Ligand: B8Z

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 7XC1A
DFGin None 1 50.0% 8X3MA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK1 MK01_HUMAN 7XC1A 2.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 5ID, B8Z Type1, Allosteric 10 - 360 0 None None Mitogen-activated protein kinase 1
CMGC MAPK14 MK14_HUMAN 8X3MA 1.85 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaooi APEdist_oooo B8Z Allosteric 4 - 353 0 None None Mitogen-activated protein kinase 14

Ligand: B8Z

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 7XC1A
DFGin None 1 50.0% 8X3MA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK1 MK01_HUMAN 7XC1A 2.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_ioii 5ID, B8Z Type1, Allosteric 10 - 360 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK14 MK14_HUMAN 8X3MA 1.85 Inactive DFGin‑None in-in out-out nonTYR APEdihe_aaooi APEdist_oooo B8Z Allosteric 4 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens

Ligand: B8Z

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism