Ligand: 7GL

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 5TKDA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR TYK2-1 TYK2_HUMAN 5TKDA 1.92 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 7GL Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 5TKDB 1.92 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 7GL Type1 581 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2

Ligand: 7GL

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 5TKDA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR TYK2-1 TYK2_HUMAN 5TKDA 1.92 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 7GL Type1 581 - 866 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 5TKDB 1.92 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao 7GL Type1 581 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens

Ligand: 7GL

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism