 541 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
CAMK CASK CSKP_HUMAN 3MFRA 2.0 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3MFSA 2.1 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 4 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3MFUA 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 9M6GA 1.7 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 5 - 312 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 9M5YA 1.8 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 3 - 312 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3C0HA 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 5 - 304 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3C0HB 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AMP ATPlike 5 - 304 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3MFTA 2.2 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 306 0 None P22A,H145E,C146N,G162D Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 6KMHA 2.4 Pseudo DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 318 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 6KMHB 2.4 Pseudo DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 319 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 8Y68A 2.2 Pseudo DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 326 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 8Y68B 2.2 Pseudo DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 5 - 326 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3TACA 2.2 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 316 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3C0GA 2.19 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3AM Type1 6 - 322 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3C0GB 2.19 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3AM Type1 5 - 324 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 3C0IA 1.85 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3AM Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OAIA 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V5W Type1 5 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OAIB 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V5W Type1 5 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OAIC 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V5W Type1 5 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OAID 2.3 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V5W Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OAJA 1.93 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6E Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OAJB 1.93 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6E Type1 6 - 302 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OAJC 1.93 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6E Type1 6 - 302 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OAJD 1.93 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6E Type1 6 - 302 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OAKA 2.23 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6B Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OAKB 2.23 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6B Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OAKC 2.23 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6B Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OAKD 2.23 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V6B Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OALA 2.17 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V62 Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OALB 2.17 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V62 Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OALC 2.17 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V62 Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK CASK CSKP_HUMAN 7OALD 2.17 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii V62 Type1 6 - 303 0 None None Peripheral plasma membrane protein CASK Homo sapiens
CAMK STK40 STK40_HUMAN 5L2QA 2.53 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 336 0 None None Serine/threonine-protein kinase 40 Homo sapiens
CAMK STK40 STK40_HUMAN 5L2QB 2.53 Pseudo DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 30 - 336 0 None None Serine/threonine-protein kinase 40 Homo sapiens
CAMK STK40 STK40_HUMAN 5L2QC 2.53 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 37 - 335 0 None None Serine/threonine-protein kinase 40 Homo sapiens
CAMK STK40 STK40_HUMAN 5L2QD 2.53 Pseudo DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii No_ligand No_ligand 30 - 336 0 None None Serine/threonine-protein kinase 40 Homo sapiens
CAMK TRIB1 TRIB1_HUMAN 6DC0A 2.8 Pseudo DFGin‑ABAminus in-na in-out nonTYR APEdihe_aaiai APEdist_iioi No_ligand No_ligand 90 - 67 0 None None Tribbles homolog 1 Homo sapiens
CAMK TRIB1 TRIB1_HUMAN 6DC0B 2.8 Pseudo DFGin‑ABAminus in-na in-out nonTYR APEdihe_aaiai APEdist_iioi No_ligand No_ligand 90 - 74 0 None None Tribbles homolog 1 Homo sapiens
CAMK TRIB1 TRIB1_HUMAN 5CEKA 2.8 Pseudo DFGinter‑None out-na none-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 88 - 342 0 None None Tribbles homolog 1 Homo sapiens
CAMK TRIB1 TRIB1_HUMAN 5CEMA 2.1 Pseudo DFGinter‑None out-na none-out nonTYR APEdihe_aaiao APEdist_oooo No_ligand No_ligand 88 - 364 0 None None Tribbles homolog 1 Homo sapiens
CAMK TRIB2 TRIB2_HUMAN 7UPMA 2.7 Pseudo DFGin‑ABAminus in-na in-out nonTYR APEdihe_aaiai APEdist_iooi No_ligand No_ligand 55 - 312 0 None None Tribbles homolog 2 Homo sapiens
CAMK TTN TITIN_HUMAN 1TKIA 2.0 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32172 - 32492 0 None None Titin Homo sapiens
CAMK TTN TITIN_HUMAN 1TKIB 2.0 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32172 - 32492 0 None None Titin Homo sapiens
CAMK TTN TITIN_HUMAN 4JNWA 2.06 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32172 - 32491 0 None None Titin Homo sapiens
CAMK TTN TITIN_HUMAN 4JNWB 2.06 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iooo No_ligand No_ligand 32172 - 32492 0 None None Titin Homo sapiens
CAMK TTN TITIN_HUMAN 6YGNA 2.4 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32046 - 32594 0 None None Titin Homo sapiens
CAMK TTN TITIN_HUMAN 6YGNB 2.4 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaini APEdist_iioo No_ligand No_ligand 32046 - 32594 0 None None Titin Homo sapiens
CK1 VRK3 VRK3_HUMAN 2JIIA 2.0 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 141 - 472 0 None None Serine/threonine-protein kinase VRK3 Homo sapiens
CK1 VRK3 VRK3_HUMAN 2JIIB 2.0 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 138 - 472 0 None None Serine/threonine-protein kinase VRK3 Homo sapiens
OTHER MLKL MLKL_HUMAN 6O5ZA 2.285 Pseudo DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 7JXUA 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 7JXUB 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 7MONA 2.23 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ZL1 Type1 191 - 469 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 4MWIA 1.7 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo PXN Allosteric 193 - 470 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 6BWKA 2.79 Pseudo DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 192 - 470 0 None T357E,S358E Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 7JW7A 2.63 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 8SLZA 2.3 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 469 0 TPO357,SEP358 None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 4M67A 1.9 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 469 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 6LK6A 2.41 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357A,S358A Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 6LK5A 2.5 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357E,S358D Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 5KO1A 2.16 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo 6UY Type1 192 - 470 0 None E366A,K367A Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 6O5ZB 2.285 Pseudo DFGout‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno LN4 Type2 190 - 467 0 None None Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 5KNJA 2.88 Pseudo None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6UX Type1 193 - 468 0 None E366A,K367A Mixed lineage kinase domain-like protein Homo sapiens
OTHER MLKL MLKL_HUMAN 5KNJB 2.88 Pseudo None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6UX Type1 192 - 469 0 None E366A,K367A Mixed lineage kinase domain-like protein Homo sapiens
OTHER PAN3 PAN3_HUMAN 9QTUA 4.6 Pseudo DFGin‑BLBminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 887 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Homo sapiens
OTHER PAN3 PAN3_HUMAN 9QTUB 4.6 Pseudo DFGin‑BLBminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 887 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Homo sapiens
OTHER PEAK1 PEAK1_HUMAN 6BHCA 2.3 Pseudo DFGin‑BLAminus out-na in-out nonTYR APEdihe_aaoai APEdist_nnno No_ligand No_ligand 1285 - 1743 0 None S1542T Inactive tyrosine-protein kinase PEAK1 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 8SORA 3.96 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo ADP ATPlike 15 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 9MHFA 2.73 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 14 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 9MHGA 3.2 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 2 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 9C82A 6.84 Pseudo None‑None none-none out-out nonTYR APEdihe_aaono APEdist_oooo No_ligand No_ligand 64 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 7BL1CCC 9.8 Pseudo None‑None out-none out-out nonTYR APEdihe_aaono APEdist_oooo No_ligand No_ligand 12 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PIK3R4 PI3R4_HUMAN 9MHHA 4.5 Pseudo None‑None none-none out-out nonTYR APEdihe_aaono APEdist_oooo No_ligand No_ligand 16 - 1358 0 None None Phosphoinositide 3-kinase regulatory subunit 4 Homo sapiens
OTHER PRAG1 PRAG1_HUMAN 5VE6A 2.953 Pseudo None‑None none-na none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 944 - 1405 0 None None Inactive tyrosine-protein kinase PRAG1 Homo sapiens
OTHER RNASEL RN5A_HUMAN 4OAUC 2.6 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ADP ATPlike 25 - 719 0 None H672N 2-5A-dependent ribonuclease Homo sapiens
OTHER RNASEL RN5A_HUMAN 4OAVB 2.1 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ACP ATPlike 24 - 717 0 None H672N 2-5A-dependent ribonuclease Homo sapiens
OTHER RNASEL RN5A_HUMAN 4OAVD 2.1 Pseudo DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa ACP ATPlike 26 - 719 0 None H672N 2-5A-dependent ribonuclease Homo sapiens
OTHER ULK4 ULK4_HUMAN 6TSZU 1.9 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaiii APEdist_iooi AGS ATPlike 2 - 285 0 None None Serine/threonine-protein kinase ULK4 Homo sapiens
OTHER ULK4 ULK4_HUMAN 6U5LA 1.75 Pseudo DFGin‑ABAminus out-na in-out nonTYR APEdihe_aaioi APEdist_iooi 3RJ Type1 1 - 285 0 None K172A,K173A Serine/threonine-protein kinase ULK4 Homo sapiens
RGC GUCY2C GUC2C_HUMAN 8FX4D 3.9 Pseudo None‑None none-none none-out nonTYR APEdihe_aaiao APEdist_iioo No_ligand No_ligand 550 - 755 0 None None Guanylyl cyclase C Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCOA 4.4 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaini APEdist_oooo ATP ATPlike 498 - 1053 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCOB 4.4 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoni APEdist_oooo ATP ATPlike 501 - 1053 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCPA 4.1 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 505 - 842 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCPB 4.1 Pseudo DFGin‑BLBtrans out-none out-out nonTYR APEdihe_aaoao APEdist_oooo ATP ATPlike 503 - 841 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCSA 4.4 Pseudo DFGin‑None out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 503 - 1055 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
RGC NPR1 ANPRA_HUMAN 9BCSB 4.4 Pseudo None‑None out-none out-out nonTYR APEdihe_aaoni APEdist_oooo ATP ATPlike 505 - 1055 0 None None Atrial natriuretic peptide receptor 1 Homo sapiens
STE STRADA STRAA_HUMAN 2WTKB 2.65 Pseudo DFGin‑BLAminus out-none in-out nonTYR APEdihe_aaoai APEdist_iooo ANP ATPlike 61 - 431 0 None None STE20-related kinase adapter protein alpha Homo sapiens
STE STRADA STRAA_HUMAN 2WTKE 2.65 Pseudo DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaoai APEdist_iooo ANP ATPlike 60 - 431 0 None None STE20-related kinase adapter protein alpha Homo sapiens
STE STRADA STRAA_HUMAN 3GNIB 2.35 Pseudo DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaoai APEdist_iooo ATP ATPlike 60 - 431 0 None None STE20-related kinase adapter protein alpha Homo sapiens
STE STRADA STRAA_HUMAN 8VSUB 2.86 Pseudo DFGin‑None out-none in-out nonTYR APEdihe_aaoai APEdist_iooo ADP ATPlike 60 - 401 0 None None STE20-related kinase adapter protein alpha Homo sapiens
TKL ILK ILK_HUMAN 9D5IA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo ATP ATPlike 182 - 452 0 None R225A,C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 3KMWA 2.0 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo ATP ATPlike 185 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 3REPA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo ATP ATPlike 185 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 3KMUA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo No_ligand No_ligand 185 - 451 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 6MIBA 1.8 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo No_ligand No_ligand 183 - 452 0 None L207W Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 9D5HA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo IRE Type1 182 - 452 0 None C346S,R371Q,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 9D5FA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oooo DB8 Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 9D5GAAAA 1.55 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo A1A2V Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 9D5PA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo AQ4 Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL ILK ILK_HUMAN 9D5EA 1.5 Pseudo DFGinter‑None out-out out-out nonTYR APEdihe_aaini APEdist_oioo IRE, IRE Type1, Type1 182 - 452 0 None C346S,C422S Scaffold protein ILK Homo sapiens
TKL IRAK3 IRAK3_HUMAN 6ZIWI 2.18 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn AGS ATPlike 153 - 451 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens
TKL IRAK3 IRAK3_HUMAN 6RUUA 2.95 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aanni APEdist_nnnn No_ligand No_ligand 153 - 450 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens
TKL IRAK3 IRAK3_HUMAN 6RUUB 2.95 Pseudo DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoai APEdist_iooo No_ligand No_ligand 152 - 452 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens
TKL IRAK3 IRAK3_HUMAN 6RUUC 2.95 Pseudo None‑None out-none none-out nonTYR APEdihe_aaoni APEdist_nnno No_ligand No_ligand 179 - 454 0 None None Interleukin-1 receptor-associated kinase 3 Homo sapiens
TKL KSR1 KSR1_HUMAN 9AXHC 2.81 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 614 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 9AXHD 2.81 Pseudo DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 613 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUWB 2.88 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUXA 3.34 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUYB 3.096 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JUZA 3.21 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JV0A 3.63 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 601 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR1 KSR1_HUMAN 7JV1D 3.62 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 600 - 881 0 None None Kinase suppressor of Ras 1 Homo sapiens
TKL KSR2 KSR2_HUMAN 2Y4IB 3.46 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ATP ATPlike 653 - 931 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUQB 3.22 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ADP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JURB 2.82 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUSB 2.99 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUTB 3.09 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUUB 3.19 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7JUVB 3.36 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 7UMBB 3.231 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo ANP ATPlike 652 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TKL KSR2 KSR2_HUMAN 5KKRB 3.509 Pseudo DFGin‑BLBplus out-none out-out nonTYR APEdihe_aaoai APEdist_oooo 6U7 Type1.5_Back 650 - 932 0 None None Kinase suppressor of Ras 2 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 3KEXA 2.797 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 698 - 994 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 3KEXB 2.797 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 698 - 988 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIWA 3.1 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIWC 3.1 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 3LMGA 2.8 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_nnoai APEdist_aaao ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 3LMGB 2.8 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 978 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIYA 2.981 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIYC 2.981 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None E928G Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIXA 3.1 Pseudo DFGin‑BLBplus out-na out-none TYR APEdihe_nnnai APEdist_aaan ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 4RIXC 3.1 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oioai APEdist_aaao ANP ATPlike 699 - 979 0 None Q809R Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR ERBB3 ERBB3_HUMAN 6OP9A 2.501 Pseudo DFGin‑BLBplus out-na out-out TYR APEdihe_oiiai APEdist_aaai DB8 Type1 699 - 979 0 None None Receptor tyrosine-protein kinase erbB-3 Homo sapiens
TYR JAK1-1 JAK1_HUMAN 4L01A 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 565 - 850 0 None V658F Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-1 JAK1_HUMAN 4L01B 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 565 - 849 0 None V658F Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-1 JAK1_HUMAN 4L00A 1.8 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 564 - 850 0 None None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-1 JAK1_HUMAN 4L00B 1.8 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 565 - 850 0 None None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5I4NA 1.54 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 537 - 809 0 None E596A,V617F,W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 4FVRA 2.0 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 536 - 809 0 None V617F,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 4FVQA 1.75 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8C08A 2.2 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 537 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8C08B 2.2 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao ATP ATPlike 536 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8BA4B 2.1 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 4FVPA 2.01 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8C09A 1.9 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao No_ligand No_ligand 538 - 809 0 None I559F,W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6G3CA 1.6 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao EKT Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6G3CB 1.6 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao EKT Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6D2IA 3.192 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 35R Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6D2IB 3.192 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 35R Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8B8NA 2.0 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao AQG Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8B8UA 1.5 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao T7I Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8B8UB 1.5 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao T7I Type1 538 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8BA2A 1.5 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao Q9X Type1 536 - 810 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8BA4A 2.1 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao Q8U Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 7F7WA 1.83 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao 36H Type1 536 - 810 0 None None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 7F7WB 1.83 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao 36H Type1 536 - 810 0 None None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8B99A 1.6 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao SKE Type1 536 - 809 0 None W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8B9EA 1.5 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao Q7F Type1 536 - 809 0 None W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8BABA 1.55 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao Q8N Type1 536 - 809 0 None W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8BAKA 1.65 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao AD5 Type1 536 - 809 0 None W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8C0AA 1.7 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao T7I Type1 536 - 809 0 None W659A,R683S,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8C0AB 1.7 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao T7I Type1 536 - 808 0 None W659A,R683S,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5WIJA 2.04 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AQG Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5WIKB 2.6 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao 584 Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5WILA 2.2 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao YDJ Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5WIMA 2.55 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao 35R Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5WINA 2.38 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao SKE Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5USZA 2.103 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao SKE Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5UT0A 2.102 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 35R Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5UT1A 1.95 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 7DZ Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5UT2A 1.75 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 3YT Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5UT3A 1.501 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao IK1 Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5UT4A 2.0 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao DQX Type1 537 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5UT5A 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 2HB Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 5UT6A 1.645 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 8MY Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6BRWA 2.031 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 5BS Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6BS0A 1.541 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao E4V Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6BSSA 2.1 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 4SP Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6M9HA 1.79 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao J9D Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6OAVA 1.939 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao M3A Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6OBBA 1.904 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao M3Y Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6OBFA 1.71 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao M4G Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6OBLA 2.061 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao M4P Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6OCCA 2.03 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao M57 Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 6XJKA 2.024 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao V4D Type1 539 - 807 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 7JYOA 2.161 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao VPS Type1 539 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 7JYQA 1.859 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao VPJ Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 7SZWA 1.906 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao DVY Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 7T0PA 2.04 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao E3W Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 7T0PB 2.04 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao E3W Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 7T1TA 2.08 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao E8I Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8B9HA 1.5 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao Q7F Type1 536 - 809 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8BA3A 1.4 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao Q8U Type1 536 - 812 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8EX0A 1.85 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AQG Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8EX1A 1.5 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AD5 Type1 537 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 8EX2A 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao Q2Q Type1 536 - 808 0 None W659A,W777A,F794H Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 9ND5A 2.4 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao A1BXA Type1 536 - 809 0 None None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-1 JAK2_HUMAN 9ND3A 1.62 Pseudo DFGin‑None out-na out-out TYR APEdihe_oooao APEdist_aaao A1BW6 Type1 536 - 808 0 None None Tyrosine-protein kinase JAK2 Homo sapiens
TYR PTK7 PTK7_HUMAN 6VG3A 1.95 Pseudo DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 788 - 1064 0 None None Inactive tyrosine-protein kinase 7 Homo sapiens
TYR PTK7 PTK7_HUMAN 6VG3B 1.95 Pseudo DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 788 - 1066 0 None None Inactive tyrosine-protein kinase 7 Homo sapiens
TYR PTK7 PTK7_HUMAN 6VG3C 1.95 Pseudo DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 789 - 1063 0 None None Inactive tyrosine-protein kinase 7 Homo sapiens
TYR ROR1 ROR1_HUMAN 6TU9A 1.94 Pseudo None‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type1 460 - 749 0 None None Inactive tyrosine-protein kinase transmembrane receptor ROR1 Homo sapiens
TYR ROR1 ROR1_HUMAN 6TU9B 1.94 Pseudo None‑None in-in none-in TYR APEdihe_iiiai APEdist_aaai 0LI Type1 465 - 750 0 None None Inactive tyrosine-protein kinase transmembrane receptor ROR1 Homo sapiens
TYR ROR2 ROR2_HUMAN 3ZZWA 2.9 Pseudo DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 466 - 750 0 None None Tyrosine-protein kinase transmembrane receptor ROR2 Homo sapiens
TYR ROR2 ROR2_HUMAN 4GT4A 2.406 Pseudo DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 464 - 751 0 None None Tyrosine-protein kinase transmembrane receptor ROR2 Homo sapiens
TYR ROR2 ROR2_HUMAN 4GT4B 2.406 Pseudo DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 464 - 752 0 None None Tyrosine-protein kinase transmembrane receptor ROR2 Homo sapiens
TYR ROR2 ROR2_HUMAN 3ZZWB 2.9 Pseudo DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 466 - 750 0 None None Tyrosine-protein kinase transmembrane receptor ROR2 Homo sapiens
TYR TYK2-12 TYK2_HUMAN 4OLIA 2.8 Pseudo DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 2TT, 2TT Allosteric, Type1 579 - 1177 0 None D1023N Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 5C03A 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AGS ATPlike 579 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 5C03B 1.9 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao AGS ATPlike 580 - 870 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 7AX4A 2.12 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao NM7 Type1 579 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 7AX4B 2.12 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao NM7 Type1 579 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8S98A 1.87 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZRU Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8S98B 1.87 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZRU Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8S98C 1.87 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZRU Type1 578 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8S99A 1.71 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZS3 Type1 578 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8S99B 1.71 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZS3 Type1 579 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8S99C 1.71 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZS3 Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8S9AA 1.83 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZSB Type1 577 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8S9AB 1.83 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZSB Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8S9AC 1.83 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZSB Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 5TKDA 1.92 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 7GL Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 5TKDB 1.92 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 7GL Type1 581 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 3ZONA 2.15 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao IK1 Type1 577 - 870 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NZRA 2.56 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao LAJ Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NZRB 2.56 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao LAJ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 4WOVA 1.8 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 3SM Type1 580 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 4WOVB 1.8 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 3SM Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NSLA 2.15 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao KZJ Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NSLB 2.15 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao KZJ Type1 581 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NZEA 1.96 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao L8Y Type1 581 - 863 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NZEB 1.96 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao L8Y Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NZFA 2.39 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao L91 Type1 580 - 865 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NZFB 2.39 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao L91 Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NZHA 2.73 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao L9A Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NZHB 2.73 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao L9A Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NZPA 2.35 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao LB7 Type1 580 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NZPB 2.35 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao LB7 Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NZQA 2.11 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao LB4 Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 6NZQB 2.11 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao LB4 Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 7K7OA 2.82 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao VZJ Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 7K7OB 2.82 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao VZJ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 7K7QA 2.27 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao VZG Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 7K7QB 2.27 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao VZG Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8TB5A 2.32 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZOQ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8TB5B 2.32 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZOQ Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8TB6A 1.96 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZOI Type1 572 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8TB6B 1.96 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZOI Type1 580 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 5C01A 2.15 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao UNL Type1 580 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 5C01B 2.15 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao UNL Type1 579 - 869 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
OTHER NFR5-12 Q70KR1_LOTJA 8S79A 2.29 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 280 - 563 0 None None Nod-factor receptor 5 Lotus japonicus
OTHER NFR5-12 Q70KR1_LOTJA 8S79B 2.29 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 300 - 563 0 None None Nod-factor receptor 5 Lotus japonicus
TKL LYR4 G7K7K0_MEDTR 8PS7B 2.1 Pseudo DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_iioo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
TKL LYR4 G7K7K0_MEDTR 8PS7A 2.1 Pseudo DFGin‑None out-out out-out nonTYR APEdihe_aaoii APEdist_oooo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
OTHER MLKL MLKL_MOUSE 4M68A 1.696 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER MLKL MLKL_MOUSE 4BTFA 2.604 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 2 - 463 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER MLKL MLKL_MOUSE 4M69B 2.497 Pseudo None‑None out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER POMK SG196_MOUSE 5GZ9A 2.4 Pseudo DFGin‑ABAminus none-na in-out nonTYR APEdihe_aaiao APEdist_iioo ANP, MAN ATPlike, Allosteric 54 - 337 0 None N66Q,N164Q Protein O-mannose kinase Mus musculus
OTHER POMK SG196_MOUSE 5GZ8A 2.5 Pseudo DFGin‑ABAminus none-na in-out nonTYR APEdihe_aaiao APEdist_iooo No_ligand No_ligand 54 - 337 0 None N66Q,N164Q Protein O-mannose kinase Mus musculus
OTHER PAN3 PAN3_NEUCR 4BWKA 3.3 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 235 - 646 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWKB 3.3 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 235 - 646 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4CZYB 3.4 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 234 - 645 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4CZYD 3.4 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 234 - 645 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWXA 2.85 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 234 - 646 0 None L510M,G511P,G512M,T514G,T515A,H516R,L517F PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWXB 2.85 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 234 - 646 0 None L510M,G511P,G512M,T514G,T515A,H516R,L517F PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
CAMK None A0A3P9GXN4_ORYLA 9QJ2A 2.1 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 421 - 763 0 None None Uncharacterized protein Oryzias latipes
CAMK None A0A3P9GXN4_ORYLA 9QJ2B 2.1 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 419 - 763 0 None None Uncharacterized protein Oryzias latipes
CAMK CASK CSKP_RAT 6LNMA 2.4 Pseudo DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 335 0 None None Peripheral plasma membrane protein CASK Rattus norvegicus
CAMK CASK CSKP_RAT 6LNMC 2.4 Pseudo DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 335 0 None None Peripheral plasma membrane protein CASK Rattus norvegicus
CAMK CASK CSKP_RAT 6LNME 2.4 Pseudo DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 335 0 None None Peripheral plasma membrane protein CASK Rattus norvegicus
OTHER MLKL D3ZKP6_RAT 6VBZA 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 183 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
OTHER MLKL D3ZKP6_RAT 6VBZB 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 182 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
OTHER PRAG1 PRAG1_RAT 6EWXB 2.771 Pseudo DFGin‑BLAminus none-na in-out nonTYR APEdihe_aaooo APEdist_nnno No_ligand No_ligand 909 - 1368 0 None None Inactive tyrosine-protein kinase PRAG1 Rattus norvegicus
OTHER PRAG1 PRAG1_RAT 6EWXA 2.771 Pseudo None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 914 - 1368 0 None None Inactive tyrosine-protein kinase PRAG1 Rattus norvegicus
OTHER CEX1 CEX1_YEAST 3VWAA 2.2 Pseudo DFGin‑BLAminus in-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 9 - 544 0 None None Cytoplasmic export protein 1 Saccharomyces cerevisiae
OTHER CEX1 CEX1_YEAST 3VWAB 2.2 Pseudo DFGin‑BLAminus in-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 9 - 543 0 None None Cytoplasmic export protein 1 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7C 3.796 Pseudo DFGin‑ABAminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 227 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7B 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 226 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7E 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 252 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7F 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 228 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7H 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 250 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7I 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 229 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7K 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 232 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7L 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 228 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 6R5KN 4.8 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 226 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 6R5KO 4.8 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 224 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER DRIK1 C0P4K9_MAIZE 6CPYA 1.7 Pseudo DFGout‑BBAminus in-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 187 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER DRIK1 C0P4K9_MAIZE 6CPYB 1.7 Pseudo DFGout‑BBAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 209 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER DRIK1 C0P4K9_MAIZE 6EASA 2.0 Pseudo DFGout‑BBAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn J3A Type1 208 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER SIRK1 K7VIQ3_MAIZE 5UV4A 2.3 Pseudo DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaono APEdist_oioo ANP ATPlike 744 - 1045 0 None None Putative leucine-rich repeat protein kinase family protein Zea mays

Activity: Pseudo (pseudokinase)

Total number of chains: 76
Active chains: 0
Total number of genes: 18
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 31 40.8% 5GZAA
DFGin BLAminus 10 13.2% 8AK2A
None None 10 13.2% 4M69B
DFGin BLBminus 9 11.8% 6VC0A
DFGin ABAminus 5 6.6% 9QJ2A
DFGout None 5 6.6% 4I93A
DFGout BBAminus 3 3.9% 6CPYA
DFGin BLAplus 2 2.6% 4BTFA
DFGin BLBplus 1 1.3% 5UV4A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER BIR2 BIR2_ARATH 4L68A 2.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiai APEdist_nioi PDO Allosteric 272 - 600 0 None None Inactive LRR receptor-like serine/threonine-protein kinase BIR2 Arabidopsis thaliana
OTHER BIR2 BIR2_ARATH 4L68B 2.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoao APEdist_oooo No_ligand No_ligand 271 - 600 0 None None Inactive LRR receptor-like serine/threonine-protein kinase BIR2 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I94A 1.8 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo ANP ATPlike 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I94B 1.8 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo ANP ATPlike 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I92A 1.6 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iooo No_ligand No_ligand 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I93A 1.5 Pseudo DFGout‑None out-out out-out nonTYR APEdihe_aaiai APEdist_iioo No_ligand No_ligand 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER BSK8 BSK8_ARATH 4I93B 1.5 Pseudo DFGout‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 40 - 328 0 None None Serine/threonine-protein kinase BSK8 Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAA 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAB 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAC 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL2 Q9FGG5_ARATH 6LBAD 4.1 Pseudo None‑None none-none out-none nonTYR APEdihe_aanai APEdist_nnnn No_ligand No_ligand 1 - 570 0 None None Protein kinase family protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4A 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4B 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4C 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER MLKL3 Q9LMN2_ARATH 6KA4D 3.4 Pseudo None‑None none-na out-out nonTYR APEdihe_aanao APEdist_nnnn No_ligand No_ligand 325 - 900 0 None None F22L4.1 protein Arabidopsis thaliana
OTHER STKLD1 F1MSZ0_BOVIN 9FQRXR 5.0 Pseudo DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaoai APEdist_oooo No_ligand No_ligand 1 - 610 0 None None Serine/threonine kinase like domain containing 1 Bos taurus
OTHER PAN3 PAN3_CHATD 4CYIA 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIB 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 213 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIC 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYID 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 214 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIE 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIF 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 213 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIG 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 212 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYIH 2.42 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 215 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJA 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 630 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJB 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJC 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 210 - 632 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER PAN3 PAN3_CHATD 4CYJD 2.59 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ATP ATPlike 207 - 631 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Chaetomium thermophilum
OTHER POMK SG196_DANRE 5GZAA 2.0 Pseudo DFGin‑None none-na in-out nonTYR APEdihe_aaioo APEdist_iioo ADP, ZZ1 ATPlike, Allosteric 53 - 342 0 None None Protein O-mannose kinase Danio rerio
CAMK OBSCN-1 OBSCN_DROME 8AK3A 1.9 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii ADP ATPlike 3186 - 3477 0 None None Protein Obscurin Drosophila melanogaster
CAMK OBSCN-1 OBSCN_DROME 8AK2A 1.75 Pseudo DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiai APEdist_iiii No_ligand No_ligand 3186 - 3472 0 None None Protein Obscurin Drosophila melanogaster
OTHER PAN3 PAN3_DROME 4BWPA 3.6 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AN2 ATPlike 379 - 787 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Drosophila melanogaster
OTHER PAN3 PAN3_DROME 4BWPB 3.6 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AN2 ATPlike 379 - 787 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Drosophila melanogaster
OTHER MLKL F6S337_HORSE 6VC0A 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 536 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER MLKL F6S337_HORSE 6VC0B 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 258 - 537 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER MLKL F6S337_HORSE 6VC0C 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 541 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
OTHER NFR5-12 Q70KR1_LOTJA 8S79A 2.29 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 280 - 563 0 None None Nod-factor receptor 5 Lotus japonicus
OTHER NFR5-12 Q70KR1_LOTJA 8S79B 2.29 Pseudo DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 300 - 563 0 None None Nod-factor receptor 5 Lotus japonicus
TKL LYR4 G7K7K0_MEDTR 8PS7B 2.1 Pseudo DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaooi APEdist_iioo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
TKL LYR4 G7K7K0_MEDTR 8PS7A 2.1 Pseudo DFGin‑None out-out out-out nonTYR APEdihe_aaoii APEdist_oooo ANP ATPlike 340 - 636 0 None None LysM-domain receptor-like kinase Medicago truncatula
OTHER MLKL MLKL_MOUSE 4M68A 1.696 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER MLKL MLKL_MOUSE 4BTFA 2.604 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 2 - 463 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER MLKL MLKL_MOUSE 4M69B 2.497 Pseudo None‑None out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
OTHER POMK SG196_MOUSE 5GZ9A 2.4 Pseudo DFGin‑ABAminus none-na in-out nonTYR APEdihe_aaiao APEdist_iioo ANP, MAN ATPlike, Allosteric 54 - 337 0 None N66Q,N164Q Protein O-mannose kinase Mus musculus
OTHER POMK SG196_MOUSE 5GZ8A 2.5 Pseudo DFGin‑ABAminus none-na in-out nonTYR APEdihe_aaiao APEdist_iooo No_ligand No_ligand 54 - 337 0 None N66Q,N164Q Protein O-mannose kinase Mus musculus
OTHER PAN3 PAN3_NEUCR 4BWKA 3.3 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 235 - 646 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWKB 3.3 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 235 - 646 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4CZYB 3.4 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 234 - 645 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4CZYD 3.4 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa ANP ATPlike 234 - 645 0 None None PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWXA 2.85 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 234 - 646 0 None L510M,G511P,G512M,T514G,T515A,H516R,L517F PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
OTHER PAN3 PAN3_NEUCR 4BWXB 2.85 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa AGS ATPlike 234 - 646 0 None L510M,G511P,G512M,T514G,T515A,H516R,L517F PAN2-PAN3 deadenylation complex subunit pan3 Neurospora crassa
CAMK None A0A3P9GXN4_ORYLA 9QJ2A 2.1 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 421 - 763 0 None None Uncharacterized protein Oryzias latipes
CAMK None A0A3P9GXN4_ORYLA 9QJ2B 2.1 Pseudo DFGin‑ABAminus out-out in-out nonTYR APEdihe_aaiii APEdist_iooo No_ligand No_ligand 419 - 763 0 None None Uncharacterized protein Oryzias latipes
CAMK CASK CSKP_RAT 6LNMA 2.4 Pseudo DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 335 0 None None Peripheral plasma membrane protein CASK Rattus norvegicus
CAMK CASK CSKP_RAT 6LNMC 2.4 Pseudo DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 335 0 None None Peripheral plasma membrane protein CASK Rattus norvegicus
CAMK CASK CSKP_RAT 6LNME 2.4 Pseudo DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 335 0 None None Peripheral plasma membrane protein CASK Rattus norvegicus
OTHER MLKL D3ZKP6_RAT 6VBZA 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 183 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
OTHER MLKL D3ZKP6_RAT 6VBZB 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 182 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
OTHER PRAG1 PRAG1_RAT 6EWXB 2.771 Pseudo DFGin‑BLAminus none-na in-out nonTYR APEdihe_aaooo APEdist_nnno No_ligand No_ligand 909 - 1368 0 None None Inactive tyrosine-protein kinase PRAG1 Rattus norvegicus
OTHER PRAG1 PRAG1_RAT 6EWXA 2.771 Pseudo None‑None none-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 914 - 1368 0 None None Inactive tyrosine-protein kinase PRAG1 Rattus norvegicus
OTHER CEX1 CEX1_YEAST 3VWAA 2.2 Pseudo DFGin‑BLAminus in-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 9 - 544 0 None None Cytoplasmic export protein 1 Saccharomyces cerevisiae
OTHER CEX1 CEX1_YEAST 3VWAB 2.2 Pseudo DFGin‑BLAminus in-na in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 9 - 543 0 None None Cytoplasmic export protein 1 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7C 3.796 Pseudo DFGin‑ABAminus out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 227 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7B 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 226 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7E 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 252 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7F 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 228 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7H 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 250 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7I 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 229 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7K 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 232 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 4XR7L 3.796 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 228 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 6R5KN 4.8 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 226 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER PAN3-12 PAN3_YEAST 6R5KO 4.8 Pseudo DFGin‑None out-na out-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 224 - 679 0 None None PAN2-PAN3 deadenylation complex subunit PAN3 Saccharomyces cerevisiae
OTHER DRIK1 C0P4K9_MAIZE 6CPYA 1.7 Pseudo DFGout‑BBAminus in-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 187 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER DRIK1 C0P4K9_MAIZE 6CPYB 1.7 Pseudo DFGout‑BBAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 209 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER DRIK1 C0P4K9_MAIZE 6EASA 2.0 Pseudo DFGout‑BBAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn J3A Type1 208 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER SIRK1 K7VIQ3_MAIZE 5UV4A 2.3 Pseudo DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaono APEdist_oioo ANP ATPlike 744 - 1045 0 None None Putative leucine-rich repeat protein kinase family protein Zea mays