CMGC_MAPK1 (Mitogen-activated protein kinase 1)

Total number of chains: 175
Active chains: 12
Uniprot: MK01_HUMAN
Kinase Domain Residues: 25 - 313
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 172 98.3% AF-P28482-K1A
DFGin ABAminus 3 1.7% 1WZYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAPK1 6OPGA P28482 10 358 360.0 ANP:60401 ATPlike Active DFGin 6.5353 14.6675 BLAminus -130.49, -173.97 55.35, 72.85 -87.66, 25.26 285.94, 65.79 -65.31, -19.22 in-in in 9.0658 Saltbr-in 2.6952 HRD-in -72.87, -54.34 77.9, 3.87 in-in-in SNCiii in-in ActLoopNT-in 2.7583 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -102.35, 163.88 APE9-dihe-na 79.13, 168.47 APE8-dihe-in -88.92, 138.85 APE8-rot-in 292.11 APE67-dihe-in -68.23, -14.82 -51.35, -45.86 APE12-dist-in 12.5703 APE11-dist-in 11.1338 APE10-dist-in 6.6534 APE9-dist-in 2.9424 None TPO185,PTR187 TPO185,PTR187 XRAY 2.9 0.16 0.239 A 354.0 349.0 0 31 31 0 [[25, 313]] 1.0 6opg CMGC_MAPK1_HUMAN CMGC 8.6e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5V60A P28482 10 358 360.0 ACP:401 ATPlike Active DFGin 6.6686 14.8874 BLAminus -124.21, -175.27 60.56, 75.29 -91.11, 25.45 286.11, 68.09 -67.4, -23.76 in-in in 9.2691 Saltbr-in 3.0882 HRD-in -75.88, -52.24 69.24, 12.32 in-in-in SNCiii in-in ActLoopNT-in 2.9513 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -89.66, 171.23 APE9-dihe-na 66.7, 168.41 APE8-dihe-in -89.68, 141.19 APE8-rot-in 301.48 APE67-dihe-in -66.12, -19.67 -43.41, -50.15 APE12-dist-in 12.5737 APE11-dist-in 11.0864 APE10-dist-in 6.6326 APE9-dist-in 2.9874 None TPO185,PTR187 TPO185,PTR187 XRAY 2.18 0.193 0.226 A 356.0 349.0 0 31 31 0 [[25, 313]] 1.0 5v60 CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 AF-P28482-K1A P28482 17 321 360.0 No_ligand No_ligand Active DFGin 6.7095 15.0324 BLAminus -132.81, 178.26 60.0, 67.32 -79.82, 13.55 287.23, 76.28 -59.44, -30.59 in-in in 9.2916 Saltbr-in 2.7372 HRD-in -72.76, -45.83 65.72, 5.09 in-in-in SNCiii in-in ActLoopNT-in 2.8716 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -80.26, 168.0 APE9-dihe-na 60.74, 145.84 APE8-dihe-in -61.61, 133.3 APE8-rot-in 298.45 APE67-dihe-in -68.84, -20.54 -48.48, -45.65 APE12-dist-in 12.8219 APE11-dist-in 11.2042 APE10-dist-in 6.9498 APE9-dist-in 3.0736 None None None AF2 -1.0 1.0 1.0 A 305.0 305.0 0 31 31 0 [[25, 313]] 1.0 AF-P28482-K1 CMGC_MAPK1_HUMAN CMGC 5e-86 294.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 AF-P28482-K3A P28482 17 321 360.0 No_ligand No_ligand Active DFGin 6.7222 14.81 BLAminus -134.49, 179.63 60.4, 61.52 -74.0, 13.5 286.26, 78.19 -60.59, -24.27 in-in in 9.4022 Saltbr-in 2.8005 HRD-in -75.01, -46.98 64.78, 12.11 in-in-in SNCiii in-in ActLoopNT-in 2.8388 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -117.94, 171.15 APE9-dihe-na 58.96, 136.08 APE8-dihe-in -57.85, 133.77 APE8-rot-in 294.09 APE67-dihe-in -67.48, -19.97 -48.51, -44.4 APE12-dist-in 13.0255 APE11-dist-in 10.751 APE10-dist-in 6.4788 APE9-dist-in 3.0995 None None None AF2 -1.0 1.0 1.0 A 305.0 305.0 0 31 31 0 [[25, 313]] 1.0 AF-P28482-K3 CMGC_MAPK1_HUMAN CMGC 5e-86 294.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5V61A P28482 10 359 360.0 No_ligand No_ligand Active DFGin 6.6537 15.6953 BLAminus -127.45, -177.89 71.76, 74.38 -98.23, 26.0 278.7, 71.15 -67.96, -26.05 in-in in 9.6567 Saltbr-in 2.6849 HRD-in -74.15, -53.14 74.14, 10.93 in-in-in SNCiii in-in ActLoopNT-in 2.8197 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -93.7, 172.55 APE9-dihe-na 68.11, 165.25 APE8-dihe-in -89.72, 145.0 APE8-rot-in 300.7 APE67-dihe-in -67.44, -18.57 -46.35, -49.99 APE12-dist-in 12.4561 APE11-dist-in 11.172 APE10-dist-in 6.5301 APE9-dist-in 2.9821 None TPO185,PTR187 TPO185,PTR187 XRAY 2.2 0.178 0.212 A 356.0 350.0 0 31 31 0 [[25, 313]] 1.0 5v61 CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6OPHA P28482 11 358 360.0 6QB:60401 Type1 Active DFGin 6.7981 15.0588 BLAminus -130.04, 176.89 62.64, 86.8 -99.79, 23.69 285.42, 69.18 -59.71, -37.46 in-in in 9.1055 Saltbr-in 2.7 HRD-in -73.41, -55.53 80.22, 3.3 in-in-in SNCiii in-in ActLoopNT-in 2.9027 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -99.5, 167.6 APE9-dihe-na 71.49, 153.42 APE8-dihe-in -69.32, 138.47 APE8-rot-in 307.19 APE67-dihe-in -58.06, -18.68 -49.97, -53.1 APE12-dist-in 12.741 APE11-dist-in 11.1224 APE10-dist-in 6.801 APE9-dist-in 3.0809 None TPO185,PTR187 TPO185,PTR187 XRAY 2.4 0.195 0.243 A 354.0 348.0 0 31 31 0 [[25, 313]] 1.0 6oph CMGC_MAPK1_HUMAN CMGC 8.6e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8U8JA P28482 7 358 360.0 WAL:60401 Type1 Active DFGin 6.6924 14.6032 BLAminus -129.0, -177.16 58.24, 84.12 -98.97, 25.3 283.6, 66.7 -63.94, -32.37 in-in in 8.7414 Saltbr-in 2.8063 HRD-in -74.57, -53.96 73.73, 13.51 in-in-in SNCiii in-in ActLoopNT-in 2.8191 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.04, 171.8 APE9-dihe-na 68.12, 168.69 APE8-dihe-in -92.27, 141.81 APE8-rot-in 299.3 APE67-dihe-in -59.84, -16.28 -46.87, -56.27 APE12-dist-in 12.6139 APE11-dist-in 11.0733 APE10-dist-in 6.573 APE9-dist-in 2.9829 A7S TPO185,PTR187 TPO185,PTR187 XRAY 2.1 0.18 0.227 A 354.0 352.0 0 31 31 0 [[25, 313]] 1.0 8u8j CMGC_MAPK1_HUMAN CMGC 8.6e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8U8KA P28482 10 358 360.0 W8U:60401 Type1 Active DFGin 6.7234 14.4664 BLAminus -129.74, -176.79 54.57, 88.21 -99.75, 25.02 286.15, 64.72 -60.73, -30.08 in-in in 8.6454 Saltbr-in 2.7029 HRD-in -73.18, -50.61 71.52, 11.37 in-in-in SNCiii in-in ActLoopNT-in 2.8181 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -94.55, 172.59 APE9-dihe-na 66.8, 166.42 APE8-dihe-in -88.85, 143.17 APE8-rot-in 296.07 APE67-dihe-in -63.45, -15.66 -52.73, -51.37 APE12-dist-in 12.6541 APE11-dist-in 11.1956 APE10-dist-in 6.7124 APE9-dist-in 2.9607 A7S TPO185,PTR187 TPO185,PTR187 XRAY 2.1 0.176 0.213 A 354.0 349.0 0 31 31 0 [[25, 313]] 1.0 8u8k CMGC_MAPK1_HUMAN CMGC 8.6e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QTEA P28482 11 358 360.0 390:430 Type1 Active DFGin 6.9092 15.0118 BLAminus -128.11, 177.87 65.48, 81.01 -97.8, 24.52 281.71, 68.7 -63.45, -27.47 in-in in 9.4461 Saltbr-in 2.8495 HRD-in -77.98, -52.32 76.82, 3.18 in-in-in SNCiii in-in ActLoopNT-in 2.7899 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -92.78, -31.85 APE9-dihe-na -67.91, 159.3 APE8-dihe-in -56.84, 129.56 APE8-rot-in 308.17 APE67-dihe-in -65.89, -13.13 -51.33, -50.7 APE12-dist-in 13.9805 APE11-dist-in 11.0006 APE10-dist-in 7.1835 APE9-dist-in 4.3781 None None None XRAY 1.5 0.147 0.167 A 361.0 348.0 0 31 31 0 [[25, 313]] 1.0 4qte CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G54A P28482 10 356 360.0 6H3:403 Type1 Active DFGin 6.8714 16.2079 BLAminus -132.88, -179.11 65.87, 69.62 -92.42, 26.13 283.45, 69.74 -65.96, -27.02 out-in out 10.1983 Saltbr-in 2.7797 HRD-in -75.15, -46.62 69.02, 1.28 in-in-in SNCiii in-in ActLoopNT-in 2.7772 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.74, -31.04 APE9-dihe-na -74.65, 165.75 APE8-dihe-in -65.58, 131.17 APE8-rot-in 305.71 APE67-dihe-in -65.73, -17.41 -55.69, -47.01 APE12-dist-in 13.6771 APE11-dist-in 10.778 APE10-dist-in 6.6196 APE9-dist-in 4.3477 None None None XRAY 2.05 0.185 0.221 A 361.0 347.0 0 31 31 0 [[25, 313]] 1.0 6g54 CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7OPMA P28482 1 360 360.0 08G:60401 Type1 Active DFGin 7.0654 15.2747 BLAminus -129.98, -173.24 56.69, 70.0 -91.64, 20.03 282.06, 60.94 -67.35, -36.15 in-in in 9.3584 Saltbr-in 2.8706 HRD-in -71.5, -50.41 70.44, 8.29 in-in-in SNCiii in-in ActLoopNT-in 3.0369 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.91, 154.41 APE9-dihe-na 75.03, 163.11 APE8-dihe-in -83.61, 145.58 APE8-rot-in 304.37 APE67-dihe-in -70.53, -18.9 -53.65, -46.6 APE12-dist-in 12.857 APE11-dist-in 10.6299 APE10-dist-in 6.8222 APE9-dist-in 2.9125 None TPO185,PTR187 TPO185,PTR187 XRAY 2.45 0.237 0.254 A 364.0 360.0 0 31 31 0 [[25, 313]] 1.0 7opm CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5V62A P28482 10 360 360.0 FRZ:406,AKS:407 Type1,Type1 Active DFGin 6.7632 15.4903 BLAminus -124.1, -176.99 62.38, 83.65 -99.36, 23.82 282.86, 70.28 -72.33, -19.01 in-in in 9.4684 Saltbr-in 2.7517 HRD-in -71.83, -53.45 74.5, 7.81 in-in-in SNCiii in-in ActLoopNT-in 2.8475 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -92.82, 173.28 APE9-dihe-na 63.65, 166.64 APE8-dihe-in -87.4, 138.22 APE8-rot-in 297.67 APE67-dihe-in -61.77, -20.72 -44.24, -52.92 APE12-dist-in 12.7519 APE11-dist-in 11.496 APE10-dist-in 6.8896 APE9-dist-in 3.011 None TPO185,PTR187 TPO185,PTR187 XRAY 1.9 0.172 0.203 A 351.0 351.0 0 31 31 0 [[25, 313]] 1.0 5v62 CMGC_MAPK1_HUMAN CMGC 8.4e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8PVUE P28482 24 356 360.0 No_ligand No_ligand Inactive DFGin 7.5932 17.6539 ABAminus -114.83, -57.91 -91.0, 132.04 -139.19, 12.86 275.21, 83.7 -61.84, -46.11 out-out out 10.7362 Saltbr-out 8.7045 HRD-out -102.83, 165.82 -156.25, 160.83 out-in-out SNCoio in-out ActLoopNT-in 2.7273 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -111.07, 147.6 APE9-dihe-na -61.46, -46.75 APE8-dihe-in -129.35, 137.9 APE8-rot-out 88.46 APE67-dihe-in -64.45, -31.6 -96.79, 2.11 APE12-dist-in 7.989 APE11-dist-in 11.069 APE10-dist-out 8.9712 APE9-dist-out 10.4542 None None None EM 3.5 999.0 999.0 E 361.0 301.0 26 31 21 10 [[25, 313]] 1.0 8pvu CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 1WZYA P28482 8 357 360.0 F29:1001 Type1 Inactive DFGin 6.6131 16.4587 ABAminus -125.93, -57.84 -77.7, 107.83 -107.25, 23.47 285.61, 70.28 -59.34, -21.19 in-in in 9.1317 Saltbr-in 3.0816 HRD-in -62.8, -52.83 70.84, 12.27 in-in-out SNCiio in-out ActLoopNT-in 2.7562 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oioo APE10-dihe-na -46.86, 125.25 APE9-dihe-na -155.12, -47.66 APE8-dihe-out 71.65, 79.94 APE8-rot-in 312.9 APE67-dihe-out -142.94, -5.88 -171.91, -165.7 APE12-dist-out 15.2135 APE11-dist-in 10.1751 APE10-dist-out 10.4542 APE9-dist-out 7.3014 None None None XRAY 2.5 0.253 0.292 A 368.0 350.0 0 31 31 0 [[25, 313]] 1.0 1wzy CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 1TVOA P28482 8 357 360.0 FRZ:1001 Type1 Inactive DFGin 6.7353 16.5441 ABAminus -143.04, -21.92 -99.58, 92.28 -97.21, 29.04 291.9, 66.95 -57.83, -37.85 in-in in 9.483 Saltbr-in 2.9404 HRD-in -68.59, -45.64 64.32, 6.29 in-in-out SNCiio in-out ActLoopNT-in 2.8901 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.95, -31.57 APE9-dihe-na -57.23, 155.98 APE8-dihe-in -48.99, 121.33 APE8-rot-in 300.25 APE67-dihe-in -55.04, -19.18 -44.3, -60.26 APE12-dist-out 14.2385 APE11-dist-in 11.1478 APE10-dist-in 7.5063 APE9-dist-in 4.4953 None None None XRAY 2.5 0.266 0.272 A 368.0 350.0 0 31 31 0 [[25, 313]] 1.0 1tvo CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4H3QA P28482 9 360 360.0 ANP:401 ATPlike Inactive DFGin 6.6034 15.6819 BLAminus -131.43, 178.9 70.32, 68.42 -96.0, 22.91 290.2, 68.59 -63.35, -20.75 in-in in 9.2328 Saltbr-in 2.8208 HRD-in -71.26, -48.66 68.7, 4.98 in-in-out SNCiio in-out ActLoopNT-in 2.9419 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_iioo APE10-dihe-na -133.14, 155.68 APE9-dihe-na -60.56, -35.88 APE8-dihe-out -124.57, -73.58 APE8-rot-out 150.68 APE67-dihe-out -67.06, -6.51 92.51, -9.23 APE12-dist-in 9.1353 APE11-dist-in 11.6615 APE10-dist-out 8.7525 APE9-dist-out 10.9003 R77A,C161S,I255G,E314A None None XRAY 2.2 0.184 0.232 A 362.0 352.0 0 31 31 0 [[25, 313]] 1.0 4h3q CMGC_MAPK1_HUMAN CMGC 3.4e-85 291.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4IZ5A P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.5744 16.2257 BLAminus -133.03, 170.47 61.68, 96.87 -113.24, 29.97 280.98, 72.88 -75.05, -15.97 in-out in 8.9431 Saltbr-out 6.3365 HRD-in -70.37, -54.19 76.22, -6.05 out-in-out SNCoio in-out ActLoopNT-in 2.8045 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -135.59, 107.64 APE9-dihe-na -86.59, -36.52 APE8-dihe-in -63.86, 130.93 APE8-rot-in 305.07 APE67-dihe-in -64.33, -26.99 -124.19, 30.24 APE12-dist-in 10.0117 APE11-dist-out 7.082 APE10-dist-out 8.2491 APE9-dist-out 10.5104 T185E None None XRAY 3.19 0.245 0.292 A 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4IZ5B P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.6142 16.236 BLAminus -130.77, 169.05 63.18, 96.88 -112.33, 27.86 280.9, 72.0 -73.48, -17.21 in-out in 8.9516 Saltbr-out 6.2842 HRD-in -71.55, -52.24 74.21, -4.59 out-in-out SNCoio in-out ActLoopNT-in 2.846 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -135.05, 108.67 APE9-dihe-na -88.18, -35.19 APE8-dihe-in -65.83, 129.75 APE8-rot-in 303.93 APE67-dihe-in -64.9, -24.28 -122.7, 29.42 APE12-dist-in 10.0315 APE11-dist-out 7.0852 APE10-dist-out 8.2498 APE9-dist-out 10.5027 T185E None None XRAY 3.19 0.245 0.292 B 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4IZ5C P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.6044 16.2316 BLAminus -131.01, 170.44 62.04, 96.83 -112.78, 28.94 280.74, 73.4 -74.17, -17.63 in-out in 8.9448 Saltbr-out 6.3598 HRD-in -72.88, -51.67 75.48, -6.0 out-in-out SNCoio in-out ActLoopNT-in 2.8678 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -133.99, 108.02 APE9-dihe-na -87.46, -36.5 APE8-dihe-in -65.77, 130.32 APE8-rot-in 303.26 APE67-dihe-in -66.37, -24.82 -122.99, 29.53 APE12-dist-in 10.0145 APE11-dist-out 7.0682 APE10-dist-out 8.2202 APE9-dist-out 10.4967 T185E None None XRAY 3.19 0.245 0.292 C 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4IZ5D P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.6009 16.2317 BLAminus -131.94, 170.02 62.64, 97.08 -112.75, 27.73 280.79, 72.08 -72.23, -17.73 in-out in 8.9604 Saltbr-out 6.3214 HRD-in -71.89, -53.7 75.24, -4.58 out-in-out SNCoio in-out ActLoopNT-in 2.8465 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -135.09, 108.16 APE9-dihe-na -88.37, -35.4 APE8-dihe-in -66.59, 130.93 APE8-rot-in 303.88 APE67-dihe-in -65.41, -25.44 -123.75, 30.53 APE12-dist-in 10.0122 APE11-dist-out 7.0881 APE10-dist-out 8.224 APE9-dist-out 10.4605 T185E None None XRAY 3.19 0.245 0.292 D 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 2Y9QA P28482 9 358 360.0 ANP:1359 ATPlike Inactive DFGin 6.7756 15.4463 BLAminus -131.56, -173.58 71.27, 62.6 -94.15, 18.41 284.56, 67.7 -60.61, -22.82 in-in in 9.1065 Saltbr-in 2.7907 HRD-in -69.38, -48.16 75.91, -5.63 in-in-out SNCiio in-out ActLoopNT-in 2.7879 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -136.29, 162.19 APE9-dihe-na -69.67, -30.11 APE8-dihe-in -153.45, 140.36 APE8-rot-out 183.83 APE67-dihe-in -69.16, -12.41 -110.3, 4.7 APE12-dist-in 9.6632 APE11-dist-in 12.83 APE10-dist-out 9.194 APE9-dist-out 11.5088 None None None XRAY 1.55 0.156 0.177 A 362.0 350.0 0 31 31 0 [[25, 313]] 1.0 2y9q CMGC_MAPK1_HUMAN CMGC 9.3e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FMQA P28482 9 358 360.0 ANP:401 ATPlike Inactive DFGin 6.797 15.309 BLAminus -133.64, -170.94 67.61, 66.1 -98.24, 21.64 282.65, 68.61 -61.3, -22.42 in-in in 9.1314 Saltbr-in 2.9364 HRD-in -73.07, -47.52 74.25, -10.43 in-in-out SNCiio in-out ActLoopNT-in 2.8302 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -138.4, 159.9 APE9-dihe-na -70.94, -24.68 APE8-dihe-in -158.11, 141.22 APE8-rot-out 179.47 APE67-dihe-in -66.85, -11.48 -113.88, 6.26 APE12-dist-in 9.4738 APE11-dist-in 12.7001 APE10-dist-out 9.2253 APE9-dist-out 11.64 None None None XRAY 2.098 0.182 0.224 A 362.0 350.0 0 31 31 0 [[25, 313]] 1.0 4fmq CMGC_MAPK1_HUMAN CMGC 9.3e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4NIFB P28482 9 360 360.0 ANP:401 ATPlike Inactive DFGin 6.7638 15.4088 BLAminus -131.87, -169.42 69.51, 63.01 -98.39, 22.71 281.57, 68.87 -63.28, -26.61 in-in in 9.0075 Saltbr-in 2.7834 HRD-in -68.77, -49.09 76.18, -3.84 in-in-out SNCiio in-out ActLoopNT-in 2.7275 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -127.8, 161.08 APE9-dihe-na -75.51, -26.3 APE8-dihe-in -152.23, 138.84 APE8-rot-out 180.18 APE67-dihe-in -71.26, -8.82 -111.88, 5.33 APE12-dist-in 8.1996 APE11-dist-in 11.9615 APE10-dist-out 8.903 APE9-dist-out 11.5131 None None None XRAY 2.15 0.161 0.208 B 362.0 349.0 3 31 28 3 [[25, 313]] 1.0 4nif CMGC_MAPK1_HUMAN CMGC 9.3e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4NIFE P28482 10 360 360.0 ANP:401 ATPlike Inactive DFGin 6.7991 15.6006 BLAminus -132.52, -168.43 65.68, 64.41 -97.79, 21.09 277.61, 67.0 -63.55, -23.2 in-in in 9.1704 Saltbr-in 2.7133 HRD-in -70.38, -48.01 73.58, -2.52 in-in-out SNCiio in-out ActLoopNT-in 2.7288 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -128.04, 157.14 APE9-dihe-na -71.47, -27.38 APE8-dihe-in -153.58, 137.78 APE8-rot-out 179.37 APE67-dihe-in -68.22, -5.95 -110.7, 4.02 APE12-dist-in 8.1436 APE11-dist-in 11.9289 APE10-dist-out 8.9408 APE9-dist-out 11.5278 None None None XRAY 2.15 0.161 0.208 E 362.0 348.0 3 31 28 3 [[25, 313]] 1.0 4nif CMGC_MAPK1_HUMAN CMGC 9.3e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8PSRA P28482 1 358 360.0 ANP:401 ATPlike Inactive DFGin 6.7627 15.1158 BLAminus -130.96, -167.28 68.25, 62.57 -95.64, 20.11 282.69, 71.74 -68.98, -15.25 in-in in 8.941 Saltbr-in 2.8232 HRD-in -68.74, -46.55 75.16, -5.99 in-in-out SNCiio in-out ActLoopNT-in 2.7689 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -133.02, 153.53 APE9-dihe-na -66.89, -30.36 APE8-dihe-in -146.2, 134.03 APE8-rot-out 178.25 APE67-dihe-in -71.02, -10.13 -100.56, 5.83 APE12-dist-in 8.1678 APE11-dist-in 11.5467 APE10-dist-out 8.8891 APE9-dist-out 11.3605 None None None XRAY 1.85 0.183 0.209 A 364.0 354.0 4 31 27 4 [[25, 313]] 1.0 8psr CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 3TEIA P28482 10 358 360.0 ANP:401 ATPlike Inactive DFGin 6.743 15.9468 BLAminus -130.8, -176.53 59.31, 74.36 -93.64, 10.5 288.08, 72.41 -50.44, -31.09 in-in in 9.2714 Saltbr-in 3.1994 HRD-in -69.93, -52.25 74.6, -17.82 in-in-out SNCiio in-out ActLoopNT-in 2.7526 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na 66.02, 77.59 APE9-dihe-na -53.11, -45.5 APE8-dihe-in -109.04, 134.77 APE8-rot-out 40.2 APE67-dihe-in -60.63, -33.66 -94.81, 4.48 APE12-dist-in 8.7836 APE11-dist-in 10.9926 APE10-dist-out 8.5071 APE9-dist-out 11.1823 R77A,E314A None None XRAY 2.404 0.199 0.235 A 362.0 339.0 10 31 24 7 [[25, 313]] 1.0 3tei CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4H3PA P28482 11 359 360.0 ANP:401 ATPlike Inactive DFGin 6.7486 16.129 BLAminus -129.02, -179.26 65.06, 71.95 -98.46, 28.28 294.01, 75.31 -57.14, -23.59 in-in in 9.6015 Saltbr-in 3.0521 HRD-in -79.45, -54.12 78.74, 4.99 in-in-out SNCiio in-out ActLoopNT-in 2.7274 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -109.42, 169.7 APE9-dihe-na -56.98, -72.96 APE8-dihe-in -103.33, 144.18 APE8-rot-out 6.69 APE67-dihe-in -56.41, -28.74 -91.67, -5.29 APE12-dist-in 8.8946 APE11-dist-in 9.1851 APE10-dist-out 8.3832 APE9-dist-out 9.7322 R77A,E314A None None XRAY 2.3 0.18 0.224 A 362.0 342.0 7 31 24 7 [[25, 313]] 1.0 4h3p CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4H3PD P28482 11 359 360.0 ANP:401 ATPlike Inactive DFGin 6.7423 16.2695 BLAminus -128.42, -178.25 63.92, 70.53 -94.38, 28.0 287.67, 73.89 -60.9, -21.54 in-in in 9.383 Saltbr-in 3.4542 HRD-in -75.51, -54.76 82.18, -2.55 in-in-out SNCiio in-out ActLoopNT-in 2.6568 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 42.36 APE8-rot-out 66.34 APE67-dihe-in -61.9, -28.03 -63.57, -9.01 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 R77A,E314A None None XRAY 2.3 0.18 0.224 D 362.0 338.0 11 31 20 11 [[25, 313]] 1.0 4h3p CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8PSTA P28482 11 358 360.0 AN2:401,DC6:402 ATPlike,Allosteric Inactive DFGin 6.7851 16.1283 BLAminus -134.06, -179.16 64.02, 73.91 -96.68, 24.07 284.98, 72.99 -65.53, -24.17 in-out in 9.3377 Saltbr-out 3.8743 HRD-in -66.25, -48.73 76.74, -3.29 out-in-out SNCoio in-out ActLoopNT-in 2.739 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -76.72 APE8-dihe-in -121.88, 139.27 APE8-rot-out 177.73 APE67-dihe-in -63.49, -19.48 -93.88, -5.61 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.7648 None None None XRAY 1.9 0.192 0.224 A 364.0 333.0 15 31 18 13 [[25, 313]] 1.0 8pst CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8PSWA P28482 11 358 360.0 AN2:401,D2I:402 ATPlike,Allosteric Inactive DFGin 6.8713 16.2525 BLAminus -133.24, 178.92 60.17, 81.49 -98.82, 18.4 283.05, 77.14 -62.53, -21.73 in-out in 9.4184 Saltbr-out 4.1301 HRD-in -71.12, -49.26 76.63, -3.5 out-in-out SNCoio in-out ActLoopNT-in 2.7674 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nioo APE10-dihe-na -97.92, 161.43 APE9-dihe-na -86.07, -39.89 APE8-dihe-in -109.3, 110.17 APE8-rot-in 302.88 APE67-dihe-in -69.34, -10.4 -107.51, 8.93 APE12-dist-none 999.0 APE11-dist-in 10.1783 APE10-dist-out 8.2941 APE9-dist-out 11.0742 None None None XRAY 2.0 0.191 0.215 A 364.0 338.0 10 31 21 10 [[25, 313]] 1.0 8psw CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8PSYA P28482 11 358 360.0 AN2:401,EI0:402 ATPlike,Allosteric Inactive DFGin 6.977 16.2643 BLAminus -135.96, -178.59 63.47, 73.94 -97.05, 21.62 286.23, 79.85 -63.59, -23.12 in-out in 9.4371 Saltbr-out 4.3597 HRD-in -69.38, -42.87 69.92, -0.29 out-in-out SNCoio in-out ActLoopNT-in 2.8605 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -110.27, 143.52 APE9-dihe-na -55.43, -62.59 APE8-dihe-in -128.8, 133.66 APE8-rot-out 167.71 APE67-dihe-in -72.41, -12.11 -102.66, 18.87 APE12-dist-out 6.7454 APE11-dist-in 10.5215 APE10-dist-out 8.6185 APE9-dist-out 10.4447 None None None XRAY 2.55 0.192 0.232 A 364.0 340.0 8 31 23 8 [[25, 313]] 1.0 8psy CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8PT0A P28482 11 358 360.0 ANP:401,EAI:403 ATPlike,Allosteric Inactive DFGin 6.7034 15.5181 BLAminus -130.99, -173.26 73.92, 62.07 -95.1, 17.63 279.55, 70.77 -68.45, -13.49 in-in in 9.1413 Saltbr-in 2.8701 HRD-in -71.96, -48.9 77.41, -4.12 in-in-out SNCiio in-out ActLoopNT-in 2.6924 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -110.07, -36.78 APE9-dihe-na -83.86, 177.79 APE8-dihe-in -68.52, 145.31 APE8-rot-out 191.04 APE67-dihe-in -66.51, -15.78 -105.25, 7.42 APE12-dist-out 6.875 APE11-dist-in 12.4434 APE10-dist-out 12.5541 APE9-dist-out 9.9942 None None None XRAY 1.65 0.178 0.207 A 364.0 348.0 0 31 31 0 [[25, 313]] 1.0 8pt0 CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8PT1A P28482 11 359 360.0 ANP:401,E2A:402 ATPlike,Allosteric Inactive DFGin 6.7525 15.486 BLAminus -130.01, -175.04 73.39, 64.08 -95.46, 18.76 282.28, 68.91 -63.67, -19.55 in-in in 9.1894 Saltbr-in 2.8492 HRD-in -70.21, -47.68 76.07, -5.14 in-in-out SNCiio in-out ActLoopNT-in 2.6722 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -121.06, -17.86 APE9-dihe-na -106.9, -177.78 APE8-dihe-in -78.1, 145.34 APE8-rot-out 186.54 APE67-dihe-in -67.62, -15.27 -108.68, 6.96 APE12-dist-in 7.1713 APE11-dist-in 12.6151 APE10-dist-out 12.6307 APE9-dist-out 10.2747 None None None XRAY 1.8 0.18 0.206 A 364.0 349.0 0 31 31 0 [[25, 313]] 1.0 8pt1 CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8PT5A P28482 10 358 360.0 ANP:401,D5R:402 ATPlike,Allosteric Inactive DFGin 6.7902 15.3041 BLAminus -138.03, -165.34 60.19, 62.86 -94.09, 21.06 289.01, 63.44 -59.86, -23.15 in-in in 9.091 Saltbr-in 2.8817 HRD-in -75.18, -47.36 71.89, 2.28 in-in-out SNCiio in-out ActLoopNT-in 2.6856 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -138.15, 158.79 APE9-dihe-na -71.62, -19.38 APE8-dihe-in -154.23, 140.23 APE8-rot-out 183.5 APE67-dihe-in -63.22, -13.66 -125.12, 20.04 APE12-dist-in 7.6307 APE11-dist-in 11.4685 APE10-dist-out 8.7388 APE9-dist-out 11.2872 None None None XRAY 1.95 0.206 0.235 A 364.0 336.0 10 31 21 10 [[25, 313]] 1.0 8pt5 CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8R5FA P28482 11 359 360.0 ANP:401,Y3H:403 ATPlike,Allosteric Inactive DFGin 6.7147 15.4588 BLAminus -133.12, -173.02 67.59, 67.52 -98.89, 23.72 283.56, 67.1 -69.6, -17.36 in-in in 9.1414 Saltbr-in 2.9066 HRD-in -75.1, -48.03 76.68, -4.69 in-in-out SNCiio in-out ActLoopNT-in 2.6928 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -92.27 APE8-dihe-in -89.34, 137.7 APE8-rot-out 190.9 APE67-dihe-in -68.19, -17.69 -92.76, -0.83 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.6172 None None None XRAY 1.65 0.194 0.218 A 364.0 337.0 12 31 19 12 [[25, 313]] 1.0 8r5f CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7W5OB P28482 12 357 360.0 6GI:606 Allosteric Inactive DFGin 6.7291 15.966 BLAminus -130.99, -179.63 60.79, 79.04 -97.44, 21.46 284.57, 69.25 -51.76, -37.4 in-in in 9.205 Saltbr-in 2.9255 HRD-in -89.57, -49.89 81.11, -2.76 in-in-out SNCiio in-out ActLoopNT-in 2.6945 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -127.79, 113.11 APE9-dihe-na 67.74, 140.06 APE8-dihe-in -61.14, 150.09 APE8-rot-in 295.42 APE67-dihe-in -62.08, -24.55 -59.37, -51.13 APE12-dist-in 8.0847 APE11-dist-out 7.278 APE10-dist-in 7.6425 APE9-dist-in 2.9693 None None NEP125 XRAY 2.35 0.228 0.279 B 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 7w5o CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8PT3A P28482 10 359 360.0 D7O:401,ANP:405 Allosteric,ATPlike Inactive DFGin 6.7463 16.2954 BLAminus -133.05, 179.18 60.24, 82.09 -94.36, 25.54 283.73, 70.47 -58.59, -24.6 in-out in 9.2783 Saltbr-out 4.0942 HRD-in -70.52, -51.82 77.79, -2.53 out-in-out SNCoio in-out ActLoopNT-in 2.7512 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oiio APE10-dihe-na -134.69, 123.91 APE9-dihe-na -78.34, -33.65 APE8-dihe-in -152.41, 145.11 APE8-rot-out 185.39 APE67-dihe-in -63.56, -20.16 -105.73, 9.6 APE12-dist-out 6.368 APE11-dist-in 8.5922 APE10-dist-in 7.9732 APE9-dist-out 9.8583 None None None XRAY 1.8 0.189 0.222 A 364.0 344.0 6 31 25 6 [[25, 313]] 1.0 8pt3 CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6QAHA P28482 11 357 360.0 HVB:402,HVB:403 Allosteric,Allosteric Inactive DFGin 6.7581 16.1676 BLAminus -136.73, 179.29 62.82, 76.94 -93.86, 22.86 290.05, 77.22 -60.46, -27.45 in-out in 9.9877 Saltbr-out 4.0961 HRD-in -76.02, -51.2 74.22, -0.2 out-in-out SNCoio in-out ActLoopNT-in 2.7923 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -88.29, -39.06 APE9-dihe-na -75.24, 163.73 APE8-dihe-in -59.27, 129.3 APE8-rot-in 308.42 APE67-dihe-in -64.98, -18.58 -56.47, -46.56 APE12-dist-out 14.087 APE11-dist-in 10.975 APE10-dist-in 6.6547 APE9-dist-in 4.407 None None CME161 XRAY 1.58 0.182 0.212 A 368.0 340.0 1 31 31 0 [[25, 313]] 1.0 6qah CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6QALA P28482 11 357 360.0 HV2:405,HV2:406 Allosteric,Allosteric Inactive DFGin 6.7663 16.5446 BLAminus -128.18, 174.72 64.17, 81.73 -99.37, 22.14 287.42, 72.94 -62.7, -28.45 in-in in 9.8461 Saltbr-in 3.4028 HRD-in -71.58, -48.42 72.8, 2.63 in-in-out SNCiio in-out ActLoopNT-in 2.7899 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -53.19, 146.61 APE9-dihe-na 64.69, -178.57 APE8-dihe-in -92.49, 143.95 APE8-rot-in 292.68 APE67-dihe-in -64.62, -19.41 -47.49, -52.39 APE12-dist-in 13.4343 APE11-dist-in 11.3908 APE10-dist-out 8.7984 APE9-dist-in 3.1299 None None CME161 XRAY 1.57 0.18 0.223 A 368.0 336.0 3 31 31 0 [[25, 313]] 1.0 6qal CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6NBSA P28482 10 356 360.0 KJ7:60403,KJ4:60404 Allosteric,Allosteric Inactive DFGin 6.8606 16.4381 BLAminus -130.15, -176.79 62.06, 79.39 -99.12, 19.64 285.27, 77.93 -63.72, -24.16 out-out out 10.0889 Saltbr-out 4.0562 HRD-in -72.23, -53.85 78.37, 1.37 out-in-out SNCoio in-out ActLoopNT-in 2.7647 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -111.09, -39.9 APE9-dihe-na -62.98, 162.81 APE8-dihe-in -62.93, 129.71 APE8-rot-in 305.16 APE67-dihe-in -63.54, -20.73 -58.96, -45.64 APE12-dist-out 14.3826 APE11-dist-in 11.2122 APE10-dist-in 7.1517 APE9-dist-in 4.2928 None None None XRAY 1.9 0.182 0.222 A 367.0 342.0 0 31 31 0 [[25, 313]] 1.0 6nbs CMGC_MAPK1_HUMAN CMGC 1.4e-85 293.1 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AOGA P28482 11 356 360.0 N29:404,N29:405,N29:406 Allosteric,Allosteric,Type1 Inactive DFGin 6.797 16.4858 BLAminus -133.77, 177.3 62.93, 83.71 -95.49, 22.08 286.68, 76.51 -65.58, -25.0 in-in in 9.908 Saltbr-in 2.7554 HRD-in -73.03, -50.17 73.65, 0.94 in-in-out SNCiio in-out ActLoopNT-in 2.816 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -94.54, -38.19 APE9-dihe-na -68.42, 157.58 APE8-dihe-in -54.06, 126.74 APE8-rot-in 311.62 APE67-dihe-in -64.0, -16.82 -59.31, -46.71 APE12-dist-out 14.394 APE11-dist-in 11.0564 APE10-dist-in 6.9158 APE9-dist-in 4.287 None None CME161 XRAY 1.603 0.176 0.22 A 368.0 337.0 6 31 31 0 [[25, 313]] 1.0 8aog CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G8XA P28482 11 357 360.0 EQT:403,EQT:404 Allosteric,Type1 Inactive DFGin 6.9288 16.2202 BLAminus -127.0, 171.04 70.33, 87.86 -101.76, 19.42 286.15, 72.76 -67.01, -25.23 out-in out 10.0852 Saltbr-in 3.0522 HRD-in -69.17, -52.59 71.2, 7.28 in-in-out SNCiio in-out ActLoopNT-in 2.7992 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -94.81, 149.77 APE9-dihe-na 65.15, 178.01 APE8-dihe-in -91.48, 142.7 APE8-rot-in 291.51 APE67-dihe-in -61.14, -21.62 -49.32, -50.91 APE12-dist-in 13.4913 APE11-dist-in 11.4897 APE10-dist-out 8.911 APE9-dist-in 3.2276 None None CME161 XRAY 1.76 0.167 0.217 A 368.0 339.0 0 31 31 0 [[25, 313]] 1.0 6g8x CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6QA1A P28482 11 358 360.0 HVK:402,HVK:403,HVK:404,HVK:405,HVK:406,HVK:407,HVK:408 Allosteric,Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 6.7607 16.7277 BLAminus -135.55, 177.67 62.97, 80.07 -93.23, 24.97 286.56, 81.05 -59.92, -35.8 out-out out 10.1503 Saltbr-out 5.5045 HRD-in -69.93, -53.53 76.59, 4.02 out-in-out SNCoio in-out ActLoopNT-in 2.8001 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -107.89, -31.2 APE9-dihe-na -62.32, 155.7 APE8-dihe-in -48.95, 124.85 APE8-rot-in 312.15 APE67-dihe-in -64.53, -16.99 -56.95, -46.9 APE12-dist-out 14.383 APE11-dist-in 10.9687 APE10-dist-in 7.3149 APE9-dist-in 4.1957 None None CME161 XRAY 1.58 0.168 0.203 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 6qa1 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6QA4A P28482 11 357 360.0 HRZ:402,HRZ:403,HRZ:404,HRZ:405 Allosteric,Type1,Allosteric,Type3 Inactive DFGin 6.8578 16.3027 BLAminus -132.02, 179.08 62.09, 80.41 -97.94, 19.4 285.68, 75.69 -60.47, -28.93 out-out out 10.2657 Saltbr-out 7.1395 HRD-in -74.15, -50.25 74.19, 4.76 out-in-out SNCoio in-out ActLoopNT-in 2.7537 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -59.52, 147.4 APE9-dihe-na 65.62, 177.04 APE8-dihe-in -90.04, 144.19 APE8-rot-in 287.38 APE67-dihe-in -65.83, -19.24 -48.33, -51.06 APE12-dist-in 13.2476 APE11-dist-in 11.3163 APE10-dist-out 8.6837 APE9-dist-in 3.033 None None CME161 XRAY 1.6 0.176 0.215 A 368.0 337.0 2 31 31 0 [[25, 313]] 1.0 6qa4 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4IZ7A P28482 11 360 360.0 No_ligand No_ligand Inactive DFGin 6.7791 16.3853 BLAminus -132.97, -178.72 63.66, 80.29 -101.39, 20.27 283.23, 71.58 -61.04, -25.26 out-in out 10.3002 Saltbr-in 2.6775 HRD-in -78.11, -51.56 79.12, -6.4 in-in-out SNCiio in-out ActLoopNT-in 2.7898 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iiio APE10-dihe-na -85.94, 135.52 APE9-dihe-na -28.41, -102.11 APE8-dihe-in -66.17, 105.49 APE8-rot-in 328.49 APE67-dihe-in -65.55, -19.28 -51.85, -44.19 APE12-dist-in 12.3652 APE11-dist-in 11.8165 APE10-dist-in 5.9776 APE9-dist-out 6.7345 None None None XRAY 1.8 0.187 0.222 A 356.0 344.0 6 31 25 6 [[25, 313]] 1.0 4iz7 CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4IZ7C P28482 11 359 360.0 No_ligand No_ligand Inactive DFGin 6.8265 16.3954 BLAminus -132.72, -179.02 62.3, 79.44 -102.34, 20.3 285.22, 75.68 -54.93, -29.16 in-in in 9.9694 Saltbr-in 2.6399 HRD-in -74.05, -47.12 72.94, -4.3 in-in-out SNCiio in-out ActLoopNT-in 2.8605 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioo APE10-dihe-na -129.15, 147.4 APE9-dihe-na -70.28, -33.83 APE8-dihe-in -115.27, 111.37 APE8-rot-in 304.75 APE67-dihe-in -74.12, -3.61 -106.1, -7.47 APE12-dist-out 6.7811 APE11-dist-in 10.8335 APE10-dist-out 8.9253 APE9-dist-out 11.3512 None None None XRAY 1.8 0.187 0.222 C 356.0 340.0 9 31 22 9 [[25, 313]] 1.0 4iz7 CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4IZAA P28482 11 358 360.0 No_ligand No_ligand Inactive DFGin 6.7716 16.4482 BLAminus -129.85, -176.34 68.35, 73.87 -101.91, 18.02 280.1, 70.06 -62.61, -26.2 in-in in 9.9823 Saltbr-in 2.5085 HRD-in -67.1, -53.14 77.26, -1.94 in-in-out SNCiio in-out ActLoopNT-in 2.8209 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iooo APE10-dihe-na -129.09, 28.01 APE9-dihe-na -88.83, 7.82 APE8-dihe-out -120.34, 16.45 APE8-rot-in 313.77 APE67-dihe-in -71.68, -14.26 -48.45, -41.92 APE12-dist-in 11.2457 APE11-dist-out 7.4141 APE10-dist-out 12.8508 APE9-dist-out 9.9508 None TPO185,PTR187 TPO185,PTR187 XRAY 1.93 0.199 0.243 A 356.0 348.0 0 31 31 0 [[25, 313]] 1.0 4iza CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4IZAC P28482 11 358 360.0 No_ligand No_ligand Inactive DFGin 6.8504 16.4972 BLAminus -135.43, -175.74 69.86, 75.04 -101.18, 17.42 285.53, 76.16 -59.4, -25.37 out-none out 10.3448 Saltbr-none 999.0 HRD-in -67.56, -54.71 80.03, -9.06 none-in-out SNCnio in-out ActLoopNT-in 2.6429 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 126.48 APE8-rot-out 60.76 APE67-dihe-in -68.72, -16.52 -103.69, -14.86 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None TPO185,PTR187 TPO185,PTR187 XRAY 1.93 0.199 0.243 C 356.0 335.0 13 31 18 13 [[25, 313]] 1.0 4iza CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6Q7SA P28482 11 356 360.0 No_ligand No_ligand Inactive DFGin 6.871 16.4429 BLAminus -135.86, 178.78 64.53, 68.35 -89.93, 21.9 286.65, 77.96 -65.54, -26.51 out-out out 10.5018 Saltbr-out 6.046 HRD-in -71.72, -53.2 75.58, -1.79 out-in-out SNCoio in-out ActLoopNT-in 2.7387 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -104.24, -26.98 APE9-dihe-na -73.73, 160.8 APE8-dihe-in -64.49, 127.62 APE8-rot-in 314.27 APE67-dihe-in -62.97, -18.93 -54.09, -51.47 APE12-dist-out 14.2732 APE11-dist-in 10.9146 APE10-dist-in 7.0371 APE9-dist-in 4.3815 None None CME161 XRAY 1.73 0.186 0.24 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 6q7s CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6QA3A P28482 8 357 360.0 No_ligand No_ligand Inactive DFGin 6.7494 16.3488 BLAminus -133.97, 178.79 67.84, 69.02 -94.99, 25.64 290.82, 79.28 -65.46, -30.48 out-out out 10.4148 Saltbr-out 5.0254 HRD-in -72.38, -51.15 75.41, 2.05 out-in-out SNCoio in-out ActLoopNT-in 2.8304 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -89.93, -44.85 APE9-dihe-na -63.79, 161.45 APE8-dihe-in -63.48, 128.31 APE8-rot-in 312.79 APE67-dihe-in -66.51, -17.59 -56.23, -48.93 APE12-dist-out 14.0338 APE11-dist-in 10.7858 APE10-dist-in 6.456 APE9-dist-in 4.2118 None None CME161 XRAY 1.57 0.173 0.217 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 6qa3 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP2B P28482 12 357 360.0 No_ligand No_ligand Inactive DFGin 6.8869 16.0169 BLAminus -129.43, -178.45 61.61, 82.07 -103.18, 25.26 281.28, 72.06 -66.08, -26.0 in-in in 9.5302 Saltbr-in 3.519 HRD-in -78.87, -43.35 76.42, -19.49 in-in-out SNCiio in-out ActLoopNT-in 2.8623 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -170.24, 153.12 APE9-dihe-na -111.49, 162.96 APE8-dihe-in -53.17, 118.09 APE8-rot-in 309.96 APE67-dihe-in -60.93, -24.17 -46.56, -46.97 APE12-dist-in 10.876 APE11-dist-in 10.5581 APE10-dist-out 9.6191 APE9-dist-in 4.625 None None NEP125 XRAY 2.23 0.186 0.234 B 369.0 330.0 13 31 28 3 [[25, 313]] 1.0 4qp2 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7E73A P28482 11 357 360.0 No_ligand No_ligand Inactive DFGin 6.7923 16.3827 BLAminus -133.88, -176.67 61.49, 70.96 -87.72, 26.95 288.47, 77.24 -65.94, -21.97 out-out out 10.3623 Saltbr-out 5.6801 HRD-in -67.61, -54.59 76.14, -4.09 out-in-out SNCoio in-out ActLoopNT-in 2.8632 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -85.25, -42.65 APE9-dihe-na -64.83, 162.37 APE8-dihe-in -61.56, 126.65 APE8-rot-in 317.52 APE67-dihe-in -56.38, -21.26 -52.8, -49.77 APE12-dist-out 14.0621 APE11-dist-in 11.0447 APE10-dist-in 6.9322 APE9-dist-in 4.5385 Y36H None None XRAY 2.28 0.184 0.239 A 363.0 347.0 0 31 31 0 [[25, 313]] 1.0 7e73 CMGC_MAPK1_HUMAN CMGC 7.1e-85 290.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7E75A P28482 10 358 360.0 No_ligand No_ligand Inactive DFGin 6.8391 16.4398 BLAminus -129.94, 175.45 60.3, 73.29 -83.12, 28.79 286.11, 74.5 -66.51, -28.06 out-in out 10.0044 Saltbr-in 3.0244 HRD-in -70.35, -52.87 70.62, 5.79 in-in-out SNCiio in-out ActLoopNT-in 2.8305 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -89.48, -40.38 APE9-dihe-na -62.25, 159.89 APE8-dihe-in -57.08, 131.43 APE8-rot-in 306.44 APE67-dihe-in -67.44, -16.31 -58.81, -44.53 APE12-dist-out 14.6831 APE11-dist-in 10.9658 APE10-dist-in 6.9231 APE9-dist-in 4.2797 G37C None None XRAY 2.481 0.184 0.266 A 363.0 349.0 0 31 31 0 [[25, 313]] 1.0 7e75 CMGC_MAPK1_HUMAN CMGC 6.1e-85 291.0 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6D5YA P28482 13 357 360.0 No_ligand No_ligand Inactive DFGin 6.8579 15.5428 BLAminus -137.43, 179.95 53.71, 80.86 -100.16, 31.66 285.48, 74.31 -66.48, -38.27 in-out in 9.7266 Saltbr-out 5.958 HRD-in -69.56, -40.53 68.01, -18.75 out-in-out SNCoio in-out ActLoopNT-in 2.7783 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -140.18, 152.7 APE9-dihe-na -62.43, -38.47 APE8-dihe-in -149.63, 148.06 APE8-rot-out 181.82 APE67-dihe-in -68.03, -22.26 -116.51, 12.14 APE12-dist-in 8.1783 APE11-dist-in 11.6247 APE10-dist-out 9.0194 APE9-dist-out 11.3758 G169D None None XRAY 2.86 0.222 0.272 A 348.0 337.0 8 31 23 8 [[25, 313]] 1.0 6d5y CMGC_MAPK1_HUMAN CMGC 4.6e-84 288.1 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 1PMEA P28482 16 360 360.0 SB2:1001 Type1 Inactive DFGin 6.765 15.5071 BLAminus -135.95, -171.93 64.64, 69.47 -97.54, 30.49 287.85, 71.25 -67.06, -32.75 out-in out 10.0024 Saltbr-in 2.7294 HRD-in -72.65, -45.23 68.62, -0.37 in-in-out SNCiio in-out ActLoopNT-in 2.8378 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -84.16, -42.57 APE9-dihe-na -67.3, 161.57 APE8-dihe-in -53.65, 117.23 APE8-rot-in 314.74 APE67-dihe-in -59.87, -19.34 -44.9, -50.43 APE12-dist-out 14.2826 APE11-dist-in 10.9202 APE10-dist-in 6.4927 APE9-dist-in 4.4944 I103L,Q105T,D106H,E109G,T110A None CME161 XRAY 2.0 0.212 0.273 A 380.0 334.0 3 31 31 0 [[25, 313]] 1.0 1pme CMGC_MAPK1_HUMAN CMGC 2.9e-85 292.1 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6DMGA P28482 11 357 360.0 EK6:60407 Type1 Inactive DFGin 6.9203 15.5663 BLAminus -133.07, 178.36 60.69, 88.76 -105.82, 29.69 284.69, 69.92 -65.09, -32.16 in-in in 9.4717 Saltbr-in 2.6027 HRD-in -78.24, -51.26 73.1, 7.74 in-in-out SNCiio in-out ActLoopNT-in 2.7427 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.82, -45.49 APE9-dihe-na -55.71, 164.7 APE8-dihe-in -60.78, 135.16 APE8-rot-in 310.53 APE67-dihe-in -57.54, -17.33 -63.43, -50.83 APE12-dist-out 14.5009 APE11-dist-in 11.1823 APE10-dist-in 7.1809 APE9-dist-in 4.2649 None None CME161 XRAY 2.2 0.189 0.236 A 347.0 347.0 0 31 31 0 [[25, 313]] 1.0 6dmg CMGC_MAPK1_HUMAN CMGC 8.1e-86 293.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4XJ0A P28482 12 360 360.0 41B:401 Type1 Inactive DFGin 6.9253 15.9026 BLAminus -128.72, 178.82 60.25, 84.81 -99.58, 30.32 286.89, 68.04 -63.8, -36.34 in-in in 9.338 Saltbr-in 2.8027 HRD-in -71.71, -51.71 75.23, -2.58 in-in-out SNCiio in-out ActLoopNT-in 2.8054 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -96.68, -131.27 APE9-dihe-na -62.56, 169.56 APE8-dihe-in -72.46, 124.06 APE8-rot-in 293.95 APE67-dihe-in -61.54, -21.14 -31.5, -51.99 APE12-dist-in 8.838 APE11-dist-out 7.7911 APE10-dist-in 7.8669 APE9-dist-in 3.1529 None None NEP125 XRAY 2.58 0.21 0.244 A 349.0 346.0 1 31 31 0 [[25, 313]] 1.0 4xj0 CMGC_MAPK1_HUMAN CMGC 8.2e-86 293.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4XJ0B P28482 12 357 360.0 41B:401 Type1 Inactive DFGin 6.897 15.908 BLAminus -132.79, 176.01 57.28, 85.46 -101.01, 27.5 284.74, 71.93 -64.54, -32.65 in-in in 9.016 Saltbr-in 2.7424 HRD-in -73.78, -49.99 71.73, 4.29 in-in-out SNCiio in-out ActLoopNT-in 2.7122 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -89.81, -86.54 APE9-dihe-na -108.42, 172.18 APE8-dihe-in -68.23, 129.82 APE8-rot-in 294.66 APE67-dihe-in -55.14, -20.59 -34.58, -62.67 APE12-dist-in 8.6723 APE11-dist-out 7.6116 APE10-dist-in 7.8493 APE9-dist-in 3.3305 None None NEP125 XRAY 2.58 0.21 0.244 B 349.0 339.0 7 31 31 0 [[25, 313]] 1.0 4xj0 CMGC_MAPK1_HUMAN CMGC 8.2e-86 293.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8ZJVA P28482 10 358 360.0 5ID:401 Type1 Inactive DFGin 6.9106 15.0826 BLAminus -132.32, -178.04 60.39, 69.81 -88.48, 24.49 282.54, 65.61 -59.28, -29.83 in-out in 9.7237 Saltbr-out 3.8504 HRD-in -83.31, -48.81 74.28, 2.88 out-in-in SNCoii in-in ActLoopNT-in 2.7229 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.6, -35.66 APE9-dihe-na -57.94, 156.55 APE8-dihe-in -58.22, 132.29 APE8-rot-in 307.39 APE67-dihe-in -64.79, -16.64 -58.91, -47.39 APE12-dist-in 13.8364 APE11-dist-in 10.9358 APE10-dist-in 7.141 APE9-dist-in 4.3818 None None None XRAY 1.8 0.192 0.22 A 351.0 349.0 0 31 31 0 [[25, 313]] 1.0 8zjv CMGC_MAPK1_HUMAN CMGC 8.4e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5K4IA P28482 9 358 360.0 6QB:401 Type1 Inactive DFGin 6.9676 15.5827 BLAminus -128.06, 179.26 60.38, 84.38 -100.87, 21.25 280.37, 70.75 -56.14, -35.33 in-in in 9.1488 Saltbr-in 2.6594 HRD-in -74.77, -46.47 73.04, -3.13 in-in-out SNCiio in-out ActLoopNT-in 2.8063 ActLoopCT-out nonTYR APEdihe_aanio APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 29.58 APE8-rot-in 317.14 APE67-dihe-out -63.26, -26.15 54.49, -60.77 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.76 0.183 0.232 A 352.0 336.0 14 31 17 14 [[25, 313]] 1.0 5k4i CMGC_MAPK1_HUMAN CMGC 8.5e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 3SA0A P28482 4 360 360.0 NRA:361 Type1 Inactive DFGin 6.8096 16.4185 BLAminus -128.15, 173.53 68.16, 82.33 -100.92, 24.65 284.58, 80.45 -66.15, -21.66 out-in out 10.1959 Saltbr-in 3.3429 HRD-in -73.67, -49.24 75.15, -0.79 in-in-out SNCiio in-out ActLoopNT-in 2.8208 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.56, -33.19 APE9-dihe-na -68.73, 157.0 APE8-dihe-in -51.65, 125.57 APE8-rot-in 308.33 APE67-dihe-in -66.34, -15.84 -52.86, -49.01 APE12-dist-out 14.256 APE11-dist-in 10.9844 APE10-dist-in 6.9235 APE9-dist-in 4.3125 None None CME161,CME166,CME254 XRAY 1.595 0.166 0.2 A 360.0 357.0 0 31 31 0 [[25, 313]] 1.0 3sa0 CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FUXA P28482 11 357 360.0 E75:60401 Type1 Inactive DFGin 6.7827 16.3268 BLAminus -131.98, 173.23 64.18, 92.42 -107.28, 29.09 287.18, 73.2 -62.92, -25.19 out-out out 10.4355 Saltbr-out 4.0828 HRD-in -68.65, -47.69 68.98, -0.58 out-in-out SNCoio in-out ActLoopNT-in 2.8678 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.33, -33.1 APE9-dihe-na -65.65, 153.7 APE8-dihe-in -49.24, 122.29 APE8-rot-in 318.08 APE67-dihe-in -61.5, -20.64 -47.87, -51.2 APE12-dist-out 14.3562 APE11-dist-in 10.9667 APE10-dist-in 6.8625 APE9-dist-in 4.4037 None None CME161 XRAY 2.2 0.189 0.223 A 360.0 343.0 0 31 31 0 [[25, 313]] 1.0 4fux CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FUYA P28482 11 358 360.0 EK2:60401 Type1 Inactive DFGin 6.6881 16.2544 BLAminus -130.4, 175.2 67.86, 86.39 -101.47, 25.35 286.95, 80.76 -58.55, -28.93 out-out out 10.0232 Saltbr-out 3.7822 HRD-in -74.01, -47.63 67.29, 0.8 out-in-out SNCoio in-out ActLoopNT-in 2.7848 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -89.43, -38.85 APE9-dihe-na -63.21, 157.09 APE8-dihe-in -50.29, 121.79 APE8-rot-in 314.4 APE67-dihe-in -61.79, -22.74 -48.0, -50.77 APE12-dist-out 14.1648 APE11-dist-in 10.9 APE10-dist-in 6.7545 APE9-dist-in 4.3457 None None CME161,CME166,CME254 XRAY 2.0 0.19 0.217 A 360.0 332.0 6 31 31 0 [[25, 313]] 1.0 4fuy CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FV0A P28482 11 358 360.0 EK3:60401 Type1 Inactive DFGin 6.7016 16.5897 BLAminus -135.37, 177.45 64.31, 87.1 -103.53, 24.78 286.26, 83.38 -61.65, -32.0 out-out out 10.4133 Saltbr-out 5.0914 HRD-in -69.19, -51.99 72.25, -1.4 out-in-out SNCoio in-out ActLoopNT-in 2.7327 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.88, -31.2 APE9-dihe-na -67.61, 162.64 APE8-dihe-in -58.38, 116.74 APE8-rot-in 312.14 APE67-dihe-in -58.34, -24.84 -48.98, -48.23 APE12-dist-out 14.2516 APE11-dist-in 10.8272 APE10-dist-in 6.9036 APE9-dist-in 4.5028 None None CME161,CME166,CME254 XRAY 2.1 0.176 0.221 A 360.0 344.0 0 31 31 0 [[25, 313]] 1.0 4fv0 CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FV1A P28482 11 356 360.0 EK4:60401 Type1 Inactive DFGin 6.882 15.7881 BLAminus -128.65, -179.92 58.68, 89.27 -103.93, 26.87 282.58, 70.61 -62.53, -30.27 in-in in 9.6093 Saltbr-in 2.6382 HRD-in -70.74, -50.58 70.91, 3.53 in-in-out SNCiio in-out ActLoopNT-in 2.8164 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.48, -42.28 APE9-dihe-na -56.85, 152.08 APE8-dihe-in -48.18, 121.04 APE8-rot-in 315.61 APE67-dihe-in -60.27, -19.49 -50.25, -54.02 APE12-dist-out 14.5786 APE11-dist-in 11.2844 APE10-dist-in 7.3103 APE9-dist-in 4.3863 None None CME161 XRAY 1.99 0.182 0.225 A 360.0 343.0 0 31 31 0 [[25, 313]] 1.0 4fv1 CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FV2A P28482 11 357 360.0 EK5:60401 Type1 Inactive DFGin 6.9282 15.5747 BLAminus -125.87, 177.7 60.4, 91.72 -106.05, 22.47 282.22, 72.48 -61.11, -31.38 in-in in 9.6139 Saltbr-in 2.6501 HRD-in -73.27, -50.24 71.89, 6.48 in-in-out SNCiio in-out ActLoopNT-in 2.8463 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.13, -41.13 APE9-dihe-na -56.8, 151.84 APE8-dihe-in -51.06, 121.97 APE8-rot-in 312.92 APE67-dihe-in -60.07, -18.44 -50.57, -54.42 APE12-dist-out 14.5319 APE11-dist-in 11.2599 APE10-dist-in 7.1809 APE9-dist-in 4.2534 None None CME161 XRAY 2.0 0.181 0.211 A 360.0 345.0 0 31 31 0 [[25, 313]] 1.0 4fv2 CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FV3A P28482 11 357 360.0 EK6:60401 Type1 Inactive DFGin 6.9204 15.5434 BLAminus -128.41, 176.81 62.18, 92.27 -108.69, 28.96 282.46, 73.53 -64.35, -33.27 in-in in 9.4958 Saltbr-in 2.5965 HRD-in -72.39, -48.68 68.34, 4.53 in-in-out SNCiio in-out ActLoopNT-in 2.7992 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.4, -45.32 APE9-dihe-na -52.9, 153.24 APE8-dihe-in -50.54, 121.86 APE8-rot-in 314.89 APE67-dihe-in -54.54, -21.53 -50.33, -56.04 APE12-dist-out 14.5535 APE11-dist-in 11.0404 APE10-dist-in 7.1133 APE9-dist-in 4.3325 None None CME161 XRAY 2.2 0.194 0.236 A 360.0 347.0 0 31 31 0 [[25, 313]] 1.0 4fv3 CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FV7A P28482 11 358 360.0 E94:60401 Type1 Inactive DFGin 6.7505 15.2985 BLAminus -131.38, 170.76 61.08, 92.51 -98.87, 27.02 282.81, 83.46 -61.79, -27.94 in-in in 9.3476 Saltbr-in 2.7299 HRD-in -71.48, -49.08 72.62, -5.62 in-in-out SNCiio in-out ActLoopNT-in 2.8176 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -84.4, -37.98 APE9-dihe-na -73.15, 158.52 APE8-dihe-in -50.31, 121.34 APE8-rot-in 315.03 APE67-dihe-in -59.69, -17.96 -45.2, -57.15 APE12-dist-out 14.146 APE11-dist-in 10.9845 APE10-dist-in 6.5536 APE9-dist-in 4.424 None None CME161,CME254 XRAY 1.9 0.184 0.208 A 360.0 344.0 0 31 31 0 [[25, 313]] 1.0 4fv7 CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4G6NA P28482 11 358 360.0 EK0:60401 Type1 Inactive DFGin 6.8123 16.1652 BLAminus -131.25, -179.75 63.09, 82.17 -100.91, 24.89 285.94, 74.26 -63.08, -24.54 out-out out 10.274 Saltbr-out 4.4022 HRD-in -69.01, -50.25 70.2, 2.18 out-in-out SNCoio in-out ActLoopNT-in 2.8284 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -87.99, -49.88 APE9-dihe-na -51.77, 152.56 APE8-dihe-in -49.69, 121.96 APE8-rot-in 318.5 APE67-dihe-in -61.88, -19.83 -49.94, -50.95 APE12-dist-out 14.4497 APE11-dist-in 11.0166 APE10-dist-in 6.8261 APE9-dist-in 4.3111 None None CME161 XRAY 2.0 0.189 0.225 A 360.0 342.0 0 31 31 0 [[25, 313]] 1.0 4g6n CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4G6OA P28482 11 357 360.0 E28:60401 Type1 Inactive DFGin 6.8676 15.7672 BLAminus -132.32, 171.16 68.07, 92.69 -108.93, 25.2 285.69, 75.37 -63.05, -29.38 in-in in 9.8751 Saltbr-in 2.6091 HRD-in -73.49, -49.08 71.04, 5.76 in-in-out SNCiio in-out ActLoopNT-in 2.87 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -94.79, -39.82 APE9-dihe-na -57.3, 151.65 APE8-dihe-in -47.93, 121.54 APE8-rot-in 314.11 APE67-dihe-in -59.01, -19.0 -49.51, -52.55 APE12-dist-out 14.5085 APE11-dist-in 11.0806 APE10-dist-in 7.0605 APE9-dist-in 4.3423 None None CME161,CME254 XRAY 2.2 0.182 0.226 A 360.0 341.0 2 31 31 0 [[25, 313]] 1.0 4g6o CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4N0SA P28482 6 357 360.0 DHC:401 Type1 Inactive DFGin 6.8229 16.2444 BLAminus -128.69, 171.78 67.96, 85.58 -103.3, 23.69 285.91, 81.72 -64.56, -25.09 in-in in 9.7872 Saltbr-in 2.5676 HRD-in -74.15, -53.22 76.21, 1.31 in-in-out SNCiio in-out ActLoopNT-in 2.8026 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.19, -38.38 APE9-dihe-na -61.29, 155.86 APE8-dihe-in -51.16, 125.28 APE8-rot-in 310.76 APE67-dihe-in -61.05, -17.42 -53.27, -52.48 APE12-dist-out 14.3991 APE11-dist-in 11.1017 APE10-dist-in 7.0324 APE9-dist-in 4.2673 None None CME65,CME161,CME166,CME254 XRAY 1.799 0.156 0.189 A 360.0 352.0 0 31 31 0 [[25, 313]] 1.0 4n0s CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4ZXTA P28482 7 357 360.0 CAQ:401 Type1 Inactive DFGin 6.7009 16.3505 BLAminus -130.15, 172.75 68.13, 81.0 -97.66, 27.23 286.93, 81.73 -67.09, -23.48 in-in in 9.8851 Saltbr-in 3.0666 HRD-in -74.52, -53.3 74.8, -0.36 in-in-out SNCiio in-out ActLoopNT-in 2.7631 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -90.15, -37.46 APE9-dihe-na -64.75, 157.78 APE8-dihe-in -51.68, 126.67 APE8-rot-in 310.04 APE67-dihe-in -65.57, -16.47 -57.13, -47.67 APE12-dist-out 14.2841 APE11-dist-in 10.9411 APE10-dist-in 6.8704 APE9-dist-in 4.342 None None CME161,CME166,CME254 XRAY 2.0 0.155 0.183 A 360.0 351.0 0 31 31 0 [[25, 313]] 1.0 4zxt CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5LCKA P28482 11 357 360.0 6TT:405 Type1 Inactive DFGin 6.833 16.3617 BLAminus -131.32, 176.11 61.41, 85.37 -98.86, 24.24 288.14, 70.28 -64.0, -28.03 out-in out 10.1133 Saltbr-in 3.1384 HRD-in -71.06, -50.82 73.25, -0.73 in-in-out SNCiio in-out ActLoopNT-in 2.7479 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.15, -42.62 APE9-dihe-na -61.49, 157.76 APE8-dihe-in -63.32, 126.75 APE8-rot-in 312.53 APE67-dihe-in -62.37, -18.92 -55.45, -50.31 APE12-dist-out 14.5531 APE11-dist-in 11.1154 APE10-dist-in 6.948 APE9-dist-in 4.2426 None None CME127,CME161 XRAY 1.89 0.166 0.212 A 360.0 347.0 0 31 31 0 [[25, 313]] 1.0 5lck CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5LCJA P28482 11 357 360.0 6TS:401 Type1 Inactive DFGin 6.8566 16.3984 BLAminus -133.84, 179.61 58.41, 84.49 -97.23, 19.15 287.32, 73.24 -57.76, -29.68 in-in in 9.7875 Saltbr-in 2.7292 HRD-in -70.75, -48.77 69.94, 3.32 in-in-out SNCiio in-out ActLoopNT-in 2.7887 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.15, -43.92 APE9-dihe-na -60.16, 161.13 APE8-dihe-in -68.17, 127.19 APE8-rot-in 313.62 APE67-dihe-in -59.22, -20.63 -49.4, -54.81 APE12-dist-out 14.526 APE11-dist-in 11.1857 APE10-dist-in 6.9331 APE9-dist-in 4.0678 None None CME161 XRAY 1.78 0.165 0.212 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 5lcj CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G91A P28482 8 357 360.0 EQW:403 Type1 Inactive DFGin 6.833 16.2128 BLAminus -129.12, 173.4 66.9, 86.58 -102.5, 23.7 285.8, 73.37 -66.86, -28.43 in-in in 9.8484 Saltbr-in 2.7089 HRD-in -71.91, -52.82 75.11, 8.05 in-in-out SNCiio in-out ActLoopNT-in 2.7922 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -94.42, -34.41 APE9-dihe-na -72.71, 166.97 APE8-dihe-in -70.09, 128.2 APE8-rot-in 306.07 APE67-dihe-in -65.08, -18.81 -53.56, -48.36 APE12-dist-out 14.5035 APE11-dist-in 11.1854 APE10-dist-in 6.9758 APE9-dist-in 4.1663 None None CME161 XRAY 1.8 0.169 0.22 A 368.0 345.0 0 31 31 0 [[25, 313]] 1.0 6g91 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G92A P28482 8 357 360.0 ERZ:404 Type1 Inactive DFGin 6.7948 16.0099 BLAminus -129.08, 178.13 66.15, 83.92 -102.64, 21.66 286.21, 77.45 -65.22, -27.45 out-in out 10.0858 Saltbr-in 2.9853 HRD-in -67.98, -54.58 72.32, 6.81 in-in-out SNCiio in-out ActLoopNT-in 2.7273 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.78, -39.98 APE9-dihe-na -69.58, 164.27 APE8-dihe-in -62.75, 127.33 APE8-rot-in 313.21 APE67-dihe-in -68.69, -16.41 -55.06, -45.14 APE12-dist-out 14.6322 APE11-dist-in 11.199 APE10-dist-in 7.0093 APE9-dist-in 4.3113 None None CME161 XRAY 1.99 0.167 0.227 A 368.0 344.0 0 31 31 0 [[25, 313]] 1.0 6g92 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G93A P28482 11 357 360.0 EU2:406 Type1 Inactive DFGin 6.861 15.416 BLAminus -128.45, 175.41 69.18, 82.85 -99.46, 27.42 281.6, 77.67 -68.16, -23.82 in-in in 9.5572 Saltbr-in 2.714 HRD-in -71.99, -50.41 73.92, 2.92 in-in-out SNCiio in-out ActLoopNT-in 2.8277 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -88.24, -36.27 APE9-dihe-na -73.61, 165.11 APE8-dihe-in -63.24, 129.83 APE8-rot-in 308.21 APE67-dihe-in -64.06, -18.71 -58.14, -46.82 APE12-dist-out 14.494 APE11-dist-in 11.2615 APE10-dist-in 6.8314 APE9-dist-in 4.2491 None None CME161 XRAY 1.67 0.173 0.213 A 368.0 344.0 0 31 31 0 [[25, 313]] 1.0 6g93 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G97A P28482 11 357 360.0 EQZ:407 Type1 Inactive DFGin 6.7002 14.938 BLAminus -125.84, -179.56 61.12, 78.12 -92.48, 23.09 286.69, 78.92 -62.72, -27.99 in-in in 9.1734 Saltbr-in 2.7708 HRD-in -75.99, -51.88 76.88, 3.3 in-in-out SNCiio in-out ActLoopNT-in 2.7191 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.17, -31.33 APE9-dihe-na -65.13, 158.09 APE8-dihe-in -55.46, 126.0 APE8-rot-in 305.91 APE67-dihe-in -65.76, -19.34 -57.25, -45.19 APE12-dist-out 14.4133 APE11-dist-in 11.1867 APE10-dist-in 7.4123 APE9-dist-in 4.4174 None None CME161 XRAY 1.9 0.164 0.223 A 368.0 345.0 0 31 31 0 [[25, 313]] 1.0 6g97 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G9AA P28482 8 357 360.0 ESQ:404 Type1 Inactive DFGin 6.809 15.7486 BLAminus -133.55, 175.54 70.21, 80.12 -98.94, 35.97 283.37, 75.29 -74.82, -27.7 in-in in 9.5939 Saltbr-in 2.7217 HRD-in -73.03, -53.33 75.02, 8.47 in-in-out SNCiio in-out ActLoopNT-in 2.7794 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.87, -26.44 APE9-dihe-na -77.35, 160.11 APE8-dihe-in -55.77, 127.56 APE8-rot-in 307.22 APE67-dihe-in -65.89, -20.78 -58.13, -41.92 APE12-dist-out 14.379 APE11-dist-in 11.1123 APE10-dist-in 6.9367 APE9-dist-in 4.2263 None None CME161 XRAY 1.91 0.182 0.25 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 6g9a CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G9MA P28482 11 356 360.0 ESW:404 Type1 Inactive DFGin 6.7926 16.1252 BLAminus -130.4, 178.4 64.83, 86.11 -105.98, 21.48 280.05, 78.72 -67.32, -25.7 in-in in 9.8972 Saltbr-in 2.6957 HRD-in -72.12, -52.61 74.73, 0.78 in-in-out SNCiio in-out ActLoopNT-in 2.8267 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -89.95, -41.88 APE9-dihe-na -68.93, 161.07 APE8-dihe-in -54.0, 127.27 APE8-rot-in 310.85 APE67-dihe-in -66.49, -16.25 -58.19, -47.4 APE12-dist-out 14.6239 APE11-dist-in 11.2459 APE10-dist-in 7.1339 APE9-dist-in 4.4408 None None CME161 XRAY 1.86 0.16 0.206 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 6g9m CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6GDQA P28482 10 357 360.0 EVK:407 Type1 Inactive DFGin 6.8906 15.0859 BLAminus -121.36, 176.04 66.05, 86.82 -103.12, 27.78 283.55, 74.24 -70.02, -23.75 in-in in 9.4567 Saltbr-in 2.7494 HRD-in -75.22, -50.5 75.66, 3.76 in-in-out SNCiio in-out ActLoopNT-in 2.8668 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.91, -37.76 APE9-dihe-na -66.69, 161.06 APE8-dihe-in -59.55, 129.43 APE8-rot-in 308.79 APE67-dihe-in -60.08, -19.42 -59.96, -47.92 APE12-dist-out 14.6395 APE11-dist-in 11.2664 APE10-dist-in 7.105 APE9-dist-in 4.266 None None CME161 XRAY 1.86 0.183 0.226 A 368.0 340.0 0 31 31 0 [[25, 313]] 1.0 6gdq CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6GJBA P28482 8 357 360.0 F0H:406 Type1 Inactive DFGin 6.8368 16.293 BLAminus -126.98, 179.07 63.86, 85.36 -103.53, 21.34 281.07, 75.2 -67.74, -24.46 in-in in 9.8373 Saltbr-in 2.7014 HRD-in -74.2, -47.41 71.12, 5.16 in-in-out SNCiio in-out ActLoopNT-in 2.8482 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.51, -37.65 APE9-dihe-na -68.71, 167.6 APE8-dihe-in -73.02, 127.9 APE8-rot-in 308.91 APE67-dihe-in -62.78, -17.85 -56.2, -48.74 APE12-dist-out 14.6185 APE11-dist-in 11.2287 APE10-dist-in 7.1226 APE9-dist-in 4.3012 None None CME161 XRAY 1.82 0.166 0.206 A 368.0 348.0 0 31 31 0 [[25, 313]] 1.0 6gjb CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6Q7KA P28482 8 357 360.0 2AI:402 Type1 Inactive DFGin 6.632 16.3302 BLAminus -133.8, 178.83 63.78, 79.31 -92.04, 27.48 287.22, 82.56 -61.45, -34.33 out-out out 10.1956 Saltbr-out 6.1197 HRD-in -75.78, -49.45 68.06, 4.85 out-in-in SNCoii in-in ActLoopNT-in 2.7578 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -100.75, -11.98 APE9-dihe-na -70.17, 165.14 APE8-dihe-in -64.85, 129.41 APE8-rot-in 320.27 APE67-dihe-in -61.77, -17.43 -50.8, -55.55 APE12-dist-in 13.7347 APE11-dist-in 10.5228 APE10-dist-in 7.4955 APE9-dist-in 4.4751 None None CME161 XRAY 1.84 0.214 0.263 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 6q7k CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6QAWA P28482 11 357 360.0 HVE:402 Type1 Inactive DFGin 6.8864 16.4273 BLAminus -130.86, 178.03 65.32, 83.3 -102.82, 19.54 284.49, 77.56 -61.13, -26.51 out-in out 10.5368 Saltbr-in 2.7518 HRD-in -70.95, -54.2 74.28, 5.68 in-in-out SNCiio in-out ActLoopNT-in 2.738 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.95, -38.46 APE9-dihe-na -64.02, 161.82 APE8-dihe-in -69.45, 129.99 APE8-rot-in 309.38 APE67-dihe-in -65.8, -13.89 -55.83, -49.38 APE12-dist-out 14.4256 APE11-dist-in 11.2095 APE10-dist-in 7.0542 APE9-dist-in 4.168 None None CME127,CME161 XRAY 1.84 0.176 0.221 A 368.0 338.0 0 31 31 0 [[25, 313]] 1.0 6qaw CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6RQ4A P28482 19 357 360.0 KE8:402 Type1 Inactive DFGin 6.8474 15.9698 BLAminus -128.54, 178.3 64.79, 78.45 -100.16, 26.93 286.26, 70.97 -73.15, -19.61 out-in out 10.0359 Saltbr-in 2.8212 HRD-in -71.88, -50.45 75.67, 1.9 in-in-out SNCiio in-out ActLoopNT-in 2.8269 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -101.27, -34.28 APE9-dihe-na -68.61, 157.72 APE8-dihe-in -49.0, 128.91 APE8-rot-in 310.29 APE67-dihe-in -57.21, -20.43 -61.38, -50.93 APE12-dist-out 14.3023 APE11-dist-in 11.0143 APE10-dist-in 7.0236 APE9-dist-in 4.3086 None None CME161 XRAY 1.96 0.178 0.232 A 368.0 332.0 0 31 31 0 [[25, 313]] 1.0 6rq4 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7NR3A P28482 11 356 360.0 UO5:403 Type1 Inactive DFGin 6.9245 16.0971 BLAminus -130.06, 178.7 64.56, 85.28 -102.95, 23.54 283.45, 75.36 -71.31, -27.37 in-in in 9.5862 Saltbr-in 2.6938 HRD-in -69.68, -49.47 70.56, 8.46 in-in-out SNCiio in-out ActLoopNT-in 2.8179 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.95, -33.96 APE9-dihe-na -70.24, 164.84 APE8-dihe-in -69.84, 133.41 APE8-rot-in 308.31 APE67-dihe-in -61.04, -17.03 -62.39, -48.06 APE12-dist-out 14.5567 APE11-dist-in 11.1809 APE10-dist-in 7.047 APE9-dist-in 4.183 None None CME161 XRAY 1.897 0.186 0.236 A 368.0 337.0 0 31 31 0 [[25, 313]] 1.0 7nr3 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AO2A P28482 13 357 360.0 NXI:403 Type1 Inactive DFGin 6.9737 16.0872 BLAminus -127.0, 175.32 65.42, 90.96 -103.32, 20.32 287.87, 77.93 -68.75, -24.84 out-in out 10.1829 Saltbr-in 2.5466 HRD-in -71.83, -49.59 70.69, 9.06 in-in-out SNCiio in-out ActLoopNT-in 2.8169 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -120.49, 145.2 APE9-dihe-na 68.78, 172.76 APE8-dihe-in -86.31, 144.9 APE8-rot-in 292.42 APE67-dihe-in -64.12, -21.4 -51.53, -50.75 APE12-dist-in 13.5871 APE11-dist-in 11.3878 APE10-dist-out 8.9602 APE9-dist-in 3.2191 None None CME161 XRAY 1.796 0.172 0.219 A 368.0 341.0 0 31 31 0 [[25, 313]] 1.0 8ao2 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AO3A P28482 11 357 360.0 NYX:403 Type1 Inactive DFGin 6.9386 16.0931 BLAminus -132.25, 175.07 64.16, 87.67 -100.11, 18.89 284.96, 74.3 -61.41, -29.58 out-in out 10.3479 Saltbr-in 2.8108 HRD-in -70.24, -51.94 74.04, 4.8 in-in-out SNCiio in-out ActLoopNT-in 2.8188 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.46, -38.87 APE9-dihe-na -66.82, 162.01 APE8-dihe-in -63.69, 123.72 APE8-rot-in 311.7 APE67-dihe-in -65.35, -15.16 -54.01, -48.2 APE12-dist-out 14.5798 APE11-dist-in 11.2081 APE10-dist-in 7.1645 APE9-dist-in 4.2345 None None CME127,CME161 XRAY 1.778 0.171 0.209 A 368.0 339.0 0 31 31 0 [[25, 313]] 1.0 8ao3 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AO4A P28482 11 357 360.0 N8U:404 Type1 Inactive DFGin 6.9526 16.1498 BLAminus -127.45, 178.22 65.53, 84.35 -97.67, 21.24 287.61, 71.09 -68.52, -22.12 out-in out 10.2614 Saltbr-in 2.6533 HRD-in -73.4, -50.97 71.89, 8.15 in-in-out SNCiio in-out ActLoopNT-in 2.7639 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.16, -34.31 APE9-dihe-na -67.02, 162.42 APE8-dihe-in -69.78, 130.09 APE8-rot-in 307.95 APE67-dihe-in -63.57, -16.58 -55.88, -49.8 APE12-dist-out 14.5358 APE11-dist-in 11.2093 APE10-dist-in 7.2444 APE9-dist-in 4.1632 None None CME127,CME161 XRAY 1.825 0.176 0.222 A 368.0 339.0 0 31 31 0 [[25, 313]] 1.0 8ao4 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AO5A P28482 15 356 360.0 N6K:404 Type1 Inactive DFGin 6.7799 16.2441 BLAminus -133.08, 178.76 65.02, 81.87 -99.24, 26.92 285.8, 73.59 -67.79, -20.29 out-in out 10.3488 Saltbr-in 2.677 HRD-in -70.06, -53.33 72.08, 4.5 in-in-out SNCiio in-out ActLoopNT-in 2.7825 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -90.81, -42.59 APE9-dihe-na -66.23, 157.78 APE8-dihe-in -48.65, 124.73 APE8-rot-in 313.04 APE67-dihe-in -61.1, -18.16 -56.92, -48.04 APE12-dist-out 14.5387 APE11-dist-in 11.1572 APE10-dist-in 7.0251 APE9-dist-in 4.3235 None None CME161 XRAY 1.595 0.182 0.214 A 368.0 330.0 3 31 31 0 [[25, 313]] 1.0 8ao5 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AO6A P28482 11 356 360.0 N9F:406 Type1 Inactive DFGin 6.7709 16.337 BLAminus -129.81, 177.88 71.62, 78.81 -103.22, 23.44 283.23, 73.97 -64.0, -29.38 out-in out 10.3714 Saltbr-in 2.597 HRD-in -72.45, -50.74 72.14, 4.83 in-in-out SNCiio in-out ActLoopNT-in 2.7853 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.92, -36.24 APE9-dihe-na -66.98, 156.39 APE8-dihe-in -51.35, 125.27 APE8-rot-in 311.93 APE67-dihe-in -64.42, -17.18 -56.32, -47.54 APE12-dist-out 14.4141 APE11-dist-in 11.1069 APE10-dist-in 7.1029 APE9-dist-in 4.2638 None None CME127,CME161 XRAY 1.811 0.175 0.222 A 368.0 338.0 0 31 31 0 [[25, 313]] 1.0 8ao6 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AO7A P28482 11 356 360.0 N3X:405 Type1 Inactive DFGin 6.7103 16.4925 BLAminus -130.29, 175.2 63.99, 83.71 -99.06, 20.5 284.28, 78.44 -62.72, -26.91 out-in out 10.0995 Saltbr-in 2.8326 HRD-in -69.87, -51.12 72.22, 5.22 in-in-out SNCiio in-out ActLoopNT-in 2.8002 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.64, -38.24 APE9-dihe-na -67.32, 159.83 APE8-dihe-in -59.65, 128.33 APE8-rot-in 309.86 APE67-dihe-in -62.17, -17.84 -57.44, -48.08 APE12-dist-out 14.6174 APE11-dist-in 11.203 APE10-dist-in 7.1777 APE9-dist-in 4.241 None None CME161 XRAY 1.61 0.18 0.213 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 8ao7 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AO8A P28482 11 356 360.0 N5U:404 Type1 Inactive DFGin 6.8404 16.2541 BLAminus -124.47, 159.94 66.97, 91.28 -101.17, 23.74 286.55, 70.97 -69.86, -26.55 out-in out 10.186 Saltbr-in 2.777 HRD-in -73.33, -50.93 73.69, 3.86 in-in-out SNCiio in-out ActLoopNT-in 2.844 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.88, -36.2 APE9-dihe-na -74.28, 161.44 APE8-dihe-in -60.31, 128.44 APE8-rot-in 313.77 APE67-dihe-in -60.66, -18.48 -57.92, -51.15 APE12-dist-out 14.5766 APE11-dist-in 11.2776 APE10-dist-in 6.9297 APE9-dist-in 4.2436 None None CME161 XRAY 1.697 0.174 0.211 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 8ao8 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AO9A P28482 11 356 360.0 N4F:406 Type1 Inactive DFGin 6.837 16.4502 BLAminus -129.5, 178.83 61.88, 81.37 -96.97, 21.21 286.14, 78.83 -59.7, -30.7 out-out out 10.3006 Saltbr-out 3.7652 HRD-in -72.95, -49.65 72.84, 3.98 out-in-out SNCoio in-out ActLoopNT-in 2.8539 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.06, -44.4 APE9-dihe-na -60.28, 156.59 APE8-dihe-in -55.09, 130.24 APE8-rot-in 307.62 APE67-dihe-in -64.58, -17.09 -62.44, -44.52 APE12-dist-out 14.2701 APE11-dist-in 10.9807 APE10-dist-in 6.7892 APE9-dist-in 4.2298 None None CME161 XRAY 1.624 0.184 0.232 A 368.0 338.0 2 31 31 0 [[25, 313]] 1.0 8ao9 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AOBA P28482 18 356 360.0 NB3:403 Type1 Inactive DFGin 6.7516 16.1645 BLAminus -128.36, 178.48 65.28, 86.43 -100.71, 25.07 286.34, 74.77 -65.61, -24.15 out-in out 10.1005 Saltbr-in 2.983 HRD-in -71.47, -50.97 71.51, 5.75 in-in-out SNCiio in-out ActLoopNT-in 2.8095 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -94.09, -39.14 APE9-dihe-na -64.67, 155.77 APE8-dihe-in -48.32, 123.77 APE8-rot-in 313.88 APE67-dihe-in -63.98, -17.45 -56.05, -46.79 APE12-dist-out 14.4705 APE11-dist-in 11.1245 APE10-dist-in 7.1389 APE9-dist-in 4.3045 None None CME161 XRAY 1.623 0.19 0.219 A 368.0 321.0 9 31 31 0 [[25, 313]] 1.0 8aob CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AOCA P28482 11 356 360.0 N3O:404 Type1 Inactive DFGin 6.8078 16.5641 BLAminus -134.22, 176.12 61.31, 83.78 -95.87, 22.58 287.89, 72.74 -61.25, -30.2 out-in out 10.0676 Saltbr-in 2.9852 HRD-in -68.58, -52.47 76.18, -0.03 in-in-out SNCiio in-out ActLoopNT-in 2.805 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.04, -39.01 APE9-dihe-na -66.54, 160.54 APE8-dihe-in -60.46, 127.52 APE8-rot-in 307.48 APE67-dihe-in -65.27, -16.19 -57.34, -47.83 APE12-dist-out 14.4223 APE11-dist-in 11.1654 APE10-dist-in 6.9827 APE9-dist-in 4.2503 None None CME161,CME254 XRAY 1.62 0.18 0.217 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 8aoc CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AOEA P28482 11 356 360.0 N6U:404 Type1 Inactive DFGin 6.8456 16.2819 BLAminus -132.37, -178.87 58.37, 82.96 -99.09, 25.19 287.98, 69.56 -66.93, -25.42 out-in out 10.3904 Saltbr-in 2.8304 HRD-in -67.93, -53.19 72.31, 4.69 in-in-out SNCiio in-out ActLoopNT-in 2.8513 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -92.48, -40.8 APE9-dihe-na -62.56, 159.15 APE8-dihe-in -56.43, 129.3 APE8-rot-in 309.56 APE67-dihe-in -62.42, -18.54 -61.43, -45.9 APE12-dist-out 14.4693 APE11-dist-in 11.1035 APE10-dist-in 7.0696 APE9-dist-in 4.286 None None CME161 XRAY 1.687 0.188 0.23 A 368.0 337.0 9 31 31 0 [[25, 313]] 1.0 8aoe CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AOFA P28482 11 356 360.0 N4U:404 Type1 Inactive DFGin 6.7815 16.4051 BLAminus -132.51, 174.94 63.69, 84.19 -96.49, 22.47 287.54, 73.86 -62.42, -28.19 out-in out 10.0276 Saltbr-in 2.694 HRD-in -71.23, -49.41 73.98, 2.59 in-in-out SNCiio in-out ActLoopNT-in 2.8233 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.09, -36.54 APE9-dihe-na -68.25, 159.72 APE8-dihe-in -59.27, 130.06 APE8-rot-in 309.47 APE67-dihe-in -63.72, -17.26 -60.16, -47.14 APE12-dist-out 14.2985 APE11-dist-in 11.0495 APE10-dist-in 6.8308 APE9-dist-in 4.213 None None CME161 XRAY 1.615 0.176 0.218 A 368.0 341.0 5 31 31 0 [[25, 313]] 1.0 8aof CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AOJA P28482 10 356 360.0 N8L:407 Type1 Inactive DFGin 6.8369 16.082 BLAminus -127.69, 169.46 70.05, 82.88 -97.45, 30.61 290.22, 67.33 -76.11, -5.52 in-in in 9.8535 Saltbr-in 2.8552 HRD-in -74.88, -52.62 76.87, 1.14 in-in-out SNCiio in-out ActLoopNT-in 2.8419 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -90.16, -32.1 APE9-dihe-na -79.1, 161.85 APE8-dihe-in -53.19, 128.47 APE8-rot-in 308.92 APE67-dihe-in -65.83, -16.72 -55.59, -45.91 APE12-dist-out 14.2864 APE11-dist-in 11.0395 APE10-dist-in 6.668 APE9-dist-in 4.4124 None None CME161 XRAY 1.12 0.18 0.203 A 368.0 340.0 0 31 31 0 [[25, 313]] 1.0 8aoj CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 3W55A P28482 11 357 360.0 1FM:401 Type1 Inactive DFGin 6.8453 15.3111 BLAminus -114.5, 159.86 66.42, 121.73 -134.68, 25.56 281.37, 73.75 -67.05, -27.15 in-in in 9.7658 Saltbr-in 3.3276 HRD-in -73.73, -41.19 69.72, -22.0 in-in-out SNCiio in-out ActLoopNT-in 3.2448 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_nnoo APE10-dihe-na 999.0, 108.71 APE9-dihe-na 148.35, -177.22 APE8-dihe-out -15.28, -98.64 APE8-rot-out 164.29 APE67-dihe-out -92.01, -3.61 134.93, -62.27 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 10.0062 APE9-dist-out 7.3671 None None None XRAY 3.0 0.277 0.281 A 368.0 335.0 12 31 19 12 [[25, 313]] 1.0 3w55 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5AX3A P28482 10 358 360.0 5ID:60401 Type1 Inactive DFGin 7.0825 16.4278 BLAminus -127.71, -158.49 57.95, 57.37 -96.01, 22.02 283.93, 97.26 -69.96, -43.04 out-out out 10.3799 Saltbr-out 5.4612 HRD-in -80.67, -26.64 62.8, -46.45 out-in-out SNCoio in-out ActLoopNT-in 2.6796 ActLoopCT-out nonTYR APEdihe_aanii APEdist_iion APE10-dihe-na -119.6, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 86.51 APE8-rot-in 343.49 APE67-dihe-in -91.22, -8.7 -96.21, 42.35 APE12-dist-in 8.4834 APE11-dist-in 9.8124 APE10-dist-out 9.5116 APE9-dist-none 999.0 None None None XRAY 2.984 0.239 0.285 A 368.0 329.0 20 31 22 9 [[25, 313]] 1.0 5ax3 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7W5OA P28482 11 360 360.0 5ID:401 Type1 Inactive DFGin 6.7259 16.0736 BLAminus -134.06, -178.68 57.89, 83.45 -97.58, 26.47 285.78, 74.05 -62.2, -23.74 in-out in 9.5977 Saltbr-out 3.6644 HRD-in -64.25, -57.62 81.95, -6.27 out-in-out SNCoio in-out ActLoopNT-in 2.8418 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -125.26, 105.21 APE9-dihe-na 77.53, 139.94 APE8-dihe-in -62.13, 139.76 APE8-rot-in 304.97 APE67-dihe-in -67.0, -21.21 -48.23, -45.39 APE12-dist-in 8.898 APE11-dist-out 7.5203 APE10-dist-in 7.6672 APE9-dist-in 3.0549 None None NEP125 XRAY 2.35 0.228 0.279 A 368.0 350.0 0 31 31 0 [[25, 313]] 1.0 7w5o CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7XC1B P28482 12 357 360.0 5ID:402 Type1 Inactive DFGin 6.7495 15.8478 BLAminus -136.86, 178.87 56.25, 81.89 -92.76, 18.78 288.3, 68.54 -60.11, -21.88 in-in in 9.1742 Saltbr-in 3.022 HRD-in -76.63, -53.91 78.34, 9.0 in-in-out SNCiio in-out ActLoopNT-in 2.7077 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -112.15, 106.32 APE9-dihe-na 73.8, 141.03 APE8-dihe-in -61.74, 138.85 APE8-rot-in 297.46 APE67-dihe-in -56.69, -24.12 -44.69, -58.48 APE12-dist-in 8.3558 APE11-dist-out 7.5573 APE10-dist-in 7.8496 APE9-dist-in 3.0354 None None NEP125 XRAY 2.09 0.232 0.271 B 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 7xc1 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4O6EA P28482 13 357 360.0 2SH:401 Type1 Inactive DFGin 6.9793 16.0643 BLAminus -129.07, 179.57 59.4, 82.21 -100.26, 25.66 282.82, 72.21 -58.83, -35.99 in-in in 9.3168 Saltbr-in 2.7894 HRD-in -71.69, -45.65 70.14, -2.53 in-in-out SNCiio in-out ActLoopNT-in 2.7687 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 128.7 APE9-dihe-na -71.46, -32.14 APE8-dihe-in -151.2, 142.21 APE8-rot-out 186.25 APE67-dihe-in -63.05, -17.07 -112.45, 9.16 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.3381 APE9-dist-out 11.0791 None None None XRAY 1.95 0.223 0.223 A 368.0 328.0 14 31 20 11 [[25, 313]] 1.0 4o6e CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP1A P28482 12 360 360.0 EMU:401 Type1 Inactive DFGin 6.9626 16.2282 BLAminus -131.47, 175.74 65.18, 79.32 -100.68, 29.14 286.53, 66.72 -63.4, -33.69 out-out out 10.0382 Saltbr-out 3.9837 HRD-in -69.26, -48.17 74.21, -5.61 out-in-out SNCoio in-out ActLoopNT-in 2.698 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -61.27, 168.08 APE9-dihe-na -77.59, 175.7 APE8-dihe-in -63.31, 118.92 APE8-rot-in 314.45 APE67-dihe-in -61.09, -22.53 -42.79, -50.97 APE12-dist-in 9.9501 APE11-dist-out 7.4936 APE10-dist-out 9.8647 APE9-dist-in 4.1107 None None NEP125 XRAY 2.7 0.206 0.255 A 369.0 343.0 0 31 31 0 [[25, 313]] 1.0 4qp1 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP1B P28482 12 357 360.0 EMU:401 Type1 Inactive DFGin 6.6903 15.7386 BLAminus -124.13, -176.14 57.57, 85.87 -105.59, 31.14 285.08, 67.96 -70.32, -24.06 in-out in 9.5661 Saltbr-out 3.9932 HRD-in -75.52, -44.16 67.6, 8.01 out-in-out SNCoio in-out ActLoopNT-in 2.7216 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -127.44, 102.2 APE9-dihe-na 68.05, 148.06 APE8-dihe-in -61.45, 136.17 APE8-rot-in 303.04 APE67-dihe-in -60.44, -20.34 -48.19, -50.72 APE12-dist-in 8.9194 APE11-dist-in 8.2741 APE10-dist-out 8.2601 APE9-dist-in 3.1613 None None NEP125 XRAY 2.7 0.206 0.255 B 369.0 344.0 2 31 31 0 [[25, 313]] 1.0 4qp1 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP2A P28482 12 360 360.0 36R:401 Type1 Inactive DFGin 7.0169 16.3573 BLAminus -132.76, -176.99 60.37, 76.22 -97.44, 23.32 283.67, 70.96 -63.1, -20.06 in-in in 9.9583 Saltbr-in 3.2131 HRD-in -76.56, -48.46 78.73, -15.62 in-in-out SNCiio in-out ActLoopNT-in 2.6898 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -88.71, 155.85 APE9-dihe-na -97.01, 160.1 APE8-dihe-in -54.37, 118.09 APE8-rot-in 313.36 APE67-dihe-in -58.35, -23.39 -45.67, -50.34 APE12-dist-none 999.0 APE11-dist-out 7.8812 APE10-dist-out 9.9482 APE9-dist-in 4.4264 None None NEP125 XRAY 2.23 0.186 0.234 A 369.0 337.0 9 31 25 6 [[25, 313]] 1.0 4qp2 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP3A P28482 12 360 360.0 36Q:401 Type1 Inactive DFGin 6.8589 15.8504 BLAminus -127.22, -175.68 56.17, 83.19 -104.18, 33.87 282.73, 66.64 -69.96, -32.58 in-in in 9.4451 Saltbr-in 3.3006 HRD-in -82.76, -44.96 76.07, -9.05 in-in-out SNCiio in-out ActLoopNT-in 2.7052 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nioi APE10-dihe-na -121.34, 159.1 APE9-dihe-na -79.4, 177.88 APE8-dihe-in -61.83, 123.04 APE8-rot-in 305.81 APE67-dihe-in -62.86, -21.0 -53.45, -47.23 APE12-dist-none 999.0 APE11-dist-in 8.2622 APE10-dist-out 9.9697 APE9-dist-in 4.301 None None NEP125 XRAY 2.599 0.224 0.268 A 369.0 340.0 9 31 25 6 [[25, 313]] 1.0 4qp3 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP3B P28482 12 357 360.0 36Q:401 Type1 Inactive DFGin 6.793 15.7599 BLAminus -126.47, -174.48 52.27, 87.61 -103.66, 26.42 284.37, 73.41 -63.65, -24.28 in-in in 9.6052 Saltbr-in 3.1992 HRD-in -81.82, -47.44 72.19, -4.98 in-in-out SNCiio in-out ActLoopNT-in 2.6859 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na 63.14, -151.19 APE9-dihe-na -73.19, 165.34 APE8-dihe-in -60.84, 129.71 APE8-rot-in 299.14 APE67-dihe-in -62.09, -19.8 -45.81, -49.44 APE12-dist-in 9.7944 APE11-dist-in 8.512 APE10-dist-out 8.3522 APE9-dist-in 3.4733 None None NEP125 XRAY 2.599 0.224 0.268 B 369.0 332.0 11 31 28 3 [[25, 313]] 1.0 4qp3 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP4A P28482 13 357 360.0 36O:401 Type1 Inactive DFGin 6.8241 15.938 BLAminus -125.3, 167.13 64.24, 90.48 -108.14, 22.59 286.42, 75.22 -64.25, -26.15 in-out in 8.9178 Saltbr-out 6.0785 HRD-in -71.48, -47.45 75.24, -9.93 out-in-out SNCoio in-out ActLoopNT-in 2.9796 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -129.97, 154.52 APE9-dihe-na -62.24, -33.02 APE8-dihe-in -154.8, 145.42 APE8-rot-out 182.51 APE67-dihe-in -65.24, -7.26 -115.09, 10.29 APE12-dist-in 9.2228 APE11-dist-in 12.394 APE10-dist-out 9.1008 APE9-dist-out 11.038 None None None XRAY 2.2 0.189 0.235 A 369.0 337.0 8 31 23 8 [[25, 313]] 1.0 4qp4 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP4B P28482 12 357 360.0 36O:401 Type1 Inactive DFGin 6.9518 16.3408 BLAminus -131.86, 174.32 59.22, 89.07 -106.19, 23.73 288.41, 79.68 -67.52, -18.25 in-out in 9.2153 Saltbr-out 4.4894 HRD-in -76.21, -48.26 75.02, -6.33 out-in-out SNCoio in-out ActLoopNT-in 2.8132 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -122.9, 128.44 APE9-dihe-na -79.48, -89.06 APE8-dihe-in -75.04, 141.7 APE8-rot-in 317.37 APE67-dihe-in -69.0, -20.44 -124.09, -5.27 APE12-dist-in 9.1797 APE11-dist-in 12.4613 APE10-dist-out 11.2141 APE9-dist-out 10.244 None None None XRAY 2.2 0.189 0.235 B 369.0 335.0 11 31 20 11 [[25, 313]] 1.0 4qp4 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP6A P28482 12 360 360.0 36N:401 Type1 Inactive DFGin 6.8649 16.0487 BLAminus -134.19, 177.24 61.24, 85.87 -106.12, 27.42 286.39, 74.31 -64.08, -29.18 in-in in 9.7186 Saltbr-in 3.1724 HRD-in -73.59, -43.93 70.49, -12.41 in-in-out SNCiio in-out ActLoopNT-in 2.6757 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -93.66, 171.23 APE9-dihe-na -81.86, -178.38 APE8-dihe-in -66.96, 124.64 APE8-rot-in 304.43 APE67-dihe-in -65.66, -28.46 -50.73, -45.49 APE12-dist-none 999.0 APE11-dist-out 7.8432 APE10-dist-out 9.8747 APE9-dist-in 4.1913 None None NEP125 XRAY 3.1 0.215 0.251 A 369.0 340.0 9 31 25 6 [[25, 313]] 1.0 4qp6 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP6B P28482 12 357 360.0 36N:401 Type1 Inactive DFGin 6.7833 15.6243 BLAminus -135.41, -176.58 58.97, 85.85 -108.91, 30.4 287.99, 68.55 -72.19, -15.06 in-in in 9.6133 Saltbr-in 3.4142 HRD-in -81.72, -40.85 62.99, 11.61 in-in-out SNCiio in-out ActLoopNT-in 2.729 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -112.85, 150.4 APE9-dihe-na -66.19, 155.78 APE8-dihe-in -60.29, 123.23 APE8-rot-in 306.84 APE67-dihe-in -59.17, -27.19 -47.63, -50.44 APE12-dist-in 9.0613 APE11-dist-out 6.8478 APE10-dist-out 9.6916 APE9-dist-in 3.6394 None None NEP125 XRAY 3.1 0.215 0.251 B 369.0 335.0 11 31 28 3 [[25, 313]] 1.0 4qp6 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP7A P28482 13 357 360.0 363:401 Type1 Inactive DFGin 6.8497 15.7484 BLAminus -132.24, 176.87 62.32, 84.56 -106.17, 23.49 288.44, 72.17 -65.38, -26.87 in-in in 8.7515 Saltbr-in 3.3931 HRD-in -78.16, -47.13 71.74, -6.4 in-in-out SNCiio in-out ActLoopNT-in 2.8517 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -125.07, 152.43 APE9-dihe-na -64.16, -36.92 APE8-dihe-in -151.45, 144.61 APE8-rot-out 177.7 APE67-dihe-in -68.24, -8.08 -110.93, 12.21 APE12-dist-in 8.8566 APE11-dist-in 12.196 APE10-dist-out 9.2472 APE9-dist-out 10.8468 None None None XRAY 2.249 0.208 0.243 A 369.0 337.0 8 31 23 8 [[25, 313]] 1.0 4qp7 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP7B P28482 12 357 360.0 363:401 Type1 Inactive DFGin 7.1055 16.6106 BLAminus -135.43, 179.06 61.46, 85.59 -106.29, 24.23 287.16, 78.5 -67.15, -18.05 in-out in 9.8132 Saltbr-out 4.1382 HRD-in -76.72, -48.85 72.61, -2.86 out-in-out SNCoio in-out ActLoopNT-in 2.6685 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -114.32, 148.28 APE9-dihe-na -105.7, -8.19 APE8-dihe-in -170.3, 125.09 APE8-rot-in 288.27 APE67-dihe-in -58.36, -23.63 -104.22, -4.05 APE12-dist-in 9.4012 APE11-dist-in 12.4348 APE10-dist-out 10.8813 APE9-dist-out 10.2343 None None None XRAY 2.249 0.208 0.243 B 369.0 335.0 11 31 20 11 [[25, 313]] 1.0 4qp7 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP8A P28482 12 357 360.0 362:401 Type1 Inactive DFGin 7.1206 16.0234 BLAminus -138.97, 178.67 58.83, 81.69 -100.67, 28.37 284.73, 74.19 -64.65, -23.89 in-in in 9.1643 Saltbr-in 2.4899 HRD-in -76.49, -45.63 73.25, -7.2 in-in-out SNCiio in-out ActLoopNT-in 2.6578 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -115.06, 140.25 APE9-dihe-na -81.99, -90.41 APE8-dihe-in -85.54, 134.34 APE8-rot-in 298.33 APE67-dihe-in -61.64, -19.92 -107.69, -3.1 APE12-dist-in 9.7117 APE11-dist-in 12.1893 APE10-dist-out 11.013 APE9-dist-out 10.0751 None None None XRAY 2.446 0.206 0.249 A 369.0 335.0 11 31 20 11 [[25, 313]] 1.0 4qp8 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP8B P28482 13 357 360.0 362:401 Type1 Inactive DFGin 6.976 15.4619 BLAminus -132.6, -178.43 57.44, 85.0 -105.8, 25.19 285.22, 65.23 -60.86, -34.2 in-in in 8.8253 Saltbr-in 3.0801 HRD-in -81.03, -47.24 74.23, -7.22 in-in-out SNCiio in-out ActLoopNT-in 2.841 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -127.99, 150.46 APE9-dihe-na -61.94, -34.3 APE8-dihe-in -151.1, 145.37 APE8-rot-out 182.62 APE67-dihe-in -74.4, -5.5 -115.62, 16.65 APE12-dist-in 9.3382 APE11-dist-in 12.306 APE10-dist-out 9.2112 APE9-dist-out 10.8388 None None None XRAY 2.446 0.206 0.249 B 369.0 337.0 8 31 23 8 [[25, 313]] 1.0 4qp8 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QP9A P28482 13 357 360.0 35X:401 Type1 Inactive DFGin 6.9376 15.3413 BLAminus -130.0, -173.82 68.16, 72.94 -105.1, 24.85 282.89, 75.71 -66.76, -30.66 in-in in 9.3786 Saltbr-in 2.5118 HRD-in -80.31, -47.56 78.27, -7.94 in-in-out SNCiio in-out ActLoopNT-in 2.699 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -135.53, 155.6 APE9-dihe-na -68.22, -35.06 APE8-dihe-in -149.12, 139.63 APE8-rot-out 179.85 APE67-dihe-in -66.79, -15.72 -108.34, 3.59 APE12-dist-in 9.614 APE11-dist-in 13.1378 APE10-dist-out 9.8164 APE9-dist-out 11.7397 None None None XRAY 2.001 0.186 0.227 A 369.0 335.0 8 31 23 8 [[25, 313]] 1.0 4qp9 CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QPAA P28482 12 357 360.0 35W:60401 Type1 Inactive DFGin 6.6307 15.6681 BLAminus -136.5, -177.35 57.93, 81.68 -102.89, 29.52 286.81, 65.92 -68.51, -24.46 in-out in 9.4927 Saltbr-out 3.8625 HRD-in -77.16, -44.3 70.0, -5.49 out-in-out SNCoio in-out ActLoopNT-in 2.6862 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -133.82, -177.08 APE9-dihe-na -115.74, 137.26 APE8-dihe-in -54.82, 121.13 APE8-rot-in 306.72 APE67-dihe-in -60.3, -21.81 -45.58, -51.1 APE12-dist-in 10.2377 APE11-dist-in 9.4922 APE10-dist-out 8.8648 APE9-dist-in 3.8432 None None NEP125 XRAY 2.85 0.214 0.253 A 369.0 332.0 11 31 28 3 [[25, 313]] 1.0 4qpa CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QPAB P28482 12 360 360.0 35W:60401 Type1 Inactive DFGin 6.8708 16.2178 BLAminus -133.06, 176.84 64.38, 82.12 -104.1, 27.34 284.96, 71.65 -64.94, -31.45 out-in out 10.0662 Saltbr-in 3.3168 HRD-in -76.47, -42.35 70.97, -15.95 in-in-out SNCiio in-out ActLoopNT-in 2.71 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -93.45, -162.2 APE9-dihe-na -84.91, -167.23 APE8-dihe-in -75.25, 118.31 APE8-rot-in 309.12 APE67-dihe-in -62.58, -28.37 -42.27, -50.62 APE12-dist-in 11.0287 APE11-dist-in 8.7807 APE10-dist-out 8.9155 APE9-dist-in 4.3175 None None NEP125 XRAY 2.85 0.214 0.253 B 369.0 346.0 2 31 29 2 [[25, 313]] 1.0 4qpa CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4ZZMA P28482 11 355 360.0 CQ6:1357 Type1 Inactive DFGin 7.0304 16.3552 BLAminus -126.63, -175.69 56.15, 85.43 -102.35, 20.51 285.78, 80.49 -63.28, -29.01 in-out in 9.8603 Saltbr-out 4.5679 HRD-in -72.39, -53.13 71.33, 3.98 out-in-out SNCoio in-out ActLoopNT-in 2.8685 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -110.95, 138.07 APE9-dihe-na 65.0, -177.02 APE8-dihe-in -89.16, 134.03 APE8-rot-in 293.15 APE67-dihe-in -60.55, -17.17 -32.84, -60.53 APE12-dist-in 13.2012 APE11-dist-in 11.2942 APE10-dist-out 8.9595 APE9-dist-in 3.1317 None None CME161 XRAY 1.89 0.21 0.254 A 350.0 345.0 0 31 31 0 [[25, 313]] 1.0 4zzm CMGC_MAPK1_HUMAN CMGC 1.2e-85 293.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4ZZNA P28482 11 355 360.0 CQ8:61355 Type1 Inactive DFGin 6.7305 16.385 BLAminus -125.62, 167.09 59.43, 95.37 -102.42, 18.52 285.84, 80.13 -61.06, -26.76 in-in in 9.3407 Saltbr-in 2.8014 HRD-in -67.38, -51.21 72.41, 6.03 in-in-out SNCiio in-out ActLoopNT-in 2.8141 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -89.29, -45.49 APE9-dihe-na -50.96, 152.72 APE8-dihe-in -55.84, 123.26 APE8-rot-in 314.25 APE67-dihe-in -59.18, -22.99 -48.37, -54.07 APE12-dist-out 14.4485 APE11-dist-in 11.2871 APE10-dist-in 7.0346 APE9-dist-in 4.087 None None CME161 XRAY 1.33 0.175 0.202 A 350.0 339.0 0 31 31 0 [[25, 313]] 1.0 4zzn CMGC_MAPK1_HUMAN CMGC 1.2e-85 293.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4ZZOA P28482 11 355 360.0 CQ3:1357 Type1 Inactive DFGin 6.887 16.2189 BLAminus -131.27, 174.96 60.69, 93.91 -105.67, 18.33 284.84, 78.56 -63.6, -22.53 in-in in 9.1104 Saltbr-in 2.6757 HRD-in -66.92, -50.1 73.58, 2.48 in-in-out SNCiio in-out ActLoopNT-in 2.8175 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -107.77, 141.44 APE9-dihe-na 63.91, 177.13 APE8-dihe-in -84.81, 136.22 APE8-rot-in 291.46 APE67-dihe-in -63.19, -21.52 -37.39, -54.7 APE12-dist-in 13.4742 APE11-dist-in 11.6356 APE10-dist-out 9.0137 APE9-dist-in 3.1946 None None CME161 XRAY 1.63 0.191 0.237 A 350.0 340.0 0 31 31 0 [[25, 313]] 1.0 4zzo CMGC_MAPK1_HUMAN CMGC 1.2e-85 293.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 2OJGA P28482 19 357 360.0 19A:60360 Type1 Inactive DFGin 6.779 15.7199 BLAminus -127.46, 179.27 64.17, 86.16 -104.35, 28.83 283.56, 69.28 -67.52, -27.97 in-in in 9.5989 Saltbr-in 2.6042 HRD-in -75.69, -53.61 79.84, -2.74 in-in-out SNCiio in-out ActLoopNT-in 2.6951 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.83, -40.68 APE9-dihe-na -55.36, 156.37 APE8-dihe-in -56.12, 134.31 APE8-rot-in 307.38 APE67-dihe-in -61.84, -15.71 -62.4, -48.63 APE12-dist-out 14.7058 APE11-dist-in 11.2638 APE10-dist-in 7.3646 APE9-dist-in 4.3678 None None None XRAY 2.0 0.233 0.26 A 380.0 337.0 0 31 31 0 [[25, 313]] 1.0 2ojg CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 2OJIA P28482 15 358 360.0 33A:60360 Type1 Inactive DFGin 6.7854 16.3983 BLAminus -132.53, 175.62 62.73, 87.52 -104.73, 37.95 284.25, 59.44 -73.68, -20.82 out-in out 10.1012 Saltbr-in 3.1148 HRD-in -72.86, -54.76 76.49, 2.85 in-in-out SNCiio in-out ActLoopNT-in 2.8555 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.26, -26.54 APE9-dihe-na -67.43, 166.5 APE8-dihe-in -61.43, 135.98 APE8-rot-in 299.82 APE67-dihe-in -66.79, -11.81 -72.57, -38.73 APE12-dist-out 14.6525 APE11-dist-in 11.2062 APE10-dist-in 7.3794 APE9-dist-in 4.3911 None None None XRAY 2.6 0.239 0.267 A 380.0 344.0 0 31 31 0 [[25, 313]] 1.0 2oji CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 2OJJA P28482 15 358 360.0 82A:60360 Type1 Inactive DFGin 6.9278 15.7087 BLAminus -134.63, 171.22 66.3, 85.66 -103.17, 35.01 286.71, 65.45 -71.35, -20.96 in-in in 9.5705 Saltbr-in 2.5872 HRD-in -72.18, -44.82 72.99, -2.41 in-in-out SNCiio in-out ActLoopNT-in 2.7625 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -117.66, -34.13 APE9-dihe-na -60.97, 166.57 APE8-dihe-in -69.05, 134.04 APE8-rot-in 303.47 APE67-dihe-in -59.58, -20.53 -59.77, -50.51 APE12-dist-out 14.4453 APE11-dist-in 11.1936 APE10-dist-in 7.1623 APE9-dist-in 4.116 None None None XRAY 2.4 0.215 0.268 A 380.0 344.0 0 31 31 0 [[25, 313]] 1.0 2ojj CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 9LNRA P28482 9 358 360.0 A1EKR:401 Type1 Inactive DFGin 6.8939 14.8353 BLAminus -132.98, -174.48 54.93, 86.46 -100.06, 23.76 285.97, 66.46 -61.1, -34.13 in-in in 9.0292 Saltbr-in 2.5011 HRD-in -74.57, -52.5 79.29, -5.96 in-in-out SNCiio in-out ActLoopNT-in 2.7074 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -155.64 APE8-rot-out 57.16 APE67-dihe-in -69.2, -14.2 -106.5, 12.61 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.1 0.213 0.277 A 380.0 333.0 17 31 16 15 [[25, 313]] 1.0 9lnr CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5NGUA P28482 11 355 360.0 8X2:403 Type1 Inactive DFGin 6.8244 15.4125 BLAminus -131.8, 173.94 54.59, 63.73 -75.37, 12.55 291.92, 86.34 -57.76, -29.82 in-in in 9.3443 Saltbr-in 2.5044 HRD-in -69.49, -51.37 67.92, 17.66 in-in-out SNCiio in-out ActLoopNT-in 2.7727 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -117.12, -31.72 APE9-dihe-na -50.59, 143.23 APE8-dihe-in -52.47, 127.91 APE8-rot-in 314.94 APE67-dihe-in -84.77, -26.48 -48.59, -26.11 APE12-dist-out 14.4197 APE11-dist-in 11.354 APE10-dist-in 7.6339 APE9-dist-in 4.0226 None None CME161 XRAY 2.74 0.266 0.262 A 381.0 340.0 0 31 31 0 [[25, 313]] 1.0 5ngu CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5NHFA P28482 12 355 360.0 8X5:402 Type1 Inactive DFGin 6.9779 15.7383 BLAminus -131.22, -177.26 60.47, 71.66 -95.07, 17.48 291.88, 68.57 -59.32, -37.52 in-out in 9.8227 Saltbr-out 4.1383 HRD-in -69.08, -56.17 78.63, -4.25 out-in-out SNCoio in-out ActLoopNT-in 2.6998 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -113.63, -36.25 APE9-dihe-na -59.51, 153.91 APE8-dihe-in -53.09, 125.53 APE8-rot-in 307.89 APE67-dihe-in -66.28, -15.97 -57.32, -40.32 APE12-dist-out 14.2616 APE11-dist-in 11.1646 APE10-dist-in 7.0321 APE9-dist-in 4.1558 None None CME161 XRAY 2.14 0.248 0.259 A 381.0 340.0 0 31 31 0 [[25, 313]] 1.0 5nhf CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5NHHA P28482 11 358 360.0 8XH:404 Type1 Inactive DFGin 6.9774 14.8199 BLAminus -123.6, -173.61 56.59, 82.5 -98.03, 21.32 285.02, 79.79 -59.4, -24.9 in-in in 9.2106 Saltbr-in 2.7434 HRD-in -74.19, -51.04 72.31, 4.45 in-in-out SNCiio in-out ActLoopNT-in 2.7951 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -94.16, -52.11 APE9-dihe-na -51.37, 157.59 APE8-dihe-in -65.96, 124.8 APE8-rot-in 313.27 APE67-dihe-in -57.65, -21.58 -40.05, -64.42 APE12-dist-out 14.4064 APE11-dist-in 11.1634 APE10-dist-in 6.8103 APE9-dist-in 4.039 None None None XRAY 1.94 0.183 0.22 A 381.0 348.0 0 31 31 0 [[25, 313]] 1.0 5nhh CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5NHJA P28482 11 355 360.0 8XE:403 Type1 Inactive DFGin 7.0703 14.9245 BLAminus -129.81, -179.77 60.64, 76.52 -95.64, 20.89 284.82, 79.91 -59.37, -34.53 in-in in 9.2753 Saltbr-in 2.5321 HRD-in -67.69, -55.32 71.57, 12.88 in-in-out SNCiio in-out ActLoopNT-in 2.7635 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -90.43, -16.06 APE9-dihe-na -73.33, 160.47 APE8-dihe-in -60.61, 133.87 APE8-rot-in 319.8 APE67-dihe-in -65.92, -16.91 -61.1, -44.69 APE12-dist-out 14.3741 APE11-dist-in 11.1093 APE10-dist-in 7.1667 APE9-dist-in 4.3832 None None None XRAY 2.12 0.202 0.207 A 381.0 345.0 0 31 31 0 [[25, 313]] 1.0 5nhj CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5NHLA P28482 11 355 360.0 8XB:402 Type1 Inactive DFGin 6.8158 15.2822 BLAminus -139.26, -173.51 58.97, 71.02 -94.26, 20.48 284.18, 78.38 -54.1, -36.53 in-in in 9.6258 Saltbr-in 3.1614 HRD-in -64.32, -47.55 73.98, -3.15 in-in-out SNCiio in-out ActLoopNT-in 2.8784 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.51, -36.44 APE9-dihe-na -58.94, 156.87 APE8-dihe-in -57.88, 132.4 APE8-rot-in 306.9 APE67-dihe-in -55.59, -21.11 -57.75, -53.28 APE12-dist-out 14.1519 APE11-dist-in 10.9351 APE10-dist-in 6.8636 APE9-dist-in 4.3969 None None None XRAY 2.07 0.211 0.237 A 381.0 345.0 0 31 31 0 [[25, 313]] 1.0 5nhl CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5NHOA P28482 11 355 360.0 8XN:402 Type1 Inactive DFGin 6.7748 14.9302 BLAminus -128.12, -172.81 57.57, 69.48 -93.21, 16.81 282.74, 78.43 -59.67, -38.3 in-in in 9.3082 Saltbr-in 2.4319 HRD-in -70.35, -53.92 79.23, -4.46 in-in-out SNCiio in-out ActLoopNT-in 2.9382 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -77.13, -52.3 APE9-dihe-na -46.62, 149.13 APE8-dihe-in -50.41, 119.77 APE8-rot-in 304.89 APE67-dihe-in -57.6, -18.79 -46.37, -52.99 APE12-dist-out 14.5068 APE11-dist-in 11.0345 APE10-dist-in 7.1188 APE9-dist-in 4.4481 None None None XRAY 2.24 0.201 0.231 A 381.0 343.0 0 31 31 0 [[25, 313]] 1.0 5nho CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5NHPA P28482 11 355 360.0 8XK:403 Type1 Inactive DFGin 6.7358 15.287 BLAminus -133.41, 177.47 61.57, 77.45 -96.25, 22.52 284.35, 75.89 -59.57, -36.21 in-in in 9.4483 Saltbr-in 3.0231 HRD-in -65.9, -48.64 69.88, 3.81 in-in-out SNCiio in-out ActLoopNT-in 2.7445 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.85, -37.07 APE9-dihe-na -65.74, 155.72 APE8-dihe-in -47.43, 115.1 APE8-rot-in 316.51 APE67-dihe-in -59.18, -15.78 -43.52, -52.87 APE12-dist-out 14.5075 APE11-dist-in 11.1324 APE10-dist-in 7.1095 APE9-dist-in 4.4778 None None None XRAY 1.99 0.199 0.221 A 381.0 338.0 0 31 31 0 [[25, 313]] 1.0 5nhp CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5NHVA P28482 11 355 360.0 8QB:402 Type1 Inactive DFGin 6.9487 15.3641 BLAminus -123.53, 177.96 58.53, 89.42 -103.15, 22.56 288.99, 74.77 -58.64, -38.74 in-in in 9.121 Saltbr-in 2.7836 HRD-in -72.87, -48.92 68.99, 2.01 in-in-out SNCiio in-out ActLoopNT-in 2.8764 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -87.07, -47.14 APE9-dihe-na -52.95, 153.81 APE8-dihe-in -61.02, 123.38 APE8-rot-in 307.95 APE67-dihe-in -56.45, -21.77 -45.48, -58.17 APE12-dist-out 14.3987 APE11-dist-in 11.3086 APE10-dist-in 6.9029 APE9-dist-in 4.0801 None None None XRAY 2.0 0.186 0.228 A 381.0 345.0 0 31 31 0 [[25, 313]] 1.0 5nhv CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6SLGA P28482 18 356 360.0 LHZ:401 Type1 Inactive DFGin 6.8771 15.8272 BLAminus -132.14, -179.5 65.09, 83.25 -102.36, 23.01 284.81, 73.87 -64.88, -22.82 in-in in 9.9163 Saltbr-in 2.7035 HRD-in -74.6, -50.76 72.67, 6.01 in-in-out SNCiio in-out ActLoopNT-in 2.8059 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.29, -34.93 APE9-dihe-na -64.83, 158.43 APE8-dihe-in -48.5, 123.79 APE8-rot-in 311.17 APE67-dihe-in -63.81, -16.49 -52.51, -50.2 APE12-dist-out 14.3759 APE11-dist-in 11.1095 APE10-dist-in 7.2847 APE9-dist-in 4.3841 None None None XRAY 1.33 0.207 0.228 A 381.0 332.0 0 31 31 0 [[25, 313]] 1.0 6slg CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5WP1A P28482 15 357 360.0 B7S:401,BEZ:403 Type1,Allosteric Inactive DFGin 6.8478 16.8208 BLAminus -131.08, 174.79 68.08, 80.16 -96.05, 24.08 289.54, 79.55 -65.36, -26.41 out-out out 10.2828 Saltbr-out 6.6659 HRD-in -74.08, -53.37 76.14, 3.14 out-in-out SNCoio in-out ActLoopNT-in 2.8044 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.04, -37.91 APE9-dihe-na -67.19, 159.66 APE8-dihe-in -53.56, 128.07 APE8-rot-in 309.0 APE67-dihe-in -66.9, -15.26 -56.35, -46.18 APE12-dist-out 14.1878 APE11-dist-in 10.9008 APE10-dist-in 7.0449 APE9-dist-in 4.4209 None None CME127,CME161,CME166 XRAY 1.4 0.142 0.18 A 357.0 343.0 0 31 31 0 [[25, 313]] 1.0 5wp1 CMGC_MAPK1_HUMAN CMGC 8.9e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6Q7TA P28482 11 356 360.0 HOW:402,HOW:403 Type1,Allosteric Inactive DFGin 6.7308 16.4827 BLAminus -134.88, 178.16 63.34, 76.93 -96.51, 20.6 283.36, 78.59 -63.48, -26.46 in-out in 9.7295 Saltbr-out 5.6666 HRD-in -72.05, -52.36 73.88, 5.86 out-in-out SNCoio in-out ActLoopNT-in 2.8281 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -92.01, -37.19 APE9-dihe-na -68.64, 160.64 APE8-dihe-in -64.39, 130.65 APE8-rot-in 311.37 APE67-dihe-in -64.26, -15.1 -59.16, -48.05 APE12-dist-out 14.1314 APE11-dist-in 10.8768 APE10-dist-in 6.6787 APE9-dist-in 4.0846 None None CME161 XRAY 1.6 0.183 0.227 A 368.0 340.0 0 31 31 0 [[25, 313]] 1.0 6q7t CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6QAGA P28482 11 357 360.0 HUH:404,HUH:405 Type1,Allosteric Inactive DFGin 6.6737 16.3283 BLAminus -131.07, 179.69 59.56, 79.71 -94.59, 23.02 291.33, 80.77 -60.94, -31.24 out-out out 10.1879 Saltbr-out 6.317 HRD-in -68.77, -49.91 69.72, -0.83 out-in-out SNCoio in-out ActLoopNT-in 2.6962 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -85.9, -34.97 APE9-dihe-na -66.74, 159.57 APE8-dihe-in -60.99, 132.48 APE8-rot-in 309.19 APE67-dihe-in -70.55, -17.76 -62.43, -41.0 APE12-dist-out 14.314 APE11-dist-in 10.9391 APE10-dist-in 7.144 APE9-dist-in 4.5323 None None CME161 XRAY 2.07 0.187 0.235 A 368.0 340.0 0 31 31 0 [[25, 313]] 1.0 6qag CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AOAA P28482 11 356 360.0 N83:406,OZU:407 Type1,Allosteric Inactive DFGin 6.7931 16.527 BLAminus -135.38, -176.79 59.99, 79.64 -96.04, 23.18 287.21, 76.82 -63.39, -28.33 out-in out 10.2665 Saltbr-in 2.8684 HRD-in -70.35, -52.0 72.83, 3.26 in-in-out SNCiio in-out ActLoopNT-in 2.7969 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.11, -37.31 APE9-dihe-na -66.5, 160.64 APE8-dihe-in -61.93, 128.37 APE8-rot-in 309.77 APE67-dihe-in -60.49, -16.92 -57.79, -48.55 APE12-dist-out 14.4472 APE11-dist-in 11.0079 APE10-dist-in 6.9063 APE9-dist-in 4.2056 None None CME161 XRAY 1.62 0.182 0.232 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 8aoa CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AODA P28482 11 356 360.0 NY0:404,NYI:405 Type1,Allosteric Inactive DFGin 6.8231 16.0357 BLAminus -131.17, -179.47 57.68, 82.31 -96.08, 20.12 286.18, 76.41 -64.6, -20.71 in-in in 9.9784 Saltbr-in 3.1285 HRD-in -70.94, -51.02 75.95, 2.66 in-in-out SNCiio in-out ActLoopNT-in 2.8057 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.18, -34.01 APE9-dihe-na -67.78, 158.19 APE8-dihe-in -55.04, 129.71 APE8-rot-in 310.11 APE67-dihe-in -63.45, -16.67 -58.94, -47.88 APE12-dist-out 14.4183 APE11-dist-in 11.0901 APE10-dist-in 6.9955 APE9-dist-in 4.2756 None None CME161 XRAY 1.62 0.191 0.227 A 368.0 335.0 4 31 31 0 [[25, 313]] 1.0 8aod CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AOHA P28482 11 356 360.0 N96:405,N96:406 Type1,Allosteric Inactive DFGin 6.8299 16.5947 BLAminus -132.83, 177.1 62.85, 85.04 -99.02, 23.99 285.97, 81.42 -64.74, -29.87 out-in out 10.2677 Saltbr-in 3.4631 HRD-in -72.11, -50.02 74.87, 0.95 in-in-out SNCiio in-out ActLoopNT-in 2.8165 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -90.28, -37.21 APE9-dihe-na -70.91, 159.97 APE8-dihe-in -57.17, 128.99 APE8-rot-in 305.99 APE67-dihe-in -64.24, -15.82 -57.85, -48.55 APE12-dist-out 14.2058 APE11-dist-in 10.9951 APE10-dist-in 6.7768 APE9-dist-in 4.3046 None None CME161 XRAY 1.6 0.172 0.214 A 368.0 334.0 4 31 31 0 [[25, 313]] 1.0 8aoh CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 8AOIA P28482 11 356 360.0 NX0:405,NX0:406 Type1,Allosteric Inactive DFGin 6.8878 16.3934 BLAminus -136.78, 177.1 63.08, 84.65 -99.16, 21.81 286.0, 77.79 -61.3, -28.58 out-in out 10.3656 Saltbr-in 2.8069 HRD-in -73.8, -50.98 78.41, -1.24 in-in-out SNCiio in-out ActLoopNT-in 2.8176 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -92.32, -37.26 APE9-dihe-na -67.19, 156.47 APE8-dihe-in -52.14, 125.91 APE8-rot-in 308.25 APE67-dihe-in -65.16, -15.87 -56.81, -46.51 APE12-dist-out 14.295 APE11-dist-in 10.9812 APE10-dist-in 6.8569 APE9-dist-in 4.3055 None None CME161 XRAY 1.602 0.164 0.202 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 8aoi CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7XC1A P28482 10 360 360.0 5ID:401,B8Z:405 Type1,Allosteric Inactive DFGin 6.7078 15.976 BLAminus -137.71, -179.56 58.01, 78.42 -93.4, 30.18 285.99, 69.28 -65.81, -34.24 in-in in 9.5275 Saltbr-in 2.9997 HRD-in -74.95, -51.9 73.0, -2.02 in-in-out SNCiio in-out ActLoopNT-in 2.7443 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -122.62, 101.42 APE9-dihe-na 74.74, 135.42 APE8-dihe-in -55.35, 136.96 APE8-rot-in 306.98 APE67-dihe-in -57.04, -22.83 -48.83, -53.13 APE12-dist-in 8.7119 APE11-dist-out 7.512 APE10-dist-in 7.787 APE9-dist-in 3.0162 None None NEP125 XRAY 2.09 0.232 0.271 A 368.0 351.0 0 31 31 0 [[25, 313]] 1.0 7xc1 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7X4UA P28482 10 359 360.0 5ID:401,8DK:402,BTB:404 Type1,Allosteric,Allosteric Inactive DFGin 6.9264 15.7569 BLAminus -130.94, 179.99 65.43, 75.46 -94.7, 29.02 282.13, 69.46 -67.73, -25.68 in-out in 9.857 Saltbr-out 4.0629 HRD-in -76.85, -49.01 74.24, 2.54 out-in-in SNCoii in-in ActLoopNT-in 2.6947 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -104.34, -27.33 APE9-dihe-na -70.01, 158.49 APE8-dihe-in -59.37, 130.23 APE8-rot-in 310.67 APE67-dihe-in -64.33, -17.62 -55.67, -49.5 APE12-dist-in 13.752 APE11-dist-in 10.9435 APE10-dist-in 7.171 APE9-dist-in 4.5619 None None None XRAY 1.98 0.199 0.235 A 368.0 350.0 0 31 31 0 [[25, 313]] 1.0 7x4u CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4QTAA P28482 10 358 360.0 38Z:411 Type1.5_Front Inactive DFGin 6.9014 16.419 BLAminus -127.54, 173.07 71.53, 87.6 -104.51, 22.85 289.22, 73.36 -66.57, -25.44 in-in in 9.6271 Saltbr-in 2.6475 HRD-in -72.05, -50.52 77.72, -5.81 in-in-out SNCiio in-out ActLoopNT-in 2.7868 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 141.19 APE8-rot-out 186.7 APE67-dihe-in -78.23, -10.32 -106.34, 7.24 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.45 0.16 0.191 A 361.0 335.0 14 31 17 14 [[25, 313]] 1.0 4qta CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G9DA P28482 8 357 360.0 ER8:406 Type1.5_Front Inactive DFGin 6.8322 16.4174 BLAminus -130.82, 177.58 62.78, 85.24 -103.76, 20.35 283.71, 79.73 -63.11, -28.56 in-in in 9.9441 Saltbr-in 2.6335 HRD-in -73.65, -52.91 75.39, 8.67 in-in-out SNCiio in-out ActLoopNT-in 2.8528 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.6, -41.14 APE9-dihe-na -67.27, 166.02 APE8-dihe-in -67.59, 131.6 APE8-rot-in 309.39 APE67-dihe-in -67.26, -16.88 -58.97, -46.53 APE12-dist-out 14.4705 APE11-dist-in 11.1692 APE10-dist-in 7.0045 APE9-dist-in 4.1624 None None CME161 XRAY 1.8 0.169 0.223 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 6g9d CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G9HA P28482 11 357 360.0 ERW:405 Type1.5_Front Inactive DFGin 6.8629 16.1934 BLAminus -129.54, 176.24 67.51, 84.59 -100.67, 23.24 285.23, 76.32 -64.98, -24.84 out-in out 10.1259 Saltbr-in 2.6489 HRD-in -73.48, -50.99 74.79, 0.78 in-in-out SNCiio in-out ActLoopNT-in 2.8679 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.85, -36.75 APE9-dihe-na -71.44, 161.71 APE8-dihe-in -53.41, 125.25 APE8-rot-in 311.99 APE67-dihe-in -63.79, -17.26 -57.75, -47.59 APE12-dist-out 14.5021 APE11-dist-in 11.1983 APE10-dist-in 7.0379 APE9-dist-in 4.3282 None None CME161 XRAY 1.73 0.164 0.213 A 368.0 344.0 0 31 31 0 [[25, 313]] 1.0 6g9h CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G9JA P28482 8 357 360.0 ERK:403 Type1.5_Front Inactive DFGin 6.8519 16.4502 BLAminus -129.62, 174.38 66.65, 81.52 -99.73, 19.69 286.36, 76.45 -66.94, -21.09 in-in in 9.657 Saltbr-in 2.7199 HRD-in -69.57, -51.16 71.71, 3.51 in-in-out SNCiio in-out ActLoopNT-in 2.7648 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -94.41, -41.74 APE9-dihe-na -65.68, 165.5 APE8-dihe-in -68.67, 127.92 APE8-rot-in 310.31 APE67-dihe-in -68.75, -18.58 -53.05, -47.45 APE12-dist-out 14.7089 APE11-dist-in 11.2293 APE10-dist-in 7.1623 APE9-dist-in 4.3572 None None CME127,CME161,CME166 XRAY 1.98 0.162 0.212 A 368.0 350.0 0 31 31 0 [[25, 313]] 1.0 6g9j CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G9KA P28482 11 357 360.0 ESK:404 Type1.5_Front Inactive DFGin 6.8688 16.5006 BLAminus -127.44, 173.71 64.58, 89.87 -103.62, 17.25 282.92, 76.11 -73.44, -14.72 in-in in 9.7377 Saltbr-in 2.645 HRD-in -66.45, -52.24 73.55, 2.38 in-in-out SNCiio in-out ActLoopNT-in 2.8371 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.11, -41.06 APE9-dihe-na -64.16, 170.62 APE8-dihe-in -77.68, 128.75 APE8-rot-in 308.66 APE67-dihe-in -63.28, -19.27 -55.77, -50.47 APE12-dist-out 14.9684 APE11-dist-in 11.4607 APE10-dist-in 7.3076 APE9-dist-in 4.294 None None CME127,CME161 XRAY 1.94 0.164 0.223 A 368.0 345.0 0 31 31 0 [[25, 313]] 1.0 6g9k CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6G9NA P28482 11 357 360.0 ESN:407 Type1.5_Front Inactive DFGin 7.1331 16.5261 BLAminus -124.73, 175.13 63.57, 85.94 -99.62, 16.39 282.24, 77.66 -74.35, -19.57 out-in out 10.1647 Saltbr-in 2.7503 HRD-in -70.0, -50.46 74.7, 7.06 in-in-out SNCiio in-out ActLoopNT-in 2.8284 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -65.54, 147.38 APE9-dihe-na 67.51, -176.26 APE8-dihe-in -97.0, 144.29 APE8-rot-in 289.97 APE67-dihe-in -64.18, -20.4 -49.42, -51.94 APE12-dist-in 13.6331 APE11-dist-in 11.7222 APE10-dist-out 9.0098 APE9-dist-in 3.2103 None None CME161 XRAY 1.76 0.168 0.218 A 368.0 345.0 0 31 31 0 [[25, 313]] 1.0 6g9n CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6GDMA P28482 8 356 360.0 F3Z:404 Type1.5_Front Inactive DFGin 6.8409 16.5265 BLAminus -126.95, 171.54 65.54, 87.24 -101.62, 18.17 285.3, 73.79 -62.71, -23.55 in-in in 9.6417 Saltbr-in 2.6906 HRD-in -73.55, -51.55 74.53, 5.94 in-in-out SNCiio in-out ActLoopNT-in 2.769 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.91, -41.51 APE9-dihe-na -60.95, 166.12 APE8-dihe-in -74.95, 131.2 APE8-rot-in 307.5 APE67-dihe-in -60.9, -19.09 -57.69, -50.8 APE12-dist-out 14.6522 APE11-dist-in 11.2741 APE10-dist-in 7.2129 APE9-dist-in 4.1072 None None CME65,CME161,CME166,CME254 XRAY 1.91 0.185 0.243 A 368.0 345.0 0 31 31 0 [[25, 313]] 1.0 6gdm CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6GE0A P28482 11 357 360.0 EVQ:406 Type1.5_Front Inactive DFGin 6.8071 16.4086 BLAminus -125.01, 178.42 65.88, 86.44 -104.81, 21.96 285.23, 73.29 -68.51, -20.31 in-in in 9.8525 Saltbr-in 2.6163 HRD-in -69.56, -50.3 73.32, 2.78 in-in-out SNCiio in-out ActLoopNT-in 2.7649 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.29, -38.81 APE9-dihe-na -61.85, 160.75 APE8-dihe-in -56.8, 124.98 APE8-rot-in 313.47 APE67-dihe-in -60.01, -18.82 -53.88, -51.43 APE12-dist-out 14.5856 APE11-dist-in 11.2771 APE10-dist-in 7.3858 APE9-dist-in 4.3302 None None CME127,CME161 XRAY 1.82 0.165 0.21 A 368.0 345.0 0 31 31 0 [[25, 313]] 1.0 6ge0 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6GJDA P28482 10 357 360.0 F0E:411 Type1.5_Front Inactive DFGin 6.7097 16.462 BLAminus -129.58, 174.41 70.7, 91.35 -105.73, 20.26 284.72, 79.09 -64.64, -25.49 in-in in 9.6204 Saltbr-in 2.671 HRD-in -72.09, -52.59 71.97, 4.09 in-in-out SNCiio in-out ActLoopNT-in 2.7977 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.38, -38.44 APE9-dihe-na -62.52, 167.01 APE8-dihe-in -77.48, 126.95 APE8-rot-in 303.11 APE67-dihe-in -62.52, -19.79 -59.63, -41.94 APE12-dist-out 14.4021 APE11-dist-in 11.2419 APE10-dist-in 6.9796 APE9-dist-in 4.093 None None CME161 XRAY 1.58 0.169 0.21 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 6gjd CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7AUVA P28482 11 357 360.0 RYW:405 Type1.5_Front Inactive DFGin 7.0231 16.5748 BLAminus -127.45, 177.69 56.53, 84.41 -94.89, 19.78 285.74, 75.17 -78.04, -13.36 out-in out 10.2302 Saltbr-in 2.7195 HRD-in -72.53, -48.67 70.65, 1.51 in-in-out SNCiio in-out ActLoopNT-in 2.8161 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -92.76, -42.85 APE9-dihe-na -53.93, 163.97 APE8-dihe-in -75.48, 124.43 APE8-rot-in 308.53 APE67-dihe-in -70.04, -12.97 -52.3, -46.84 APE12-dist-out 14.9893 APE11-dist-in 11.5904 APE10-dist-in 7.3836 APE9-dist-in 4.2276 None None CME161 XRAY 1.76 0.17 0.229 A 368.0 347.0 0 31 31 0 [[25, 313]] 1.0 7auv CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7NQQA P28482 11 356 360.0 UMN:406 Type1.5_Front Inactive DFGin 6.9179 16.4916 BLAminus -130.12, 174.13 62.32, 86.15 -100.4, 23.58 286.24, 72.55 -69.75, -20.62 in-in in 9.4689 Saltbr-in 2.6775 HRD-in -65.77, -47.18 66.3, 4.45 in-in-out SNCiio in-out ActLoopNT-in 2.8368 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.75, -32.6 APE9-dihe-na -69.61, 163.37 APE8-dihe-in -60.6, 124.16 APE8-rot-in 315.24 APE67-dihe-in -60.72, -19.47 -52.29, -51.54 APE12-dist-out 14.8002 APE11-dist-in 11.3736 APE10-dist-in 7.4019 APE9-dist-in 4.3443 None None CME161 XRAY 1.943 0.177 0.228 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 7nqq CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7NQWA P28482 11 356 360.0 UNW:405 Type1.5_Front Inactive DFGin 6.8164 16.4185 BLAminus -126.85, 178.18 67.17, 79.44 -98.87, 21.06 284.86, 74.28 -63.45, -23.61 in-in in 9.7825 Saltbr-in 2.5108 HRD-in -71.96, -49.6 74.37, 1.07 in-in-out SNCiio in-out ActLoopNT-in 2.8378 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.4, -37.94 APE9-dihe-na -67.38, 158.88 APE8-dihe-in -52.66, 123.57 APE8-rot-in 311.73 APE67-dihe-in -63.22, -17.02 -54.57, -47.98 APE12-dist-out 14.6259 APE11-dist-in 11.2631 APE10-dist-in 7.1864 APE9-dist-in 4.3805 None None CME161 XRAY 1.775 0.167 0.206 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 7nqw CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7NR5A P28482 11 357 360.0 UOH:405 Type1.5_Front Inactive DFGin 7.1423 16.5156 BLAminus -128.99, 175.71 60.33, 87.75 -101.3, 22.07 283.66, 79.18 -76.03, -20.46 out-in out 10.1304 Saltbr-in 2.6875 HRD-in -71.53, -48.61 67.4, 6.67 in-in-out SNCiio in-out ActLoopNT-in 2.8315 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -66.22, 143.49 APE9-dihe-na 70.29, 179.11 APE8-dihe-in -86.54, 137.23 APE8-rot-in 294.6 APE67-dihe-in -64.14, -18.44 -44.13, -48.47 APE12-dist-in 13.3947 APE11-dist-in 11.5169 APE10-dist-out 9.1457 APE9-dist-in 3.1166 None None CME161 XRAY 1.766 0.176 0.223 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 7nr5 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7NR8A P28482 11 356 360.0 UOE:408 Type1.5_Front Inactive DFGin 6.7887 16.6215 BLAminus -131.19, 173.71 59.31, 84.45 -94.57, 22.79 284.69, 71.84 -65.62, -20.38 in-in in 9.9925 Saltbr-in 2.554 HRD-in -71.25, -47.16 78.03, -4.67 in-in-out SNCiio in-out ActLoopNT-in 2.8379 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.57, -40.56 APE9-dihe-na -62.09, 161.08 APE8-dihe-in -53.56, 123.22 APE8-rot-in 309.14 APE67-dihe-in -64.63, -17.01 -54.92, -46.72 APE12-dist-out 14.7709 APE11-dist-in 11.4316 APE10-dist-in 7.4448 APE9-dist-in 4.4485 None None CME161 XRAY 1.627 0.173 0.213 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 7nr8 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 7NR9A P28482 11 355 360.0 UOW:402 Type1.5_Front Inactive DFGin 7.1788 16.4455 BLAminus -121.95, 178.87 51.29, 96.32 -108.0, 26.49 285.39, 78.02 -83.88, -16.22 out-in out 10.2063 Saltbr-in 3.2726 HRD-in -66.46, -47.39 67.01, 11.43 in-in-out SNCiio in-out ActLoopNT-in 2.8907 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -152.12, -19.83 APE9-dihe-na -57.71, 157.85 APE8-dihe-in -80.51, 146.4 APE8-rot-in 299.55 APE67-dihe-in -65.28, -14.73 -65.27, -45.43 APE12-dist-out 14.6652 APE11-dist-in 11.277 APE10-dist-in 7.2977 APE9-dist-in 3.5596 None None CME161 XRAY 1.906 0.248 0.308 A 368.0 335.0 0 31 31 0 [[25, 313]] 1.0 7nr9 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6QAQA P28482 11 357 360.0 HVQ:405,HVQ:406 Type3,Allosteric Inactive DFGin 6.7435 16.3369 BLAminus -132.48, -175.44 58.62, 75.9 -89.63, 27.24 287.47, 77.62 -68.43, -20.91 out-out out 10.3958 Saltbr-out 7.243 HRD-in -74.45, -53.84 73.42, -0.11 out-in-in SNCoii in-in ActLoopNT-in 2.7384 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -80.4, -31.75 APE9-dihe-na -86.25, 162.01 APE8-dihe-in -58.15, 125.86 APE8-rot-in 312.66 APE67-dihe-in -63.66, -17.77 -47.47, -55.55 APE12-dist-in 13.8408 APE11-dist-in 10.7951 APE10-dist-in 6.2969 APE9-dist-in 4.414 None None CME161 XRAY 1.58 0.19 0.229 A 368.0 344.0 0 31 31 0 [[25, 313]] 1.0 6qaq CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FV4A P28482 9 357 360.0 EK7:60401 Type1 None DFGin 6.9263 15.4894 BLAminus -127.76, 178.3 63.88, 86.85 -108.47, 28.84 281.36, 73.37 -69.43, -40.09 in-in in 9.6423 Saltbr-in 2.6484 HRD-in -75.2, -46.77 73.02, -3.37 in-in-none SNCiin in-none ActLoopNT-in 2.8368 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -41.0 APE9-dihe-na -73.39, 169.26 APE8-dihe-in -71.16, 102.82 APE8-rot-in 309.16 APE67-dihe-in -58.85, -32.49 -29.11, -51.69 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.3768 APE9-dist-in 4.3706 None None CME161 XRAY 2.5 0.219 0.253 A 360.0 330.0 19 31 19 12 [[25, 313]] 1.0 4fv4 CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FV5A P28482 9 357 360.0 EK9:60401 Type1 None DFGin 6.9108 15.4358 BLAminus -125.94, 174.49 65.85, 87.03 -106.87, 28.63 280.66, 75.44 -65.59, -45.85 in-in in 9.3535 Saltbr-in 2.7097 HRD-in -72.18, -50.7 73.7, -7.14 in-in-none SNCiin in-none ActLoopNT-in 2.767 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 177.89 APE8-dihe-in -70.68, 121.16 APE8-rot-in 311.58 APE67-dihe-in -59.32, -29.75 -54.36, -44.45 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.6417 None None CME161 XRAY 2.4 0.206 0.248 A 360.0 331.0 18 31 17 14 [[25, 313]] 1.0 4fv5 CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FV6A P28482 9 357 360.0 E57:60401 Type1 None DFGin 6.9518 14.8135 BLAminus -126.85, -179.36 58.14, 87.74 -105.16, 32.96 280.54, 72.76 -66.83, -48.49 in-in in 9.1188 Saltbr-in 2.7279 HRD-in -73.71, -49.52 71.01, 1.58 in-in-none SNCiin in-none ActLoopNT-in 2.7775 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 164.79 APE8-dihe-in -71.11, 129.52 APE8-rot-in 305.06 APE67-dihe-in -62.14, -26.42 -57.08, -45.77 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.348 None None None XRAY 2.5 0.222 0.249 A 360.0 332.0 17 31 17 14 [[25, 313]] 1.0 4fv6 CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FV8A P28482 8 357 360.0 E63:60401 Type1 None DFGin 7.006 15.497 BLAminus -127.0, -178.27 61.48, 83.09 -106.04, 21.77 282.14, 67.68 -61.35, -37.24 in-in in 9.5314 Saltbr-in 2.8516 HRD-in -71.05, -46.98 70.21, -0.53 in-in-none SNCiin in-none ActLoopNT-in 2.737 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -57.07 APE9-dihe-na -109.25, -165.95 APE8-dihe-in -76.52, 120.67 APE8-rot-in 315.06 APE67-dihe-in -62.49, -24.63 -55.08, -35.49 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.5361 APE9-dist-in 4.7209 None None CME161 XRAY 2.0 0.188 0.227 A 360.0 334.0 16 31 18 13 [[25, 313]] 1.0 4fv8 CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 4FV9A P28482 8 357 360.0 E71:60401 Type1 None DFGin 6.9285 15.6357 BLAminus -132.32, -178.13 60.98, 82.89 -105.46, 23.11 283.0, 73.52 -62.53, -38.05 in-in in 9.598 Saltbr-in 3.0385 HRD-in -72.61, -49.16 72.56, -1.28 in-in-none SNCiin in-none ActLoopNT-in 2.7432 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 179.68 APE8-dihe-in -79.93, 120.69 APE8-rot-in 307.61 APE67-dihe-in -59.23, -20.77 -43.94, -53.86 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.5688 None None CME161 XRAY 2.11 0.201 0.238 A 360.0 332.0 18 31 17 14 [[25, 313]] 1.0 4fv9 CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5BUEA P28482 11 358 360.0 4V8:60401 Type1 None DFGin 6.9001 15.2237 BLAminus -122.39, -177.08 63.38, 82.69 -105.24, 21.84 282.5, 70.9 -61.62, -35.58 in-in in 9.2556 Saltbr-in 2.813 HRD-in -71.44, -49.4 73.74, -0.74 in-in-none SNCiin in-none ActLoopNT-in 2.7935 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 136.04 APE8-rot-in 329.09 APE67-dihe-in -60.95, -23.57 -107.06, -4.75 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.4 0.185 0.23 A 361.0 329.0 19 31 16 15 [[25, 313]] 1.0 5bue CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5BUIA P28482 11 358 360.0 4V9:60402 Type1 None DFGin 6.9906 15.3004 BLAminus -130.19, 179.53 65.05, 80.02 -99.3, 20.21 283.96, 66.32 -59.55, -33.7 in-in in 9.5493 Saltbr-in 2.722 HRD-in -68.56, -51.77 75.84, -7.59 in-in-none SNCiin in-none ActLoopNT-in 2.8456 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -130.01 APE8-rot-in 334.62 APE67-dihe-in -56.78, -27.08 -106.13, -3.49 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.12 0.172 0.222 A 361.0 338.0 10 31 21 10 [[25, 313]] 1.0 5bui CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5BUJA P28482 9 358 360.0 4VB:60401 Type1 None DFGin 6.9988 15.405 BLAminus -125.43, -179.58 67.11, 82.68 -104.4, 22.22 283.46, 67.98 -61.34, -32.84 in-in in 9.5259 Saltbr-in 2.6939 HRD-in -77.84, -46.67 74.74, -8.15 in-in-none SNCiin in-none ActLoopNT-in 2.7868 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 127.23 APE8-rot-in 314.32 APE67-dihe-in -58.67, -24.13 -104.72, -0.52 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.85 0.173 0.206 A 361.0 331.0 19 31 16 15 [[25, 313]] 1.0 5buj CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5BVDA P28482 9 358 360.0 4VF:60401 Type1 None DFGin 7.0124 14.8201 BLAminus -120.88, -174.96 58.49, 83.25 -99.87, 23.43 283.53, 71.8 -56.85, -34.73 in-in in 9.2645 Saltbr-in 2.6271 HRD-in -80.64, -49.81 78.16, -6.37 in-in-none SNCiin in-none ActLoopNT-in 2.7197 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 122.19 APE8-rot-in 306.38 APE67-dihe-in -62.44, -24.22 -51.26, -49.02 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.9 0.172 0.207 A 361.0 330.0 20 31 15 16 [[25, 313]] 1.0 5bvd CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5BVEA P28482 9 358 360.0 4VG:60401 Type1 None DFGin 6.9949 14.7747 BLAminus -125.12, -174.29 54.55, 82.42 -96.55, 21.3 282.29, 70.85 -61.67, -24.38 in-in in 9.1394 Saltbr-in 2.729 HRD-in -80.4, -49.72 75.16, -2.3 in-in-none SNCiin in-none ActLoopNT-in 2.781 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 121.36 APE8-rot-in 307.25 APE67-dihe-in -61.28, -26.45 -50.74, -47.6 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.0 0.175 0.22 A 361.0 330.0 20 31 15 16 [[25, 313]] 1.0 5bve CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 5BVFA P28482 9 358 360.0 4VJ:60401 Type1 None DFGin 6.8009 14.7141 BLAminus -123.98, -172.37 55.64, 78.56 -97.05, 25.41 283.39, 68.26 -60.16, -26.7 in-in in 9.2625 Saltbr-in 2.6896 HRD-in -79.7, -47.41 71.71, 1.48 in-in-none SNCiin in-none ActLoopNT-in 2.6907 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -57.62, -24.81 999.0, -48.13 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.9 0.183 0.221 A 361.0 327.0 23 31 14 17 [[25, 313]] 1.0 5bvf CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 3I5ZA P28482 8 357 360.0 Z48:60401 Type1 None DFGin 6.9174 15.2488 BLAminus -127.32, 174.22 70.2, 66.73 -83.95, 23.54 288.3, 68.12 -65.3, -33.09 in-in in 9.3126 Saltbr-in 2.7151 HRD-in -75.44, -48.03 71.03, -6.74 in-in-none SNCiin in-none ActLoopNT-in 2.7171 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -13.55 APE9-dihe-na -121.16, 175.77 APE8-dihe-in -61.26, 116.09 APE8-rot-in 314.5 APE67-dihe-in -57.72, -29.32 -61.25, -36.48 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.8123 APE9-dist-in 4.9538 None None None XRAY 2.2 0.217 0.258 A 380.0 331.0 19 31 17 14 [[25, 313]] 1.0 3i5z CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 3I60A P28482 8 358 360.0 E86:60401 Type1 None DFGin 6.9679 15.1526 BLAminus -121.98, 176.49 63.3, 79.85 -98.81, 21.48 280.47, 70.03 -59.78, -40.19 in-in in 9.2893 Saltbr-in 3.1109 HRD-in -73.88, -46.85 79.23, -3.42 in-in-none SNCiin in-none ActLoopNT-in 2.7524 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -172.19 APE8-dihe-in -93.47, 121.54 APE8-rot-in 308.65 APE67-dihe-in -68.68, -19.01 -43.75, -44.65 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.4957 None None None XRAY 2.5 0.211 0.248 A 380.0 335.0 16 31 18 13 [[25, 313]] 1.0 3i60 CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 6OPIA P28482 10 356 360.0 N0V:60401 Type1.5_Front None DFGin 6.8164 16.4941 BLAminus -135.48, 169.13 71.03, 93.69 -111.04, 34.22 293.24, 78.08 -67.49, -29.15 in-in in 9.8919 Saltbr-in 3.0541 HRD-in -72.72, -50.31 76.41, -2.79 in-in-none SNCiin in-none ActLoopNT-in 2.8075 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 138.69 APE8-rot-in 306.85 APE67-dihe-in -62.81, -15.96 -67.99, -45.38 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None TPO185,PTR187 TPO185,PTR187 XRAY 3.0 0.189 0.26 A 354.0 326.0 17 31 19 12 [[25, 313]] 1.0 6opi CMGC_MAPK1_HUMAN CMGC 8.6e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

CMGC_MAPK1 (Mitogen-activated protein kinase 1)

Total number of chains: 256
Active chains: 16
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 250 97.7% AF-P28482-K1A
DFGin ABAminus 3 1.2% 1WZYA
DFGin None 1 0.4% 6FJZA
DFGout None 1 0.4% 4I5HA
None None 1 0.4% 6RFOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAPK1 MK01_HUMAN 6OPGA P28482 10 358 360.0 ANP:60401 ATPlike Active DFGin 6.5353 14.6675 BLAminus -130.49, -173.97 55.35, 72.85 -87.66, 25.26 285.94, 65.79 -65.31, -19.22 in-in in 9.0658 Saltbr-in 2.6952 HRD-in -72.87, -54.34 77.9, 3.87 in-in-in SNCiii in-in ActLoopNT-in 2.7583 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -102.35, 163.88 APE9-dihe-na 79.13, 168.47 APE8-dihe-in -88.92, 138.85 APE8-rot-in 292.11 APE67-dihe-in -68.23, -14.82 -51.35, -45.86 APE12-dist-in 12.5703 APE11-dist-in 11.1338 APE10-dist-in 6.6534 APE9-dist-in 2.9424 None TPO185,PTR187 TPO185,PTR187 XRAY 2.9 0.16 0.239 A 354.0 349.0 0 31 31 0 [[25, 313]] 1.0 6opg Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.6e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5V60A P28482 10 358 360.0 ACP:401 ATPlike Active DFGin 6.6686 14.8874 BLAminus -124.21, -175.27 60.56, 75.29 -91.11, 25.45 286.11, 68.09 -67.4, -23.76 in-in in 9.2691 Saltbr-in 3.0882 HRD-in -75.88, -52.24 69.24, 12.32 in-in-in SNCiii in-in ActLoopNT-in 2.9513 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -89.66, 171.23 APE9-dihe-na 66.7, 168.41 APE8-dihe-in -89.68, 141.19 APE8-rot-in 301.48 APE67-dihe-in -66.12, -19.67 -43.41, -50.15 APE12-dist-in 12.5737 APE11-dist-in 11.0864 APE10-dist-in 6.6326 APE9-dist-in 2.9874 None TPO185,PTR187 TPO185,PTR187 XRAY 2.18 0.193 0.226 A 356.0 349.0 0 31 31 0 [[25, 313]] 1.0 5v60 Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN AF-P28482-K1A P28482 17 321 360.0 No_ligand No_ligand Active DFGin 6.7095 15.0324 BLAminus -132.81, 178.26 60.0, 67.32 -79.82, 13.55 287.23, 76.28 -59.44, -30.59 in-in in 9.2916 Saltbr-in 2.7372 HRD-in -72.76, -45.83 65.72, 5.09 in-in-in SNCiii in-in ActLoopNT-in 2.8716 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -80.26, 168.0 APE9-dihe-na 60.74, 145.84 APE8-dihe-in -61.61, 133.3 APE8-rot-in 298.45 APE67-dihe-in -68.84, -20.54 -48.48, -45.65 APE12-dist-in 12.8219 APE11-dist-in 11.2042 APE10-dist-in 6.9498 APE9-dist-in 3.0736 None None None AF2 -1.0 1.0 1.0 A 305.0 305.0 0 31 31 0 [[25, 313]] 1.0 AF-P28482-K1 Homo sapiens CMGC_MAPK1_HUMAN CMGC 5e-86 294.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN AF-P28482-K3A P28482 17 321 360.0 No_ligand No_ligand Active DFGin 6.7222 14.81 BLAminus -134.49, 179.63 60.4, 61.52 -74.0, 13.5 286.26, 78.19 -60.59, -24.27 in-in in 9.4022 Saltbr-in 2.8005 HRD-in -75.01, -46.98 64.78, 12.11 in-in-in SNCiii in-in ActLoopNT-in 2.8388 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -117.94, 171.15 APE9-dihe-na 58.96, 136.08 APE8-dihe-in -57.85, 133.77 APE8-rot-in 294.09 APE67-dihe-in -67.48, -19.97 -48.51, -44.4 APE12-dist-in 13.0255 APE11-dist-in 10.751 APE10-dist-in 6.4788 APE9-dist-in 3.0995 None None None AF2 -1.0 1.0 1.0 A 305.0 305.0 0 31 31 0 [[25, 313]] 1.0 AF-P28482-K3 Homo sapiens CMGC_MAPK1_HUMAN CMGC 5e-86 294.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5V61A P28482 10 359 360.0 No_ligand No_ligand Active DFGin 6.6537 15.6953 BLAminus -127.45, -177.89 71.76, 74.38 -98.23, 26.0 278.7, 71.15 -67.96, -26.05 in-in in 9.6567 Saltbr-in 2.6849 HRD-in -74.15, -53.14 74.14, 10.93 in-in-in SNCiii in-in ActLoopNT-in 2.8197 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -93.7, 172.55 APE9-dihe-na 68.11, 165.25 APE8-dihe-in -89.72, 145.0 APE8-rot-in 300.7 APE67-dihe-in -67.44, -18.57 -46.35, -49.99 APE12-dist-in 12.4561 APE11-dist-in 11.172 APE10-dist-in 6.5301 APE9-dist-in 2.9821 None TPO185,PTR187 TPO185,PTR187 XRAY 2.2 0.178 0.212 A 356.0 350.0 0 31 31 0 [[25, 313]] 1.0 5v61 Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6OPHA P28482 11 358 360.0 6QB:60401 Type1 Active DFGin 6.7981 15.0588 BLAminus -130.04, 176.89 62.64, 86.8 -99.79, 23.69 285.42, 69.18 -59.71, -37.46 in-in in 9.1055 Saltbr-in 2.7 HRD-in -73.41, -55.53 80.22, 3.3 in-in-in SNCiii in-in ActLoopNT-in 2.9027 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -99.5, 167.6 APE9-dihe-na 71.49, 153.42 APE8-dihe-in -69.32, 138.47 APE8-rot-in 307.19 APE67-dihe-in -58.06, -18.68 -49.97, -53.1 APE12-dist-in 12.741 APE11-dist-in 11.1224 APE10-dist-in 6.801 APE9-dist-in 3.0809 None TPO185,PTR187 TPO185,PTR187 XRAY 2.4 0.195 0.243 A 354.0 348.0 0 31 31 0 [[25, 313]] 1.0 6oph Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.6e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8U8JA P28482 7 358 360.0 WAL:60401 Type1 Active DFGin 6.6924 14.6032 BLAminus -129.0, -177.16 58.24, 84.12 -98.97, 25.3 283.6, 66.7 -63.94, -32.37 in-in in 8.7414 Saltbr-in 2.8063 HRD-in -74.57, -53.96 73.73, 13.51 in-in-in SNCiii in-in ActLoopNT-in 2.8191 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.04, 171.8 APE9-dihe-na 68.12, 168.69 APE8-dihe-in -92.27, 141.81 APE8-rot-in 299.3 APE67-dihe-in -59.84, -16.28 -46.87, -56.27 APE12-dist-in 12.6139 APE11-dist-in 11.0733 APE10-dist-in 6.573 APE9-dist-in 2.9829 A7S TPO185,PTR187 TPO185,PTR187 XRAY 2.1 0.18 0.227 A 354.0 352.0 0 31 31 0 [[25, 313]] 1.0 8u8j Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.6e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8U8KA P28482 10 358 360.0 W8U:60401 Type1 Active DFGin 6.7234 14.4664 BLAminus -129.74, -176.79 54.57, 88.21 -99.75, 25.02 286.15, 64.72 -60.73, -30.08 in-in in 8.6454 Saltbr-in 2.7029 HRD-in -73.18, -50.61 71.52, 11.37 in-in-in SNCiii in-in ActLoopNT-in 2.8181 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -94.55, 172.59 APE9-dihe-na 66.8, 166.42 APE8-dihe-in -88.85, 143.17 APE8-rot-in 296.07 APE67-dihe-in -63.45, -15.66 -52.73, -51.37 APE12-dist-in 12.6541 APE11-dist-in 11.1956 APE10-dist-in 6.7124 APE9-dist-in 2.9607 A7S TPO185,PTR187 TPO185,PTR187 XRAY 2.1 0.176 0.213 A 354.0 349.0 0 31 31 0 [[25, 313]] 1.0 8u8k Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.6e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QTEA P28482 11 358 360.0 390:430 Type1 Active DFGin 6.9092 15.0118 BLAminus -128.11, 177.87 65.48, 81.01 -97.8, 24.52 281.71, 68.7 -63.45, -27.47 in-in in 9.4461 Saltbr-in 2.8495 HRD-in -77.98, -52.32 76.82, 3.18 in-in-in SNCiii in-in ActLoopNT-in 2.7899 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -92.78, -31.85 APE9-dihe-na -67.91, 159.3 APE8-dihe-in -56.84, 129.56 APE8-rot-in 308.17 APE67-dihe-in -65.89, -13.13 -51.33, -50.7 APE12-dist-in 13.9805 APE11-dist-in 11.0006 APE10-dist-in 7.1835 APE9-dist-in 4.3781 None None None XRAY 1.5 0.147 0.167 A 361.0 348.0 0 31 31 0 [[25, 313]] 1.0 4qte Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G54A P28482 10 356 360.0 6H3:403 Type1 Active DFGin 6.8714 16.2079 BLAminus -132.88, -179.11 65.87, 69.62 -92.42, 26.13 283.45, 69.74 -65.96, -27.02 out-in out 10.1983 Saltbr-in 2.7797 HRD-in -75.15, -46.62 69.02, 1.28 in-in-in SNCiii in-in ActLoopNT-in 2.7772 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.74, -31.04 APE9-dihe-na -74.65, 165.75 APE8-dihe-in -65.58, 131.17 APE8-rot-in 305.71 APE67-dihe-in -65.73, -17.41 -55.69, -47.01 APE12-dist-in 13.6771 APE11-dist-in 10.778 APE10-dist-in 6.6196 APE9-dist-in 4.3477 None None None XRAY 2.05 0.185 0.221 A 361.0 347.0 0 31 31 0 [[25, 313]] 1.0 6g54 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7OPMA P28482 1 360 360.0 08G:60401 Type1 Active DFGin 7.0654 15.2747 BLAminus -129.98, -173.24 56.69, 70.0 -91.64, 20.03 282.06, 60.94 -67.35, -36.15 in-in in 9.3584 Saltbr-in 2.8706 HRD-in -71.5, -50.41 70.44, 8.29 in-in-in SNCiii in-in ActLoopNT-in 3.0369 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.91, 154.41 APE9-dihe-na 75.03, 163.11 APE8-dihe-in -83.61, 145.58 APE8-rot-in 304.37 APE67-dihe-in -70.53, -18.9 -53.65, -46.6 APE12-dist-in 12.857 APE11-dist-in 10.6299 APE10-dist-in 6.8222 APE9-dist-in 2.9125 None TPO185,PTR187 TPO185,PTR187 XRAY 2.45 0.237 0.254 A 364.0 360.0 0 31 31 0 [[25, 313]] 1.0 7opm Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5V62A P28482 10 360 360.0 FRZ:406,AKS:407 Type1,Type1 Active DFGin 6.7632 15.4903 BLAminus -124.1, -176.99 62.38, 83.65 -99.36, 23.82 282.86, 70.28 -72.33, -19.01 in-in in 9.4684 Saltbr-in 2.7517 HRD-in -71.83, -53.45 74.5, 7.81 in-in-in SNCiii in-in ActLoopNT-in 2.8475 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -92.82, 173.28 APE9-dihe-na 63.65, 166.64 APE8-dihe-in -87.4, 138.22 APE8-rot-in 297.67 APE67-dihe-in -61.77, -20.72 -44.24, -52.92 APE12-dist-in 12.7519 APE11-dist-in 11.496 APE10-dist-in 6.8896 APE9-dist-in 3.011 None TPO185,PTR187 TPO185,PTR187 XRAY 1.9 0.172 0.203 A 351.0 351.0 0 31 31 0 [[25, 313]] 1.0 5v62 Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.4e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8PVUE P28482 24 356 360.0 No_ligand No_ligand Inactive DFGin 7.5932 17.6539 ABAminus -114.83, -57.91 -91.0, 132.04 -139.19, 12.86 275.21, 83.7 -61.84, -46.11 out-out out 10.7362 Saltbr-out 8.7045 HRD-out -102.83, 165.82 -156.25, 160.83 out-in-out SNCoio in-out ActLoopNT-in 2.7273 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -111.07, 147.6 APE9-dihe-na -61.46, -46.75 APE8-dihe-in -129.35, 137.9 APE8-rot-out 88.46 APE67-dihe-in -64.45, -31.6 -96.79, 2.11 APE12-dist-in 7.989 APE11-dist-in 11.069 APE10-dist-out 8.9712 APE9-dist-out 10.4542 None None None EM 3.5 999.0 999.0 E 361.0 301.0 26 31 21 10 [[25, 313]] 1.0 8pvu Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 1WZYA P28482 8 357 360.0 F29:1001 Type1 Inactive DFGin 6.6131 16.4587 ABAminus -125.93, -57.84 -77.7, 107.83 -107.25, 23.47 285.61, 70.28 -59.34, -21.19 in-in in 9.1317 Saltbr-in 3.0816 HRD-in -62.8, -52.83 70.84, 12.27 in-in-out SNCiio in-out ActLoopNT-in 2.7562 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oioo APE10-dihe-na -46.86, 125.25 APE9-dihe-na -155.12, -47.66 APE8-dihe-out 71.65, 79.94 APE8-rot-in 312.9 APE67-dihe-out -142.94, -5.88 -171.91, -165.7 APE12-dist-out 15.2135 APE11-dist-in 10.1751 APE10-dist-out 10.4542 APE9-dist-out 7.3014 None None None XRAY 2.5 0.253 0.292 A 368.0 350.0 0 31 31 0 [[25, 313]] 1.0 1wzy Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 1TVOA P28482 8 357 360.0 FRZ:1001 Type1 Inactive DFGin 6.7353 16.5441 ABAminus -143.04, -21.92 -99.58, 92.28 -97.21, 29.04 291.9, 66.95 -57.83, -37.85 in-in in 9.483 Saltbr-in 2.9404 HRD-in -68.59, -45.64 64.32, 6.29 in-in-out SNCiio in-out ActLoopNT-in 2.8901 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.95, -31.57 APE9-dihe-na -57.23, 155.98 APE8-dihe-in -48.99, 121.33 APE8-rot-in 300.25 APE67-dihe-in -55.04, -19.18 -44.3, -60.26 APE12-dist-out 14.2385 APE11-dist-in 11.1478 APE10-dist-in 7.5063 APE9-dist-in 4.4953 None None None XRAY 2.5 0.266 0.272 A 368.0 350.0 0 31 31 0 [[25, 313]] 1.0 1tvo Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4H3QA P28482 9 360 360.0 ANP:401 ATPlike Inactive DFGin 6.6034 15.6819 BLAminus -131.43, 178.9 70.32, 68.42 -96.0, 22.91 290.2, 68.59 -63.35, -20.75 in-in in 9.2328 Saltbr-in 2.8208 HRD-in -71.26, -48.66 68.7, 4.98 in-in-out SNCiio in-out ActLoopNT-in 2.9419 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_iioo APE10-dihe-na -133.14, 155.68 APE9-dihe-na -60.56, -35.88 APE8-dihe-out -124.57, -73.58 APE8-rot-out 150.68 APE67-dihe-out -67.06, -6.51 92.51, -9.23 APE12-dist-in 9.1353 APE11-dist-in 11.6615 APE10-dist-out 8.7525 APE9-dist-out 10.9003 R77A,C161S,I255G,E314A None None XRAY 2.2 0.184 0.232 A 362.0 352.0 0 31 31 0 [[25, 313]] 1.0 4h3q Homo sapiens CMGC_MAPK1_HUMAN CMGC 3.4e-85 291.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4IZ5A P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.5744 16.2257 BLAminus -133.03, 170.47 61.68, 96.87 -113.24, 29.97 280.98, 72.88 -75.05, -15.97 in-out in 8.9431 Saltbr-out 6.3365 HRD-in -70.37, -54.19 76.22, -6.05 out-in-out SNCoio in-out ActLoopNT-in 2.8045 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -135.59, 107.64 APE9-dihe-na -86.59, -36.52 APE8-dihe-in -63.86, 130.93 APE8-rot-in 305.07 APE67-dihe-in -64.33, -26.99 -124.19, 30.24 APE12-dist-in 10.0117 APE11-dist-out 7.082 APE10-dist-out 8.2491 APE9-dist-out 10.5104 T185E None None XRAY 3.19 0.245 0.292 A 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 Homo sapiens CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4IZ5B P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.6142 16.236 BLAminus -130.77, 169.05 63.18, 96.88 -112.33, 27.86 280.9, 72.0 -73.48, -17.21 in-out in 8.9516 Saltbr-out 6.2842 HRD-in -71.55, -52.24 74.21, -4.59 out-in-out SNCoio in-out ActLoopNT-in 2.846 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -135.05, 108.67 APE9-dihe-na -88.18, -35.19 APE8-dihe-in -65.83, 129.75 APE8-rot-in 303.93 APE67-dihe-in -64.9, -24.28 -122.7, 29.42 APE12-dist-in 10.0315 APE11-dist-out 7.0852 APE10-dist-out 8.2498 APE9-dist-out 10.5027 T185E None None XRAY 3.19 0.245 0.292 B 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 Homo sapiens CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4IZ5C P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.6044 16.2316 BLAminus -131.01, 170.44 62.04, 96.83 -112.78, 28.94 280.74, 73.4 -74.17, -17.63 in-out in 8.9448 Saltbr-out 6.3598 HRD-in -72.88, -51.67 75.48, -6.0 out-in-out SNCoio in-out ActLoopNT-in 2.8678 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -133.99, 108.02 APE9-dihe-na -87.46, -36.5 APE8-dihe-in -65.77, 130.32 APE8-rot-in 303.26 APE67-dihe-in -66.37, -24.82 -122.99, 29.53 APE12-dist-in 10.0145 APE11-dist-out 7.0682 APE10-dist-out 8.2202 APE9-dist-out 10.4967 T185E None None XRAY 3.19 0.245 0.292 C 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 Homo sapiens CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4IZ5D P28482 11 357 360.0 ADP:900 ATPlike Inactive DFGin 6.6009 16.2317 BLAminus -131.94, 170.02 62.64, 97.08 -112.75, 27.73 280.79, 72.08 -72.23, -17.73 in-out in 8.9604 Saltbr-out 6.3214 HRD-in -71.89, -53.7 75.24, -4.58 out-in-out SNCoio in-out ActLoopNT-in 2.8465 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -135.09, 108.16 APE9-dihe-na -88.37, -35.4 APE8-dihe-in -66.59, 130.93 APE8-rot-in 303.88 APE67-dihe-in -65.41, -25.44 -123.75, 30.53 APE12-dist-in 10.0122 APE11-dist-out 7.0881 APE10-dist-out 8.224 APE9-dist-out 10.4605 T185E None None XRAY 3.19 0.245 0.292 D 356.0 347.0 0 31 31 0 [[25, 313]] 1.0 4iz5 Homo sapiens CMGC_MAPK1_HUMAN CMGC 2.5e-85 292.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 2Y9QA P28482 9 358 360.0 ANP:1359 ATPlike Inactive DFGin 6.7756 15.4463 BLAminus -131.56, -173.58 71.27, 62.6 -94.15, 18.41 284.56, 67.7 -60.61, -22.82 in-in in 9.1065 Saltbr-in 2.7907 HRD-in -69.38, -48.16 75.91, -5.63 in-in-out SNCiio in-out ActLoopNT-in 2.7879 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -136.29, 162.19 APE9-dihe-na -69.67, -30.11 APE8-dihe-in -153.45, 140.36 APE8-rot-out 183.83 APE67-dihe-in -69.16, -12.41 -110.3, 4.7 APE12-dist-in 9.6632 APE11-dist-in 12.83 APE10-dist-out 9.194 APE9-dist-out 11.5088 None None None XRAY 1.55 0.156 0.177 A 362.0 350.0 0 31 31 0 [[25, 313]] 1.0 2y9q Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.3e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FMQA P28482 9 358 360.0 ANP:401 ATPlike Inactive DFGin 6.797 15.309 BLAminus -133.64, -170.94 67.61, 66.1 -98.24, 21.64 282.65, 68.61 -61.3, -22.42 in-in in 9.1314 Saltbr-in 2.9364 HRD-in -73.07, -47.52 74.25, -10.43 in-in-out SNCiio in-out ActLoopNT-in 2.8302 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -138.4, 159.9 APE9-dihe-na -70.94, -24.68 APE8-dihe-in -158.11, 141.22 APE8-rot-out 179.47 APE67-dihe-in -66.85, -11.48 -113.88, 6.26 APE12-dist-in 9.4738 APE11-dist-in 12.7001 APE10-dist-out 9.2253 APE9-dist-out 11.64 None None None XRAY 2.098 0.182 0.224 A 362.0 350.0 0 31 31 0 [[25, 313]] 1.0 4fmq Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.3e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4NIFB P28482 9 360 360.0 ANP:401 ATPlike Inactive DFGin 6.7638 15.4088 BLAminus -131.87, -169.42 69.51, 63.01 -98.39, 22.71 281.57, 68.87 -63.28, -26.61 in-in in 9.0075 Saltbr-in 2.7834 HRD-in -68.77, -49.09 76.18, -3.84 in-in-out SNCiio in-out ActLoopNT-in 2.7275 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -127.8, 161.08 APE9-dihe-na -75.51, -26.3 APE8-dihe-in -152.23, 138.84 APE8-rot-out 180.18 APE67-dihe-in -71.26, -8.82 -111.88, 5.33 APE12-dist-in 8.1996 APE11-dist-in 11.9615 APE10-dist-out 8.903 APE9-dist-out 11.5131 None None None XRAY 2.15 0.161 0.208 B 362.0 349.0 3 31 28 3 [[25, 313]] 1.0 4nif Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.3e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4NIFE P28482 10 360 360.0 ANP:401 ATPlike Inactive DFGin 6.7991 15.6006 BLAminus -132.52, -168.43 65.68, 64.41 -97.79, 21.09 277.61, 67.0 -63.55, -23.2 in-in in 9.1704 Saltbr-in 2.7133 HRD-in -70.38, -48.01 73.58, -2.52 in-in-out SNCiio in-out ActLoopNT-in 2.7288 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -128.04, 157.14 APE9-dihe-na -71.47, -27.38 APE8-dihe-in -153.58, 137.78 APE8-rot-out 179.37 APE67-dihe-in -68.22, -5.95 -110.7, 4.02 APE12-dist-in 8.1436 APE11-dist-in 11.9289 APE10-dist-out 8.9408 APE9-dist-out 11.5278 None None None XRAY 2.15 0.161 0.208 E 362.0 348.0 3 31 28 3 [[25, 313]] 1.0 4nif Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.3e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8PSRA P28482 1 358 360.0 ANP:401 ATPlike Inactive DFGin 6.7627 15.1158 BLAminus -130.96, -167.28 68.25, 62.57 -95.64, 20.11 282.69, 71.74 -68.98, -15.25 in-in in 8.941 Saltbr-in 2.8232 HRD-in -68.74, -46.55 75.16, -5.99 in-in-out SNCiio in-out ActLoopNT-in 2.7689 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -133.02, 153.53 APE9-dihe-na -66.89, -30.36 APE8-dihe-in -146.2, 134.03 APE8-rot-out 178.25 APE67-dihe-in -71.02, -10.13 -100.56, 5.83 APE12-dist-in 8.1678 APE11-dist-in 11.5467 APE10-dist-out 8.8891 APE9-dist-out 11.3605 None None None XRAY 1.85 0.183 0.209 A 364.0 354.0 4 31 27 4 [[25, 313]] 1.0 8psr Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 3TEIA P28482 10 358 360.0 ANP:401 ATPlike Inactive DFGin 6.743 15.9468 BLAminus -130.8, -176.53 59.31, 74.36 -93.64, 10.5 288.08, 72.41 -50.44, -31.09 in-in in 9.2714 Saltbr-in 3.1994 HRD-in -69.93, -52.25 74.6, -17.82 in-in-out SNCiio in-out ActLoopNT-in 2.7526 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na 66.02, 77.59 APE9-dihe-na -53.11, -45.5 APE8-dihe-in -109.04, 134.77 APE8-rot-out 40.2 APE67-dihe-in -60.63, -33.66 -94.81, 4.48 APE12-dist-in 8.7836 APE11-dist-in 10.9926 APE10-dist-out 8.5071 APE9-dist-out 11.1823 R77A,E314A None None XRAY 2.404 0.199 0.235 A 362.0 339.0 10 31 24 7 [[25, 313]] 1.0 3tei Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4H3PA P28482 11 359 360.0 ANP:401 ATPlike Inactive DFGin 6.7486 16.129 BLAminus -129.02, -179.26 65.06, 71.95 -98.46, 28.28 294.01, 75.31 -57.14, -23.59 in-in in 9.6015 Saltbr-in 3.0521 HRD-in -79.45, -54.12 78.74, 4.99 in-in-out SNCiio in-out ActLoopNT-in 2.7274 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -109.42, 169.7 APE9-dihe-na -56.98, -72.96 APE8-dihe-in -103.33, 144.18 APE8-rot-out 6.69 APE67-dihe-in -56.41, -28.74 -91.67, -5.29 APE12-dist-in 8.8946 APE11-dist-in 9.1851 APE10-dist-out 8.3832 APE9-dist-out 9.7322 R77A,E314A None None XRAY 2.3 0.18 0.224 A 362.0 342.0 7 31 24 7 [[25, 313]] 1.0 4h3p Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4H3PD P28482 11 359 360.0 ANP:401 ATPlike Inactive DFGin 6.7423 16.2695 BLAminus -128.42, -178.25 63.92, 70.53 -94.38, 28.0 287.67, 73.89 -60.9, -21.54 in-in in 9.383 Saltbr-in 3.4542 HRD-in -75.51, -54.76 82.18, -2.55 in-in-out SNCiio in-out ActLoopNT-in 2.6568 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 42.36 APE8-rot-out 66.34 APE67-dihe-in -61.9, -28.03 -63.57, -9.01 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 R77A,E314A None None XRAY 2.3 0.18 0.224 D 362.0 338.0 11 31 20 11 [[25, 313]] 1.0 4h3p Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8PSTA P28482 11 358 360.0 AN2:401,DC6:402 ATPlike,Allosteric Inactive DFGin 6.7851 16.1283 BLAminus -134.06, -179.16 64.02, 73.91 -96.68, 24.07 284.98, 72.99 -65.53, -24.17 in-out in 9.3377 Saltbr-out 3.8743 HRD-in -66.25, -48.73 76.74, -3.29 out-in-out SNCoio in-out ActLoopNT-in 2.739 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -76.72 APE8-dihe-in -121.88, 139.27 APE8-rot-out 177.73 APE67-dihe-in -63.49, -19.48 -93.88, -5.61 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.7648 None None None XRAY 1.9 0.192 0.224 A 364.0 333.0 15 31 18 13 [[25, 313]] 1.0 8pst Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8PSWA P28482 11 358 360.0 AN2:401,D2I:402 ATPlike,Allosteric Inactive DFGin 6.8713 16.2525 BLAminus -133.24, 178.92 60.17, 81.49 -98.82, 18.4 283.05, 77.14 -62.53, -21.73 in-out in 9.4184 Saltbr-out 4.1301 HRD-in -71.12, -49.26 76.63, -3.5 out-in-out SNCoio in-out ActLoopNT-in 2.7674 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nioo APE10-dihe-na -97.92, 161.43 APE9-dihe-na -86.07, -39.89 APE8-dihe-in -109.3, 110.17 APE8-rot-in 302.88 APE67-dihe-in -69.34, -10.4 -107.51, 8.93 APE12-dist-none 999.0 APE11-dist-in 10.1783 APE10-dist-out 8.2941 APE9-dist-out 11.0742 None None None XRAY 2.0 0.191 0.215 A 364.0 338.0 10 31 21 10 [[25, 313]] 1.0 8psw Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8PSYA P28482 11 358 360.0 AN2:401,EI0:402 ATPlike,Allosteric Inactive DFGin 6.977 16.2643 BLAminus -135.96, -178.59 63.47, 73.94 -97.05, 21.62 286.23, 79.85 -63.59, -23.12 in-out in 9.4371 Saltbr-out 4.3597 HRD-in -69.38, -42.87 69.92, -0.29 out-in-out SNCoio in-out ActLoopNT-in 2.8605 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -110.27, 143.52 APE9-dihe-na -55.43, -62.59 APE8-dihe-in -128.8, 133.66 APE8-rot-out 167.71 APE67-dihe-in -72.41, -12.11 -102.66, 18.87 APE12-dist-out 6.7454 APE11-dist-in 10.5215 APE10-dist-out 8.6185 APE9-dist-out 10.4447 None None None XRAY 2.55 0.192 0.232 A 364.0 340.0 8 31 23 8 [[25, 313]] 1.0 8psy Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8PT0A P28482 11 358 360.0 ANP:401,EAI:403 ATPlike,Allosteric Inactive DFGin 6.7034 15.5181 BLAminus -130.99, -173.26 73.92, 62.07 -95.1, 17.63 279.55, 70.77 -68.45, -13.49 in-in in 9.1413 Saltbr-in 2.8701 HRD-in -71.96, -48.9 77.41, -4.12 in-in-out SNCiio in-out ActLoopNT-in 2.6924 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -110.07, -36.78 APE9-dihe-na -83.86, 177.79 APE8-dihe-in -68.52, 145.31 APE8-rot-out 191.04 APE67-dihe-in -66.51, -15.78 -105.25, 7.42 APE12-dist-out 6.875 APE11-dist-in 12.4434 APE10-dist-out 12.5541 APE9-dist-out 9.9942 None None None XRAY 1.65 0.178 0.207 A 364.0 348.0 0 31 31 0 [[25, 313]] 1.0 8pt0 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8PT1A P28482 11 359 360.0 ANP:401,E2A:402 ATPlike,Allosteric Inactive DFGin 6.7525 15.486 BLAminus -130.01, -175.04 73.39, 64.08 -95.46, 18.76 282.28, 68.91 -63.67, -19.55 in-in in 9.1894 Saltbr-in 2.8492 HRD-in -70.21, -47.68 76.07, -5.14 in-in-out SNCiio in-out ActLoopNT-in 2.6722 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -121.06, -17.86 APE9-dihe-na -106.9, -177.78 APE8-dihe-in -78.1, 145.34 APE8-rot-out 186.54 APE67-dihe-in -67.62, -15.27 -108.68, 6.96 APE12-dist-in 7.1713 APE11-dist-in 12.6151 APE10-dist-out 12.6307 APE9-dist-out 10.2747 None None None XRAY 1.8 0.18 0.206 A 364.0 349.0 0 31 31 0 [[25, 313]] 1.0 8pt1 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8PT5A P28482 10 358 360.0 ANP:401,D5R:402 ATPlike,Allosteric Inactive DFGin 6.7902 15.3041 BLAminus -138.03, -165.34 60.19, 62.86 -94.09, 21.06 289.01, 63.44 -59.86, -23.15 in-in in 9.091 Saltbr-in 2.8817 HRD-in -75.18, -47.36 71.89, 2.28 in-in-out SNCiio in-out ActLoopNT-in 2.6856 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -138.15, 158.79 APE9-dihe-na -71.62, -19.38 APE8-dihe-in -154.23, 140.23 APE8-rot-out 183.5 APE67-dihe-in -63.22, -13.66 -125.12, 20.04 APE12-dist-in 7.6307 APE11-dist-in 11.4685 APE10-dist-out 8.7388 APE9-dist-out 11.2872 None None None XRAY 1.95 0.206 0.235 A 364.0 336.0 10 31 21 10 [[25, 313]] 1.0 8pt5 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8R5FA P28482 11 359 360.0 ANP:401,Y3H:403 ATPlike,Allosteric Inactive DFGin 6.7147 15.4588 BLAminus -133.12, -173.02 67.59, 67.52 -98.89, 23.72 283.56, 67.1 -69.6, -17.36 in-in in 9.1414 Saltbr-in 2.9066 HRD-in -75.1, -48.03 76.68, -4.69 in-in-out SNCiio in-out ActLoopNT-in 2.6928 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -92.27 APE8-dihe-in -89.34, 137.7 APE8-rot-out 190.9 APE67-dihe-in -68.19, -17.69 -92.76, -0.83 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 9.6172 None None None XRAY 1.65 0.194 0.218 A 364.0 337.0 12 31 19 12 [[25, 313]] 1.0 8r5f Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7W5OB P28482 12 357 360.0 6GI:606 Allosteric Inactive DFGin 6.7291 15.966 BLAminus -130.99, -179.63 60.79, 79.04 -97.44, 21.46 284.57, 69.25 -51.76, -37.4 in-in in 9.205 Saltbr-in 2.9255 HRD-in -89.57, -49.89 81.11, -2.76 in-in-out SNCiio in-out ActLoopNT-in 2.6945 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -127.79, 113.11 APE9-dihe-na 67.74, 140.06 APE8-dihe-in -61.14, 150.09 APE8-rot-in 295.42 APE67-dihe-in -62.08, -24.55 -59.37, -51.13 APE12-dist-in 8.0847 APE11-dist-out 7.278 APE10-dist-in 7.6425 APE9-dist-in 2.9693 None None NEP125 XRAY 2.35 0.228 0.279 B 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 7w5o Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8PT3A P28482 10 359 360.0 D7O:401,ANP:405 Allosteric,ATPlike Inactive DFGin 6.7463 16.2954 BLAminus -133.05, 179.18 60.24, 82.09 -94.36, 25.54 283.73, 70.47 -58.59, -24.6 in-out in 9.2783 Saltbr-out 4.0942 HRD-in -70.52, -51.82 77.79, -2.53 out-in-out SNCoio in-out ActLoopNT-in 2.7512 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oiio APE10-dihe-na -134.69, 123.91 APE9-dihe-na -78.34, -33.65 APE8-dihe-in -152.41, 145.11 APE8-rot-out 185.39 APE67-dihe-in -63.56, -20.16 -105.73, 9.6 APE12-dist-out 6.368 APE11-dist-in 8.5922 APE10-dist-in 7.9732 APE9-dist-out 9.8583 None None None XRAY 1.8 0.189 0.222 A 364.0 344.0 6 31 25 6 [[25, 313]] 1.0 8pt3 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.5e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6QAHA P28482 11 357 360.0 HVB:402,HVB:403 Allosteric,Allosteric Inactive DFGin 6.7581 16.1676 BLAminus -136.73, 179.29 62.82, 76.94 -93.86, 22.86 290.05, 77.22 -60.46, -27.45 in-out in 9.9877 Saltbr-out 4.0961 HRD-in -76.02, -51.2 74.22, -0.2 out-in-out SNCoio in-out ActLoopNT-in 2.7923 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -88.29, -39.06 APE9-dihe-na -75.24, 163.73 APE8-dihe-in -59.27, 129.3 APE8-rot-in 308.42 APE67-dihe-in -64.98, -18.58 -56.47, -46.56 APE12-dist-out 14.087 APE11-dist-in 10.975 APE10-dist-in 6.6547 APE9-dist-in 4.407 None None CME161 XRAY 1.58 0.182 0.212 A 368.0 340.0 1 31 31 0 [[25, 313]] 1.0 6qah Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6QALA P28482 11 357 360.0 HV2:405,HV2:406 Allosteric,Allosteric Inactive DFGin 6.7663 16.5446 BLAminus -128.18, 174.72 64.17, 81.73 -99.37, 22.14 287.42, 72.94 -62.7, -28.45 in-in in 9.8461 Saltbr-in 3.4028 HRD-in -71.58, -48.42 72.8, 2.63 in-in-out SNCiio in-out ActLoopNT-in 2.7899 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -53.19, 146.61 APE9-dihe-na 64.69, -178.57 APE8-dihe-in -92.49, 143.95 APE8-rot-in 292.68 APE67-dihe-in -64.62, -19.41 -47.49, -52.39 APE12-dist-in 13.4343 APE11-dist-in 11.3908 APE10-dist-out 8.7984 APE9-dist-in 3.1299 None None CME161 XRAY 1.57 0.18 0.223 A 368.0 336.0 3 31 31 0 [[25, 313]] 1.0 6qal Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6NBSA P28482 10 356 360.0 KJ7:60403,KJ4:60404 Allosteric,Allosteric Inactive DFGin 6.8606 16.4381 BLAminus -130.15, -176.79 62.06, 79.39 -99.12, 19.64 285.27, 77.93 -63.72, -24.16 out-out out 10.0889 Saltbr-out 4.0562 HRD-in -72.23, -53.85 78.37, 1.37 out-in-out SNCoio in-out ActLoopNT-in 2.7647 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -111.09, -39.9 APE9-dihe-na -62.98, 162.81 APE8-dihe-in -62.93, 129.71 APE8-rot-in 305.16 APE67-dihe-in -63.54, -20.73 -58.96, -45.64 APE12-dist-out 14.3826 APE11-dist-in 11.2122 APE10-dist-in 7.1517 APE9-dist-in 4.2928 None None None XRAY 1.9 0.182 0.222 A 367.0 342.0 0 31 31 0 [[25, 313]] 1.0 6nbs Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.4e-85 293.1 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AOGA P28482 11 356 360.0 N29:404,N29:405,N29:406 Allosteric,Allosteric,Type1 Inactive DFGin 6.797 16.4858 BLAminus -133.77, 177.3 62.93, 83.71 -95.49, 22.08 286.68, 76.51 -65.58, -25.0 in-in in 9.908 Saltbr-in 2.7554 HRD-in -73.03, -50.17 73.65, 0.94 in-in-out SNCiio in-out ActLoopNT-in 2.816 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -94.54, -38.19 APE9-dihe-na -68.42, 157.58 APE8-dihe-in -54.06, 126.74 APE8-rot-in 311.62 APE67-dihe-in -64.0, -16.82 -59.31, -46.71 APE12-dist-out 14.394 APE11-dist-in 11.0564 APE10-dist-in 6.9158 APE9-dist-in 4.287 None None CME161 XRAY 1.603 0.176 0.22 A 368.0 337.0 6 31 31 0 [[25, 313]] 1.0 8aog Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G8XA P28482 11 357 360.0 EQT:403,EQT:404 Allosteric,Type1 Inactive DFGin 6.9288 16.2202 BLAminus -127.0, 171.04 70.33, 87.86 -101.76, 19.42 286.15, 72.76 -67.01, -25.23 out-in out 10.0852 Saltbr-in 3.0522 HRD-in -69.17, -52.59 71.2, 7.28 in-in-out SNCiio in-out ActLoopNT-in 2.7992 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -94.81, 149.77 APE9-dihe-na 65.15, 178.01 APE8-dihe-in -91.48, 142.7 APE8-rot-in 291.51 APE67-dihe-in -61.14, -21.62 -49.32, -50.91 APE12-dist-in 13.4913 APE11-dist-in 11.4897 APE10-dist-out 8.911 APE9-dist-in 3.2276 None None CME161 XRAY 1.76 0.167 0.217 A 368.0 339.0 0 31 31 0 [[25, 313]] 1.0 6g8x Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6QA1A P28482 11 358 360.0 HVK:402,HVK:403,HVK:404,HVK:405,HVK:406,HVK:407,HVK:408 Allosteric,Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 6.7607 16.7277 BLAminus -135.55, 177.67 62.97, 80.07 -93.23, 24.97 286.56, 81.05 -59.92, -35.8 out-out out 10.1503 Saltbr-out 5.5045 HRD-in -69.93, -53.53 76.59, 4.02 out-in-out SNCoio in-out ActLoopNT-in 2.8001 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -107.89, -31.2 APE9-dihe-na -62.32, 155.7 APE8-dihe-in -48.95, 124.85 APE8-rot-in 312.15 APE67-dihe-in -64.53, -16.99 -56.95, -46.9 APE12-dist-out 14.383 APE11-dist-in 10.9687 APE10-dist-in 7.3149 APE9-dist-in 4.1957 None None CME161 XRAY 1.58 0.168 0.203 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 6qa1 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6QA4A P28482 11 357 360.0 HRZ:402,HRZ:403,HRZ:404,HRZ:405 Allosteric,Type1,Allosteric,Type3 Inactive DFGin 6.8578 16.3027 BLAminus -132.02, 179.08 62.09, 80.41 -97.94, 19.4 285.68, 75.69 -60.47, -28.93 out-out out 10.2657 Saltbr-out 7.1395 HRD-in -74.15, -50.25 74.19, 4.76 out-in-out SNCoio in-out ActLoopNT-in 2.7537 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -59.52, 147.4 APE9-dihe-na 65.62, 177.04 APE8-dihe-in -90.04, 144.19 APE8-rot-in 287.38 APE67-dihe-in -65.83, -19.24 -48.33, -51.06 APE12-dist-in 13.2476 APE11-dist-in 11.3163 APE10-dist-out 8.6837 APE9-dist-in 3.033 None None CME161 XRAY 1.6 0.176 0.215 A 368.0 337.0 2 31 31 0 [[25, 313]] 1.0 6qa4 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4IZ7A P28482 11 360 360.0 No_ligand No_ligand Inactive DFGin 6.7791 16.3853 BLAminus -132.97, -178.72 63.66, 80.29 -101.39, 20.27 283.23, 71.58 -61.04, -25.26 out-in out 10.3002 Saltbr-in 2.6775 HRD-in -78.11, -51.56 79.12, -6.4 in-in-out SNCiio in-out ActLoopNT-in 2.7898 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iiio APE10-dihe-na -85.94, 135.52 APE9-dihe-na -28.41, -102.11 APE8-dihe-in -66.17, 105.49 APE8-rot-in 328.49 APE67-dihe-in -65.55, -19.28 -51.85, -44.19 APE12-dist-in 12.3652 APE11-dist-in 11.8165 APE10-dist-in 5.9776 APE9-dist-out 6.7345 None None None XRAY 1.8 0.187 0.222 A 356.0 344.0 6 31 25 6 [[25, 313]] 1.0 4iz7 Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4IZ7C P28482 11 359 360.0 No_ligand No_ligand Inactive DFGin 6.8265 16.3954 BLAminus -132.72, -179.02 62.3, 79.44 -102.34, 20.3 285.22, 75.68 -54.93, -29.16 in-in in 9.9694 Saltbr-in 2.6399 HRD-in -74.05, -47.12 72.94, -4.3 in-in-out SNCiio in-out ActLoopNT-in 2.8605 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioo APE10-dihe-na -129.15, 147.4 APE9-dihe-na -70.28, -33.83 APE8-dihe-in -115.27, 111.37 APE8-rot-in 304.75 APE67-dihe-in -74.12, -3.61 -106.1, -7.47 APE12-dist-out 6.7811 APE11-dist-in 10.8335 APE10-dist-out 8.9253 APE9-dist-out 11.3512 None None None XRAY 1.8 0.187 0.222 C 356.0 340.0 9 31 22 9 [[25, 313]] 1.0 4iz7 Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4IZAA P28482 11 358 360.0 No_ligand No_ligand Inactive DFGin 6.7716 16.4482 BLAminus -129.85, -176.34 68.35, 73.87 -101.91, 18.02 280.1, 70.06 -62.61, -26.2 in-in in 9.9823 Saltbr-in 2.5085 HRD-in -67.1, -53.14 77.26, -1.94 in-in-out SNCiio in-out ActLoopNT-in 2.8209 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iooo APE10-dihe-na -129.09, 28.01 APE9-dihe-na -88.83, 7.82 APE8-dihe-out -120.34, 16.45 APE8-rot-in 313.77 APE67-dihe-in -71.68, -14.26 -48.45, -41.92 APE12-dist-in 11.2457 APE11-dist-out 7.4141 APE10-dist-out 12.8508 APE9-dist-out 9.9508 None TPO185,PTR187 TPO185,PTR187 XRAY 1.93 0.199 0.243 A 356.0 348.0 0 31 31 0 [[25, 313]] 1.0 4iza Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4IZAC P28482 11 358 360.0 No_ligand No_ligand Inactive DFGin 6.8504 16.4972 BLAminus -135.43, -175.74 69.86, 75.04 -101.18, 17.42 285.53, 76.16 -59.4, -25.37 out-none out 10.3448 Saltbr-none 999.0 HRD-in -67.56, -54.71 80.03, -9.06 none-in-out SNCnio in-out ActLoopNT-in 2.6429 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 126.48 APE8-rot-out 60.76 APE67-dihe-in -68.72, -16.52 -103.69, -14.86 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None TPO185,PTR187 TPO185,PTR187 XRAY 1.93 0.199 0.243 C 356.0 335.0 13 31 18 13 [[25, 313]] 1.0 4iza Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6Q7SA P28482 11 356 360.0 No_ligand No_ligand Inactive DFGin 6.871 16.4429 BLAminus -135.86, 178.78 64.53, 68.35 -89.93, 21.9 286.65, 77.96 -65.54, -26.51 out-out out 10.5018 Saltbr-out 6.046 HRD-in -71.72, -53.2 75.58, -1.79 out-in-out SNCoio in-out ActLoopNT-in 2.7387 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -104.24, -26.98 APE9-dihe-na -73.73, 160.8 APE8-dihe-in -64.49, 127.62 APE8-rot-in 314.27 APE67-dihe-in -62.97, -18.93 -54.09, -51.47 APE12-dist-out 14.2732 APE11-dist-in 10.9146 APE10-dist-in 7.0371 APE9-dist-in 4.3815 None None CME161 XRAY 1.73 0.186 0.24 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 6q7s Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6QA3A P28482 8 357 360.0 No_ligand No_ligand Inactive DFGin 6.7494 16.3488 BLAminus -133.97, 178.79 67.84, 69.02 -94.99, 25.64 290.82, 79.28 -65.46, -30.48 out-out out 10.4148 Saltbr-out 5.0254 HRD-in -72.38, -51.15 75.41, 2.05 out-in-out SNCoio in-out ActLoopNT-in 2.8304 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -89.93, -44.85 APE9-dihe-na -63.79, 161.45 APE8-dihe-in -63.48, 128.31 APE8-rot-in 312.79 APE67-dihe-in -66.51, -17.59 -56.23, -48.93 APE12-dist-out 14.0338 APE11-dist-in 10.7858 APE10-dist-in 6.456 APE9-dist-in 4.2118 None None CME161 XRAY 1.57 0.173 0.217 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 6qa3 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP2B P28482 12 357 360.0 No_ligand No_ligand Inactive DFGin 6.8869 16.0169 BLAminus -129.43, -178.45 61.61, 82.07 -103.18, 25.26 281.28, 72.06 -66.08, -26.0 in-in in 9.5302 Saltbr-in 3.519 HRD-in -78.87, -43.35 76.42, -19.49 in-in-out SNCiio in-out ActLoopNT-in 2.8623 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -170.24, 153.12 APE9-dihe-na -111.49, 162.96 APE8-dihe-in -53.17, 118.09 APE8-rot-in 309.96 APE67-dihe-in -60.93, -24.17 -46.56, -46.97 APE12-dist-in 10.876 APE11-dist-in 10.5581 APE10-dist-out 9.6191 APE9-dist-in 4.625 None None NEP125 XRAY 2.23 0.186 0.234 B 369.0 330.0 13 31 28 3 [[25, 313]] 1.0 4qp2 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7E73A P28482 11 357 360.0 No_ligand No_ligand Inactive DFGin 6.7923 16.3827 BLAminus -133.88, -176.67 61.49, 70.96 -87.72, 26.95 288.47, 77.24 -65.94, -21.97 out-out out 10.3623 Saltbr-out 5.6801 HRD-in -67.61, -54.59 76.14, -4.09 out-in-out SNCoio in-out ActLoopNT-in 2.8632 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -85.25, -42.65 APE9-dihe-na -64.83, 162.37 APE8-dihe-in -61.56, 126.65 APE8-rot-in 317.52 APE67-dihe-in -56.38, -21.26 -52.8, -49.77 APE12-dist-out 14.0621 APE11-dist-in 11.0447 APE10-dist-in 6.9322 APE9-dist-in 4.5385 Y36H None None XRAY 2.28 0.184 0.239 A 363.0 347.0 0 31 31 0 [[25, 313]] 1.0 7e73 Homo sapiens CMGC_MAPK1_HUMAN CMGC 7.1e-85 290.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7E75A P28482 10 358 360.0 No_ligand No_ligand Inactive DFGin 6.8391 16.4398 BLAminus -129.94, 175.45 60.3, 73.29 -83.12, 28.79 286.11, 74.5 -66.51, -28.06 out-in out 10.0044 Saltbr-in 3.0244 HRD-in -70.35, -52.87 70.62, 5.79 in-in-out SNCiio in-out ActLoopNT-in 2.8305 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -89.48, -40.38 APE9-dihe-na -62.25, 159.89 APE8-dihe-in -57.08, 131.43 APE8-rot-in 306.44 APE67-dihe-in -67.44, -16.31 -58.81, -44.53 APE12-dist-out 14.6831 APE11-dist-in 10.9658 APE10-dist-in 6.9231 APE9-dist-in 4.2797 G37C None None XRAY 2.481 0.184 0.266 A 363.0 349.0 0 31 31 0 [[25, 313]] 1.0 7e75 Homo sapiens CMGC_MAPK1_HUMAN CMGC 6.1e-85 291.0 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6D5YA P28482 13 357 360.0 No_ligand No_ligand Inactive DFGin 6.8579 15.5428 BLAminus -137.43, 179.95 53.71, 80.86 -100.16, 31.66 285.48, 74.31 -66.48, -38.27 in-out in 9.7266 Saltbr-out 5.958 HRD-in -69.56, -40.53 68.01, -18.75 out-in-out SNCoio in-out ActLoopNT-in 2.7783 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -140.18, 152.7 APE9-dihe-na -62.43, -38.47 APE8-dihe-in -149.63, 148.06 APE8-rot-out 181.82 APE67-dihe-in -68.03, -22.26 -116.51, 12.14 APE12-dist-in 8.1783 APE11-dist-in 11.6247 APE10-dist-out 9.0194 APE9-dist-out 11.3758 G169D None None XRAY 2.86 0.222 0.272 A 348.0 337.0 8 31 23 8 [[25, 313]] 1.0 6d5y Homo sapiens CMGC_MAPK1_HUMAN CMGC 4.6e-84 288.1 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 1PMEA P28482 16 360 360.0 SB2:1001 Type1 Inactive DFGin 6.765 15.5071 BLAminus -135.95, -171.93 64.64, 69.47 -97.54, 30.49 287.85, 71.25 -67.06, -32.75 out-in out 10.0024 Saltbr-in 2.7294 HRD-in -72.65, -45.23 68.62, -0.37 in-in-out SNCiio in-out ActLoopNT-in 2.8378 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -84.16, -42.57 APE9-dihe-na -67.3, 161.57 APE8-dihe-in -53.65, 117.23 APE8-rot-in 314.74 APE67-dihe-in -59.87, -19.34 -44.9, -50.43 APE12-dist-out 14.2826 APE11-dist-in 10.9202 APE10-dist-in 6.4927 APE9-dist-in 4.4944 I103L,Q105T,D106H,E109G,T110A None CME161 XRAY 2.0 0.212 0.273 A 380.0 334.0 3 31 31 0 [[25, 313]] 1.0 1pme Homo sapiens CMGC_MAPK1_HUMAN CMGC 2.9e-85 292.1 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6DMGA P28482 11 357 360.0 EK6:60407 Type1 Inactive DFGin 6.9203 15.5663 BLAminus -133.07, 178.36 60.69, 88.76 -105.82, 29.69 284.69, 69.92 -65.09, -32.16 in-in in 9.4717 Saltbr-in 2.6027 HRD-in -78.24, -51.26 73.1, 7.74 in-in-out SNCiio in-out ActLoopNT-in 2.7427 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.82, -45.49 APE9-dihe-na -55.71, 164.7 APE8-dihe-in -60.78, 135.16 APE8-rot-in 310.53 APE67-dihe-in -57.54, -17.33 -63.43, -50.83 APE12-dist-out 14.5009 APE11-dist-in 11.1823 APE10-dist-in 7.1809 APE9-dist-in 4.2649 None None CME161 XRAY 2.2 0.189 0.236 A 347.0 347.0 0 31 31 0 [[25, 313]] 1.0 6dmg Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.1e-86 293.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4XJ0A P28482 12 360 360.0 41B:401 Type1 Inactive DFGin 6.9253 15.9026 BLAminus -128.72, 178.82 60.25, 84.81 -99.58, 30.32 286.89, 68.04 -63.8, -36.34 in-in in 9.338 Saltbr-in 2.8027 HRD-in -71.71, -51.71 75.23, -2.58 in-in-out SNCiio in-out ActLoopNT-in 2.8054 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -96.68, -131.27 APE9-dihe-na -62.56, 169.56 APE8-dihe-in -72.46, 124.06 APE8-rot-in 293.95 APE67-dihe-in -61.54, -21.14 -31.5, -51.99 APE12-dist-in 8.838 APE11-dist-out 7.7911 APE10-dist-in 7.8669 APE9-dist-in 3.1529 None None NEP125 XRAY 2.58 0.21 0.244 A 349.0 346.0 1 31 31 0 [[25, 313]] 1.0 4xj0 Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.2e-86 293.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4XJ0B P28482 12 357 360.0 41B:401 Type1 Inactive DFGin 6.897 15.908 BLAminus -132.79, 176.01 57.28, 85.46 -101.01, 27.5 284.74, 71.93 -64.54, -32.65 in-in in 9.016 Saltbr-in 2.7424 HRD-in -73.78, -49.99 71.73, 4.29 in-in-out SNCiio in-out ActLoopNT-in 2.7122 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -89.81, -86.54 APE9-dihe-na -108.42, 172.18 APE8-dihe-in -68.23, 129.82 APE8-rot-in 294.66 APE67-dihe-in -55.14, -20.59 -34.58, -62.67 APE12-dist-in 8.6723 APE11-dist-out 7.6116 APE10-dist-in 7.8493 APE9-dist-in 3.3305 None None NEP125 XRAY 2.58 0.21 0.244 B 349.0 339.0 7 31 31 0 [[25, 313]] 1.0 4xj0 Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.2e-86 293.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8ZJVA P28482 10 358 360.0 5ID:401 Type1 Inactive DFGin 6.9106 15.0826 BLAminus -132.32, -178.04 60.39, 69.81 -88.48, 24.49 282.54, 65.61 -59.28, -29.83 in-out in 9.7237 Saltbr-out 3.8504 HRD-in -83.31, -48.81 74.28, 2.88 out-in-in SNCoii in-in ActLoopNT-in 2.7229 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.6, -35.66 APE9-dihe-na -57.94, 156.55 APE8-dihe-in -58.22, 132.29 APE8-rot-in 307.39 APE67-dihe-in -64.79, -16.64 -58.91, -47.39 APE12-dist-in 13.8364 APE11-dist-in 10.9358 APE10-dist-in 7.141 APE9-dist-in 4.3818 None None None XRAY 1.8 0.192 0.22 A 351.0 349.0 0 31 31 0 [[25, 313]] 1.0 8zjv Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.4e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5K4IA P28482 9 358 360.0 6QB:401 Type1 Inactive DFGin 6.9676 15.5827 BLAminus -128.06, 179.26 60.38, 84.38 -100.87, 21.25 280.37, 70.75 -56.14, -35.33 in-in in 9.1488 Saltbr-in 2.6594 HRD-in -74.77, -46.47 73.04, -3.13 in-in-out SNCiio in-out ActLoopNT-in 2.8063 ActLoopCT-out nonTYR APEdihe_aanio APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 29.58 APE8-rot-in 317.14 APE67-dihe-out -63.26, -26.15 54.49, -60.77 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.76 0.183 0.232 A 352.0 336.0 14 31 17 14 [[25, 313]] 1.0 5k4i Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.5e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 3SA0A P28482 4 360 360.0 NRA:361 Type1 Inactive DFGin 6.8096 16.4185 BLAminus -128.15, 173.53 68.16, 82.33 -100.92, 24.65 284.58, 80.45 -66.15, -21.66 out-in out 10.1959 Saltbr-in 3.3429 HRD-in -73.67, -49.24 75.15, -0.79 in-in-out SNCiio in-out ActLoopNT-in 2.8208 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.56, -33.19 APE9-dihe-na -68.73, 157.0 APE8-dihe-in -51.65, 125.57 APE8-rot-in 308.33 APE67-dihe-in -66.34, -15.84 -52.86, -49.01 APE12-dist-out 14.256 APE11-dist-in 10.9844 APE10-dist-in 6.9235 APE9-dist-in 4.3125 None None CME161,CME166,CME254 XRAY 1.595 0.166 0.2 A 360.0 357.0 0 31 31 0 [[25, 313]] 1.0 3sa0 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FUXA P28482 11 357 360.0 E75:60401 Type1 Inactive DFGin 6.7827 16.3268 BLAminus -131.98, 173.23 64.18, 92.42 -107.28, 29.09 287.18, 73.2 -62.92, -25.19 out-out out 10.4355 Saltbr-out 4.0828 HRD-in -68.65, -47.69 68.98, -0.58 out-in-out SNCoio in-out ActLoopNT-in 2.8678 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.33, -33.1 APE9-dihe-na -65.65, 153.7 APE8-dihe-in -49.24, 122.29 APE8-rot-in 318.08 APE67-dihe-in -61.5, -20.64 -47.87, -51.2 APE12-dist-out 14.3562 APE11-dist-in 10.9667 APE10-dist-in 6.8625 APE9-dist-in 4.4037 None None CME161 XRAY 2.2 0.189 0.223 A 360.0 343.0 0 31 31 0 [[25, 313]] 1.0 4fux Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FUYA P28482 11 358 360.0 EK2:60401 Type1 Inactive DFGin 6.6881 16.2544 BLAminus -130.4, 175.2 67.86, 86.39 -101.47, 25.35 286.95, 80.76 -58.55, -28.93 out-out out 10.0232 Saltbr-out 3.7822 HRD-in -74.01, -47.63 67.29, 0.8 out-in-out SNCoio in-out ActLoopNT-in 2.7848 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -89.43, -38.85 APE9-dihe-na -63.21, 157.09 APE8-dihe-in -50.29, 121.79 APE8-rot-in 314.4 APE67-dihe-in -61.79, -22.74 -48.0, -50.77 APE12-dist-out 14.1648 APE11-dist-in 10.9 APE10-dist-in 6.7545 APE9-dist-in 4.3457 None None CME161,CME166,CME254 XRAY 2.0 0.19 0.217 A 360.0 332.0 6 31 31 0 [[25, 313]] 1.0 4fuy Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FV0A P28482 11 358 360.0 EK3:60401 Type1 Inactive DFGin 6.7016 16.5897 BLAminus -135.37, 177.45 64.31, 87.1 -103.53, 24.78 286.26, 83.38 -61.65, -32.0 out-out out 10.4133 Saltbr-out 5.0914 HRD-in -69.19, -51.99 72.25, -1.4 out-in-out SNCoio in-out ActLoopNT-in 2.7327 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.88, -31.2 APE9-dihe-na -67.61, 162.64 APE8-dihe-in -58.38, 116.74 APE8-rot-in 312.14 APE67-dihe-in -58.34, -24.84 -48.98, -48.23 APE12-dist-out 14.2516 APE11-dist-in 10.8272 APE10-dist-in 6.9036 APE9-dist-in 4.5028 None None CME161,CME166,CME254 XRAY 2.1 0.176 0.221 A 360.0 344.0 0 31 31 0 [[25, 313]] 1.0 4fv0 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FV1A P28482 11 356 360.0 EK4:60401 Type1 Inactive DFGin 6.882 15.7881 BLAminus -128.65, -179.92 58.68, 89.27 -103.93, 26.87 282.58, 70.61 -62.53, -30.27 in-in in 9.6093 Saltbr-in 2.6382 HRD-in -70.74, -50.58 70.91, 3.53 in-in-out SNCiio in-out ActLoopNT-in 2.8164 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.48, -42.28 APE9-dihe-na -56.85, 152.08 APE8-dihe-in -48.18, 121.04 APE8-rot-in 315.61 APE67-dihe-in -60.27, -19.49 -50.25, -54.02 APE12-dist-out 14.5786 APE11-dist-in 11.2844 APE10-dist-in 7.3103 APE9-dist-in 4.3863 None None CME161 XRAY 1.99 0.182 0.225 A 360.0 343.0 0 31 31 0 [[25, 313]] 1.0 4fv1 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FV2A P28482 11 357 360.0 EK5:60401 Type1 Inactive DFGin 6.9282 15.5747 BLAminus -125.87, 177.7 60.4, 91.72 -106.05, 22.47 282.22, 72.48 -61.11, -31.38 in-in in 9.6139 Saltbr-in 2.6501 HRD-in -73.27, -50.24 71.89, 6.48 in-in-out SNCiio in-out ActLoopNT-in 2.8463 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.13, -41.13 APE9-dihe-na -56.8, 151.84 APE8-dihe-in -51.06, 121.97 APE8-rot-in 312.92 APE67-dihe-in -60.07, -18.44 -50.57, -54.42 APE12-dist-out 14.5319 APE11-dist-in 11.2599 APE10-dist-in 7.1809 APE9-dist-in 4.2534 None None CME161 XRAY 2.0 0.181 0.211 A 360.0 345.0 0 31 31 0 [[25, 313]] 1.0 4fv2 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FV3A P28482 11 357 360.0 EK6:60401 Type1 Inactive DFGin 6.9204 15.5434 BLAminus -128.41, 176.81 62.18, 92.27 -108.69, 28.96 282.46, 73.53 -64.35, -33.27 in-in in 9.4958 Saltbr-in 2.5965 HRD-in -72.39, -48.68 68.34, 4.53 in-in-out SNCiio in-out ActLoopNT-in 2.7992 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.4, -45.32 APE9-dihe-na -52.9, 153.24 APE8-dihe-in -50.54, 121.86 APE8-rot-in 314.89 APE67-dihe-in -54.54, -21.53 -50.33, -56.04 APE12-dist-out 14.5535 APE11-dist-in 11.0404 APE10-dist-in 7.1133 APE9-dist-in 4.3325 None None CME161 XRAY 2.2 0.194 0.236 A 360.0 347.0 0 31 31 0 [[25, 313]] 1.0 4fv3 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FV7A P28482 11 358 360.0 E94:60401 Type1 Inactive DFGin 6.7505 15.2985 BLAminus -131.38, 170.76 61.08, 92.51 -98.87, 27.02 282.81, 83.46 -61.79, -27.94 in-in in 9.3476 Saltbr-in 2.7299 HRD-in -71.48, -49.08 72.62, -5.62 in-in-out SNCiio in-out ActLoopNT-in 2.8176 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -84.4, -37.98 APE9-dihe-na -73.15, 158.52 APE8-dihe-in -50.31, 121.34 APE8-rot-in 315.03 APE67-dihe-in -59.69, -17.96 -45.2, -57.15 APE12-dist-out 14.146 APE11-dist-in 10.9845 APE10-dist-in 6.5536 APE9-dist-in 4.424 None None CME161,CME254 XRAY 1.9 0.184 0.208 A 360.0 344.0 0 31 31 0 [[25, 313]] 1.0 4fv7 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4G6NA P28482 11 358 360.0 EK0:60401 Type1 Inactive DFGin 6.8123 16.1652 BLAminus -131.25, -179.75 63.09, 82.17 -100.91, 24.89 285.94, 74.26 -63.08, -24.54 out-out out 10.274 Saltbr-out 4.4022 HRD-in -69.01, -50.25 70.2, 2.18 out-in-out SNCoio in-out ActLoopNT-in 2.8284 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -87.99, -49.88 APE9-dihe-na -51.77, 152.56 APE8-dihe-in -49.69, 121.96 APE8-rot-in 318.5 APE67-dihe-in -61.88, -19.83 -49.94, -50.95 APE12-dist-out 14.4497 APE11-dist-in 11.0166 APE10-dist-in 6.8261 APE9-dist-in 4.3111 None None CME161 XRAY 2.0 0.189 0.225 A 360.0 342.0 0 31 31 0 [[25, 313]] 1.0 4g6n Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4G6OA P28482 11 357 360.0 E28:60401 Type1 Inactive DFGin 6.8676 15.7672 BLAminus -132.32, 171.16 68.07, 92.69 -108.93, 25.2 285.69, 75.37 -63.05, -29.38 in-in in 9.8751 Saltbr-in 2.6091 HRD-in -73.49, -49.08 71.04, 5.76 in-in-out SNCiio in-out ActLoopNT-in 2.87 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -94.79, -39.82 APE9-dihe-na -57.3, 151.65 APE8-dihe-in -47.93, 121.54 APE8-rot-in 314.11 APE67-dihe-in -59.01, -19.0 -49.51, -52.55 APE12-dist-out 14.5085 APE11-dist-in 11.0806 APE10-dist-in 7.0605 APE9-dist-in 4.3423 None None CME161,CME254 XRAY 2.2 0.182 0.226 A 360.0 341.0 2 31 31 0 [[25, 313]] 1.0 4g6o Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4N0SA P28482 6 357 360.0 DHC:401 Type1 Inactive DFGin 6.8229 16.2444 BLAminus -128.69, 171.78 67.96, 85.58 -103.3, 23.69 285.91, 81.72 -64.56, -25.09 in-in in 9.7872 Saltbr-in 2.5676 HRD-in -74.15, -53.22 76.21, 1.31 in-in-out SNCiio in-out ActLoopNT-in 2.8026 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.19, -38.38 APE9-dihe-na -61.29, 155.86 APE8-dihe-in -51.16, 125.28 APE8-rot-in 310.76 APE67-dihe-in -61.05, -17.42 -53.27, -52.48 APE12-dist-out 14.3991 APE11-dist-in 11.1017 APE10-dist-in 7.0324 APE9-dist-in 4.2673 None None CME65,CME161,CME166,CME254 XRAY 1.799 0.156 0.189 A 360.0 352.0 0 31 31 0 [[25, 313]] 1.0 4n0s Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4ZXTA P28482 7 357 360.0 CAQ:401 Type1 Inactive DFGin 6.7009 16.3505 BLAminus -130.15, 172.75 68.13, 81.0 -97.66, 27.23 286.93, 81.73 -67.09, -23.48 in-in in 9.8851 Saltbr-in 3.0666 HRD-in -74.52, -53.3 74.8, -0.36 in-in-out SNCiio in-out ActLoopNT-in 2.7631 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -90.15, -37.46 APE9-dihe-na -64.75, 157.78 APE8-dihe-in -51.68, 126.67 APE8-rot-in 310.04 APE67-dihe-in -65.57, -16.47 -57.13, -47.67 APE12-dist-out 14.2841 APE11-dist-in 10.9411 APE10-dist-in 6.8704 APE9-dist-in 4.342 None None CME161,CME166,CME254 XRAY 2.0 0.155 0.183 A 360.0 351.0 0 31 31 0 [[25, 313]] 1.0 4zxt Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5LCKA P28482 11 357 360.0 6TT:405 Type1 Inactive DFGin 6.833 16.3617 BLAminus -131.32, 176.11 61.41, 85.37 -98.86, 24.24 288.14, 70.28 -64.0, -28.03 out-in out 10.1133 Saltbr-in 3.1384 HRD-in -71.06, -50.82 73.25, -0.73 in-in-out SNCiio in-out ActLoopNT-in 2.7479 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.15, -42.62 APE9-dihe-na -61.49, 157.76 APE8-dihe-in -63.32, 126.75 APE8-rot-in 312.53 APE67-dihe-in -62.37, -18.92 -55.45, -50.31 APE12-dist-out 14.5531 APE11-dist-in 11.1154 APE10-dist-in 6.948 APE9-dist-in 4.2426 None None CME127,CME161 XRAY 1.89 0.166 0.212 A 360.0 347.0 0 31 31 0 [[25, 313]] 1.0 5lck Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5LCJA P28482 11 357 360.0 6TS:401 Type1 Inactive DFGin 6.8566 16.3984 BLAminus -133.84, 179.61 58.41, 84.49 -97.23, 19.15 287.32, 73.24 -57.76, -29.68 in-in in 9.7875 Saltbr-in 2.7292 HRD-in -70.75, -48.77 69.94, 3.32 in-in-out SNCiio in-out ActLoopNT-in 2.7887 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.15, -43.92 APE9-dihe-na -60.16, 161.13 APE8-dihe-in -68.17, 127.19 APE8-rot-in 313.62 APE67-dihe-in -59.22, -20.63 -49.4, -54.81 APE12-dist-out 14.526 APE11-dist-in 11.1857 APE10-dist-in 6.9331 APE9-dist-in 4.0678 None None CME161 XRAY 1.78 0.165 0.212 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 5lcj Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G91A P28482 8 357 360.0 EQW:403 Type1 Inactive DFGin 6.833 16.2128 BLAminus -129.12, 173.4 66.9, 86.58 -102.5, 23.7 285.8, 73.37 -66.86, -28.43 in-in in 9.8484 Saltbr-in 2.7089 HRD-in -71.91, -52.82 75.11, 8.05 in-in-out SNCiio in-out ActLoopNT-in 2.7922 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -94.42, -34.41 APE9-dihe-na -72.71, 166.97 APE8-dihe-in -70.09, 128.2 APE8-rot-in 306.07 APE67-dihe-in -65.08, -18.81 -53.56, -48.36 APE12-dist-out 14.5035 APE11-dist-in 11.1854 APE10-dist-in 6.9758 APE9-dist-in 4.1663 None None CME161 XRAY 1.8 0.169 0.22 A 368.0 345.0 0 31 31 0 [[25, 313]] 1.0 6g91 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G92A P28482 8 357 360.0 ERZ:404 Type1 Inactive DFGin 6.7948 16.0099 BLAminus -129.08, 178.13 66.15, 83.92 -102.64, 21.66 286.21, 77.45 -65.22, -27.45 out-in out 10.0858 Saltbr-in 2.9853 HRD-in -67.98, -54.58 72.32, 6.81 in-in-out SNCiio in-out ActLoopNT-in 2.7273 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.78, -39.98 APE9-dihe-na -69.58, 164.27 APE8-dihe-in -62.75, 127.33 APE8-rot-in 313.21 APE67-dihe-in -68.69, -16.41 -55.06, -45.14 APE12-dist-out 14.6322 APE11-dist-in 11.199 APE10-dist-in 7.0093 APE9-dist-in 4.3113 None None CME161 XRAY 1.99 0.167 0.227 A 368.0 344.0 0 31 31 0 [[25, 313]] 1.0 6g92 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G93A P28482 11 357 360.0 EU2:406 Type1 Inactive DFGin 6.861 15.416 BLAminus -128.45, 175.41 69.18, 82.85 -99.46, 27.42 281.6, 77.67 -68.16, -23.82 in-in in 9.5572 Saltbr-in 2.714 HRD-in -71.99, -50.41 73.92, 2.92 in-in-out SNCiio in-out ActLoopNT-in 2.8277 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -88.24, -36.27 APE9-dihe-na -73.61, 165.11 APE8-dihe-in -63.24, 129.83 APE8-rot-in 308.21 APE67-dihe-in -64.06, -18.71 -58.14, -46.82 APE12-dist-out 14.494 APE11-dist-in 11.2615 APE10-dist-in 6.8314 APE9-dist-in 4.2491 None None CME161 XRAY 1.67 0.173 0.213 A 368.0 344.0 0 31 31 0 [[25, 313]] 1.0 6g93 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G97A P28482 11 357 360.0 EQZ:407 Type1 Inactive DFGin 6.7002 14.938 BLAminus -125.84, -179.56 61.12, 78.12 -92.48, 23.09 286.69, 78.92 -62.72, -27.99 in-in in 9.1734 Saltbr-in 2.7708 HRD-in -75.99, -51.88 76.88, 3.3 in-in-out SNCiio in-out ActLoopNT-in 2.7191 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.17, -31.33 APE9-dihe-na -65.13, 158.09 APE8-dihe-in -55.46, 126.0 APE8-rot-in 305.91 APE67-dihe-in -65.76, -19.34 -57.25, -45.19 APE12-dist-out 14.4133 APE11-dist-in 11.1867 APE10-dist-in 7.4123 APE9-dist-in 4.4174 None None CME161 XRAY 1.9 0.164 0.223 A 368.0 345.0 0 31 31 0 [[25, 313]] 1.0 6g97 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G9AA P28482 8 357 360.0 ESQ:404 Type1 Inactive DFGin 6.809 15.7486 BLAminus -133.55, 175.54 70.21, 80.12 -98.94, 35.97 283.37, 75.29 -74.82, -27.7 in-in in 9.5939 Saltbr-in 2.7217 HRD-in -73.03, -53.33 75.02, 8.47 in-in-out SNCiio in-out ActLoopNT-in 2.7794 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.87, -26.44 APE9-dihe-na -77.35, 160.11 APE8-dihe-in -55.77, 127.56 APE8-rot-in 307.22 APE67-dihe-in -65.89, -20.78 -58.13, -41.92 APE12-dist-out 14.379 APE11-dist-in 11.1123 APE10-dist-in 6.9367 APE9-dist-in 4.2263 None None CME161 XRAY 1.91 0.182 0.25 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 6g9a Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G9MA P28482 11 356 360.0 ESW:404 Type1 Inactive DFGin 6.7926 16.1252 BLAminus -130.4, 178.4 64.83, 86.11 -105.98, 21.48 280.05, 78.72 -67.32, -25.7 in-in in 9.8972 Saltbr-in 2.6957 HRD-in -72.12, -52.61 74.73, 0.78 in-in-out SNCiio in-out ActLoopNT-in 2.8267 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -89.95, -41.88 APE9-dihe-na -68.93, 161.07 APE8-dihe-in -54.0, 127.27 APE8-rot-in 310.85 APE67-dihe-in -66.49, -16.25 -58.19, -47.4 APE12-dist-out 14.6239 APE11-dist-in 11.2459 APE10-dist-in 7.1339 APE9-dist-in 4.4408 None None CME161 XRAY 1.86 0.16 0.206 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 6g9m Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6GDQA P28482 10 357 360.0 EVK:407 Type1 Inactive DFGin 6.8906 15.0859 BLAminus -121.36, 176.04 66.05, 86.82 -103.12, 27.78 283.55, 74.24 -70.02, -23.75 in-in in 9.4567 Saltbr-in 2.7494 HRD-in -75.22, -50.5 75.66, 3.76 in-in-out SNCiio in-out ActLoopNT-in 2.8668 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.91, -37.76 APE9-dihe-na -66.69, 161.06 APE8-dihe-in -59.55, 129.43 APE8-rot-in 308.79 APE67-dihe-in -60.08, -19.42 -59.96, -47.92 APE12-dist-out 14.6395 APE11-dist-in 11.2664 APE10-dist-in 7.105 APE9-dist-in 4.266 None None CME161 XRAY 1.86 0.183 0.226 A 368.0 340.0 0 31 31 0 [[25, 313]] 1.0 6gdq Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6GJBA P28482 8 357 360.0 F0H:406 Type1 Inactive DFGin 6.8368 16.293 BLAminus -126.98, 179.07 63.86, 85.36 -103.53, 21.34 281.07, 75.2 -67.74, -24.46 in-in in 9.8373 Saltbr-in 2.7014 HRD-in -74.2, -47.41 71.12, 5.16 in-in-out SNCiio in-out ActLoopNT-in 2.8482 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.51, -37.65 APE9-dihe-na -68.71, 167.6 APE8-dihe-in -73.02, 127.9 APE8-rot-in 308.91 APE67-dihe-in -62.78, -17.85 -56.2, -48.74 APE12-dist-out 14.6185 APE11-dist-in 11.2287 APE10-dist-in 7.1226 APE9-dist-in 4.3012 None None CME161 XRAY 1.82 0.166 0.206 A 368.0 348.0 0 31 31 0 [[25, 313]] 1.0 6gjb Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6Q7KA P28482 8 357 360.0 2AI:402 Type1 Inactive DFGin 6.632 16.3302 BLAminus -133.8, 178.83 63.78, 79.31 -92.04, 27.48 287.22, 82.56 -61.45, -34.33 out-out out 10.1956 Saltbr-out 6.1197 HRD-in -75.78, -49.45 68.06, 4.85 out-in-in SNCoii in-in ActLoopNT-in 2.7578 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -100.75, -11.98 APE9-dihe-na -70.17, 165.14 APE8-dihe-in -64.85, 129.41 APE8-rot-in 320.27 APE67-dihe-in -61.77, -17.43 -50.8, -55.55 APE12-dist-in 13.7347 APE11-dist-in 10.5228 APE10-dist-in 7.4955 APE9-dist-in 4.4751 None None CME161 XRAY 1.84 0.214 0.263 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 6q7k Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6QAWA P28482 11 357 360.0 HVE:402 Type1 Inactive DFGin 6.8864 16.4273 BLAminus -130.86, 178.03 65.32, 83.3 -102.82, 19.54 284.49, 77.56 -61.13, -26.51 out-in out 10.5368 Saltbr-in 2.7518 HRD-in -70.95, -54.2 74.28, 5.68 in-in-out SNCiio in-out ActLoopNT-in 2.738 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.95, -38.46 APE9-dihe-na -64.02, 161.82 APE8-dihe-in -69.45, 129.99 APE8-rot-in 309.38 APE67-dihe-in -65.8, -13.89 -55.83, -49.38 APE12-dist-out 14.4256 APE11-dist-in 11.2095 APE10-dist-in 7.0542 APE9-dist-in 4.168 None None CME127,CME161 XRAY 1.84 0.176 0.221 A 368.0 338.0 0 31 31 0 [[25, 313]] 1.0 6qaw Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6RQ4A P28482 19 357 360.0 KE8:402 Type1 Inactive DFGin 6.8474 15.9698 BLAminus -128.54, 178.3 64.79, 78.45 -100.16, 26.93 286.26, 70.97 -73.15, -19.61 out-in out 10.0359 Saltbr-in 2.8212 HRD-in -71.88, -50.45 75.67, 1.9 in-in-out SNCiio in-out ActLoopNT-in 2.8269 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -101.27, -34.28 APE9-dihe-na -68.61, 157.72 APE8-dihe-in -49.0, 128.91 APE8-rot-in 310.29 APE67-dihe-in -57.21, -20.43 -61.38, -50.93 APE12-dist-out 14.3023 APE11-dist-in 11.0143 APE10-dist-in 7.0236 APE9-dist-in 4.3086 None None CME161 XRAY 1.96 0.178 0.232 A 368.0 332.0 0 31 31 0 [[25, 313]] 1.0 6rq4 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7NR3A P28482 11 356 360.0 UO5:403 Type1 Inactive DFGin 6.9245 16.0971 BLAminus -130.06, 178.7 64.56, 85.28 -102.95, 23.54 283.45, 75.36 -71.31, -27.37 in-in in 9.5862 Saltbr-in 2.6938 HRD-in -69.68, -49.47 70.56, 8.46 in-in-out SNCiio in-out ActLoopNT-in 2.8179 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.95, -33.96 APE9-dihe-na -70.24, 164.84 APE8-dihe-in -69.84, 133.41 APE8-rot-in 308.31 APE67-dihe-in -61.04, -17.03 -62.39, -48.06 APE12-dist-out 14.5567 APE11-dist-in 11.1809 APE10-dist-in 7.047 APE9-dist-in 4.183 None None CME161 XRAY 1.897 0.186 0.236 A 368.0 337.0 0 31 31 0 [[25, 313]] 1.0 7nr3 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AO2A P28482 13 357 360.0 NXI:403 Type1 Inactive DFGin 6.9737 16.0872 BLAminus -127.0, 175.32 65.42, 90.96 -103.32, 20.32 287.87, 77.93 -68.75, -24.84 out-in out 10.1829 Saltbr-in 2.5466 HRD-in -71.83, -49.59 70.69, 9.06 in-in-out SNCiio in-out ActLoopNT-in 2.8169 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -120.49, 145.2 APE9-dihe-na 68.78, 172.76 APE8-dihe-in -86.31, 144.9 APE8-rot-in 292.42 APE67-dihe-in -64.12, -21.4 -51.53, -50.75 APE12-dist-in 13.5871 APE11-dist-in 11.3878 APE10-dist-out 8.9602 APE9-dist-in 3.2191 None None CME161 XRAY 1.796 0.172 0.219 A 368.0 341.0 0 31 31 0 [[25, 313]] 1.0 8ao2 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AO3A P28482 11 357 360.0 NYX:403 Type1 Inactive DFGin 6.9386 16.0931 BLAminus -132.25, 175.07 64.16, 87.67 -100.11, 18.89 284.96, 74.3 -61.41, -29.58 out-in out 10.3479 Saltbr-in 2.8108 HRD-in -70.24, -51.94 74.04, 4.8 in-in-out SNCiio in-out ActLoopNT-in 2.8188 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.46, -38.87 APE9-dihe-na -66.82, 162.01 APE8-dihe-in -63.69, 123.72 APE8-rot-in 311.7 APE67-dihe-in -65.35, -15.16 -54.01, -48.2 APE12-dist-out 14.5798 APE11-dist-in 11.2081 APE10-dist-in 7.1645 APE9-dist-in 4.2345 None None CME127,CME161 XRAY 1.778 0.171 0.209 A 368.0 339.0 0 31 31 0 [[25, 313]] 1.0 8ao3 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AO4A P28482 11 357 360.0 N8U:404 Type1 Inactive DFGin 6.9526 16.1498 BLAminus -127.45, 178.22 65.53, 84.35 -97.67, 21.24 287.61, 71.09 -68.52, -22.12 out-in out 10.2614 Saltbr-in 2.6533 HRD-in -73.4, -50.97 71.89, 8.15 in-in-out SNCiio in-out ActLoopNT-in 2.7639 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.16, -34.31 APE9-dihe-na -67.02, 162.42 APE8-dihe-in -69.78, 130.09 APE8-rot-in 307.95 APE67-dihe-in -63.57, -16.58 -55.88, -49.8 APE12-dist-out 14.5358 APE11-dist-in 11.2093 APE10-dist-in 7.2444 APE9-dist-in 4.1632 None None CME127,CME161 XRAY 1.825 0.176 0.222 A 368.0 339.0 0 31 31 0 [[25, 313]] 1.0 8ao4 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AO5A P28482 15 356 360.0 N6K:404 Type1 Inactive DFGin 6.7799 16.2441 BLAminus -133.08, 178.76 65.02, 81.87 -99.24, 26.92 285.8, 73.59 -67.79, -20.29 out-in out 10.3488 Saltbr-in 2.677 HRD-in -70.06, -53.33 72.08, 4.5 in-in-out SNCiio in-out ActLoopNT-in 2.7825 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -90.81, -42.59 APE9-dihe-na -66.23, 157.78 APE8-dihe-in -48.65, 124.73 APE8-rot-in 313.04 APE67-dihe-in -61.1, -18.16 -56.92, -48.04 APE12-dist-out 14.5387 APE11-dist-in 11.1572 APE10-dist-in 7.0251 APE9-dist-in 4.3235 None None CME161 XRAY 1.595 0.182 0.214 A 368.0 330.0 3 31 31 0 [[25, 313]] 1.0 8ao5 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AO6A P28482 11 356 360.0 N9F:406 Type1 Inactive DFGin 6.7709 16.337 BLAminus -129.81, 177.88 71.62, 78.81 -103.22, 23.44 283.23, 73.97 -64.0, -29.38 out-in out 10.3714 Saltbr-in 2.597 HRD-in -72.45, -50.74 72.14, 4.83 in-in-out SNCiio in-out ActLoopNT-in 2.7853 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.92, -36.24 APE9-dihe-na -66.98, 156.39 APE8-dihe-in -51.35, 125.27 APE8-rot-in 311.93 APE67-dihe-in -64.42, -17.18 -56.32, -47.54 APE12-dist-out 14.4141 APE11-dist-in 11.1069 APE10-dist-in 7.1029 APE9-dist-in 4.2638 None None CME127,CME161 XRAY 1.811 0.175 0.222 A 368.0 338.0 0 31 31 0 [[25, 313]] 1.0 8ao6 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AO7A P28482 11 356 360.0 N3X:405 Type1 Inactive DFGin 6.7103 16.4925 BLAminus -130.29, 175.2 63.99, 83.71 -99.06, 20.5 284.28, 78.44 -62.72, -26.91 out-in out 10.0995 Saltbr-in 2.8326 HRD-in -69.87, -51.12 72.22, 5.22 in-in-out SNCiio in-out ActLoopNT-in 2.8002 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.64, -38.24 APE9-dihe-na -67.32, 159.83 APE8-dihe-in -59.65, 128.33 APE8-rot-in 309.86 APE67-dihe-in -62.17, -17.84 -57.44, -48.08 APE12-dist-out 14.6174 APE11-dist-in 11.203 APE10-dist-in 7.1777 APE9-dist-in 4.241 None None CME161 XRAY 1.61 0.18 0.213 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 8ao7 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AO8A P28482 11 356 360.0 N5U:404 Type1 Inactive DFGin 6.8404 16.2541 BLAminus -124.47, 159.94 66.97, 91.28 -101.17, 23.74 286.55, 70.97 -69.86, -26.55 out-in out 10.186 Saltbr-in 2.777 HRD-in -73.33, -50.93 73.69, 3.86 in-in-out SNCiio in-out ActLoopNT-in 2.844 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.88, -36.2 APE9-dihe-na -74.28, 161.44 APE8-dihe-in -60.31, 128.44 APE8-rot-in 313.77 APE67-dihe-in -60.66, -18.48 -57.92, -51.15 APE12-dist-out 14.5766 APE11-dist-in 11.2776 APE10-dist-in 6.9297 APE9-dist-in 4.2436 None None CME161 XRAY 1.697 0.174 0.211 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 8ao8 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AO9A P28482 11 356 360.0 N4F:406 Type1 Inactive DFGin 6.837 16.4502 BLAminus -129.5, 178.83 61.88, 81.37 -96.97, 21.21 286.14, 78.83 -59.7, -30.7 out-out out 10.3006 Saltbr-out 3.7652 HRD-in -72.95, -49.65 72.84, 3.98 out-in-out SNCoio in-out ActLoopNT-in 2.8539 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.06, -44.4 APE9-dihe-na -60.28, 156.59 APE8-dihe-in -55.09, 130.24 APE8-rot-in 307.62 APE67-dihe-in -64.58, -17.09 -62.44, -44.52 APE12-dist-out 14.2701 APE11-dist-in 10.9807 APE10-dist-in 6.7892 APE9-dist-in 4.2298 None None CME161 XRAY 1.624 0.184 0.232 A 368.0 338.0 2 31 31 0 [[25, 313]] 1.0 8ao9 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AOBA P28482 18 356 360.0 NB3:403 Type1 Inactive DFGin 6.7516 16.1645 BLAminus -128.36, 178.48 65.28, 86.43 -100.71, 25.07 286.34, 74.77 -65.61, -24.15 out-in out 10.1005 Saltbr-in 2.983 HRD-in -71.47, -50.97 71.51, 5.75 in-in-out SNCiio in-out ActLoopNT-in 2.8095 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -94.09, -39.14 APE9-dihe-na -64.67, 155.77 APE8-dihe-in -48.32, 123.77 APE8-rot-in 313.88 APE67-dihe-in -63.98, -17.45 -56.05, -46.79 APE12-dist-out 14.4705 APE11-dist-in 11.1245 APE10-dist-in 7.1389 APE9-dist-in 4.3045 None None CME161 XRAY 1.623 0.19 0.219 A 368.0 321.0 9 31 31 0 [[25, 313]] 1.0 8aob Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AOCA P28482 11 356 360.0 N3O:404 Type1 Inactive DFGin 6.8078 16.5641 BLAminus -134.22, 176.12 61.31, 83.78 -95.87, 22.58 287.89, 72.74 -61.25, -30.2 out-in out 10.0676 Saltbr-in 2.9852 HRD-in -68.58, -52.47 76.18, -0.03 in-in-out SNCiio in-out ActLoopNT-in 2.805 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.04, -39.01 APE9-dihe-na -66.54, 160.54 APE8-dihe-in -60.46, 127.52 APE8-rot-in 307.48 APE67-dihe-in -65.27, -16.19 -57.34, -47.83 APE12-dist-out 14.4223 APE11-dist-in 11.1654 APE10-dist-in 6.9827 APE9-dist-in 4.2503 None None CME161,CME254 XRAY 1.62 0.18 0.217 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 8aoc Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AOEA P28482 11 356 360.0 N6U:404 Type1 Inactive DFGin 6.8456 16.2819 BLAminus -132.37, -178.87 58.37, 82.96 -99.09, 25.19 287.98, 69.56 -66.93, -25.42 out-in out 10.3904 Saltbr-in 2.8304 HRD-in -67.93, -53.19 72.31, 4.69 in-in-out SNCiio in-out ActLoopNT-in 2.8513 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -92.48, -40.8 APE9-dihe-na -62.56, 159.15 APE8-dihe-in -56.43, 129.3 APE8-rot-in 309.56 APE67-dihe-in -62.42, -18.54 -61.43, -45.9 APE12-dist-out 14.4693 APE11-dist-in 11.1035 APE10-dist-in 7.0696 APE9-dist-in 4.286 None None CME161 XRAY 1.687 0.188 0.23 A 368.0 337.0 9 31 31 0 [[25, 313]] 1.0 8aoe Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AOFA P28482 11 356 360.0 N4U:404 Type1 Inactive DFGin 6.7815 16.4051 BLAminus -132.51, 174.94 63.69, 84.19 -96.49, 22.47 287.54, 73.86 -62.42, -28.19 out-in out 10.0276 Saltbr-in 2.694 HRD-in -71.23, -49.41 73.98, 2.59 in-in-out SNCiio in-out ActLoopNT-in 2.8233 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.09, -36.54 APE9-dihe-na -68.25, 159.72 APE8-dihe-in -59.27, 130.06 APE8-rot-in 309.47 APE67-dihe-in -63.72, -17.26 -60.16, -47.14 APE12-dist-out 14.2985 APE11-dist-in 11.0495 APE10-dist-in 6.8308 APE9-dist-in 4.213 None None CME161 XRAY 1.615 0.176 0.218 A 368.0 341.0 5 31 31 0 [[25, 313]] 1.0 8aof Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AOJA P28482 10 356 360.0 N8L:407 Type1 Inactive DFGin 6.8369 16.082 BLAminus -127.69, 169.46 70.05, 82.88 -97.45, 30.61 290.22, 67.33 -76.11, -5.52 in-in in 9.8535 Saltbr-in 2.8552 HRD-in -74.88, -52.62 76.87, 1.14 in-in-out SNCiio in-out ActLoopNT-in 2.8419 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -90.16, -32.1 APE9-dihe-na -79.1, 161.85 APE8-dihe-in -53.19, 128.47 APE8-rot-in 308.92 APE67-dihe-in -65.83, -16.72 -55.59, -45.91 APE12-dist-out 14.2864 APE11-dist-in 11.0395 APE10-dist-in 6.668 APE9-dist-in 4.4124 None None CME161 XRAY 1.12 0.18 0.203 A 368.0 340.0 0 31 31 0 [[25, 313]] 1.0 8aoj Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 3W55A P28482 11 357 360.0 1FM:401 Type1 Inactive DFGin 6.8453 15.3111 BLAminus -114.5, 159.86 66.42, 121.73 -134.68, 25.56 281.37, 73.75 -67.05, -27.15 in-in in 9.7658 Saltbr-in 3.3276 HRD-in -73.73, -41.19 69.72, -22.0 in-in-out SNCiio in-out ActLoopNT-in 3.2448 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_nnoo APE10-dihe-na 999.0, 108.71 APE9-dihe-na 148.35, -177.22 APE8-dihe-out -15.28, -98.64 APE8-rot-out 164.29 APE67-dihe-out -92.01, -3.61 134.93, -62.27 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 10.0062 APE9-dist-out 7.3671 None None None XRAY 3.0 0.277 0.281 A 368.0 335.0 12 31 19 12 [[25, 313]] 1.0 3w55 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5AX3A P28482 10 358 360.0 5ID:60401 Type1 Inactive DFGin 7.0825 16.4278 BLAminus -127.71, -158.49 57.95, 57.37 -96.01, 22.02 283.93, 97.26 -69.96, -43.04 out-out out 10.3799 Saltbr-out 5.4612 HRD-in -80.67, -26.64 62.8, -46.45 out-in-out SNCoio in-out ActLoopNT-in 2.6796 ActLoopCT-out nonTYR APEdihe_aanii APEdist_iion APE10-dihe-na -119.6, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 86.51 APE8-rot-in 343.49 APE67-dihe-in -91.22, -8.7 -96.21, 42.35 APE12-dist-in 8.4834 APE11-dist-in 9.8124 APE10-dist-out 9.5116 APE9-dist-none 999.0 None None None XRAY 2.984 0.239 0.285 A 368.0 329.0 20 31 22 9 [[25, 313]] 1.0 5ax3 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7W5OA P28482 11 360 360.0 5ID:401 Type1 Inactive DFGin 6.7259 16.0736 BLAminus -134.06, -178.68 57.89, 83.45 -97.58, 26.47 285.78, 74.05 -62.2, -23.74 in-out in 9.5977 Saltbr-out 3.6644 HRD-in -64.25, -57.62 81.95, -6.27 out-in-out SNCoio in-out ActLoopNT-in 2.8418 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -125.26, 105.21 APE9-dihe-na 77.53, 139.94 APE8-dihe-in -62.13, 139.76 APE8-rot-in 304.97 APE67-dihe-in -67.0, -21.21 -48.23, -45.39 APE12-dist-in 8.898 APE11-dist-out 7.5203 APE10-dist-in 7.6672 APE9-dist-in 3.0549 None None NEP125 XRAY 2.35 0.228 0.279 A 368.0 350.0 0 31 31 0 [[25, 313]] 1.0 7w5o Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7XC1B P28482 12 357 360.0 5ID:402 Type1 Inactive DFGin 6.7495 15.8478 BLAminus -136.86, 178.87 56.25, 81.89 -92.76, 18.78 288.3, 68.54 -60.11, -21.88 in-in in 9.1742 Saltbr-in 3.022 HRD-in -76.63, -53.91 78.34, 9.0 in-in-out SNCiio in-out ActLoopNT-in 2.7077 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -112.15, 106.32 APE9-dihe-na 73.8, 141.03 APE8-dihe-in -61.74, 138.85 APE8-rot-in 297.46 APE67-dihe-in -56.69, -24.12 -44.69, -58.48 APE12-dist-in 8.3558 APE11-dist-out 7.5573 APE10-dist-in 7.8496 APE9-dist-in 3.0354 None None NEP125 XRAY 2.09 0.232 0.271 B 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 7xc1 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4O6EA P28482 13 357 360.0 2SH:401 Type1 Inactive DFGin 6.9793 16.0643 BLAminus -129.07, 179.57 59.4, 82.21 -100.26, 25.66 282.82, 72.21 -58.83, -35.99 in-in in 9.3168 Saltbr-in 2.7894 HRD-in -71.69, -45.65 70.14, -2.53 in-in-out SNCiio in-out ActLoopNT-in 2.7687 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 128.7 APE9-dihe-na -71.46, -32.14 APE8-dihe-in -151.2, 142.21 APE8-rot-out 186.25 APE67-dihe-in -63.05, -17.07 -112.45, 9.16 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.3381 APE9-dist-out 11.0791 None None None XRAY 1.95 0.223 0.223 A 368.0 328.0 14 31 20 11 [[25, 313]] 1.0 4o6e Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP1A P28482 12 360 360.0 EMU:401 Type1 Inactive DFGin 6.9626 16.2282 BLAminus -131.47, 175.74 65.18, 79.32 -100.68, 29.14 286.53, 66.72 -63.4, -33.69 out-out out 10.0382 Saltbr-out 3.9837 HRD-in -69.26, -48.17 74.21, -5.61 out-in-out SNCoio in-out ActLoopNT-in 2.698 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -61.27, 168.08 APE9-dihe-na -77.59, 175.7 APE8-dihe-in -63.31, 118.92 APE8-rot-in 314.45 APE67-dihe-in -61.09, -22.53 -42.79, -50.97 APE12-dist-in 9.9501 APE11-dist-out 7.4936 APE10-dist-out 9.8647 APE9-dist-in 4.1107 None None NEP125 XRAY 2.7 0.206 0.255 A 369.0 343.0 0 31 31 0 [[25, 313]] 1.0 4qp1 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP1B P28482 12 357 360.0 EMU:401 Type1 Inactive DFGin 6.6903 15.7386 BLAminus -124.13, -176.14 57.57, 85.87 -105.59, 31.14 285.08, 67.96 -70.32, -24.06 in-out in 9.5661 Saltbr-out 3.9932 HRD-in -75.52, -44.16 67.6, 8.01 out-in-out SNCoio in-out ActLoopNT-in 2.7216 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -127.44, 102.2 APE9-dihe-na 68.05, 148.06 APE8-dihe-in -61.45, 136.17 APE8-rot-in 303.04 APE67-dihe-in -60.44, -20.34 -48.19, -50.72 APE12-dist-in 8.9194 APE11-dist-in 8.2741 APE10-dist-out 8.2601 APE9-dist-in 3.1613 None None NEP125 XRAY 2.7 0.206 0.255 B 369.0 344.0 2 31 31 0 [[25, 313]] 1.0 4qp1 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP2A P28482 12 360 360.0 36R:401 Type1 Inactive DFGin 7.0169 16.3573 BLAminus -132.76, -176.99 60.37, 76.22 -97.44, 23.32 283.67, 70.96 -63.1, -20.06 in-in in 9.9583 Saltbr-in 3.2131 HRD-in -76.56, -48.46 78.73, -15.62 in-in-out SNCiio in-out ActLoopNT-in 2.6898 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -88.71, 155.85 APE9-dihe-na -97.01, 160.1 APE8-dihe-in -54.37, 118.09 APE8-rot-in 313.36 APE67-dihe-in -58.35, -23.39 -45.67, -50.34 APE12-dist-none 999.0 APE11-dist-out 7.8812 APE10-dist-out 9.9482 APE9-dist-in 4.4264 None None NEP125 XRAY 2.23 0.186 0.234 A 369.0 337.0 9 31 25 6 [[25, 313]] 1.0 4qp2 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP3A P28482 12 360 360.0 36Q:401 Type1 Inactive DFGin 6.8589 15.8504 BLAminus -127.22, -175.68 56.17, 83.19 -104.18, 33.87 282.73, 66.64 -69.96, -32.58 in-in in 9.4451 Saltbr-in 3.3006 HRD-in -82.76, -44.96 76.07, -9.05 in-in-out SNCiio in-out ActLoopNT-in 2.7052 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nioi APE10-dihe-na -121.34, 159.1 APE9-dihe-na -79.4, 177.88 APE8-dihe-in -61.83, 123.04 APE8-rot-in 305.81 APE67-dihe-in -62.86, -21.0 -53.45, -47.23 APE12-dist-none 999.0 APE11-dist-in 8.2622 APE10-dist-out 9.9697 APE9-dist-in 4.301 None None NEP125 XRAY 2.599 0.224 0.268 A 369.0 340.0 9 31 25 6 [[25, 313]] 1.0 4qp3 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP3B P28482 12 357 360.0 36Q:401 Type1 Inactive DFGin 6.793 15.7599 BLAminus -126.47, -174.48 52.27, 87.61 -103.66, 26.42 284.37, 73.41 -63.65, -24.28 in-in in 9.6052 Saltbr-in 3.1992 HRD-in -81.82, -47.44 72.19, -4.98 in-in-out SNCiio in-out ActLoopNT-in 2.6859 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na 63.14, -151.19 APE9-dihe-na -73.19, 165.34 APE8-dihe-in -60.84, 129.71 APE8-rot-in 299.14 APE67-dihe-in -62.09, -19.8 -45.81, -49.44 APE12-dist-in 9.7944 APE11-dist-in 8.512 APE10-dist-out 8.3522 APE9-dist-in 3.4733 None None NEP125 XRAY 2.599 0.224 0.268 B 369.0 332.0 11 31 28 3 [[25, 313]] 1.0 4qp3 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP4A P28482 13 357 360.0 36O:401 Type1 Inactive DFGin 6.8241 15.938 BLAminus -125.3, 167.13 64.24, 90.48 -108.14, 22.59 286.42, 75.22 -64.25, -26.15 in-out in 8.9178 Saltbr-out 6.0785 HRD-in -71.48, -47.45 75.24, -9.93 out-in-out SNCoio in-out ActLoopNT-in 2.9796 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -129.97, 154.52 APE9-dihe-na -62.24, -33.02 APE8-dihe-in -154.8, 145.42 APE8-rot-out 182.51 APE67-dihe-in -65.24, -7.26 -115.09, 10.29 APE12-dist-in 9.2228 APE11-dist-in 12.394 APE10-dist-out 9.1008 APE9-dist-out 11.038 None None None XRAY 2.2 0.189 0.235 A 369.0 337.0 8 31 23 8 [[25, 313]] 1.0 4qp4 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP4B P28482 12 357 360.0 36O:401 Type1 Inactive DFGin 6.9518 16.3408 BLAminus -131.86, 174.32 59.22, 89.07 -106.19, 23.73 288.41, 79.68 -67.52, -18.25 in-out in 9.2153 Saltbr-out 4.4894 HRD-in -76.21, -48.26 75.02, -6.33 out-in-out SNCoio in-out ActLoopNT-in 2.8132 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -122.9, 128.44 APE9-dihe-na -79.48, -89.06 APE8-dihe-in -75.04, 141.7 APE8-rot-in 317.37 APE67-dihe-in -69.0, -20.44 -124.09, -5.27 APE12-dist-in 9.1797 APE11-dist-in 12.4613 APE10-dist-out 11.2141 APE9-dist-out 10.244 None None None XRAY 2.2 0.189 0.235 B 369.0 335.0 11 31 20 11 [[25, 313]] 1.0 4qp4 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP6A P28482 12 360 360.0 36N:401 Type1 Inactive DFGin 6.8649 16.0487 BLAminus -134.19, 177.24 61.24, 85.87 -106.12, 27.42 286.39, 74.31 -64.08, -29.18 in-in in 9.7186 Saltbr-in 3.1724 HRD-in -73.59, -43.93 70.49, -12.41 in-in-out SNCiio in-out ActLoopNT-in 2.6757 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -93.66, 171.23 APE9-dihe-na -81.86, -178.38 APE8-dihe-in -66.96, 124.64 APE8-rot-in 304.43 APE67-dihe-in -65.66, -28.46 -50.73, -45.49 APE12-dist-none 999.0 APE11-dist-out 7.8432 APE10-dist-out 9.8747 APE9-dist-in 4.1913 None None NEP125 XRAY 3.1 0.215 0.251 A 369.0 340.0 9 31 25 6 [[25, 313]] 1.0 4qp6 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP6B P28482 12 357 360.0 36N:401 Type1 Inactive DFGin 6.7833 15.6243 BLAminus -135.41, -176.58 58.97, 85.85 -108.91, 30.4 287.99, 68.55 -72.19, -15.06 in-in in 9.6133 Saltbr-in 3.4142 HRD-in -81.72, -40.85 62.99, 11.61 in-in-out SNCiio in-out ActLoopNT-in 2.729 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -112.85, 150.4 APE9-dihe-na -66.19, 155.78 APE8-dihe-in -60.29, 123.23 APE8-rot-in 306.84 APE67-dihe-in -59.17, -27.19 -47.63, -50.44 APE12-dist-in 9.0613 APE11-dist-out 6.8478 APE10-dist-out 9.6916 APE9-dist-in 3.6394 None None NEP125 XRAY 3.1 0.215 0.251 B 369.0 335.0 11 31 28 3 [[25, 313]] 1.0 4qp6 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP7A P28482 13 357 360.0 363:401 Type1 Inactive DFGin 6.8497 15.7484 BLAminus -132.24, 176.87 62.32, 84.56 -106.17, 23.49 288.44, 72.17 -65.38, -26.87 in-in in 8.7515 Saltbr-in 3.3931 HRD-in -78.16, -47.13 71.74, -6.4 in-in-out SNCiio in-out ActLoopNT-in 2.8517 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -125.07, 152.43 APE9-dihe-na -64.16, -36.92 APE8-dihe-in -151.45, 144.61 APE8-rot-out 177.7 APE67-dihe-in -68.24, -8.08 -110.93, 12.21 APE12-dist-in 8.8566 APE11-dist-in 12.196 APE10-dist-out 9.2472 APE9-dist-out 10.8468 None None None XRAY 2.249 0.208 0.243 A 369.0 337.0 8 31 23 8 [[25, 313]] 1.0 4qp7 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP7B P28482 12 357 360.0 363:401 Type1 Inactive DFGin 7.1055 16.6106 BLAminus -135.43, 179.06 61.46, 85.59 -106.29, 24.23 287.16, 78.5 -67.15, -18.05 in-out in 9.8132 Saltbr-out 4.1382 HRD-in -76.72, -48.85 72.61, -2.86 out-in-out SNCoio in-out ActLoopNT-in 2.6685 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -114.32, 148.28 APE9-dihe-na -105.7, -8.19 APE8-dihe-in -170.3, 125.09 APE8-rot-in 288.27 APE67-dihe-in -58.36, -23.63 -104.22, -4.05 APE12-dist-in 9.4012 APE11-dist-in 12.4348 APE10-dist-out 10.8813 APE9-dist-out 10.2343 None None None XRAY 2.249 0.208 0.243 B 369.0 335.0 11 31 20 11 [[25, 313]] 1.0 4qp7 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP8A P28482 12 357 360.0 362:401 Type1 Inactive DFGin 7.1206 16.0234 BLAminus -138.97, 178.67 58.83, 81.69 -100.67, 28.37 284.73, 74.19 -64.65, -23.89 in-in in 9.1643 Saltbr-in 2.4899 HRD-in -76.49, -45.63 73.25, -7.2 in-in-out SNCiio in-out ActLoopNT-in 2.6578 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -115.06, 140.25 APE9-dihe-na -81.99, -90.41 APE8-dihe-in -85.54, 134.34 APE8-rot-in 298.33 APE67-dihe-in -61.64, -19.92 -107.69, -3.1 APE12-dist-in 9.7117 APE11-dist-in 12.1893 APE10-dist-out 11.013 APE9-dist-out 10.0751 None None None XRAY 2.446 0.206 0.249 A 369.0 335.0 11 31 20 11 [[25, 313]] 1.0 4qp8 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP8B P28482 13 357 360.0 362:401 Type1 Inactive DFGin 6.976 15.4619 BLAminus -132.6, -178.43 57.44, 85.0 -105.8, 25.19 285.22, 65.23 -60.86, -34.2 in-in in 8.8253 Saltbr-in 3.0801 HRD-in -81.03, -47.24 74.23, -7.22 in-in-out SNCiio in-out ActLoopNT-in 2.841 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -127.99, 150.46 APE9-dihe-na -61.94, -34.3 APE8-dihe-in -151.1, 145.37 APE8-rot-out 182.62 APE67-dihe-in -74.4, -5.5 -115.62, 16.65 APE12-dist-in 9.3382 APE11-dist-in 12.306 APE10-dist-out 9.2112 APE9-dist-out 10.8388 None None None XRAY 2.446 0.206 0.249 B 369.0 337.0 8 31 23 8 [[25, 313]] 1.0 4qp8 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QP9A P28482 13 357 360.0 35X:401 Type1 Inactive DFGin 6.9376 15.3413 BLAminus -130.0, -173.82 68.16, 72.94 -105.1, 24.85 282.89, 75.71 -66.76, -30.66 in-in in 9.3786 Saltbr-in 2.5118 HRD-in -80.31, -47.56 78.27, -7.94 in-in-out SNCiio in-out ActLoopNT-in 2.699 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -135.53, 155.6 APE9-dihe-na -68.22, -35.06 APE8-dihe-in -149.12, 139.63 APE8-rot-out 179.85 APE67-dihe-in -66.79, -15.72 -108.34, 3.59 APE12-dist-in 9.614 APE11-dist-in 13.1378 APE10-dist-out 9.8164 APE9-dist-out 11.7397 None None None XRAY 2.001 0.186 0.227 A 369.0 335.0 8 31 23 8 [[25, 313]] 1.0 4qp9 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QPAA P28482 12 357 360.0 35W:60401 Type1 Inactive DFGin 6.6307 15.6681 BLAminus -136.5, -177.35 57.93, 81.68 -102.89, 29.52 286.81, 65.92 -68.51, -24.46 in-out in 9.4927 Saltbr-out 3.8625 HRD-in -77.16, -44.3 70.0, -5.49 out-in-out SNCoio in-out ActLoopNT-in 2.6862 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -133.82, -177.08 APE9-dihe-na -115.74, 137.26 APE8-dihe-in -54.82, 121.13 APE8-rot-in 306.72 APE67-dihe-in -60.3, -21.81 -45.58, -51.1 APE12-dist-in 10.2377 APE11-dist-in 9.4922 APE10-dist-out 8.8648 APE9-dist-in 3.8432 None None NEP125 XRAY 2.85 0.214 0.253 A 369.0 332.0 11 31 28 3 [[25, 313]] 1.0 4qpa Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QPAB P28482 12 360 360.0 35W:60401 Type1 Inactive DFGin 6.8708 16.2178 BLAminus -133.06, 176.84 64.38, 82.12 -104.1, 27.34 284.96, 71.65 -64.94, -31.45 out-in out 10.0662 Saltbr-in 3.3168 HRD-in -76.47, -42.35 70.97, -15.95 in-in-out SNCiio in-out ActLoopNT-in 2.71 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -93.45, -162.2 APE9-dihe-na -84.91, -167.23 APE8-dihe-in -75.25, 118.31 APE8-rot-in 309.12 APE67-dihe-in -62.58, -28.37 -42.27, -50.62 APE12-dist-in 11.0287 APE11-dist-in 8.7807 APE10-dist-out 8.9155 APE9-dist-in 4.3175 None None NEP125 XRAY 2.85 0.214 0.253 B 369.0 346.0 2 31 29 2 [[25, 313]] 1.0 4qpa Homo sapiens CMGC_MAPK1_HUMAN CMGC 1e-85 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4ZZMA P28482 11 355 360.0 CQ6:1357 Type1 Inactive DFGin 7.0304 16.3552 BLAminus -126.63, -175.69 56.15, 85.43 -102.35, 20.51 285.78, 80.49 -63.28, -29.01 in-out in 9.8603 Saltbr-out 4.5679 HRD-in -72.39, -53.13 71.33, 3.98 out-in-out SNCoio in-out ActLoopNT-in 2.8685 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -110.95, 138.07 APE9-dihe-na 65.0, -177.02 APE8-dihe-in -89.16, 134.03 APE8-rot-in 293.15 APE67-dihe-in -60.55, -17.17 -32.84, -60.53 APE12-dist-in 13.2012 APE11-dist-in 11.2942 APE10-dist-out 8.9595 APE9-dist-in 3.1317 None None CME161 XRAY 1.89 0.21 0.254 A 350.0 345.0 0 31 31 0 [[25, 313]] 1.0 4zzm Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.2e-85 293.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4ZZNA P28482 11 355 360.0 CQ8:61355 Type1 Inactive DFGin 6.7305 16.385 BLAminus -125.62, 167.09 59.43, 95.37 -102.42, 18.52 285.84, 80.13 -61.06, -26.76 in-in in 9.3407 Saltbr-in 2.8014 HRD-in -67.38, -51.21 72.41, 6.03 in-in-out SNCiio in-out ActLoopNT-in 2.8141 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -89.29, -45.49 APE9-dihe-na -50.96, 152.72 APE8-dihe-in -55.84, 123.26 APE8-rot-in 314.25 APE67-dihe-in -59.18, -22.99 -48.37, -54.07 APE12-dist-out 14.4485 APE11-dist-in 11.2871 APE10-dist-in 7.0346 APE9-dist-in 4.087 None None CME161 XRAY 1.33 0.175 0.202 A 350.0 339.0 0 31 31 0 [[25, 313]] 1.0 4zzn Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.2e-85 293.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4ZZOA P28482 11 355 360.0 CQ3:1357 Type1 Inactive DFGin 6.887 16.2189 BLAminus -131.27, 174.96 60.69, 93.91 -105.67, 18.33 284.84, 78.56 -63.6, -22.53 in-in in 9.1104 Saltbr-in 2.6757 HRD-in -66.92, -50.1 73.58, 2.48 in-in-out SNCiio in-out ActLoopNT-in 2.8175 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -107.77, 141.44 APE9-dihe-na 63.91, 177.13 APE8-dihe-in -84.81, 136.22 APE8-rot-in 291.46 APE67-dihe-in -63.19, -21.52 -37.39, -54.7 APE12-dist-in 13.4742 APE11-dist-in 11.6356 APE10-dist-out 9.0137 APE9-dist-in 3.1946 None None CME161 XRAY 1.63 0.191 0.237 A 350.0 340.0 0 31 31 0 [[25, 313]] 1.0 4zzo Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.2e-85 293.3 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 2OJGA P28482 19 357 360.0 19A:60360 Type1 Inactive DFGin 6.779 15.7199 BLAminus -127.46, 179.27 64.17, 86.16 -104.35, 28.83 283.56, 69.28 -67.52, -27.97 in-in in 9.5989 Saltbr-in 2.6042 HRD-in -75.69, -53.61 79.84, -2.74 in-in-out SNCiio in-out ActLoopNT-in 2.6951 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.83, -40.68 APE9-dihe-na -55.36, 156.37 APE8-dihe-in -56.12, 134.31 APE8-rot-in 307.38 APE67-dihe-in -61.84, -15.71 -62.4, -48.63 APE12-dist-out 14.7058 APE11-dist-in 11.2638 APE10-dist-in 7.3646 APE9-dist-in 4.3678 None None None XRAY 2.0 0.233 0.26 A 380.0 337.0 0 31 31 0 [[25, 313]] 1.0 2ojg Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 2OJIA P28482 15 358 360.0 33A:60360 Type1 Inactive DFGin 6.7854 16.3983 BLAminus -132.53, 175.62 62.73, 87.52 -104.73, 37.95 284.25, 59.44 -73.68, -20.82 out-in out 10.1012 Saltbr-in 3.1148 HRD-in -72.86, -54.76 76.49, 2.85 in-in-out SNCiio in-out ActLoopNT-in 2.8555 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.26, -26.54 APE9-dihe-na -67.43, 166.5 APE8-dihe-in -61.43, 135.98 APE8-rot-in 299.82 APE67-dihe-in -66.79, -11.81 -72.57, -38.73 APE12-dist-out 14.6525 APE11-dist-in 11.2062 APE10-dist-in 7.3794 APE9-dist-in 4.3911 None None None XRAY 2.6 0.239 0.267 A 380.0 344.0 0 31 31 0 [[25, 313]] 1.0 2oji Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 2OJJA P28482 15 358 360.0 82A:60360 Type1 Inactive DFGin 6.9278 15.7087 BLAminus -134.63, 171.22 66.3, 85.66 -103.17, 35.01 286.71, 65.45 -71.35, -20.96 in-in in 9.5705 Saltbr-in 2.5872 HRD-in -72.18, -44.82 72.99, -2.41 in-in-out SNCiio in-out ActLoopNT-in 2.7625 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -117.66, -34.13 APE9-dihe-na -60.97, 166.57 APE8-dihe-in -69.05, 134.04 APE8-rot-in 303.47 APE67-dihe-in -59.58, -20.53 -59.77, -50.51 APE12-dist-out 14.4453 APE11-dist-in 11.1936 APE10-dist-in 7.1623 APE9-dist-in 4.116 None None None XRAY 2.4 0.215 0.268 A 380.0 344.0 0 31 31 0 [[25, 313]] 1.0 2ojj Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 9LNRA P28482 9 358 360.0 A1EKR:401 Type1 Inactive DFGin 6.8939 14.8353 BLAminus -132.98, -174.48 54.93, 86.46 -100.06, 23.76 285.97, 66.46 -61.1, -34.13 in-in in 9.0292 Saltbr-in 2.5011 HRD-in -74.57, -52.5 79.29, -5.96 in-in-out SNCiio in-out ActLoopNT-in 2.7074 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -155.64 APE8-rot-out 57.16 APE67-dihe-in -69.2, -14.2 -106.5, 12.61 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.1 0.213 0.277 A 380.0 333.0 17 31 16 15 [[25, 313]] 1.0 9lnr Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5NGUA P28482 11 355 360.0 8X2:403 Type1 Inactive DFGin 6.8244 15.4125 BLAminus -131.8, 173.94 54.59, 63.73 -75.37, 12.55 291.92, 86.34 -57.76, -29.82 in-in in 9.3443 Saltbr-in 2.5044 HRD-in -69.49, -51.37 67.92, 17.66 in-in-out SNCiio in-out ActLoopNT-in 2.7727 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -117.12, -31.72 APE9-dihe-na -50.59, 143.23 APE8-dihe-in -52.47, 127.91 APE8-rot-in 314.94 APE67-dihe-in -84.77, -26.48 -48.59, -26.11 APE12-dist-out 14.4197 APE11-dist-in 11.354 APE10-dist-in 7.6339 APE9-dist-in 4.0226 None None CME161 XRAY 2.74 0.266 0.262 A 381.0 340.0 0 31 31 0 [[25, 313]] 1.0 5ngu Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5NHFA P28482 12 355 360.0 8X5:402 Type1 Inactive DFGin 6.9779 15.7383 BLAminus -131.22, -177.26 60.47, 71.66 -95.07, 17.48 291.88, 68.57 -59.32, -37.52 in-out in 9.8227 Saltbr-out 4.1383 HRD-in -69.08, -56.17 78.63, -4.25 out-in-out SNCoio in-out ActLoopNT-in 2.6998 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -113.63, -36.25 APE9-dihe-na -59.51, 153.91 APE8-dihe-in -53.09, 125.53 APE8-rot-in 307.89 APE67-dihe-in -66.28, -15.97 -57.32, -40.32 APE12-dist-out 14.2616 APE11-dist-in 11.1646 APE10-dist-in 7.0321 APE9-dist-in 4.1558 None None CME161 XRAY 2.14 0.248 0.259 A 381.0 340.0 0 31 31 0 [[25, 313]] 1.0 5nhf Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5NHHA P28482 11 358 360.0 8XH:404 Type1 Inactive DFGin 6.9774 14.8199 BLAminus -123.6, -173.61 56.59, 82.5 -98.03, 21.32 285.02, 79.79 -59.4, -24.9 in-in in 9.2106 Saltbr-in 2.7434 HRD-in -74.19, -51.04 72.31, 4.45 in-in-out SNCiio in-out ActLoopNT-in 2.7951 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -94.16, -52.11 APE9-dihe-na -51.37, 157.59 APE8-dihe-in -65.96, 124.8 APE8-rot-in 313.27 APE67-dihe-in -57.65, -21.58 -40.05, -64.42 APE12-dist-out 14.4064 APE11-dist-in 11.1634 APE10-dist-in 6.8103 APE9-dist-in 4.039 None None None XRAY 1.94 0.183 0.22 A 381.0 348.0 0 31 31 0 [[25, 313]] 1.0 5nhh Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5NHJA P28482 11 355 360.0 8XE:403 Type1 Inactive DFGin 7.0703 14.9245 BLAminus -129.81, -179.77 60.64, 76.52 -95.64, 20.89 284.82, 79.91 -59.37, -34.53 in-in in 9.2753 Saltbr-in 2.5321 HRD-in -67.69, -55.32 71.57, 12.88 in-in-out SNCiio in-out ActLoopNT-in 2.7635 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -90.43, -16.06 APE9-dihe-na -73.33, 160.47 APE8-dihe-in -60.61, 133.87 APE8-rot-in 319.8 APE67-dihe-in -65.92, -16.91 -61.1, -44.69 APE12-dist-out 14.3741 APE11-dist-in 11.1093 APE10-dist-in 7.1667 APE9-dist-in 4.3832 None None None XRAY 2.12 0.202 0.207 A 381.0 345.0 0 31 31 0 [[25, 313]] 1.0 5nhj Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5NHLA P28482 11 355 360.0 8XB:402 Type1 Inactive DFGin 6.8158 15.2822 BLAminus -139.26, -173.51 58.97, 71.02 -94.26, 20.48 284.18, 78.38 -54.1, -36.53 in-in in 9.6258 Saltbr-in 3.1614 HRD-in -64.32, -47.55 73.98, -3.15 in-in-out SNCiio in-out ActLoopNT-in 2.8784 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.51, -36.44 APE9-dihe-na -58.94, 156.87 APE8-dihe-in -57.88, 132.4 APE8-rot-in 306.9 APE67-dihe-in -55.59, -21.11 -57.75, -53.28 APE12-dist-out 14.1519 APE11-dist-in 10.9351 APE10-dist-in 6.8636 APE9-dist-in 4.3969 None None None XRAY 2.07 0.211 0.237 A 381.0 345.0 0 31 31 0 [[25, 313]] 1.0 5nhl Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5NHOA P28482 11 355 360.0 8XN:402 Type1 Inactive DFGin 6.7748 14.9302 BLAminus -128.12, -172.81 57.57, 69.48 -93.21, 16.81 282.74, 78.43 -59.67, -38.3 in-in in 9.3082 Saltbr-in 2.4319 HRD-in -70.35, -53.92 79.23, -4.46 in-in-out SNCiio in-out ActLoopNT-in 2.9382 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -77.13, -52.3 APE9-dihe-na -46.62, 149.13 APE8-dihe-in -50.41, 119.77 APE8-rot-in 304.89 APE67-dihe-in -57.6, -18.79 -46.37, -52.99 APE12-dist-out 14.5068 APE11-dist-in 11.0345 APE10-dist-in 7.1188 APE9-dist-in 4.4481 None None None XRAY 2.24 0.201 0.231 A 381.0 343.0 0 31 31 0 [[25, 313]] 1.0 5nho Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5NHPA P28482 11 355 360.0 8XK:403 Type1 Inactive DFGin 6.7358 15.287 BLAminus -133.41, 177.47 61.57, 77.45 -96.25, 22.52 284.35, 75.89 -59.57, -36.21 in-in in 9.4483 Saltbr-in 3.0231 HRD-in -65.9, -48.64 69.88, 3.81 in-in-out SNCiio in-out ActLoopNT-in 2.7445 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.85, -37.07 APE9-dihe-na -65.74, 155.72 APE8-dihe-in -47.43, 115.1 APE8-rot-in 316.51 APE67-dihe-in -59.18, -15.78 -43.52, -52.87 APE12-dist-out 14.5075 APE11-dist-in 11.1324 APE10-dist-in 7.1095 APE9-dist-in 4.4778 None None None XRAY 1.99 0.199 0.221 A 381.0 338.0 0 31 31 0 [[25, 313]] 1.0 5nhp Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5NHVA P28482 11 355 360.0 8QB:402 Type1 Inactive DFGin 6.9487 15.3641 BLAminus -123.53, 177.96 58.53, 89.42 -103.15, 22.56 288.99, 74.77 -58.64, -38.74 in-in in 9.121 Saltbr-in 2.7836 HRD-in -72.87, -48.92 68.99, 2.01 in-in-out SNCiio in-out ActLoopNT-in 2.8764 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -87.07, -47.14 APE9-dihe-na -52.95, 153.81 APE8-dihe-in -61.02, 123.38 APE8-rot-in 307.95 APE67-dihe-in -56.45, -21.77 -45.48, -58.17 APE12-dist-out 14.3987 APE11-dist-in 11.3086 APE10-dist-in 6.9029 APE9-dist-in 4.0801 None None None XRAY 2.0 0.186 0.228 A 381.0 345.0 0 31 31 0 [[25, 313]] 1.0 5nhv Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6SLGA P28482 18 356 360.0 LHZ:401 Type1 Inactive DFGin 6.8771 15.8272 BLAminus -132.14, -179.5 65.09, 83.25 -102.36, 23.01 284.81, 73.87 -64.88, -22.82 in-in in 9.9163 Saltbr-in 2.7035 HRD-in -74.6, -50.76 72.67, 6.01 in-in-out SNCiio in-out ActLoopNT-in 2.8059 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.29, -34.93 APE9-dihe-na -64.83, 158.43 APE8-dihe-in -48.5, 123.79 APE8-rot-in 311.17 APE67-dihe-in -63.81, -16.49 -52.51, -50.2 APE12-dist-out 14.3759 APE11-dist-in 11.1095 APE10-dist-in 7.2847 APE9-dist-in 4.3841 None None None XRAY 1.33 0.207 0.228 A 381.0 332.0 0 31 31 0 [[25, 313]] 1.0 6slg Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.6e-85 292.9 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5WP1A P28482 15 357 360.0 B7S:401,BEZ:403 Type1,Allosteric Inactive DFGin 6.8478 16.8208 BLAminus -131.08, 174.79 68.08, 80.16 -96.05, 24.08 289.54, 79.55 -65.36, -26.41 out-out out 10.2828 Saltbr-out 6.6659 HRD-in -74.08, -53.37 76.14, 3.14 out-in-out SNCoio in-out ActLoopNT-in 2.8044 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.04, -37.91 APE9-dihe-na -67.19, 159.66 APE8-dihe-in -53.56, 128.07 APE8-rot-in 309.0 APE67-dihe-in -66.9, -15.26 -56.35, -46.18 APE12-dist-out 14.1878 APE11-dist-in 10.9008 APE10-dist-in 7.0449 APE9-dist-in 4.4209 None None CME127,CME161,CME166 XRAY 1.4 0.142 0.18 A 357.0 343.0 0 31 31 0 [[25, 313]] 1.0 5wp1 Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.9e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6Q7TA P28482 11 356 360.0 HOW:402,HOW:403 Type1,Allosteric Inactive DFGin 6.7308 16.4827 BLAminus -134.88, 178.16 63.34, 76.93 -96.51, 20.6 283.36, 78.59 -63.48, -26.46 in-out in 9.7295 Saltbr-out 5.6666 HRD-in -72.05, -52.36 73.88, 5.86 out-in-out SNCoio in-out ActLoopNT-in 2.8281 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -92.01, -37.19 APE9-dihe-na -68.64, 160.64 APE8-dihe-in -64.39, 130.65 APE8-rot-in 311.37 APE67-dihe-in -64.26, -15.1 -59.16, -48.05 APE12-dist-out 14.1314 APE11-dist-in 10.8768 APE10-dist-in 6.6787 APE9-dist-in 4.0846 None None CME161 XRAY 1.6 0.183 0.227 A 368.0 340.0 0 31 31 0 [[25, 313]] 1.0 6q7t Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6QAGA P28482 11 357 360.0 HUH:404,HUH:405 Type1,Allosteric Inactive DFGin 6.6737 16.3283 BLAminus -131.07, 179.69 59.56, 79.71 -94.59, 23.02 291.33, 80.77 -60.94, -31.24 out-out out 10.1879 Saltbr-out 6.317 HRD-in -68.77, -49.91 69.72, -0.83 out-in-out SNCoio in-out ActLoopNT-in 2.6962 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -85.9, -34.97 APE9-dihe-na -66.74, 159.57 APE8-dihe-in -60.99, 132.48 APE8-rot-in 309.19 APE67-dihe-in -70.55, -17.76 -62.43, -41.0 APE12-dist-out 14.314 APE11-dist-in 10.9391 APE10-dist-in 7.144 APE9-dist-in 4.5323 None None CME161 XRAY 2.07 0.187 0.235 A 368.0 340.0 0 31 31 0 [[25, 313]] 1.0 6qag Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AOAA P28482 11 356 360.0 N83:406,OZU:407 Type1,Allosteric Inactive DFGin 6.7931 16.527 BLAminus -135.38, -176.79 59.99, 79.64 -96.04, 23.18 287.21, 76.82 -63.39, -28.33 out-in out 10.2665 Saltbr-in 2.8684 HRD-in -70.35, -52.0 72.83, 3.26 in-in-out SNCiio in-out ActLoopNT-in 2.7969 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.11, -37.31 APE9-dihe-na -66.5, 160.64 APE8-dihe-in -61.93, 128.37 APE8-rot-in 309.77 APE67-dihe-in -60.49, -16.92 -57.79, -48.55 APE12-dist-out 14.4472 APE11-dist-in 11.0079 APE10-dist-in 6.9063 APE9-dist-in 4.2056 None None CME161 XRAY 1.62 0.182 0.232 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 8aoa Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AODA P28482 11 356 360.0 NY0:404,NYI:405 Type1,Allosteric Inactive DFGin 6.8231 16.0357 BLAminus -131.17, -179.47 57.68, 82.31 -96.08, 20.12 286.18, 76.41 -64.6, -20.71 in-in in 9.9784 Saltbr-in 3.1285 HRD-in -70.94, -51.02 75.95, 2.66 in-in-out SNCiio in-out ActLoopNT-in 2.8057 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.18, -34.01 APE9-dihe-na -67.78, 158.19 APE8-dihe-in -55.04, 129.71 APE8-rot-in 310.11 APE67-dihe-in -63.45, -16.67 -58.94, -47.88 APE12-dist-out 14.4183 APE11-dist-in 11.0901 APE10-dist-in 6.9955 APE9-dist-in 4.2756 None None CME161 XRAY 1.62 0.191 0.227 A 368.0 335.0 4 31 31 0 [[25, 313]] 1.0 8aod Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AOHA P28482 11 356 360.0 N96:405,N96:406 Type1,Allosteric Inactive DFGin 6.8299 16.5947 BLAminus -132.83, 177.1 62.85, 85.04 -99.02, 23.99 285.97, 81.42 -64.74, -29.87 out-in out 10.2677 Saltbr-in 3.4631 HRD-in -72.11, -50.02 74.87, 0.95 in-in-out SNCiio in-out ActLoopNT-in 2.8165 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -90.28, -37.21 APE9-dihe-na -70.91, 159.97 APE8-dihe-in -57.17, 128.99 APE8-rot-in 305.99 APE67-dihe-in -64.24, -15.82 -57.85, -48.55 APE12-dist-out 14.2058 APE11-dist-in 10.9951 APE10-dist-in 6.7768 APE9-dist-in 4.3046 None None CME161 XRAY 1.6 0.172 0.214 A 368.0 334.0 4 31 31 0 [[25, 313]] 1.0 8aoh Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 8AOIA P28482 11 356 360.0 NX0:405,NX0:406 Type1,Allosteric Inactive DFGin 6.8878 16.3934 BLAminus -136.78, 177.1 63.08, 84.65 -99.16, 21.81 286.0, 77.79 -61.3, -28.58 out-in out 10.3656 Saltbr-in 2.8069 HRD-in -73.8, -50.98 78.41, -1.24 in-in-out SNCiio in-out ActLoopNT-in 2.8176 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -92.32, -37.26 APE9-dihe-na -67.19, 156.47 APE8-dihe-in -52.14, 125.91 APE8-rot-in 308.25 APE67-dihe-in -65.16, -15.87 -56.81, -46.51 APE12-dist-out 14.295 APE11-dist-in 10.9812 APE10-dist-in 6.8569 APE9-dist-in 4.3055 None None CME161 XRAY 1.602 0.164 0.202 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 8aoi Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7XC1A P28482 10 360 360.0 5ID:401,B8Z:405 Type1,Allosteric Inactive DFGin 6.7078 15.976 BLAminus -137.71, -179.56 58.01, 78.42 -93.4, 30.18 285.99, 69.28 -65.81, -34.24 in-in in 9.5275 Saltbr-in 2.9997 HRD-in -74.95, -51.9 73.0, -2.02 in-in-out SNCiio in-out ActLoopNT-in 2.7443 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -122.62, 101.42 APE9-dihe-na 74.74, 135.42 APE8-dihe-in -55.35, 136.96 APE8-rot-in 306.98 APE67-dihe-in -57.04, -22.83 -48.83, -53.13 APE12-dist-in 8.7119 APE11-dist-out 7.512 APE10-dist-in 7.787 APE9-dist-in 3.0162 None None NEP125 XRAY 2.09 0.232 0.271 A 368.0 351.0 0 31 31 0 [[25, 313]] 1.0 7xc1 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7X4UA P28482 10 359 360.0 5ID:401,8DK:402,BTB:404 Type1,Allosteric,Allosteric Inactive DFGin 6.9264 15.7569 BLAminus -130.94, 179.99 65.43, 75.46 -94.7, 29.02 282.13, 69.46 -67.73, -25.68 in-out in 9.857 Saltbr-out 4.0629 HRD-in -76.85, -49.01 74.24, 2.54 out-in-in SNCoii in-in ActLoopNT-in 2.6947 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -104.34, -27.33 APE9-dihe-na -70.01, 158.49 APE8-dihe-in -59.37, 130.23 APE8-rot-in 310.67 APE67-dihe-in -64.33, -17.62 -55.67, -49.5 APE12-dist-in 13.752 APE11-dist-in 10.9435 APE10-dist-in 7.171 APE9-dist-in 4.5619 None None None XRAY 1.98 0.199 0.235 A 368.0 350.0 0 31 31 0 [[25, 313]] 1.0 7x4u Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4QTAA P28482 10 358 360.0 38Z:411 Type1.5_Front Inactive DFGin 6.9014 16.419 BLAminus -127.54, 173.07 71.53, 87.6 -104.51, 22.85 289.22, 73.36 -66.57, -25.44 in-in in 9.6271 Saltbr-in 2.6475 HRD-in -72.05, -50.52 77.72, -5.81 in-in-out SNCiio in-out ActLoopNT-in 2.7868 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 141.19 APE8-rot-out 186.7 APE67-dihe-in -78.23, -10.32 -106.34, 7.24 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.45 0.16 0.191 A 361.0 335.0 14 31 17 14 [[25, 313]] 1.0 4qta Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G9DA P28482 8 357 360.0 ER8:406 Type1.5_Front Inactive DFGin 6.8322 16.4174 BLAminus -130.82, 177.58 62.78, 85.24 -103.76, 20.35 283.71, 79.73 -63.11, -28.56 in-in in 9.9441 Saltbr-in 2.6335 HRD-in -73.65, -52.91 75.39, 8.67 in-in-out SNCiio in-out ActLoopNT-in 2.8528 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.6, -41.14 APE9-dihe-na -67.27, 166.02 APE8-dihe-in -67.59, 131.6 APE8-rot-in 309.39 APE67-dihe-in -67.26, -16.88 -58.97, -46.53 APE12-dist-out 14.4705 APE11-dist-in 11.1692 APE10-dist-in 7.0045 APE9-dist-in 4.1624 None None CME161 XRAY 1.8 0.169 0.223 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 6g9d Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G9HA P28482 11 357 360.0 ERW:405 Type1.5_Front Inactive DFGin 6.8629 16.1934 BLAminus -129.54, 176.24 67.51, 84.59 -100.67, 23.24 285.23, 76.32 -64.98, -24.84 out-in out 10.1259 Saltbr-in 2.6489 HRD-in -73.48, -50.99 74.79, 0.78 in-in-out SNCiio in-out ActLoopNT-in 2.8679 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.85, -36.75 APE9-dihe-na -71.44, 161.71 APE8-dihe-in -53.41, 125.25 APE8-rot-in 311.99 APE67-dihe-in -63.79, -17.26 -57.75, -47.59 APE12-dist-out 14.5021 APE11-dist-in 11.1983 APE10-dist-in 7.0379 APE9-dist-in 4.3282 None None CME161 XRAY 1.73 0.164 0.213 A 368.0 344.0 0 31 31 0 [[25, 313]] 1.0 6g9h Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G9JA P28482 8 357 360.0 ERK:403 Type1.5_Front Inactive DFGin 6.8519 16.4502 BLAminus -129.62, 174.38 66.65, 81.52 -99.73, 19.69 286.36, 76.45 -66.94, -21.09 in-in in 9.657 Saltbr-in 2.7199 HRD-in -69.57, -51.16 71.71, 3.51 in-in-out SNCiio in-out ActLoopNT-in 2.7648 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -94.41, -41.74 APE9-dihe-na -65.68, 165.5 APE8-dihe-in -68.67, 127.92 APE8-rot-in 310.31 APE67-dihe-in -68.75, -18.58 -53.05, -47.45 APE12-dist-out 14.7089 APE11-dist-in 11.2293 APE10-dist-in 7.1623 APE9-dist-in 4.3572 None None CME127,CME161,CME166 XRAY 1.98 0.162 0.212 A 368.0 350.0 0 31 31 0 [[25, 313]] 1.0 6g9j Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G9KA P28482 11 357 360.0 ESK:404 Type1.5_Front Inactive DFGin 6.8688 16.5006 BLAminus -127.44, 173.71 64.58, 89.87 -103.62, 17.25 282.92, 76.11 -73.44, -14.72 in-in in 9.7377 Saltbr-in 2.645 HRD-in -66.45, -52.24 73.55, 2.38 in-in-out SNCiio in-out ActLoopNT-in 2.8371 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.11, -41.06 APE9-dihe-na -64.16, 170.62 APE8-dihe-in -77.68, 128.75 APE8-rot-in 308.66 APE67-dihe-in -63.28, -19.27 -55.77, -50.47 APE12-dist-out 14.9684 APE11-dist-in 11.4607 APE10-dist-in 7.3076 APE9-dist-in 4.294 None None CME127,CME161 XRAY 1.94 0.164 0.223 A 368.0 345.0 0 31 31 0 [[25, 313]] 1.0 6g9k Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6G9NA P28482 11 357 360.0 ESN:407 Type1.5_Front Inactive DFGin 7.1331 16.5261 BLAminus -124.73, 175.13 63.57, 85.94 -99.62, 16.39 282.24, 77.66 -74.35, -19.57 out-in out 10.1647 Saltbr-in 2.7503 HRD-in -70.0, -50.46 74.7, 7.06 in-in-out SNCiio in-out ActLoopNT-in 2.8284 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -65.54, 147.38 APE9-dihe-na 67.51, -176.26 APE8-dihe-in -97.0, 144.29 APE8-rot-in 289.97 APE67-dihe-in -64.18, -20.4 -49.42, -51.94 APE12-dist-in 13.6331 APE11-dist-in 11.7222 APE10-dist-out 9.0098 APE9-dist-in 3.2103 None None CME161 XRAY 1.76 0.168 0.218 A 368.0 345.0 0 31 31 0 [[25, 313]] 1.0 6g9n Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6GDMA P28482 8 356 360.0 F3Z:404 Type1.5_Front Inactive DFGin 6.8409 16.5265 BLAminus -126.95, 171.54 65.54, 87.24 -101.62, 18.17 285.3, 73.79 -62.71, -23.55 in-in in 9.6417 Saltbr-in 2.6906 HRD-in -73.55, -51.55 74.53, 5.94 in-in-out SNCiio in-out ActLoopNT-in 2.769 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.91, -41.51 APE9-dihe-na -60.95, 166.12 APE8-dihe-in -74.95, 131.2 APE8-rot-in 307.5 APE67-dihe-in -60.9, -19.09 -57.69, -50.8 APE12-dist-out 14.6522 APE11-dist-in 11.2741 APE10-dist-in 7.2129 APE9-dist-in 4.1072 None None CME65,CME161,CME166,CME254 XRAY 1.91 0.185 0.243 A 368.0 345.0 0 31 31 0 [[25, 313]] 1.0 6gdm Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6GE0A P28482 11 357 360.0 EVQ:406 Type1.5_Front Inactive DFGin 6.8071 16.4086 BLAminus -125.01, 178.42 65.88, 86.44 -104.81, 21.96 285.23, 73.29 -68.51, -20.31 in-in in 9.8525 Saltbr-in 2.6163 HRD-in -69.56, -50.3 73.32, 2.78 in-in-out SNCiio in-out ActLoopNT-in 2.7649 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.29, -38.81 APE9-dihe-na -61.85, 160.75 APE8-dihe-in -56.8, 124.98 APE8-rot-in 313.47 APE67-dihe-in -60.01, -18.82 -53.88, -51.43 APE12-dist-out 14.5856 APE11-dist-in 11.2771 APE10-dist-in 7.3858 APE9-dist-in 4.3302 None None CME127,CME161 XRAY 1.82 0.165 0.21 A 368.0 345.0 0 31 31 0 [[25, 313]] 1.0 6ge0 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6GJDA P28482 10 357 360.0 F0E:411 Type1.5_Front Inactive DFGin 6.7097 16.462 BLAminus -129.58, 174.41 70.7, 91.35 -105.73, 20.26 284.72, 79.09 -64.64, -25.49 in-in in 9.6204 Saltbr-in 2.671 HRD-in -72.09, -52.59 71.97, 4.09 in-in-out SNCiio in-out ActLoopNT-in 2.7977 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.38, -38.44 APE9-dihe-na -62.52, 167.01 APE8-dihe-in -77.48, 126.95 APE8-rot-in 303.11 APE67-dihe-in -62.52, -19.79 -59.63, -41.94 APE12-dist-out 14.4021 APE11-dist-in 11.2419 APE10-dist-in 6.9796 APE9-dist-in 4.093 None None CME161 XRAY 1.58 0.169 0.21 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 6gjd Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7AUVA P28482 11 357 360.0 RYW:405 Type1.5_Front Inactive DFGin 7.0231 16.5748 BLAminus -127.45, 177.69 56.53, 84.41 -94.89, 19.78 285.74, 75.17 -78.04, -13.36 out-in out 10.2302 Saltbr-in 2.7195 HRD-in -72.53, -48.67 70.65, 1.51 in-in-out SNCiio in-out ActLoopNT-in 2.8161 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -92.76, -42.85 APE9-dihe-na -53.93, 163.97 APE8-dihe-in -75.48, 124.43 APE8-rot-in 308.53 APE67-dihe-in -70.04, -12.97 -52.3, -46.84 APE12-dist-out 14.9893 APE11-dist-in 11.5904 APE10-dist-in 7.3836 APE9-dist-in 4.2276 None None CME161 XRAY 1.76 0.17 0.229 A 368.0 347.0 0 31 31 0 [[25, 313]] 1.0 7auv Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7NQQA P28482 11 356 360.0 UMN:406 Type1.5_Front Inactive DFGin 6.9179 16.4916 BLAminus -130.12, 174.13 62.32, 86.15 -100.4, 23.58 286.24, 72.55 -69.75, -20.62 in-in in 9.4689 Saltbr-in 2.6775 HRD-in -65.77, -47.18 66.3, 4.45 in-in-out SNCiio in-out ActLoopNT-in 2.8368 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.75, -32.6 APE9-dihe-na -69.61, 163.37 APE8-dihe-in -60.6, 124.16 APE8-rot-in 315.24 APE67-dihe-in -60.72, -19.47 -52.29, -51.54 APE12-dist-out 14.8002 APE11-dist-in 11.3736 APE10-dist-in 7.4019 APE9-dist-in 4.3443 None None CME161 XRAY 1.943 0.177 0.228 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 7nqq Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7NQWA P28482 11 356 360.0 UNW:405 Type1.5_Front Inactive DFGin 6.8164 16.4185 BLAminus -126.85, 178.18 67.17, 79.44 -98.87, 21.06 284.86, 74.28 -63.45, -23.61 in-in in 9.7825 Saltbr-in 2.5108 HRD-in -71.96, -49.6 74.37, 1.07 in-in-out SNCiio in-out ActLoopNT-in 2.8378 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.4, -37.94 APE9-dihe-na -67.38, 158.88 APE8-dihe-in -52.66, 123.57 APE8-rot-in 311.73 APE67-dihe-in -63.22, -17.02 -54.57, -47.98 APE12-dist-out 14.6259 APE11-dist-in 11.2631 APE10-dist-in 7.1864 APE9-dist-in 4.3805 None None CME161 XRAY 1.775 0.167 0.206 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 7nqw Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7NR5A P28482 11 357 360.0 UOH:405 Type1.5_Front Inactive DFGin 7.1423 16.5156 BLAminus -128.99, 175.71 60.33, 87.75 -101.3, 22.07 283.66, 79.18 -76.03, -20.46 out-in out 10.1304 Saltbr-in 2.6875 HRD-in -71.53, -48.61 67.4, 6.67 in-in-out SNCiio in-out ActLoopNT-in 2.8315 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -66.22, 143.49 APE9-dihe-na 70.29, 179.11 APE8-dihe-in -86.54, 137.23 APE8-rot-in 294.6 APE67-dihe-in -64.14, -18.44 -44.13, -48.47 APE12-dist-in 13.3947 APE11-dist-in 11.5169 APE10-dist-out 9.1457 APE9-dist-in 3.1166 None None CME161 XRAY 1.766 0.176 0.223 A 368.0 342.0 0 31 31 0 [[25, 313]] 1.0 7nr5 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7NR8A P28482 11 356 360.0 UOE:408 Type1.5_Front Inactive DFGin 6.7887 16.6215 BLAminus -131.19, 173.71 59.31, 84.45 -94.57, 22.79 284.69, 71.84 -65.62, -20.38 in-in in 9.9925 Saltbr-in 2.554 HRD-in -71.25, -47.16 78.03, -4.67 in-in-out SNCiio in-out ActLoopNT-in 2.8379 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.57, -40.56 APE9-dihe-na -62.09, 161.08 APE8-dihe-in -53.56, 123.22 APE8-rot-in 309.14 APE67-dihe-in -64.63, -17.01 -54.92, -46.72 APE12-dist-out 14.7709 APE11-dist-in 11.4316 APE10-dist-in 7.4448 APE9-dist-in 4.4485 None None CME161 XRAY 1.627 0.173 0.213 A 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 7nr8 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 7NR9A P28482 11 355 360.0 UOW:402 Type1.5_Front Inactive DFGin 7.1788 16.4455 BLAminus -121.95, 178.87 51.29, 96.32 -108.0, 26.49 285.39, 78.02 -83.88, -16.22 out-in out 10.2063 Saltbr-in 3.2726 HRD-in -66.46, -47.39 67.01, 11.43 in-in-out SNCiio in-out ActLoopNT-in 2.8907 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -152.12, -19.83 APE9-dihe-na -57.71, 157.85 APE8-dihe-in -80.51, 146.4 APE8-rot-in 299.55 APE67-dihe-in -65.28, -14.73 -65.27, -45.43 APE12-dist-out 14.6652 APE11-dist-in 11.277 APE10-dist-in 7.2977 APE9-dist-in 3.5596 None None CME161 XRAY 1.906 0.248 0.308 A 368.0 335.0 0 31 31 0 [[25, 313]] 1.0 7nr9 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6QAQA P28482 11 357 360.0 HVQ:405,HVQ:406 Type3,Allosteric Inactive DFGin 6.7435 16.3369 BLAminus -132.48, -175.44 58.62, 75.9 -89.63, 27.24 287.47, 77.62 -68.43, -20.91 out-out out 10.3958 Saltbr-out 7.243 HRD-in -74.45, -53.84 73.42, -0.11 out-in-in SNCoii in-in ActLoopNT-in 2.7384 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -80.4, -31.75 APE9-dihe-na -86.25, 162.01 APE8-dihe-in -58.15, 125.86 APE8-rot-in 312.66 APE67-dihe-in -63.66, -17.77 -47.47, -55.55 APE12-dist-in 13.8408 APE11-dist-in 10.7951 APE10-dist-in 6.2969 APE9-dist-in 4.414 None None CME161 XRAY 1.58 0.19 0.229 A 368.0 344.0 0 31 31 0 [[25, 313]] 1.0 6qaq Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FV4A P28482 9 357 360.0 EK7:60401 Type1 None DFGin 6.9263 15.4894 BLAminus -127.76, 178.3 63.88, 86.85 -108.47, 28.84 281.36, 73.37 -69.43, -40.09 in-in in 9.6423 Saltbr-in 2.6484 HRD-in -75.2, -46.77 73.02, -3.37 in-in-none SNCiin in-none ActLoopNT-in 2.8368 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -41.0 APE9-dihe-na -73.39, 169.26 APE8-dihe-in -71.16, 102.82 APE8-rot-in 309.16 APE67-dihe-in -58.85, -32.49 -29.11, -51.69 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.3768 APE9-dist-in 4.3706 None None CME161 XRAY 2.5 0.219 0.253 A 360.0 330.0 19 31 19 12 [[25, 313]] 1.0 4fv4 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FV5A P28482 9 357 360.0 EK9:60401 Type1 None DFGin 6.9108 15.4358 BLAminus -125.94, 174.49 65.85, 87.03 -106.87, 28.63 280.66, 75.44 -65.59, -45.85 in-in in 9.3535 Saltbr-in 2.7097 HRD-in -72.18, -50.7 73.7, -7.14 in-in-none SNCiin in-none ActLoopNT-in 2.767 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 177.89 APE8-dihe-in -70.68, 121.16 APE8-rot-in 311.58 APE67-dihe-in -59.32, -29.75 -54.36, -44.45 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.6417 None None CME161 XRAY 2.4 0.206 0.248 A 360.0 331.0 18 31 17 14 [[25, 313]] 1.0 4fv5 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FV6A P28482 9 357 360.0 E57:60401 Type1 None DFGin 6.9518 14.8135 BLAminus -126.85, -179.36 58.14, 87.74 -105.16, 32.96 280.54, 72.76 -66.83, -48.49 in-in in 9.1188 Saltbr-in 2.7279 HRD-in -73.71, -49.52 71.01, 1.58 in-in-none SNCiin in-none ActLoopNT-in 2.7775 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 164.79 APE8-dihe-in -71.11, 129.52 APE8-rot-in 305.06 APE67-dihe-in -62.14, -26.42 -57.08, -45.77 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.348 None None None XRAY 2.5 0.222 0.249 A 360.0 332.0 17 31 17 14 [[25, 313]] 1.0 4fv6 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FV8A P28482 8 357 360.0 E63:60401 Type1 None DFGin 7.006 15.497 BLAminus -127.0, -178.27 61.48, 83.09 -106.04, 21.77 282.14, 67.68 -61.35, -37.24 in-in in 9.5314 Saltbr-in 2.8516 HRD-in -71.05, -46.98 70.21, -0.53 in-in-none SNCiin in-none ActLoopNT-in 2.737 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -57.07 APE9-dihe-na -109.25, -165.95 APE8-dihe-in -76.52, 120.67 APE8-rot-in 315.06 APE67-dihe-in -62.49, -24.63 -55.08, -35.49 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.5361 APE9-dist-in 4.7209 None None CME161 XRAY 2.0 0.188 0.227 A 360.0 334.0 16 31 18 13 [[25, 313]] 1.0 4fv8 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 4FV9A P28482 8 357 360.0 E71:60401 Type1 None DFGin 6.9285 15.6357 BLAminus -132.32, -178.13 60.98, 82.89 -105.46, 23.11 283.0, 73.52 -62.53, -38.05 in-in in 9.598 Saltbr-in 3.0385 HRD-in -72.61, -49.16 72.56, -1.28 in-in-none SNCiin in-none ActLoopNT-in 2.7432 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 179.68 APE8-dihe-in -79.93, 120.69 APE8-rot-in 307.61 APE67-dihe-in -59.23, -20.77 -43.94, -53.86 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.5688 None None CME161 XRAY 2.11 0.201 0.238 A 360.0 332.0 18 31 17 14 [[25, 313]] 1.0 4fv9 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5BUEA P28482 11 358 360.0 4V8:60401 Type1 None DFGin 6.9001 15.2237 BLAminus -122.39, -177.08 63.38, 82.69 -105.24, 21.84 282.5, 70.9 -61.62, -35.58 in-in in 9.2556 Saltbr-in 2.813 HRD-in -71.44, -49.4 73.74, -0.74 in-in-none SNCiin in-none ActLoopNT-in 2.7935 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 136.04 APE8-rot-in 329.09 APE67-dihe-in -60.95, -23.57 -107.06, -4.75 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.4 0.185 0.23 A 361.0 329.0 19 31 16 15 [[25, 313]] 1.0 5bue Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5BUIA P28482 11 358 360.0 4V9:60402 Type1 None DFGin 6.9906 15.3004 BLAminus -130.19, 179.53 65.05, 80.02 -99.3, 20.21 283.96, 66.32 -59.55, -33.7 in-in in 9.5493 Saltbr-in 2.722 HRD-in -68.56, -51.77 75.84, -7.59 in-in-none SNCiin in-none ActLoopNT-in 2.8456 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -130.01 APE8-rot-in 334.62 APE67-dihe-in -56.78, -27.08 -106.13, -3.49 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.12 0.172 0.222 A 361.0 338.0 10 31 21 10 [[25, 313]] 1.0 5bui Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5BUJA P28482 9 358 360.0 4VB:60401 Type1 None DFGin 6.9988 15.405 BLAminus -125.43, -179.58 67.11, 82.68 -104.4, 22.22 283.46, 67.98 -61.34, -32.84 in-in in 9.5259 Saltbr-in 2.6939 HRD-in -77.84, -46.67 74.74, -8.15 in-in-none SNCiin in-none ActLoopNT-in 2.7868 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 127.23 APE8-rot-in 314.32 APE67-dihe-in -58.67, -24.13 -104.72, -0.52 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.85 0.173 0.206 A 361.0 331.0 19 31 16 15 [[25, 313]] 1.0 5buj Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5BVDA P28482 9 358 360.0 4VF:60401 Type1 None DFGin 7.0124 14.8201 BLAminus -120.88, -174.96 58.49, 83.25 -99.87, 23.43 283.53, 71.8 -56.85, -34.73 in-in in 9.2645 Saltbr-in 2.6271 HRD-in -80.64, -49.81 78.16, -6.37 in-in-none SNCiin in-none ActLoopNT-in 2.7197 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 122.19 APE8-rot-in 306.38 APE67-dihe-in -62.44, -24.22 -51.26, -49.02 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.9 0.172 0.207 A 361.0 330.0 20 31 15 16 [[25, 313]] 1.0 5bvd Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5BVEA P28482 9 358 360.0 4VG:60401 Type1 None DFGin 6.9949 14.7747 BLAminus -125.12, -174.29 54.55, 82.42 -96.55, 21.3 282.29, 70.85 -61.67, -24.38 in-in in 9.1394 Saltbr-in 2.729 HRD-in -80.4, -49.72 75.16, -2.3 in-in-none SNCiin in-none ActLoopNT-in 2.781 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 121.36 APE8-rot-in 307.25 APE67-dihe-in -61.28, -26.45 -50.74, -47.6 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.0 0.175 0.22 A 361.0 330.0 20 31 15 16 [[25, 313]] 1.0 5bve Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 5BVFA P28482 9 358 360.0 4VJ:60401 Type1 None DFGin 6.8009 14.7141 BLAminus -123.98, -172.37 55.64, 78.56 -97.05, 25.41 283.39, 68.26 -60.16, -26.7 in-in in 9.2625 Saltbr-in 2.6896 HRD-in -79.7, -47.41 71.71, 1.48 in-in-none SNCiin in-none ActLoopNT-in 2.6907 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -57.62, -24.81 999.0, -48.13 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.9 0.183 0.221 A 361.0 327.0 23 31 14 17 [[25, 313]] 1.0 5bvf Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.2e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 3I5ZA P28482 8 357 360.0 Z48:60401 Type1 None DFGin 6.9174 15.2488 BLAminus -127.32, 174.22 70.2, 66.73 -83.95, 23.54 288.3, 68.12 -65.3, -33.09 in-in in 9.3126 Saltbr-in 2.7151 HRD-in -75.44, -48.03 71.03, -6.74 in-in-none SNCiin in-none ActLoopNT-in 2.7171 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -13.55 APE9-dihe-na -121.16, 175.77 APE8-dihe-in -61.26, 116.09 APE8-rot-in 314.5 APE67-dihe-in -57.72, -29.32 -61.25, -36.48 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.8123 APE9-dist-in 4.9538 None None None XRAY 2.2 0.217 0.258 A 380.0 331.0 19 31 17 14 [[25, 313]] 1.0 3i5z Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 3I60A P28482 8 358 360.0 E86:60401 Type1 None DFGin 6.9679 15.1526 BLAminus -121.98, 176.49 63.3, 79.85 -98.81, 21.48 280.47, 70.03 -59.78, -40.19 in-in in 9.2893 Saltbr-in 3.1109 HRD-in -73.88, -46.85 79.23, -3.42 in-in-none SNCiin in-none ActLoopNT-in 2.7524 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -172.19 APE8-dihe-in -93.47, 121.54 APE8-rot-in 308.65 APE67-dihe-in -68.68, -19.01 -43.75, -44.65 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.4957 None None None XRAY 2.5 0.211 0.248 A 380.0 335.0 16 31 18 13 [[25, 313]] 1.0 3i60 Homo sapiens CMGC_MAPK1_HUMAN CMGC 1.1e-85 293.5 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_HUMAN 6OPIA P28482 10 356 360.0 N0V:60401 Type1.5_Front None DFGin 6.8164 16.4941 BLAminus -135.48, 169.13 71.03, 93.69 -111.04, 34.22 293.24, 78.08 -67.49, -29.15 in-in in 9.8919 Saltbr-in 3.0541 HRD-in -72.72, -50.31 76.41, -2.79 in-in-none SNCiin in-none ActLoopNT-in 2.8075 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 138.69 APE8-rot-in 306.85 APE67-dihe-in -62.81, -15.96 -67.99, -45.38 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None TPO185,PTR187 TPO185,PTR187 XRAY 3.0 0.189 0.26 A 354.0 326.0 17 31 19 12 [[25, 313]] 1.0 6opi Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.6e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3ZUVA P63086 3 358 358.0 No_ligand No_ligand Active DFGin 6.8481 16.0922 BLAminus -133.65, -165.63 47.31, 79.28 -98.88, 11.99 277.19, 74.23 -55.55, -32.12 out-in out 10.0059 Saltbr-in 2.8055 HRD-in -79.74, -48.77 75.23, 9.95 in-in-in SNCiii in-in ActLoopNT-in 2.8269 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -118.75, 171.21 APE9-dihe-na 66.75, 153.3 APE8-dihe-in -75.0, 135.66 APE8-rot-in 294.16 APE67-dihe-in -61.53, -6.75 -41.14, -56.91 APE12-dist-in 13.0103 APE11-dist-in 11.0438 APE10-dist-in 6.9795 APE9-dist-in 2.9275 None TPO183,PTR185 TPO183,PTR185 XRAY 2.72 0.178 0.23 A 364.0 356.0 0 31 31 0 [[23, 311]] 1.0 3zuv Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3ZUVC P63086 3 358 358.0 No_ligand No_ligand Active DFGin 6.8584 15.9524 BLAminus -132.51, -167.35 55.02, 75.95 -92.55, 22.14 285.34, 69.26 -63.7, -35.45 out-in out 10.2463 Saltbr-in 3.004 HRD-in -69.99, -55.08 76.64, 11.33 in-in-in SNCiii in-in ActLoopNT-in 2.952 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.97, 163.62 APE9-dihe-na 66.94, 113.14 APE8-dihe-in -36.38, 138.15 APE8-rot-in 306.69 APE67-dihe-in -65.92, -14.38 -40.78, -57.92 APE12-dist-in 12.8947 APE11-dist-in 10.7853 APE10-dist-in 7.0763 APE9-dist-in 3.0808 None TPO183,PTR185 TPO183,PTR185 XRAY 2.72 0.178 0.23 C 364.0 356.0 0 31 31 0 [[23, 311]] 1.0 3zuv Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 2ERKA P63086 6 358 358.0 No_ligand No_ligand Active DFGin 6.8812 16.1828 BLAminus -131.49, -174.52 51.55, 76.13 -93.95, 24.88 283.85, 70.54 -64.25, -32.22 out-in out 10.2306 Saltbr-in 3.3951 HRD-in -66.75, -47.09 67.93, 5.7 in-in-in SNCiii in-in ActLoopNT-in 2.736 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.33, 162.31 APE9-dihe-na 70.29, 158.85 APE8-dihe-in -78.8, 134.95 APE8-rot-in 293.27 APE67-dihe-in -57.35, -16.08 -38.3, -60.44 APE12-dist-in 12.7429 APE11-dist-in 10.712 APE10-dist-in 6.772 APE9-dist-in 2.9365 None TPO183,PTR185 TPO183,PTR185 XRAY 2.4 0.192 0.264 A 365.0 353.0 0 31 31 0 [[23, 311]] 1.0 2erk Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6OPKA P63086 9 354 358.0 390:401 Type1 Active DFGin 6.6542 14.7552 BLAminus -124.25, -173.22 49.18, 87.88 -102.56, 22.49 282.63, 69.81 -58.83, -33.74 in-in in 9.2501 Saltbr-in 2.6489 HRD-in -78.1, -60.74 80.93, 7.16 in-in-in SNCiii in-in ActLoopNT-in 2.9386 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -91.49, 173.12 APE9-dihe-na 65.2, 169.84 APE8-dihe-in -91.59, 138.21 APE8-rot-in 292.7 APE67-dihe-in -63.57, -14.22 -44.54, -55.14 APE12-dist-in 12.7505 APE11-dist-in 11.1804 APE10-dist-in 6.8439 APE9-dist-in 2.9753 None TPO183,PTR185 TPO183,PTR185 XRAY 2.54 0.196 0.241 A 352.0 346.0 0 31 31 0 [[23, 311]] 1.0 6opk Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4S33A P63086 4 355 358.0 ANP:401 ATPlike Inactive DFGin 6.7431 16.086 BLAminus -130.86, 178.79 71.13, 76.62 -98.92, 24.03 286.96, 71.68 -62.72, -21.16 in-in in 9.6873 Saltbr-in 2.6802 HRD-in -72.9, -49.96 78.15, -0.96 in-in-out SNCiio in-out ActLoopNT-in 2.8648 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -104.41, -43.84 APE9-dihe-na -64.59, 164.35 APE8-dihe-in -56.21, 123.2 APE8-rot-in 315.9 APE67-dihe-in -61.37, -21.31 -48.55, -49.93 APE12-dist-out 14.7318 APE11-dist-in 11.3056 APE10-dist-in 7.3108 APE9-dist-in 4.4832 R65S None None XRAY 1.48 0.199 0.239 A 358.0 347.0 0 31 31 0 [[23, 311]] 1.0 4s33 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.5e-85 293.0 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4S32A P63086 4 354 358.0 ANP:401 ATPlike Inactive DFGin 6.6461 16.3353 BLAminus -133.92, 176.75 65.37, 79.23 -97.7, 23.57 287.97, 74.34 -66.64, -19.31 in-out in 9.8686 Saltbr-out 3.654 HRD-in -75.76, -45.6 71.68, 4.61 out-in-out SNCoio in-out ActLoopNT-in 2.8278 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.88, -32.08 APE9-dihe-na -65.5, 159.94 APE8-dihe-in -53.88, 129.7 APE8-rot-in 310.08 APE67-dihe-in -61.98, -20.6 -58.72, -45.65 APE12-dist-out 14.5455 APE11-dist-in 11.219 APE10-dist-in 7.4905 APE9-dist-in 4.4333 None None None XRAY 1.34 0.199 0.231 A 358.0 346.0 0 31 31 0 [[23, 311]] 1.0 4s32 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4GT3A P63086 9 356 358.0 ATP:402 ATPlike Inactive DFGin 6.7027 16.1444 BLAminus -134.54, -176.44 66.94, 76.71 -104.84, 22.9 282.81, 76.31 -55.64, -34.0 in-none in 9.8171 Saltbr-none 999.0 HRD-in -69.89, -50.79 79.79, -14.59 none-in-out SNCnio in-out ActLoopNT-in 2.7761 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -105.46, -44.03 APE9-dihe-na -70.04, 169.29 APE8-dihe-in -70.71, 123.51 APE8-rot-in 309.48 APE67-dihe-in -61.98, -17.54 -56.41, -47.97 APE12-dist-out 14.2886 APE11-dist-in 11.0026 APE10-dist-in 6.7399 APE9-dist-in 4.4218 None None CME159 XRAY 1.68 0.168 0.2 A 364.0 348.0 0 31 31 0 [[23, 311]] 1.0 4gt3 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4GVAA P63086 11 356 358.0 ADP:401 ATPlike Inactive DFGin 6.7023 16.7688 BLAminus -137.11, 178.59 63.89, 77.38 -94.14, 25.17 286.58, 79.57 -59.17, -35.22 out-out out 10.4922 Saltbr-out 6.5214 HRD-in -67.64, -55.15 72.72, 9.25 out-in-in SNCoii in-in ActLoopNT-in 2.8301 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -101.68, -13.3 APE9-dihe-na -77.88, 161.53 APE8-dihe-in -56.04, 126.28 APE8-rot-in 320.84 APE67-dihe-in -66.77, -13.08 -47.2, -54.23 APE12-dist-in 13.8449 APE11-dist-in 11.0504 APE10-dist-in 7.1482 APE9-dist-in 4.1983 None None CME159 XRAY 1.83 0.191 0.241 A 364.0 346.0 0 31 31 0 [[23, 311]] 1.0 4gva Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 7UGBA P63086 9 354 358.0 ANP:60401 ATPlike Inactive DFGin 6.8438 15.6136 BLAminus -132.85, -175.34 66.19, 68.8 -95.15, 22.62 283.13, 71.04 -65.04, -17.4 in-in in 9.2984 Saltbr-in 3.0947 HRD-in -74.44, -45.95 75.99, -7.39 in-in-out SNCiio in-out ActLoopNT-in 2.7599 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -141.06, 152.87 APE9-dihe-na -67.4, -32.8 APE8-dihe-in -151.29, 138.48 APE8-rot-out 186.29 APE67-dihe-in -67.11, -12.06 -109.33, 7.55 APE12-dist-in 8.5189 APE11-dist-in 12.1904 APE10-dist-out 9.145 APE9-dist-out 11.3673 None None None XRAY 1.9 0.181 0.228 A 380.0 333.0 9 31 22 9 [[23, 311]] 1.0 7ugb Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.6e-85 292.9 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4S34A P63086 4 354 358.0 ANP:402 ATPlike Inactive DFGin 6.9305 15.9209 BLAminus -141.95, 172.44 70.56, 81.84 -99.71, 28.41 294.26, 76.1 -60.19, -38.53 in-out in 9.8624 Saltbr-out 3.6484 HRD-in -79.44, -51.86 83.9, -4.35 out-in-out SNCoio in-out ActLoopNT-in 2.8808 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.12, -42.94 APE9-dihe-na -58.97, 168.13 APE8-dihe-in -69.02, 123.37 APE8-rot-in 313.04 APE67-dihe-in -67.86, -24.53 -49.65, -45.75 APE12-dist-out 14.8428 APE11-dist-in 11.3273 APE10-dist-in 7.2767 APE9-dist-in 4.4811 I84A None None XRAY 2.5 0.182 0.255 A 358.0 343.0 0 31 31 0 [[23, 311]] 1.0 4s34 Rattus norvegicus CMGC_MAPK1_RAT CMGC 2.9e-85 292.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 1GOLA P63086 2 358 358.0 ATP:581 ATPlike Inactive DFGin 6.8401 16.5086 BLAminus -138.32, 175.35 71.89, 79.82 -106.15, 29.68 287.28, 71.38 -70.4, -19.75 out-none out 10.4077 Saltbr-none 999.0 HRD-in -68.54, -52.86 75.92, 1.19 none-in-out SNCnio in-out ActLoopNT-in 2.8991 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.2, -24.36 APE9-dihe-na -62.06, 164.48 APE8-dihe-in -61.17, 119.13 APE8-rot-in 302.33 APE67-dihe-in -53.15, -25.45 -41.46, -58.53 APE12-dist-out 14.3386 APE11-dist-in 11.2075 APE10-dist-in 7.401 APE9-dist-in 4.2815 K52R None None XRAY 2.8 999.0 999.0 A 364.0 357.0 0 31 31 0 [[23, 311]] 1.0 1gol Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-84 289.8 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8RQVA P63086 4 354 358.0 ANP:501 ATPlike Inactive DFGin 6.9036 16.0694 BLAminus -129.6, -175.7 63.15, 70.39 -89.62, 28.98 289.85, 76.4 -67.34, -38.13 in-out in 9.7114 Saltbr-out 4.2746 HRD-in -67.81, -55.04 72.76, 2.89 out-in-out SNCoio in-out ActLoopNT-in 2.7655 ActLoopCT-out nonTYR APEdihe_aaini APEdist_oiii APE10-dihe-na -100.88, -30.73 APE9-dihe-na -77.54, 159.87 APE8-dihe-in -50.38, 124.93 APE8-rot-none 999.0 APE67-dihe-in -63.77, -19.96 -54.06, -49.39 APE12-dist-out 14.154 APE11-dist-in 10.7528 APE10-dist-in 7.0254 APE9-dist-in 4.3496 T188A None None XRAY 2.19 0.22 0.268 A 365.0 346.0 0 31 31 0 [[23, 311]] 1.0 8rqv Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.1e-84 290.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8RQXA P63086 4 353 358.0 ANP:501 ATPlike Inactive DFGin 6.7525 15.7711 BLAminus -131.54, -179.98 70.52, 77.44 -96.49, 23.47 286.75, 76.4 -63.49, -27.29 in-out in 9.2826 Saltbr-out 4.0303 HRD-in -71.44, -55.38 74.63, 0.71 out-in-out SNCoio in-out ActLoopNT-in 2.8623 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oiii APE10-dihe-na -102.41, -41.91 APE9-dihe-na -63.48, 155.78 APE8-dihe-in -53.17, 123.33 APE8-rot-na 196.55 APE67-dihe-in -71.02, -16.45 -50.75, -40.77 APE12-dist-out 14.2124 APE11-dist-in 10.7678 APE10-dist-in 6.9866 APE9-dist-in 4.4522 R65S,T188D None None XRAY 1.7 0.199 0.231 A 365.0 344.0 0 31 31 0 [[23, 311]] 1.0 8rqx Rattus norvegicus CMGC_MAPK1_RAT CMGC 3.4e-84 288.6 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8RQWA P63086 4 354 358.0 ANP:501 ATPlike Inactive DFGin 6.8494 16.0159 BLAminus -129.63, 178.83 67.86, 79.37 -97.6, 20.5 285.29, 78.65 -60.41, -30.78 in-out in 9.7711 Saltbr-out 4.0654 HRD-in -69.59, -52.69 70.29, 6.23 out-in-out SNCoio in-out ActLoopNT-in 2.8367 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oiii APE10-dihe-na -111.03, -43.37 APE9-dihe-na -66.74, 156.04 APE8-dihe-in -59.11, 129.69 APE8-rot-na 165.64 APE67-dihe-in -63.23, -21.3 -54.35, -46.88 APE12-dist-out 14.6367 APE11-dist-in 10.9228 APE10-dist-in 6.9125 APE9-dist-in 4.2589 T188E None None XRAY 1.8 0.198 0.231 A 365.0 344.0 0 31 31 0 [[23, 311]] 1.0 8rqw Rattus norvegicus CMGC_MAPK1_RAT CMGC 3e-84 288.8 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6RFPA P63086 3 353 358.0 No_ligand No_ligand Inactive DFGin 6.7509 16.1665 BLAminus -127.92, 177.69 70.53, 82.36 -102.39, 18.51 287.59, 77.75 -57.77, -32.64 out-out out 10.0794 Saltbr-out 4.7547 HRD-in -77.75, -51.22 73.85, 1.99 out-in-in SNCoii in-in ActLoopNT-in 2.8433 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -101.61, -31.13 APE9-dihe-na -71.66, 165.31 APE8-dihe-in -63.21, 127.2 APE8-rot-in 308.34 APE67-dihe-in -65.57, -18.65 -54.13, -47.49 APE12-dist-in 13.9606 APE11-dist-in 10.9198 APE10-dist-in 7.1257 APE9-dist-in 4.3855 K229T,H230D,Y231H None None XRAY 1.74 0.147 0.197 A 378.0 337.0 4 31 31 0 [[23, 311]] 1.0 6rfp Rattus norvegicus CMGC_MAPK1_RAT CMGC 9.2e-86 293.7 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4S2ZA P63086 4 354 358.0 No_ligand No_ligand Inactive DFGin 6.7839 16.4902 BLAminus -133.04, 177.08 65.56, 78.71 -98.61, 27.52 290.68, 72.8 -66.65, -19.57 out-out out 10.3409 Saltbr-out 4.8007 HRD-in -72.43, -50.18 77.78, -1.73 out-in-out SNCoio in-out ActLoopNT-in 2.872 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.81, -37.9 APE9-dihe-na -64.1, 168.33 APE8-dihe-in -63.86, 128.05 APE8-rot-in 314.07 APE67-dihe-in -68.36, -13.94 -53.81, -48.77 APE12-dist-out 14.5792 APE11-dist-in 11.337 APE10-dist-in 7.5883 APE9-dist-in 4.5558 R65S None None XRAY 1.48 0.197 0.221 A 358.0 346.0 0 31 31 0 [[23, 311]] 1.0 4s2z Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.5e-85 293.0 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3R63A P63086 4 358 358.0 No_ligand No_ligand Inactive DFGin 6.8522 16.5941 BLAminus -131.22, -176.1 59.55, 77.84 -95.49, 24.21 286.96, 74.66 -59.37, -28.63 out-out out 10.3683 Saltbr-out 4.5325 HRD-in -72.03, -51.46 73.36, 2.63 out-in-out SNCoio in-out ActLoopNT-in 2.7654 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.69, -33.24 APE9-dihe-na -61.13, 151.44 APE8-dihe-in -42.74, 120.57 APE8-rot-in 313.17 APE67-dihe-in -67.39, -15.26 -50.0, -47.49 APE12-dist-out 14.4449 APE11-dist-in 11.1527 APE10-dist-in 7.3862 APE9-dist-in 4.3397 S246E None None XRAY 1.7 0.25 0.245 A 358.0 347.0 0 31 31 0 [[23, 311]] 1.0 3r63 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6OT6A P63086 9 356 358.0 No_ligand No_ligand Inactive DFGin 6.8401 16.5762 BLAminus -134.12, 179.02 66.48, 79.62 -101.27, 25.26 285.01, 75.77 -68.57, -21.35 out-out out 10.4268 Saltbr-out 6.2293 HRD-in -73.06, -51.9 73.75, 5.33 out-in-out SNCoio in-out ActLoopNT-in 2.729 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -101.44, -35.59 APE9-dihe-na -68.78, 163.48 APE8-dihe-in -61.41, 130.61 APE8-rot-in 309.72 APE67-dihe-in -66.07, -15.96 -59.12, -46.86 APE12-dist-out 14.5315 APE11-dist-in 11.13 APE10-dist-in 7.0961 APE9-dist-in 4.3014 D319N None None XRAY 1.65 0.17 0.201 A 358.0 346.0 0 31 31 0 [[23, 311]] 1.0 6ot6 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6OTSA P63086 7 356 358.0 No_ligand No_ligand Inactive DFGin 6.8308 16.1309 BLAminus -142.48, -172.73 60.21, 66.17 -97.08, 29.42 286.38, 75.36 -63.96, -41.03 out-in out 10.0789 Saltbr-in 3.5058 HRD-in -68.89, -50.67 70.41, 16.9 in-in-out SNCiio in-out ActLoopNT-in 2.7056 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_iioo APE10-dihe-na -143.1, 143.87 APE9-dihe-na -72.43, 115.64 APE8-dihe-out 56.21, 66.19 APE8-rot-out 79.9 APE67-dihe-out -71.29, -45.65 -77.68, 52.22 APE12-dist-in 7.2799 APE11-dist-in 11.6817 APE10-dist-out 8.8259 APE9-dist-out 11.0575 E320K None None XRAY 2.1 0.233 0.264 A 358.0 324.0 18 31 21 10 [[23, 311]] 1.0 6ots Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3O71A P63086 9 354 358.0 No_ligand No_ligand Inactive DFGin 6.8667 16.319 BLAminus -130.16, -179.56 58.84, 79.71 -96.83, 24.07 291.46, 76.59 -55.21, -31.57 in-out in 9.7287 Saltbr-out 4.0364 HRD-in -72.55, -51.65 77.3, -10.89 out-in-out SNCoio in-out ActLoopNT-in 2.7607 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -87.87, 106.02 APE9-dihe-na -161.8, 155.6 APE8-dihe-in -53.25, 130.85 APE8-rot-in 321.28 APE67-dihe-in -65.84, -21.99 -102.05, -4.52 APE12-dist-in 11.0319 APE11-dist-out 7.246 APE10-dist-out 11.6636 APE9-dist-out 8.3598 None None None XRAY 1.95 0.201 0.24 A 358.0 340.0 6 31 26 5 [[23, 311]] 1.0 3o71 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4S31A P63086 4 355 358.0 No_ligand No_ligand Inactive DFGin 6.7729 16.4456 BLAminus -134.85, 175.69 67.38, 78.88 -97.91, 23.78 289.36, 71.89 -62.99, -24.05 out-out out 10.3711 Saltbr-out 4.3622 HRD-in -74.32, -51.14 74.9, 4.48 out-in-out SNCoio in-out ActLoopNT-in 2.8196 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.1, -38.05 APE9-dihe-na -61.18, 155.71 APE8-dihe-in -48.46, 125.56 APE8-rot-in 312.04 APE67-dihe-in -65.39, -17.68 -54.91, -48.02 APE12-dist-out 14.5533 APE11-dist-in 11.0746 APE10-dist-in 7.2421 APE9-dist-in 4.4141 None None None XRAY 1.45 0.211 0.24 A 358.0 347.0 0 31 31 0 [[23, 311]] 1.0 4s31 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 2FYSA P63086 8 356 358.0 No_ligand No_ligand Inactive DFGin 6.6376 16.4772 BLAminus -122.06, 169.63 25.05, 117.45 -113.18, 29.88 284.71, 61.81 -68.75, -32.78 in-out in 9.2572 Saltbr-out 4.193 HRD-in -87.12, -28.64 57.99, -13.75 out-in-out SNCoio in-out ActLoopNT-in 2.6633 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -134.87, 136.79 APE9-dihe-na -45.76, -39.06 APE8-dihe-in -148.7, 156.44 APE8-rot-out 49.9 APE67-dihe-in -64.46, -8.42 -128.65, 6.84 APE12-dist-in 9.1664 APE11-dist-in 12.3683 APE10-dist-out 9.0179 APE9-dist-out 11.2353 None None None XRAY 2.5 0.174 0.266 A 364.0 348.0 1 31 31 0 [[23, 311]] 1.0 2fys Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 2FYSB P63086 8 357 358.0 No_ligand No_ligand Inactive DFGin 6.7764 16.5493 BLAminus -141.27, -177.57 59.65, 89.49 -109.14, 28.54 291.65, 71.85 -72.29, -17.15 in-out in 9.7742 Saltbr-out 4.122 HRD-in -84.25, -43.16 67.41, 9.34 out-in-out SNCoio in-out ActLoopNT-in 2.7291 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -127.69, 133.42 APE9-dihe-na -104.82, 121.89 APE8-dihe-out 70.19, 135.55 APE8-rot-in 303.39 APE67-dihe-in -51.64, -21.24 -129.5, -2.74 APE12-dist-in 10.3843 APE11-dist-in 11.5524 APE10-dist-out 10.8576 APE9-dist-out 10.1251 None None None XRAY 2.5 0.174 0.266 B 364.0 338.0 8 31 23 8 [[23, 311]] 1.0 2fys Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4GSBA P63086 9 356 358.0 No_ligand No_ligand Inactive DFGin 6.7982 16.4904 BLAminus -130.79, 179.48 65.24, 78.76 -98.76, 20.67 284.56, 81.69 -61.23, -26.31 out-out out 10.0051 Saltbr-out 4.3408 HRD-in -72.92, -50.84 79.12, -10.47 out-in-out SNCoio in-out ActLoopNT-in 2.8065 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.36, -33.55 APE9-dihe-na -66.1, 151.89 APE8-dihe-in -42.86, 125.19 APE8-rot-in 317.67 APE67-dihe-in -64.3, -11.6 -62.99, -45.18 APE12-dist-out 14.531 APE11-dist-in 11.1906 APE10-dist-in 7.1304 APE9-dist-in 4.4396 None None CSO63,CME159 XRAY 1.8 0.156 0.199 A 364.0 345.0 3 31 31 0 [[23, 311]] 1.0 4gsb Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 5UMOA P63086 4 354 358.0 No_ligand No_ligand Inactive DFGin 6.9348 16.8433 BLAminus -127.41, 175.69 68.44, 77.39 -96.39, 28.52 286.86, 76.16 -71.36, -25.98 out-out out 10.5225 Saltbr-out 4.4515 HRD-in -72.01, -53.37 77.59, -11.41 out-in-out SNCoio in-out ActLoopNT-in 2.8653 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -93.31, -19.33 APE9-dihe-na -84.58, 165.69 APE8-dihe-in -65.22, 124.13 APE8-rot-in 312.49 APE67-dihe-in -65.69, -19.61 -54.99, -44.8 APE12-dist-out 14.5665 APE11-dist-in 11.2645 APE10-dist-in 7.5201 APE9-dist-in 4.8408 None None None XRAY 2.26 0.15 0.202 A 364.0 347.0 0 31 31 0 [[23, 311]] 1.0 5umo Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3ZU7A P63086 10 353 358.0 No_ligand No_ligand Inactive DFGin 6.7401 16.3406 BLAminus -124.79, 170.31 90.39, 80.99 -109.74, 30.8 288.45, 79.95 -70.99, -23.15 in-out in 9.7404 Saltbr-out 4.4631 HRD-in -72.24, -47.27 72.88, -7.81 out-in-out SNCoio in-out ActLoopNT-in 2.7051 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioo APE10-dihe-na -83.58, -18.35 APE9-dihe-na -93.42, 177.58 APE8-dihe-in -63.85, 148.62 APE8-rot-in 338.25 APE67-dihe-in -61.31, -19.32 -107.88, 5.19 APE12-dist-out 6.9469 APE11-dist-in 12.2123 APE10-dist-out 13.6862 APE9-dist-out 10.5597 None None None XRAY 1.97 0.221 0.269 A 365.0 344.0 0 31 31 0 [[23, 311]] 1.0 3zu7 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 2GPHA P63086 10 354 358.0 No_ligand No_ligand Inactive DFGin 6.7649 16.3749 BLAminus -136.9, -177.95 60.8, 80.27 -101.59, 22.61 284.86, 69.35 -60.66, -26.74 in-in in 9.6244 Saltbr-in 2.931 HRD-in -73.52, -46.58 69.84, -5.14 in-in-out SNCiio in-out ActLoopNT-in 2.9592 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -139.69, 148.7 APE9-dihe-na -65.85, -26.9 APE8-dihe-in -158.6, 145.11 APE8-rot-out 179.4 APE67-dihe-in -65.42, -14.51 -110.57, 9.67 APE12-dist-in 7.7359 APE11-dist-in 10.9274 APE10-dist-out 9.0371 APE9-dist-out 10.9379 T116C None None XRAY 1.9 0.231 0.263 A 364.0 345.0 0 31 31 0 [[23, 311]] 1.0 2gph Rattus norvegicus CMGC_MAPK1_RAT CMGC 2.4e-85 292.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4S30A P63086 4 355 358.0 No_ligand No_ligand Inactive DFGin 6.7914 16.1154 BLAminus -136.9, 174.46 69.38, 77.97 -92.54, 23.46 292.96, 87.93 -67.99, -29.24 out-out out 10.1214 Saltbr-out 5.7799 HRD-in -72.52, -51.08 71.1, -0.94 out-in-out SNCoio in-out ActLoopNT-in 2.7796 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.21, -33.1 APE9-dihe-na -68.08, 160.69 APE8-dihe-in -63.7, 128.99 APE8-rot-in 309.76 APE67-dihe-in -63.41, -20.91 -60.2, -45.12 APE12-dist-out 14.4479 APE11-dist-in 10.9999 APE10-dist-in 7.0966 APE9-dist-in 4.3861 I84A None None XRAY 2.0 0.197 0.249 A 358.0 342.0 1 31 31 0 [[23, 311]] 1.0 4s30 Rattus norvegicus CMGC_MAPK1_RAT CMGC 2.9e-85 292.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8RLXA P63086 4 355 358.0 No_ligand No_ligand Inactive DFGin 6.7939 16.264 BLAminus -136.33, 178.99 67.04, 77.21 -94.32, 26.09 290.49, 80.16 -56.85, -38.35 out-out out 10.1764 Saltbr-out 4.5312 HRD-in -75.47, -50.63 73.32, 2.39 out-in-none SNCoin in-none ActLoopNT-in 2.8342 ActLoopCT-none nonTYR APEdihe_aaini APEdist_iiii APE10-dihe-na -106.61, -38.11 APE9-dihe-na -63.83, 154.99 APE8-dihe-in -45.58, 118.98 APE8-rot-none 999.0 APE67-dihe-in -62.99, -15.78 -47.65, -52.52 APE12-dist-in 13.8742 APE11-dist-in 10.8475 APE10-dist-in 6.9337 APE9-dist-in 4.3195 T188A None None XRAY 1.6 0.212 0.241 A 365.0 347.0 0 31 31 0 [[23, 311]] 1.0 8rlx Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.1e-84 290.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8RMBA P63086 4 355 358.0 No_ligand No_ligand Inactive DFGin 6.6888 16.2958 BLAminus -131.88, -179.07 69.4, 78.54 -94.39, 26.44 287.26, 84.7 -64.41, -26.79 out-out out 10.0298 Saltbr-out 5.0583 HRD-in -69.65, -54.99 73.26, 0.79 out-in-in SNCoii in-in ActLoopNT-in 2.8075 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -96.84, -34.2 APE9-dihe-na -67.31, 156.97 APE8-dihe-in -52.37, 125.49 APE8-rot-na 195.38 APE67-dihe-in -73.42, -16.08 -51.38, -39.59 APE12-dist-in 13.9038 APE11-dist-in 10.7785 APE10-dist-in 7.1438 APE9-dist-in 4.576 R65S,T188D None None XRAY 1.55 0.2 0.23 A 365.0 347.0 0 31 31 0 [[23, 311]] 1.0 8rmb Rattus norvegicus CMGC_MAPK1_RAT CMGC 3.4e-84 288.6 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8RM2A P63086 4 355 358.0 No_ligand No_ligand Inactive DFGin 6.7044 16.2639 BLAminus -136.37, -179.19 65.67, 78.13 -97.92, 25.29 288.31, 76.42 -65.47, -27.78 in-out in 9.9641 Saltbr-out 4.5016 HRD-in -74.12, -52.33 76.93, -0.81 out-in-in SNCoii in-in ActLoopNT-in 2.7539 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -97.51, -40.55 APE9-dihe-na -66.04, 156.07 APE8-dihe-in -54.82, 132.13 APE8-rot-na 160.84 APE67-dihe-in -66.17, -16.18 -56.01, -48.51 APE12-dist-in 13.9982 APE11-dist-in 10.8253 APE10-dist-in 6.8694 APE9-dist-in 4.3776 T188E None None XRAY 1.55 0.202 0.236 A 365.0 347.0 0 31 31 0 [[23, 311]] 1.0 8rm2 Rattus norvegicus CMGC_MAPK1_RAT CMGC 3e-84 288.8 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XNEA P63086 9 354 358.0 TT4:401 Type1 Inactive DFGin 6.9062 16.5377 BLAminus -133.08, -178.31 62.87, 82.73 -101.62, 22.85 284.09, 79.92 -64.02, -26.26 out-out out 10.1683 Saltbr-out 6.631 HRD-in -73.52, -52.79 76.63, -2.65 out-in-out SNCoio in-out ActLoopNT-in 2.8538 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.86, -29.72 APE9-dihe-na -76.47, 164.24 APE8-dihe-in -60.32, 126.3 APE8-rot-in 310.6 APE67-dihe-in -64.56, -12.88 -50.2, -52.63 APE12-dist-out 14.3098 APE11-dist-in 11.1262 APE10-dist-in 7.0874 APE9-dist-in 4.4212 None None CME159,CME252 XRAY 1.8 0.18 0.218 A 346.0 346.0 0 31 31 0 [[23, 311]] 1.0 4xne Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.4 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XRJA P63086 9 354 358.0 620:401 Type1 Inactive DFGin 6.9642 17.0399 BLAminus -135.58, -179.99 62.78, 78.35 -99.18, 21.91 284.15, 79.36 -62.44, -24.71 out-out out 10.8346 Saltbr-out 6.8414 HRD-in -74.76, -52.56 80.19, -5.74 out-in-out SNCoio in-out ActLoopNT-in 2.8729 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -101.08, -24.1 APE9-dihe-na -79.03, 165.2 APE8-dihe-in -60.36, 127.57 APE8-rot-in 312.84 APE67-dihe-in -59.27, -14.85 -52.96, -57.21 APE12-dist-out 14.0217 APE11-dist-in 11.0423 APE10-dist-in 7.1108 APE9-dist-in 4.5185 None None CME159,CME252 XRAY 1.69 0.138 0.18 A 346.0 346.0 0 31 31 0 [[23, 311]] 1.0 4xrj Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.4 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XOYA P63086 9 353 358.0 DX4:401 Type1 Inactive DFGin 6.8384 16.4726 BLAminus -133.37, 174.39 67.24, 87.56 -100.05, 25.74 287.52, 74.09 -60.62, -29.03 out-out out 10.1548 Saltbr-out 6.1211 HRD-in -76.12, -52.95 76.38, -1.71 out-in-none SNCoin in-none ActLoopNT-in 2.7547 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 175.0 APE8-dihe-in -56.7, 130.92 APE8-rot-in 317.45 APE67-dihe-in -61.42, -22.5 -58.06, -51.04 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.6184 None None CME125,CME159,CME164,CME252 XRAY 2.1 0.182 0.218 A 351.0 330.0 8 31 28 3 [[23, 311]] 1.0 4xoy Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XP0A P63086 8 354 358.0 42A:404 Type1 Inactive DFGin 6.729 16.2799 BLAminus -130.85, 176.51 63.35, 87.23 -102.6, 23.78 288.28, 72.28 -57.91, -29.87 in-in in 9.8815 Saltbr-in 3.1124 HRD-in -74.37, -48.16 71.1, 5.03 in-in-out SNCiio in-out ActLoopNT-in 2.8019 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.65, -35.97 APE9-dihe-na -59.06, 154.53 APE8-dihe-in -49.14, 125.19 APE8-rot-in 314.16 APE67-dihe-in -59.44, -18.13 -55.5, -50.72 APE12-dist-out 14.5012 APE11-dist-in 11.2264 APE10-dist-in 7.3188 APE9-dist-in 4.2465 None None CME125,CME159,CME164,CME252 XRAY 1.46 0.192 0.214 A 351.0 340.0 0 31 31 0 [[23, 311]] 1.0 4xp0 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XP2A P63086 8 353 358.0 TT4:401 Type1 Inactive DFGin 6.6105 16.3478 BLAminus -133.41, 176.73 60.84, 85.42 -101.78, 22.05 288.36, 75.74 -60.65, -27.7 in-in in 9.7181 Saltbr-in 2.5334 HRD-in -72.91, -49.95 73.33, 0.56 in-in-out SNCiio in-out ActLoopNT-in 2.758 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -113.44, -29.8 APE9-dihe-na -58.45, 157.07 APE8-dihe-in -60.02, 123.7 APE8-rot-in 308.55 APE67-dihe-in -60.45, -18.84 -52.73, -49.68 APE12-dist-out 14.4688 APE11-dist-in 11.2247 APE10-dist-in 7.4964 APE9-dist-in 4.1831 None None CME159,CME252 XRAY 1.748 0.187 0.226 A 351.0 339.0 0 31 31 0 [[23, 311]] 1.0 4xp2 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XP3A P63086 8 354 358.0 DX4:401 Type1 Inactive DFGin 6.6537 16.0826 BLAminus -130.71, 174.0 60.88, 94.31 -106.94, 16.18 286.8, 78.81 -56.37, -28.23 in-out in 9.2564 Saltbr-out 5.2988 HRD-in -68.04, -51.13 71.44, 6.73 out-in-out SNCoio in-out ActLoopNT-in 2.821 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -121.82, 140.79 APE9-dihe-na 65.58, 179.47 APE8-dihe-in -91.24, 138.76 APE8-rot-in 296.06 APE67-dihe-in -60.07, -19.89 -42.76, -56.06 APE12-dist-in 13.6573 APE11-dist-in 11.2991 APE10-dist-out 9.0284 APE9-dist-in 3.1168 None None CME159,CME252 XRAY 1.782 0.15 0.179 A 351.0 341.0 0 31 31 0 [[23, 311]] 1.0 4xp3 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XRLA P63086 9 353 358.0 42A:402 Type1 Inactive DFGin 7.0316 16.4285 BLAminus -137.37, 172.94 64.21, 83.48 -101.2, 28.73 286.34, 64.33 -56.83, -41.4 out-in out 10.395 Saltbr-in 2.905 HRD-in -74.03, -50.49 73.87, 0.12 in-in-out SNCiio in-out ActLoopNT-in 2.8704 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na 75.98, -50.6 APE9-dihe-na -70.82, 161.2 APE8-dihe-in -60.45, 124.5 APE8-rot-in 303.76 APE67-dihe-in -59.6, -25.0 -51.49, -45.85 APE12-dist-out 14.4346 APE11-dist-in 11.7996 APE10-dist-in 7.3873 APE9-dist-in 4.1646 None None CME159 XRAY 2.554 0.162 0.229 A 345.0 338.0 0 31 31 0 [[23, 311]] 1.0 4xrl Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-84 290.0 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3C9WB P63086 6 354 358.0 HMY:1 Type1 Inactive DFGin 6.8713 15.7027 BLAminus -125.5, 170.88 61.8, 86.37 -105.46, 23.49 285.92, 70.36 -59.57, -35.08 in-out in 9.6739 Saltbr-out 5.1892 HRD-in -69.95, -57.99 88.54, -19.52 out-in-out SNCoio in-out ActLoopNT-in 2.739 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 93.1 APE8-rot-out 58.72 APE67-dihe-in -69.2, -21.0 -95.38, -7.01 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.197 0.274 B 357.0 336.0 13 31 18 13 [[23, 311]] 1.0 3c9w Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3ERKA P63086 6 355 358.0 SB4:800 Type1 Inactive DFGin 6.8828 16.5322 BLAminus -139.22, -175.27 62.55, 73.77 -98.77, 35.79 290.73, 71.27 -71.49, -19.85 out-out out 10.927 Saltbr-out 5.3764 HRD-in -66.65, -56.58 79.91, -6.17 out-in-out SNCoio in-out ActLoopNT-in 2.6518 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -104.75, -13.21 APE9-dihe-na -70.1, 154.45 APE8-dihe-in -51.93, 121.15 APE8-rot-in 313.05 APE67-dihe-in -54.85, -23.36 -42.38, -58.29 APE12-dist-out 14.2105 APE11-dist-in 10.8863 APE10-dist-in 7.3527 APE9-dist-in 4.4886 None None None XRAY 2.1 0.206 0.262 A 364.0 350.0 0 31 31 0 [[23, 311]] 1.0 3erk Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3QYWA P63086 9 354 358.0 6PB:359 Type1 Inactive DFGin 6.7724 16.2423 BLAminus -126.27, 171.8 63.41, 90.28 -101.23, 17.9 289.06, 76.0 -65.58, -21.25 in-out in 9.3847 Saltbr-out 5.4393 HRD-in -66.37, -52.17 74.75, 5.18 out-in-out SNCoio in-out ActLoopNT-in 2.8182 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -136.78, 141.02 APE9-dihe-na 67.83, 177.16 APE8-dihe-in -91.69, 140.04 APE8-rot-in 293.79 APE67-dihe-in -60.96, -17.88 -42.17, -57.45 APE12-dist-in 13.9314 APE11-dist-in 11.6311 APE10-dist-out 9.179 APE9-dist-in 3.2153 None None CME159 XRAY 1.5 0.16 0.188 A 364.0 341.0 0 31 31 0 [[23, 311]] 1.0 3qyw Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3QYZA P63086 8 354 358.0 Z8B:359 Type1 Inactive DFGin 6.7857 16.1243 BLAminus -131.85, 178.2 59.89, 83.49 -98.52, 20.59 286.71, 75.58 -65.79, -20.07 in-in in 9.3717 Saltbr-in 2.7067 HRD-in -71.88, -48.46 70.69, 5.97 in-in-out SNCiio in-out ActLoopNT-in 2.7745 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -117.88, 145.49 APE9-dihe-na 60.59, 179.24 APE8-dihe-in -89.94, 140.18 APE8-rot-in 293.88 APE67-dihe-in -62.03, -18.79 -42.88, -55.91 APE12-dist-in 13.5933 APE11-dist-in 11.3759 APE10-dist-out 8.9948 APE9-dist-in 3.1779 None None CME159 XRAY 1.46 0.175 0.195 A 364.0 341.0 0 31 31 0 [[23, 311]] 1.0 3qyz Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4ERKA P63086 6 355 358.0 OLO:800 Type1 Inactive DFGin 6.7904 16.323 BLAminus -144.14, 171.66 76.96, 71.97 -100.05, 31.86 291.48, 73.72 -66.9, -29.11 in-out in 9.9825 Saltbr-out 4.3497 HRD-in -62.75, -51.24 74.6, -9.96 out-in-out SNCoio in-out ActLoopNT-in 2.8248 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -92.93, -33.71 APE9-dihe-na -56.55, 147.82 APE8-dihe-in -47.77, 114.88 APE8-rot-in 305.72 APE67-dihe-in -41.49, -37.5 -39.09, -67.78 APE12-dist-out 14.5164 APE11-dist-in 11.0597 APE10-dist-in 7.2622 APE9-dist-in 4.4632 None None None XRAY 2.2 0.214 0.317 A 364.0 350.0 0 31 31 0 [[23, 311]] 1.0 4erk Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FI3A P63086 8 353 358.0 DJ2:405 Type1 Inactive DFGin 6.7482 16.2866 BLAminus -133.02, 179.12 56.62, 85.35 -98.75, 19.07 288.43, 77.21 -64.55, -20.4 in-in in 9.4531 Saltbr-in 2.5724 HRD-in -71.98, -48.68 74.21, 5.14 in-in-out SNCiio in-out ActLoopNT-in 2.7993 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -122.6, 149.83 APE9-dihe-na 60.97, 175.94 APE8-dihe-in -85.79, 141.34 APE8-rot-in 291.41 APE67-dihe-in -61.17, -18.63 -47.71, -53.47 APE12-dist-in 13.5524 APE11-dist-in 11.3859 APE10-dist-out 8.49 APE9-dist-in 3.1813 None None CME159 XRAY 1.52 0.152 0.198 A 364.0 339.0 0 31 31 0 [[23, 311]] 1.0 6fi3 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FI6A P63086 8 354 358.0 DF8:402 Type1 Inactive DFGin 6.7558 16.4271 BLAminus -129.61, 172.76 58.06, 90.55 -101.51, 21.9 287.13, 75.73 -61.55, -23.59 in-in in 9.6594 Saltbr-in 2.4682 HRD-in -74.02, -48.26 72.7, 5.76 in-in-out SNCiio in-out ActLoopNT-in 2.7965 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.07, -39.78 APE9-dihe-na -63.17, 166.3 APE8-dihe-in -68.67, 131.98 APE8-rot-in 309.05 APE67-dihe-in -64.9, -18.21 -59.38, -46.75 APE12-dist-out 14.5364 APE11-dist-in 11.3146 APE10-dist-in 7.2758 APE9-dist-in 4.2458 None None CME159,CME164 XRAY 1.65 0.154 0.196 A 364.0 339.0 0 31 31 0 [[23, 311]] 1.0 6fi6 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FJ0A P63086 9 353 358.0 A3N:406 Type1 Inactive DFGin 6.7195 16.1784 BLAminus -135.64, 179.75 55.58, 87.4 -101.72, 22.32 287.92, 73.95 -61.9, -25.39 in-in in 9.3021 Saltbr-in 2.6443 HRD-in -72.24, -49.4 71.7, 8.31 in-in-out SNCiio in-out ActLoopNT-in 2.7812 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -116.36, 140.79 APE9-dihe-na 65.93, 176.72 APE8-dihe-in -81.1, 141.24 APE8-rot-in 297.94 APE67-dihe-in -62.1, -17.49 -48.27, -52.66 APE12-dist-in 13.4585 APE11-dist-in 11.1445 APE10-dist-out 8.8238 APE9-dist-in 3.1308 None None CME159 XRAY 1.659 0.167 0.194 A 364.0 340.0 0 31 31 0 [[23, 311]] 1.0 6fj0 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FJBA P63086 8 354 358.0 AOC:402 Type1 Inactive DFGin 6.6924 16.4935 BLAminus -133.41, 178.52 59.61, 81.21 -96.96, 30.32 290.24, 65.76 -64.27, -25.03 in-in in 9.5103 Saltbr-in 2.6046 HRD-in -73.42, -48.69 73.94, -2.74 in-in-out SNCiio in-out ActLoopNT-in 2.7664 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.58, -43.1 APE9-dihe-na -61.66, 158.49 APE8-dihe-in -54.91, 131.22 APE8-rot-in 309.46 APE67-dihe-in -61.87, -16.83 -61.29, -49.41 APE12-dist-out 14.5284 APE11-dist-in 11.205 APE10-dist-in 7.3326 APE9-dist-in 4.4251 None None CME159 XRAY 1.85 0.185 0.226 A 364.0 338.0 0 31 31 0 [[23, 311]] 1.0 6fjb Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FLEA P63086 8 353 358.0 DQ2:402 Type1 Inactive DFGin 6.7554 16.3123 BLAminus -132.42, -179.89 61.12, 80.88 -95.96, 21.93 283.86, 75.2 -68.37, -17.45 in-out in 9.8721 Saltbr-out 4.5677 HRD-in -72.01, -49.08 74.41, 3.13 out-in-out SNCoio in-out ActLoopNT-in 2.7779 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.79, -39.57 APE9-dihe-na -62.1, 158.77 APE8-dihe-in -56.99, 128.88 APE8-rot-in 310.95 APE67-dihe-in -63.61, -16.07 -56.12, -51.68 APE12-dist-out 14.5267 APE11-dist-in 11.2518 APE10-dist-in 7.2747 APE9-dist-in 4.2562 None None CME159 XRAY 1.48 0.156 0.194 A 364.0 341.0 0 31 31 0 [[23, 311]] 1.0 6fle Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FLVA P63086 9 354 358.0 DTW:403 Type1 Inactive DFGin 6.8201 16.0817 BLAminus -129.61, 176.45 61.68, 86.4 -102.86, 19.47 290.44, 74.88 -65.53, -18.99 in-in in 9.6931 Saltbr-in 2.8744 HRD-in -65.72, -51.77 75.22, 7.67 in-in-out SNCiio in-out ActLoopNT-in 2.7693 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -127.84, 139.67 APE9-dihe-na 67.16, 178.45 APE8-dihe-in -90.65, 145.23 APE8-rot-in 298.33 APE67-dihe-in -64.07, -18.24 -51.2, -52.88 APE12-dist-in 13.5857 APE11-dist-in 11.5693 APE10-dist-out 8.9673 APE9-dist-in 3.1704 None None CME159 XRAY 1.91 0.193 0.219 A 364.0 345.0 0 31 31 0 [[23, 311]] 1.0 6flv Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FMAA P63086 9 354 358.0 DU8:406 Type1 Inactive DFGin 6.7238 16.151 BLAminus -132.1, 177.54 58.89, 88.96 -101.02, 19.64 286.47, 76.34 -64.51, -22.62 in-in in 9.5167 Saltbr-in 2.8449 HRD-in -73.29, -48.11 70.04, 8.22 in-in-out SNCiio in-out ActLoopNT-in 2.7813 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -114.17, 142.41 APE9-dihe-na 60.94, -176.67 APE8-dihe-in -96.38, 137.03 APE8-rot-in 292.6 APE67-dihe-in -63.9, -17.51 -43.25, -50.72 APE12-dist-in 13.4629 APE11-dist-in 11.0446 APE10-dist-out 8.9074 APE9-dist-in 3.1083 None None CME159 XRAY 1.667 0.145 0.186 A 364.0 341.0 0 31 31 0 [[23, 311]] 1.0 6fma Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FN5A P63086 9 354 358.0 DVZ:401 Type1 Inactive DFGin 6.666 16.1829 BLAminus -133.39, -179.42 58.41, 90.82 -107.26, 25.27 285.06, 71.41 -66.7, -23.69 out-in out 10.1183 Saltbr-in 2.3051 HRD-in -70.03, -53.72 74.31, 2.57 in-in-out SNCiio in-out ActLoopNT-in 2.8771 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -114.46, -41.07 APE9-dihe-na -60.45, 164.43 APE8-dihe-in -64.82, 127.21 APE8-rot-in 303.54 APE67-dihe-in -60.71, -17.61 -58.58, -49.17 APE12-dist-out 14.5752 APE11-dist-in 11.326 APE10-dist-in 7.3582 APE9-dist-in 4.3175 None None CME159 XRAY 1.932 0.209 0.241 A 364.0 336.0 2 31 31 0 [[23, 311]] 1.0 6fn5 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FQ7A P63086 9 354 358.0 E2K:403 Type1 Inactive DFGin 6.7343 16.2785 BLAminus -130.32, 175.59 58.0, 91.1 -100.86, 17.55 289.19, 77.23 -64.87, -20.52 in-out in 9.5602 Saltbr-out 4.2788 HRD-in -69.51, -49.87 69.84, 9.15 out-in-out SNCoio in-out ActLoopNT-in 2.8212 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -125.72, 147.96 APE9-dihe-na 61.2, 155.67 APE8-dihe-in -48.79, 131.74 APE8-rot-in 305.11 APE67-dihe-in -62.45, -19.67 -49.62, -53.07 APE12-dist-in 13.684 APE11-dist-in 11.5437 APE10-dist-out 8.5248 APE9-dist-in 3.3163 None None CME159 XRAY 1.6 0.139 0.18 A 364.0 342.0 0 31 31 0 [[23, 311]] 1.0 6fq7 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FR1A P63086 9 354 358.0 E3K:408 Type1 Inactive DFGin 6.7164 16.5026 BLAminus -132.59, 178.04 61.94, 83.51 -99.58, 19.2 286.68, 75.23 -65.16, -18.28 in-out in 9.6485 Saltbr-out 4.06 HRD-in -71.67, -49.57 72.07, 6.53 out-in-out SNCoio in-out ActLoopNT-in 2.7833 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -118.52, 141.33 APE9-dihe-na 65.72, 174.93 APE8-dihe-in -83.88, 143.1 APE8-rot-in 296.31 APE67-dihe-in -63.95, -18.29 -49.1, -51.62 APE12-dist-in 13.5041 APE11-dist-in 11.3391 APE10-dist-out 8.8365 APE9-dist-in 3.1101 None None CME159 XRAY 1.561 0.154 0.199 A 364.0 342.0 0 31 31 0 [[23, 311]] 1.0 6fr1 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FRPA P63086 9 354 358.0 ZAS:407 Type1 Inactive DFGin 6.6647 16.0618 BLAminus -136.36, -179.11 56.41, 86.75 -99.02, 23.85 287.92, 74.74 -61.43, -28.68 in-out in 9.4539 Saltbr-out 4.1408 HRD-in -73.66, -48.98 71.95, 4.21 out-in-out SNCoio in-out ActLoopNT-in 2.7413 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.19, -44.31 APE9-dihe-na -59.59, 164.61 APE8-dihe-in -68.46, 131.84 APE8-rot-in 309.99 APE67-dihe-in -61.95, -18.9 -59.83, -47.47 APE12-dist-out 14.6096 APE11-dist-in 11.2024 APE10-dist-in 7.0802 APE9-dist-in 4.2147 None None CME159 XRAY 1.53 0.164 0.21 A 364.0 340.0 0 31 31 0 [[23, 311]] 1.0 6frp Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FXVA P63086 9 354 358.0 E9W:405 Type1 Inactive DFGin 6.6082 16.6196 BLAminus -133.38, -178.96 57.91, 79.65 -95.09, 25.27 288.04, 71.12 -68.75, -20.09 in-out in 9.8833 Saltbr-out 5.1943 HRD-in -72.43, -47.45 73.54, 4.99 out-in-out SNCoio in-out ActLoopNT-in 2.8056 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -102.75, -41.46 APE9-dihe-na -59.75, 157.53 APE8-dihe-in -51.19, 131.87 APE8-rot-in 312.28 APE67-dihe-in -63.95, -12.15 -64.35, -47.16 APE12-dist-out 14.5614 APE11-dist-in 11.1828 APE10-dist-in 7.3299 APE9-dist-in 4.3142 None None CME159,CME252 XRAY 1.53 0.154 0.193 A 364.0 337.0 1 31 31 0 [[23, 311]] 1.0 6fxv Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR2A P63086 9 354 358.0 WNT:403 Type1 Inactive DFGin 7.1206 15.8412 BLAminus -112.87, 156.99 74.31, 96.4 -102.5, 22.69 283.17, 79.7 -72.9, -13.1 in-in in 9.8905 Saltbr-in 2.7797 HRD-in -74.13, -48.82 72.48, 6.28 in-in-out SNCiio in-out ActLoopNT-in 2.8141 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.08, -38.56 APE9-dihe-na -64.61, 164.24 APE8-dihe-in -61.33, 129.63 APE8-rot-in 313.39 APE67-dihe-in -65.77, -17.85 -61.14, -43.62 APE12-dist-out 14.7255 APE11-dist-in 11.397 APE10-dist-in 7.3403 APE9-dist-in 4.2516 None None CME159,CME252 XRAY 1.64 0.131 0.178 A 364.0 340.0 0 31 31 0 [[23, 311]] 1.0 8qr2 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR3A P63086 9 354 358.0 WNC:405 Type1 Inactive DFGin 7.2392 15.767 BLAminus -111.72, 158.63 66.9, 99.39 -105.45, 22.8 279.88, 80.76 -71.45, -20.97 in-in in 9.7836 Saltbr-in 2.9179 HRD-in -71.41, -51.22 75.55, 6.15 in-in-out SNCiio in-out ActLoopNT-in 2.7533 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -51.43, 150.97 APE9-dihe-na 60.18, 174.67 APE8-dihe-in -78.46, 135.82 APE8-rot-in 299.74 APE67-dihe-in -63.79, -18.52 -48.38, -52.85 APE12-dist-in 13.6335 APE11-dist-in 11.6857 APE10-dist-out 8.7477 APE9-dist-in 3.257 None None CME159,CME252 XRAY 1.65 0.145 0.189 A 364.0 346.0 0 31 31 0 [[23, 311]] 1.0 8qr3 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR4A P63086 9 354 358.0 WN8:403 Type1 Inactive DFGin 7.026 15.787 BLAminus -120.79, 162.9 63.51, 96.43 -106.96, 24.9 284.25, 77.14 -73.26, -20.35 in-in in 9.7539 Saltbr-in 2.7507 HRD-in -72.28, -52.65 72.34, 11.91 in-in-out SNCiio in-out ActLoopNT-in 2.7665 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -110.9, -34.47 APE9-dihe-na -68.4, 171.33 APE8-dihe-in -73.8, 132.91 APE8-rot-in 307.77 APE67-dihe-in -60.68, -16.14 -53.19, -56.89 APE12-dist-out 14.3632 APE11-dist-in 11.3081 APE10-dist-in 6.9082 APE9-dist-in 4.0824 None None CME159,CME252 XRAY 1.92 0.191 0.224 A 364.0 340.0 0 31 31 0 [[23, 311]] 1.0 8qr4 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR5A P63086 9 354 358.0 WMC:402 Type1 Inactive DFGin 7.0636 15.8269 BLAminus -112.33, 161.57 72.1, 92.3 -101.75, 27.09 284.62, 76.44 -72.23, -18.18 in-in in 9.9107 Saltbr-in 2.8918 HRD-in -73.83, -48.38 72.35, 3.86 in-in-out SNCiio in-out ActLoopNT-in 2.8141 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -102.57, -41.82 APE9-dihe-na -59.41, 159.7 APE8-dihe-in -55.08, 130.0 APE8-rot-in 313.78 APE67-dihe-in -64.89, -17.55 -56.57, -50.38 APE12-dist-out 14.6747 APE11-dist-in 11.3403 APE10-dist-in 7.3274 APE9-dist-in 4.2951 None None CME159,CME252 XRAY 1.6 0.141 0.188 A 364.0 342.0 0 31 31 0 [[23, 311]] 1.0 8qr5 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR6A P63086 9 354 358.0 WMN:406 Type1 Inactive DFGin 7.2128 16.0863 BLAminus -107.94, 154.41 70.42, 98.93 -106.03, 21.97 285.57, 80.57 -73.35, -18.04 out-in out 10.1118 Saltbr-in 2.6054 HRD-in -68.81, -51.2 72.85, 10.04 in-in-out SNCiio in-out ActLoopNT-in 2.7565 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -57.77, 146.92 APE9-dihe-na 67.75, -177.29 APE8-dihe-in -93.0, 139.82 APE8-rot-in 292.68 APE67-dihe-in -65.03, -17.98 -44.28, -53.83 APE12-dist-in 13.727 APE11-dist-in 11.6411 APE10-dist-out 8.9298 APE9-dist-in 3.2248 None None CME159,CME252 XRAY 1.65 0.155 0.199 A 364.0 346.0 0 31 31 0 [[23, 311]] 1.0 8qr6 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR7A P63086 9 357 358.0 WMI:405 Type1 Inactive DFGin 7.2446 15.7889 BLAminus -110.79, 160.7 66.46, 96.98 -104.77, 21.8 281.2, 80.4 -70.56, -19.87 in-in in 9.6724 Saltbr-in 2.8218 HRD-in -68.99, -49.95 71.83, 9.23 in-in-out SNCiio in-out ActLoopNT-in 2.8033 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -59.24, 151.05 APE9-dihe-na 62.57, 171.67 APE8-dihe-in -76.36, 134.64 APE8-rot-in 299.59 APE67-dihe-in -62.19, -19.6 -46.84, -55.69 APE12-dist-in 13.6365 APE11-dist-in 11.8605 APE10-dist-out 8.7016 APE9-dist-in 3.2713 None None CME159,CME252 XRAY 1.51 0.146 0.188 A 364.0 341.0 0 31 31 0 [[23, 311]] 1.0 8qr7 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR8A P63086 9 354 358.0 WN2:403 Type1 Inactive DFGin 7.1171 15.9549 BLAminus -106.94, 156.78 69.13, 99.72 -106.38, 24.87 286.33, 74.19 -68.77, -23.2 in-in in 9.8827 Saltbr-in 2.7663 HRD-in -71.77, -48.28 72.09, 6.42 in-in-out SNCiio in-out ActLoopNT-in 2.8302 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -89.24, 148.72 APE9-dihe-na 57.88, 155.99 APE8-dihe-in -47.44, 134.77 APE8-rot-in 307.51 APE67-dihe-in -60.43, -20.6 -50.3, -54.04 APE12-dist-in 13.3421 APE11-dist-in 11.4517 APE10-dist-out 8.6647 APE9-dist-in 3.3596 None None CME159,CME252 XRAY 1.61 0.158 0.2 A 364.0 342.0 0 31 31 0 [[23, 311]] 1.0 8qr8 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR9A P63086 9 354 358.0 WMX:407 Type1 Inactive DFGin 7.0376 16.0252 BLAminus -106.8, 150.63 74.72, 94.19 -98.08, 19.98 287.02, 79.69 -69.89, -19.87 out-in out 10.0191 Saltbr-in 3.2979 HRD-in -70.08, -52.13 75.82, 4.35 in-in-out SNCiio in-out ActLoopNT-in 2.7525 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -54.65, 151.23 APE9-dihe-na 56.4, 163.59 APE8-dihe-in -68.57, 140.2 APE8-rot-in 303.05 APE67-dihe-in -65.92, -15.94 -54.49, -52.24 APE12-dist-in 13.6041 APE11-dist-in 11.839 APE10-dist-out 8.7682 APE9-dist-in 3.2698 None None CME159,CME252 XRAY 1.94 0.18 0.222 A 364.0 346.0 0 31 31 0 [[23, 311]] 1.0 8qr9 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QRAA P63086 9 354 358.0 WM6:403 Type1 Inactive DFGin 6.9075 15.7961 BLAminus -118.02, 161.64 67.93, 95.61 -103.21, 22.49 286.51, 76.31 -69.0, -16.04 in-in in 9.7183 Saltbr-in 2.5782 HRD-in -72.56, -50.99 74.14, 4.54 in-in-out SNCiio in-out ActLoopNT-in 2.8003 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -55.96, 149.23 APE9-dihe-na 59.49, 149.86 APE8-dihe-in -31.13, 131.38 APE8-rot-in 308.8 APE67-dihe-in -64.8, -18.22 -54.49, -50.75 APE12-dist-in 13.3775 APE11-dist-in 11.5657 APE10-dist-out 8.7214 APE9-dist-in 3.3207 None None CME159,CME252 XRAY 1.55 0.144 0.182 A 364.0 341.0 0 31 31 0 [[23, 311]] 1.0 8qra Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QRBA P63086 9 356 358.0 WLZ:406 Type1 Inactive DFGin 7.1106 15.7814 BLAminus -127.57, 160.33 62.59, 99.91 -109.15, 27.72 282.94, 75.75 -73.21, -20.66 in-in in 9.9553 Saltbr-in 2.9813 HRD-in -72.73, -50.72 71.82, 13.14 in-in-out SNCiio in-out ActLoopNT-in 2.7851 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -49.82, 143.23 APE9-dihe-na 61.86, 160.49 APE8-dihe-in -54.61, 134.6 APE8-rot-in 304.07 APE67-dihe-in -61.8, -17.63 -47.98, -58.12 APE12-dist-in 13.5948 APE11-dist-in 11.5615 APE10-dist-out 8.7602 APE9-dist-in 3.4345 None None CME159 XRAY 1.51 0.178 0.209 A 364.0 348.0 0 31 31 0 [[23, 311]] 1.0 8qrb Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QRCA P63086 9 354 358.0 WMT:402 Type1 Inactive DFGin 6.7805 15.7581 BLAminus -123.41, 169.3 60.02, 91.76 -97.8, 33.64 285.09, 75.77 -62.73, -31.26 out-in out 10.1144 Saltbr-in 2.9344 HRD-in -73.97, -50.48 72.02, 10.48 in-in-out SNCiio in-out ActLoopNT-in 2.7474 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.01, -37.31 APE9-dihe-na -64.72, 166.95 APE8-dihe-in -66.38, 136.7 APE8-rot-in 311.84 APE67-dihe-in -61.95, -18.28 -62.38, -48.62 APE12-dist-out 14.3716 APE11-dist-in 11.1549 APE10-dist-in 6.9714 APE9-dist-in 4.2394 None None CME159,CME252 XRAY 1.69 0.151 0.198 A 364.0 337.0 0 31 31 0 [[23, 311]] 1.0 8qrc Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 2Z7LA P63086 16 355 358.0 S91:61001 Type1 Inactive DFGin 6.8008 16.4338 BLAminus -136.9, 170.79 66.29, 86.62 -103.07, 34.52 288.59, 65.29 -58.02, -43.27 out-out out 10.2385 Saltbr-out 4.5892 HRD-in -77.28, -55.92 74.77, 0.96 out-in-in SNCoii in-in ActLoopNT-in 2.7255 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -88.62, -49.81 APE9-dihe-na -40.28, 150.05 APE8-dihe-in -49.12, 125.58 APE8-rot-in 308.41 APE67-dihe-in -53.59, -24.0 -51.3, -52.67 APE12-dist-in 13.9992 APE11-dist-in 10.9277 APE10-dist-in 6.843 APE9-dist-in 4.1581 None None None XRAY 2.41 0.223 0.276 A 366.0 329.0 3 31 31 0 [[23, 311]] 1.0 2z7l Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 5KE0A P63086 16 355 358.0 6S9:401 Type1 Inactive DFGin 6.8311 15.0978 BLAminus -129.16, 176.97 69.35, 80.56 -97.81, 23.27 286.18, 69.95 -66.05, -22.44 in-in in 9.3068 Saltbr-in 2.7534 HRD-in -76.1, -51.61 73.82, 5.91 in-in-out SNCiio in-out ActLoopNT-in 2.7961 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -84.54, -37.3 APE9-dihe-na -71.22, 162.96 APE8-dihe-in -52.88, 123.68 APE8-rot-in 310.69 APE67-dihe-in -61.3, -20.37 -50.36, -53.16 APE12-dist-out 14.4313 APE11-dist-in 11.1643 APE10-dist-in 6.8597 APE9-dist-in 4.3913 None None None XRAY 1.68 0.169 0.191 A 366.0 340.0 0 31 31 0 [[23, 311]] 1.0 5ke0 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 5U6IA P63086 16 355 358.0 81Y:401 Type1 Inactive DFGin 6.8248 14.8408 BLAminus -131.29, 174.92 68.74, 80.64 -97.46, 21.9 283.5, 71.75 -59.58, -27.64 in-in in 9.2022 Saltbr-in 2.7642 HRD-in -76.03, -52.9 75.2, 3.34 in-in-out SNCiio in-out ActLoopNT-in 2.8153 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -88.65, -39.48 APE9-dihe-na -69.18, 161.4 APE8-dihe-in -50.56, 122.76 APE8-rot-in 310.75 APE67-dihe-in -61.33, -21.23 -51.09, -50.17 APE12-dist-out 14.4865 APE11-dist-in 11.167 APE10-dist-in 6.9764 APE9-dist-in 4.4139 None None None XRAY 1.69 0.169 0.186 A 366.0 339.0 1 31 31 0 [[23, 311]] 1.0 5u6i Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 5HD7A P63086 9 355 358.0 38Z:401 Type1 Inactive DFGin 6.6169 16.3974 BLAminus -128.09, 178.37 68.56, 85.26 -107.06, 21.62 285.69, 78.69 -70.28, -12.54 in-in in 9.5452 Saltbr-in 2.6662 HRD-in -71.35, -50.28 70.7, 8.65 in-in-out SNCiio in-out ActLoopNT-in 2.7976 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.73, -37.18 APE9-dihe-na -62.95, 158.16 APE8-dihe-in -50.32, 124.93 APE8-rot-in 314.5 APE67-dihe-in -63.38, -19.4 -51.82, -51.63 APE12-dist-out 14.404 APE11-dist-in 11.122 APE10-dist-in 7.2822 APE9-dist-in 4.4034 G167D None None XRAY 1.69 0.182 0.207 A 365.0 347.0 0 31 31 0 [[23, 311]] 1.0 5hd7 Rattus norvegicus CMGC_MAPK1_RAT CMGC 8e-84 287.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4N4SA P63086 8 356 358.0 2H1:401 Type1.5_Back Inactive DFGin 6.8159 16.7081 BLAminus -116.12, 166.7 66.69, 89.49 -99.58, 27.86 294.96, 80.31 -63.14, -30.1 out-out out 10.4441 Saltbr-out 7.6209 HRD-in -75.34, -53.11 71.98, 8.82 out-in-out SNCoio in-out ActLoopNT-in 2.8038 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -140.29, 155.03 APE9-dihe-na -61.58, -38.32 APE8-dihe-in -149.07, 139.77 APE8-rot-out 171.6 APE67-dihe-in -66.78, -20.12 -102.79, 12.94 APE12-dist-in 9.0893 APE11-dist-in 12.189 APE10-dist-out 8.994 APE9-dist-out 10.9723 Q103A,C164L None None XRAY 2.2 0.223 0.253 A 359.0 342.0 7 31 24 7 [[23, 311]] 1.0 4n4s Rattus norvegicus CMGC_MAPK1_RAT CMGC 5e-85 291.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4N4SB P63086 8 356 358.0 2H1:401 Type1.5_Back Inactive DFGin 6.722 16.8898 BLAminus -117.75, 167.45 66.96, 88.97 -98.01, 25.84 293.93, 90.09 -63.54, -29.88 out-out out 10.5039 Saltbr-out 7.8397 HRD-in -75.26, -52.69 71.86, 7.64 out-in-out SNCoio in-out ActLoopNT-in 2.8064 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 179.95 APE8-dihe-in -141.22, 138.76 APE8-rot-out 169.5 APE67-dihe-in -67.64, -21.96 -101.08, 11.3 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.3672 Q103A,C164L None None XRAY 2.2 0.223 0.253 B 359.0 337.0 12 31 19 12 [[23, 311]] 1.0 4n4s Rattus norvegicus CMGC_MAPK1_RAT CMGC 5e-85 291.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XOZA P63086 8 354 358.0 620:401 Type1.5_Front Inactive DFGin 7.0338 17.1796 BLAminus -134.11, -179.17 64.03, 75.89 -98.44, 22.92 284.72, 79.08 -64.36, -27.3 out-out out 10.9544 Saltbr-out 7.0581 HRD-in -69.47, -52.23 72.29, -1.02 out-in-out SNCoio in-out ActLoopNT-in 2.8283 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -105.18, -18.66 APE9-dihe-na -75.46, 166.86 APE8-dihe-in -66.79, 127.73 APE8-rot-in 308.37 APE67-dihe-in -59.61, -18.58 -53.08, -50.65 APE12-dist-out 14.394 APE11-dist-in 11.0734 APE10-dist-in 7.3638 APE9-dist-in 4.4737 None None CME159 XRAY 1.95 0.147 0.188 A 351.0 342.0 0 31 31 0 [[23, 311]] 1.0 4xoz Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4QYYA P63086 13 353 358.0 3G7:401 Type1.5_Front Inactive DFGin 6.7251 16.3904 BLAminus -132.71, 173.31 70.0, 86.57 -103.46, 23.97 286.71, 76.13 -60.77, -27.68 in-in in 9.5365 Saltbr-in 2.6005 HRD-in -74.52, -50.72 73.19, 8.77 in-in-out SNCiio in-out ActLoopNT-in 2.7846 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.27, -36.79 APE9-dihe-na -64.89, 158.32 APE8-dihe-in -46.41, 120.56 APE8-rot-in 314.36 APE67-dihe-in -60.78, -19.5 -50.53, -52.6 APE12-dist-out 14.3811 APE11-dist-in 11.1066 APE10-dist-in 7.3001 APE9-dist-in 4.4257 None None None XRAY 1.65 0.229 0.259 A 365.0 337.0 0 31 31 0 [[23, 311]] 1.0 4qyy Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 5HD4A P63086 9 355 358.0 38Z:401 Type1.5_Front Inactive DFGin 6.7617 16.3963 BLAminus -132.15, 171.71 72.04, 89.95 -105.49, 25.28 288.89, 74.15 -62.94, -29.6 in-in in 9.6091 Saltbr-in 2.6511 HRD-in -73.9, -52.49 73.6, 6.76 in-in-out SNCiio in-out ActLoopNT-in 2.7885 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.81, -40.96 APE9-dihe-na -60.91, 155.22 APE8-dihe-in -46.4, 120.98 APE8-rot-in 315.89 APE67-dihe-in -62.79, -18.63 -49.8, -50.9 APE12-dist-out 14.32 APE11-dist-in 11.0677 APE10-dist-in 7.1595 APE9-dist-in 4.4363 None None None XRAY 1.45 0.177 0.199 A 365.0 347.0 0 31 31 0 [[23, 311]] 1.0 5hd4 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6CPWA P63086 16 355 358.0 F8V:403 Type1.5_Front Inactive DFGin 6.7287 16.4334 BLAminus -131.65, 172.57 66.32, 87.15 -102.19, 23.21 287.0, 74.02 -60.73, -27.83 in-in in 9.7402 Saltbr-in 2.6096 HRD-in -72.55, -51.86 72.75, 5.47 in-in-out SNCiio in-out ActLoopNT-in 2.82 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.83, -38.85 APE9-dihe-na -58.06, 150.18 APE8-dihe-in -41.46, 122.36 APE8-rot-in 313.47 APE67-dihe-in -62.43, -17.55 -55.27, -49.2 APE12-dist-out 14.4183 APE11-dist-in 11.1119 APE10-dist-in 7.425 APE9-dist-in 4.4034 None None None XRAY 1.85 0.19 0.224 A 366.0 328.0 5 31 31 0 [[23, 311]] 1.0 6cpw Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6DCGA P63086 16 354 358.0 G67:403 Type1.5_Front Inactive DFGin 6.7381 16.3113 BLAminus -128.96, 170.91 70.91, 87.53 -102.77, 23.72 285.91, 75.71 -65.7, -26.65 in-in in 9.5778 Saltbr-in 2.5866 HRD-in -74.26, -51.41 73.54, 7.44 in-in-out SNCiio in-out ActLoopNT-in 2.8149 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.1, -35.07 APE9-dihe-na -65.64, 158.57 APE8-dihe-in -47.89, 121.75 APE8-rot-in 313.14 APE67-dihe-in -64.08, -17.48 -49.3, -51.53 APE12-dist-out 14.4524 APE11-dist-in 11.1167 APE10-dist-in 7.306 APE9-dist-in 4.3726 None None None XRAY 1.45 0.178 0.199 A 366.0 326.0 5 31 31 0 [[23, 311]] 1.0 6dcg Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FJZA P63086 9 354 358.0 DKW:402 Type1 Inactive DFGin 6.6634 16.4202 None -134.8, -179.27 82.46, -86.27 66.98, 18.08 291.18, 83.08 -68.21, -20.47 in-in in 9.2842 Saltbr-in 2.7213 HRD-in -71.29, -49.89 75.9, -0.67 in-in-out SNCiio in-out ActLoopNT-in 2.7431 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.27, -45.48 APE9-dihe-na -54.12, 158.83 APE8-dihe-in -55.9, 129.11 APE8-rot-in 307.1 APE67-dihe-in -60.37, -17.39 -59.77, -49.92 APE12-dist-out 14.2719 APE11-dist-in 11.2255 APE10-dist-in 7.301 APE9-dist-in 4.4081 None None CME159 XRAY 1.864 0.174 0.207 A 364.0 346.0 0 31 31 0 [[23, 311]] 1.0 6fjz Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4I5HA P63086 9 356 358.0 G17:401 Type2 Inactive DFGout 16.7361 7.9906 None -129.89, 156.41 -129.44, 98.8 -58.76, -39.89 187.16, 88.85 121.71, -175.9 in-in in 8.6475 Saltbr-in 2.6758 HRD-in -71.0, -49.44 78.62, -12.56 in-out-out SNCioo out-out ActLoopNT-out 18.2558 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -68.91, 157.99 APE9-dihe-na -71.89, 135.07 APE8-dihe-in -136.31, 148.41 APE8-rot-out 167.99 APE67-dihe-in -62.3, -21.48 -106.14, 1.26 APE12-dist-in 13.4361 APE11-dist-in 8.7287 APE10-dist-out 10.207 APE9-dist-out 9.9537 Q103A,C164L None None XRAY 1.9 0.22 0.257 A 359.0 335.0 7 31 24 7 [[23, 311]] 1.0 4i5h Rattus norvegicus CMGC_MAPK1_RAT CMGC 5e-85 291.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6RFOA P63086 12 355 358.0 No_ligand No_ligand Inactive None 999.0 999.0 None 999.0, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 in-out in 9.7959 Saltbr-out 8.4645 HRD-in -69.04, -52.69 71.19, -0.59 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.7 0.16 0.219 A 372.0 292.0 15 25 19 6 [[23, 311]] 1.0 6rfo Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.1e-85 293.4 1.0 301.0 301.0 167 168 169 171 173 52 69 73 144 146 145 147.0 208 192 187 186 185 184 183 182 181 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3C9WA P63086 6 354 358.0 HMY:1 Type1 None DFGin 6.9994 15.702 BLAminus -123.81, 173.38 50.82, 89.77 -103.35, 17.03 287.88, 69.21 -57.05, -26.18 in-in in 9.643 Saltbr-in 2.6942 HRD-in -68.6, -50.76 75.06, -2.41 in-in-none SNCiin in-none ActLoopNT-in 2.7402 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 147.03 APE8-rot-in 303.8 APE67-dihe-in -65.62, -21.36 -55.58, -26.02 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.197 0.274 A 357.0 336.0 13 31 18 13 [[23, 311]] 1.0 3c9w Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1

CMGC_MAPK1 (Mitogen-activated protein kinase 1)

Total number of chains: 81
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 78 96.3% 4S32A
DFGin None 1 1.2% 6FJZA
DFGout None 1 1.2% 4I5HA
None None 1 1.2% 6RFOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAPK1 MK01_RAT 3ZUVA P63086 3 358 358.0 No_ligand No_ligand Active DFGin 6.8481 16.0922 BLAminus -133.65, -165.63 47.31, 79.28 -98.88, 11.99 277.19, 74.23 -55.55, -32.12 out-in out 10.0059 Saltbr-in 2.8055 HRD-in -79.74, -48.77 75.23, 9.95 in-in-in SNCiii in-in ActLoopNT-in 2.8269 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -118.75, 171.21 APE9-dihe-na 66.75, 153.3 APE8-dihe-in -75.0, 135.66 APE8-rot-in 294.16 APE67-dihe-in -61.53, -6.75 -41.14, -56.91 APE12-dist-in 13.0103 APE11-dist-in 11.0438 APE10-dist-in 6.9795 APE9-dist-in 2.9275 None TPO183,PTR185 TPO183,PTR185 XRAY 2.72 0.178 0.23 A 364.0 356.0 0 31 31 0 [[23, 311]] 1.0 3zuv Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3ZUVC P63086 3 358 358.0 No_ligand No_ligand Active DFGin 6.8584 15.9524 BLAminus -132.51, -167.35 55.02, 75.95 -92.55, 22.14 285.34, 69.26 -63.7, -35.45 out-in out 10.2463 Saltbr-in 3.004 HRD-in -69.99, -55.08 76.64, 11.33 in-in-in SNCiii in-in ActLoopNT-in 2.952 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.97, 163.62 APE9-dihe-na 66.94, 113.14 APE8-dihe-in -36.38, 138.15 APE8-rot-in 306.69 APE67-dihe-in -65.92, -14.38 -40.78, -57.92 APE12-dist-in 12.8947 APE11-dist-in 10.7853 APE10-dist-in 7.0763 APE9-dist-in 3.0808 None TPO183,PTR185 TPO183,PTR185 XRAY 2.72 0.178 0.23 C 364.0 356.0 0 31 31 0 [[23, 311]] 1.0 3zuv Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 2ERKA P63086 6 358 358.0 No_ligand No_ligand Active DFGin 6.8812 16.1828 BLAminus -131.49, -174.52 51.55, 76.13 -93.95, 24.88 283.85, 70.54 -64.25, -32.22 out-in out 10.2306 Saltbr-in 3.3951 HRD-in -66.75, -47.09 67.93, 5.7 in-in-in SNCiii in-in ActLoopNT-in 2.736 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.33, 162.31 APE9-dihe-na 70.29, 158.85 APE8-dihe-in -78.8, 134.95 APE8-rot-in 293.27 APE67-dihe-in -57.35, -16.08 -38.3, -60.44 APE12-dist-in 12.7429 APE11-dist-in 10.712 APE10-dist-in 6.772 APE9-dist-in 2.9365 None TPO183,PTR185 TPO183,PTR185 XRAY 2.4 0.192 0.264 A 365.0 353.0 0 31 31 0 [[23, 311]] 1.0 2erk Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6OPKA P63086 9 354 358.0 390:401 Type1 Active DFGin 6.6542 14.7552 BLAminus -124.25, -173.22 49.18, 87.88 -102.56, 22.49 282.63, 69.81 -58.83, -33.74 in-in in 9.2501 Saltbr-in 2.6489 HRD-in -78.1, -60.74 80.93, 7.16 in-in-in SNCiii in-in ActLoopNT-in 2.9386 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -91.49, 173.12 APE9-dihe-na 65.2, 169.84 APE8-dihe-in -91.59, 138.21 APE8-rot-in 292.7 APE67-dihe-in -63.57, -14.22 -44.54, -55.14 APE12-dist-in 12.7505 APE11-dist-in 11.1804 APE10-dist-in 6.8439 APE9-dist-in 2.9753 None TPO183,PTR185 TPO183,PTR185 XRAY 2.54 0.196 0.241 A 352.0 346.0 0 31 31 0 [[23, 311]] 1.0 6opk Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4S33A P63086 4 355 358.0 ANP:401 ATPlike Inactive DFGin 6.7431 16.086 BLAminus -130.86, 178.79 71.13, 76.62 -98.92, 24.03 286.96, 71.68 -62.72, -21.16 in-in in 9.6873 Saltbr-in 2.6802 HRD-in -72.9, -49.96 78.15, -0.96 in-in-out SNCiio in-out ActLoopNT-in 2.8648 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -104.41, -43.84 APE9-dihe-na -64.59, 164.35 APE8-dihe-in -56.21, 123.2 APE8-rot-in 315.9 APE67-dihe-in -61.37, -21.31 -48.55, -49.93 APE12-dist-out 14.7318 APE11-dist-in 11.3056 APE10-dist-in 7.3108 APE9-dist-in 4.4832 R65S None None XRAY 1.48 0.199 0.239 A 358.0 347.0 0 31 31 0 [[23, 311]] 1.0 4s33 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.5e-85 293.0 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4S32A P63086 4 354 358.0 ANP:401 ATPlike Inactive DFGin 6.6461 16.3353 BLAminus -133.92, 176.75 65.37, 79.23 -97.7, 23.57 287.97, 74.34 -66.64, -19.31 in-out in 9.8686 Saltbr-out 3.654 HRD-in -75.76, -45.6 71.68, 4.61 out-in-out SNCoio in-out ActLoopNT-in 2.8278 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.88, -32.08 APE9-dihe-na -65.5, 159.94 APE8-dihe-in -53.88, 129.7 APE8-rot-in 310.08 APE67-dihe-in -61.98, -20.6 -58.72, -45.65 APE12-dist-out 14.5455 APE11-dist-in 11.219 APE10-dist-in 7.4905 APE9-dist-in 4.4333 None None None XRAY 1.34 0.199 0.231 A 358.0 346.0 0 31 31 0 [[23, 311]] 1.0 4s32 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4GT3A P63086 9 356 358.0 ATP:402 ATPlike Inactive DFGin 6.7027 16.1444 BLAminus -134.54, -176.44 66.94, 76.71 -104.84, 22.9 282.81, 76.31 -55.64, -34.0 in-none in 9.8171 Saltbr-none 999.0 HRD-in -69.89, -50.79 79.79, -14.59 none-in-out SNCnio in-out ActLoopNT-in 2.7761 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -105.46, -44.03 APE9-dihe-na -70.04, 169.29 APE8-dihe-in -70.71, 123.51 APE8-rot-in 309.48 APE67-dihe-in -61.98, -17.54 -56.41, -47.97 APE12-dist-out 14.2886 APE11-dist-in 11.0026 APE10-dist-in 6.7399 APE9-dist-in 4.4218 None None CME159 XRAY 1.68 0.168 0.2 A 364.0 348.0 0 31 31 0 [[23, 311]] 1.0 4gt3 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4GVAA P63086 11 356 358.0 ADP:401 ATPlike Inactive DFGin 6.7023 16.7688 BLAminus -137.11, 178.59 63.89, 77.38 -94.14, 25.17 286.58, 79.57 -59.17, -35.22 out-out out 10.4922 Saltbr-out 6.5214 HRD-in -67.64, -55.15 72.72, 9.25 out-in-in SNCoii in-in ActLoopNT-in 2.8301 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -101.68, -13.3 APE9-dihe-na -77.88, 161.53 APE8-dihe-in -56.04, 126.28 APE8-rot-in 320.84 APE67-dihe-in -66.77, -13.08 -47.2, -54.23 APE12-dist-in 13.8449 APE11-dist-in 11.0504 APE10-dist-in 7.1482 APE9-dist-in 4.1983 None None CME159 XRAY 1.83 0.191 0.241 A 364.0 346.0 0 31 31 0 [[23, 311]] 1.0 4gva Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 7UGBA P63086 9 354 358.0 ANP:60401 ATPlike Inactive DFGin 6.8438 15.6136 BLAminus -132.85, -175.34 66.19, 68.8 -95.15, 22.62 283.13, 71.04 -65.04, -17.4 in-in in 9.2984 Saltbr-in 3.0947 HRD-in -74.44, -45.95 75.99, -7.39 in-in-out SNCiio in-out ActLoopNT-in 2.7599 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -141.06, 152.87 APE9-dihe-na -67.4, -32.8 APE8-dihe-in -151.29, 138.48 APE8-rot-out 186.29 APE67-dihe-in -67.11, -12.06 -109.33, 7.55 APE12-dist-in 8.5189 APE11-dist-in 12.1904 APE10-dist-out 9.145 APE9-dist-out 11.3673 None None None XRAY 1.9 0.181 0.228 A 380.0 333.0 9 31 22 9 [[23, 311]] 1.0 7ugb Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.6e-85 292.9 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4S34A P63086 4 354 358.0 ANP:402 ATPlike Inactive DFGin 6.9305 15.9209 BLAminus -141.95, 172.44 70.56, 81.84 -99.71, 28.41 294.26, 76.1 -60.19, -38.53 in-out in 9.8624 Saltbr-out 3.6484 HRD-in -79.44, -51.86 83.9, -4.35 out-in-out SNCoio in-out ActLoopNT-in 2.8808 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -91.12, -42.94 APE9-dihe-na -58.97, 168.13 APE8-dihe-in -69.02, 123.37 APE8-rot-in 313.04 APE67-dihe-in -67.86, -24.53 -49.65, -45.75 APE12-dist-out 14.8428 APE11-dist-in 11.3273 APE10-dist-in 7.2767 APE9-dist-in 4.4811 I84A None None XRAY 2.5 0.182 0.255 A 358.0 343.0 0 31 31 0 [[23, 311]] 1.0 4s34 Rattus norvegicus CMGC_MAPK1_RAT CMGC 2.9e-85 292.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 1GOLA P63086 2 358 358.0 ATP:581 ATPlike Inactive DFGin 6.8401 16.5086 BLAminus -138.32, 175.35 71.89, 79.82 -106.15, 29.68 287.28, 71.38 -70.4, -19.75 out-none out 10.4077 Saltbr-none 999.0 HRD-in -68.54, -52.86 75.92, 1.19 none-in-out SNCnio in-out ActLoopNT-in 2.8991 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.2, -24.36 APE9-dihe-na -62.06, 164.48 APE8-dihe-in -61.17, 119.13 APE8-rot-in 302.33 APE67-dihe-in -53.15, -25.45 -41.46, -58.53 APE12-dist-out 14.3386 APE11-dist-in 11.2075 APE10-dist-in 7.401 APE9-dist-in 4.2815 K52R None None XRAY 2.8 999.0 999.0 A 364.0 357.0 0 31 31 0 [[23, 311]] 1.0 1gol Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-84 289.8 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8RQVA P63086 4 354 358.0 ANP:501 ATPlike Inactive DFGin 6.9036 16.0694 BLAminus -129.6, -175.7 63.15, 70.39 -89.62, 28.98 289.85, 76.4 -67.34, -38.13 in-out in 9.7114 Saltbr-out 4.2746 HRD-in -67.81, -55.04 72.76, 2.89 out-in-out SNCoio in-out ActLoopNT-in 2.7655 ActLoopCT-out nonTYR APEdihe_aaini APEdist_oiii APE10-dihe-na -100.88, -30.73 APE9-dihe-na -77.54, 159.87 APE8-dihe-in -50.38, 124.93 APE8-rot-none 999.0 APE67-dihe-in -63.77, -19.96 -54.06, -49.39 APE12-dist-out 14.154 APE11-dist-in 10.7528 APE10-dist-in 7.0254 APE9-dist-in 4.3496 T188A None None XRAY 2.19 0.22 0.268 A 365.0 346.0 0 31 31 0 [[23, 311]] 1.0 8rqv Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.1e-84 290.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8RQXA P63086 4 353 358.0 ANP:501 ATPlike Inactive DFGin 6.7525 15.7711 BLAminus -131.54, -179.98 70.52, 77.44 -96.49, 23.47 286.75, 76.4 -63.49, -27.29 in-out in 9.2826 Saltbr-out 4.0303 HRD-in -71.44, -55.38 74.63, 0.71 out-in-out SNCoio in-out ActLoopNT-in 2.8623 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oiii APE10-dihe-na -102.41, -41.91 APE9-dihe-na -63.48, 155.78 APE8-dihe-in -53.17, 123.33 APE8-rot-na 196.55 APE67-dihe-in -71.02, -16.45 -50.75, -40.77 APE12-dist-out 14.2124 APE11-dist-in 10.7678 APE10-dist-in 6.9866 APE9-dist-in 4.4522 R65S,T188D None None XRAY 1.7 0.199 0.231 A 365.0 344.0 0 31 31 0 [[23, 311]] 1.0 8rqx Rattus norvegicus CMGC_MAPK1_RAT CMGC 3.4e-84 288.6 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8RQWA P63086 4 354 358.0 ANP:501 ATPlike Inactive DFGin 6.8494 16.0159 BLAminus -129.63, 178.83 67.86, 79.37 -97.6, 20.5 285.29, 78.65 -60.41, -30.78 in-out in 9.7711 Saltbr-out 4.0654 HRD-in -69.59, -52.69 70.29, 6.23 out-in-out SNCoio in-out ActLoopNT-in 2.8367 ActLoopCT-out nonTYR APEdihe_aaiai APEdist_oiii APE10-dihe-na -111.03, -43.37 APE9-dihe-na -66.74, 156.04 APE8-dihe-in -59.11, 129.69 APE8-rot-na 165.64 APE67-dihe-in -63.23, -21.3 -54.35, -46.88 APE12-dist-out 14.6367 APE11-dist-in 10.9228 APE10-dist-in 6.9125 APE9-dist-in 4.2589 T188E None None XRAY 1.8 0.198 0.231 A 365.0 344.0 0 31 31 0 [[23, 311]] 1.0 8rqw Rattus norvegicus CMGC_MAPK1_RAT CMGC 3e-84 288.8 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6RFPA P63086 3 353 358.0 No_ligand No_ligand Inactive DFGin 6.7509 16.1665 BLAminus -127.92, 177.69 70.53, 82.36 -102.39, 18.51 287.59, 77.75 -57.77, -32.64 out-out out 10.0794 Saltbr-out 4.7547 HRD-in -77.75, -51.22 73.85, 1.99 out-in-in SNCoii in-in ActLoopNT-in 2.8433 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -101.61, -31.13 APE9-dihe-na -71.66, 165.31 APE8-dihe-in -63.21, 127.2 APE8-rot-in 308.34 APE67-dihe-in -65.57, -18.65 -54.13, -47.49 APE12-dist-in 13.9606 APE11-dist-in 10.9198 APE10-dist-in 7.1257 APE9-dist-in 4.3855 K229T,H230D,Y231H None None XRAY 1.74 0.147 0.197 A 378.0 337.0 4 31 31 0 [[23, 311]] 1.0 6rfp Rattus norvegicus CMGC_MAPK1_RAT CMGC 9.2e-86 293.7 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4S2ZA P63086 4 354 358.0 No_ligand No_ligand Inactive DFGin 6.7839 16.4902 BLAminus -133.04, 177.08 65.56, 78.71 -98.61, 27.52 290.68, 72.8 -66.65, -19.57 out-out out 10.3409 Saltbr-out 4.8007 HRD-in -72.43, -50.18 77.78, -1.73 out-in-out SNCoio in-out ActLoopNT-in 2.872 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.81, -37.9 APE9-dihe-na -64.1, 168.33 APE8-dihe-in -63.86, 128.05 APE8-rot-in 314.07 APE67-dihe-in -68.36, -13.94 -53.81, -48.77 APE12-dist-out 14.5792 APE11-dist-in 11.337 APE10-dist-in 7.5883 APE9-dist-in 4.5558 R65S None None XRAY 1.48 0.197 0.221 A 358.0 346.0 0 31 31 0 [[23, 311]] 1.0 4s2z Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.5e-85 293.0 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3R63A P63086 4 358 358.0 No_ligand No_ligand Inactive DFGin 6.8522 16.5941 BLAminus -131.22, -176.1 59.55, 77.84 -95.49, 24.21 286.96, 74.66 -59.37, -28.63 out-out out 10.3683 Saltbr-out 4.5325 HRD-in -72.03, -51.46 73.36, 2.63 out-in-out SNCoio in-out ActLoopNT-in 2.7654 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.69, -33.24 APE9-dihe-na -61.13, 151.44 APE8-dihe-in -42.74, 120.57 APE8-rot-in 313.17 APE67-dihe-in -67.39, -15.26 -50.0, -47.49 APE12-dist-out 14.4449 APE11-dist-in 11.1527 APE10-dist-in 7.3862 APE9-dist-in 4.3397 S246E None None XRAY 1.7 0.25 0.245 A 358.0 347.0 0 31 31 0 [[23, 311]] 1.0 3r63 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6OT6A P63086 9 356 358.0 No_ligand No_ligand Inactive DFGin 6.8401 16.5762 BLAminus -134.12, 179.02 66.48, 79.62 -101.27, 25.26 285.01, 75.77 -68.57, -21.35 out-out out 10.4268 Saltbr-out 6.2293 HRD-in -73.06, -51.9 73.75, 5.33 out-in-out SNCoio in-out ActLoopNT-in 2.729 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -101.44, -35.59 APE9-dihe-na -68.78, 163.48 APE8-dihe-in -61.41, 130.61 APE8-rot-in 309.72 APE67-dihe-in -66.07, -15.96 -59.12, -46.86 APE12-dist-out 14.5315 APE11-dist-in 11.13 APE10-dist-in 7.0961 APE9-dist-in 4.3014 D319N None None XRAY 1.65 0.17 0.201 A 358.0 346.0 0 31 31 0 [[23, 311]] 1.0 6ot6 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6OTSA P63086 7 356 358.0 No_ligand No_ligand Inactive DFGin 6.8308 16.1309 BLAminus -142.48, -172.73 60.21, 66.17 -97.08, 29.42 286.38, 75.36 -63.96, -41.03 out-in out 10.0789 Saltbr-in 3.5058 HRD-in -68.89, -50.67 70.41, 16.9 in-in-out SNCiio in-out ActLoopNT-in 2.7056 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_iioo APE10-dihe-na -143.1, 143.87 APE9-dihe-na -72.43, 115.64 APE8-dihe-out 56.21, 66.19 APE8-rot-out 79.9 APE67-dihe-out -71.29, -45.65 -77.68, 52.22 APE12-dist-in 7.2799 APE11-dist-in 11.6817 APE10-dist-out 8.8259 APE9-dist-out 11.0575 E320K None None XRAY 2.1 0.233 0.264 A 358.0 324.0 18 31 21 10 [[23, 311]] 1.0 6ots Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3O71A P63086 9 354 358.0 No_ligand No_ligand Inactive DFGin 6.8667 16.319 BLAminus -130.16, -179.56 58.84, 79.71 -96.83, 24.07 291.46, 76.59 -55.21, -31.57 in-out in 9.7287 Saltbr-out 4.0364 HRD-in -72.55, -51.65 77.3, -10.89 out-in-out SNCoio in-out ActLoopNT-in 2.7607 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooo APE10-dihe-na -87.87, 106.02 APE9-dihe-na -161.8, 155.6 APE8-dihe-in -53.25, 130.85 APE8-rot-in 321.28 APE67-dihe-in -65.84, -21.99 -102.05, -4.52 APE12-dist-in 11.0319 APE11-dist-out 7.246 APE10-dist-out 11.6636 APE9-dist-out 8.3598 None None None XRAY 1.95 0.201 0.24 A 358.0 340.0 6 31 26 5 [[23, 311]] 1.0 3o71 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4S31A P63086 4 355 358.0 No_ligand No_ligand Inactive DFGin 6.7729 16.4456 BLAminus -134.85, 175.69 67.38, 78.88 -97.91, 23.78 289.36, 71.89 -62.99, -24.05 out-out out 10.3711 Saltbr-out 4.3622 HRD-in -74.32, -51.14 74.9, 4.48 out-in-out SNCoio in-out ActLoopNT-in 2.8196 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -97.1, -38.05 APE9-dihe-na -61.18, 155.71 APE8-dihe-in -48.46, 125.56 APE8-rot-in 312.04 APE67-dihe-in -65.39, -17.68 -54.91, -48.02 APE12-dist-out 14.5533 APE11-dist-in 11.0746 APE10-dist-in 7.2421 APE9-dist-in 4.4141 None None None XRAY 1.45 0.211 0.24 A 358.0 347.0 0 31 31 0 [[23, 311]] 1.0 4s31 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 2FYSA P63086 8 356 358.0 No_ligand No_ligand Inactive DFGin 6.6376 16.4772 BLAminus -122.06, 169.63 25.05, 117.45 -113.18, 29.88 284.71, 61.81 -68.75, -32.78 in-out in 9.2572 Saltbr-out 4.193 HRD-in -87.12, -28.64 57.99, -13.75 out-in-out SNCoio in-out ActLoopNT-in 2.6633 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -134.87, 136.79 APE9-dihe-na -45.76, -39.06 APE8-dihe-in -148.7, 156.44 APE8-rot-out 49.9 APE67-dihe-in -64.46, -8.42 -128.65, 6.84 APE12-dist-in 9.1664 APE11-dist-in 12.3683 APE10-dist-out 9.0179 APE9-dist-out 11.2353 None None None XRAY 2.5 0.174 0.266 A 364.0 348.0 1 31 31 0 [[23, 311]] 1.0 2fys Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 2FYSB P63086 8 357 358.0 No_ligand No_ligand Inactive DFGin 6.7764 16.5493 BLAminus -141.27, -177.57 59.65, 89.49 -109.14, 28.54 291.65, 71.85 -72.29, -17.15 in-out in 9.7742 Saltbr-out 4.122 HRD-in -84.25, -43.16 67.41, 9.34 out-in-out SNCoio in-out ActLoopNT-in 2.7291 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -127.69, 133.42 APE9-dihe-na -104.82, 121.89 APE8-dihe-out 70.19, 135.55 APE8-rot-in 303.39 APE67-dihe-in -51.64, -21.24 -129.5, -2.74 APE12-dist-in 10.3843 APE11-dist-in 11.5524 APE10-dist-out 10.8576 APE9-dist-out 10.1251 None None None XRAY 2.5 0.174 0.266 B 364.0 338.0 8 31 23 8 [[23, 311]] 1.0 2fys Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4GSBA P63086 9 356 358.0 No_ligand No_ligand Inactive DFGin 6.7982 16.4904 BLAminus -130.79, 179.48 65.24, 78.76 -98.76, 20.67 284.56, 81.69 -61.23, -26.31 out-out out 10.0051 Saltbr-out 4.3408 HRD-in -72.92, -50.84 79.12, -10.47 out-in-out SNCoio in-out ActLoopNT-in 2.8065 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.36, -33.55 APE9-dihe-na -66.1, 151.89 APE8-dihe-in -42.86, 125.19 APE8-rot-in 317.67 APE67-dihe-in -64.3, -11.6 -62.99, -45.18 APE12-dist-out 14.531 APE11-dist-in 11.1906 APE10-dist-in 7.1304 APE9-dist-in 4.4396 None None CSO63,CME159 XRAY 1.8 0.156 0.199 A 364.0 345.0 3 31 31 0 [[23, 311]] 1.0 4gsb Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 5UMOA P63086 4 354 358.0 No_ligand No_ligand Inactive DFGin 6.9348 16.8433 BLAminus -127.41, 175.69 68.44, 77.39 -96.39, 28.52 286.86, 76.16 -71.36, -25.98 out-out out 10.5225 Saltbr-out 4.4515 HRD-in -72.01, -53.37 77.59, -11.41 out-in-out SNCoio in-out ActLoopNT-in 2.8653 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -93.31, -19.33 APE9-dihe-na -84.58, 165.69 APE8-dihe-in -65.22, 124.13 APE8-rot-in 312.49 APE67-dihe-in -65.69, -19.61 -54.99, -44.8 APE12-dist-out 14.5665 APE11-dist-in 11.2645 APE10-dist-in 7.5201 APE9-dist-in 4.8408 None None None XRAY 2.26 0.15 0.202 A 364.0 347.0 0 31 31 0 [[23, 311]] 1.0 5umo Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3ZU7A P63086 10 353 358.0 No_ligand No_ligand Inactive DFGin 6.7401 16.3406 BLAminus -124.79, 170.31 90.39, 80.99 -109.74, 30.8 288.45, 79.95 -70.99, -23.15 in-out in 9.7404 Saltbr-out 4.4631 HRD-in -72.24, -47.27 72.88, -7.81 out-in-out SNCoio in-out ActLoopNT-in 2.7051 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioo APE10-dihe-na -83.58, -18.35 APE9-dihe-na -93.42, 177.58 APE8-dihe-in -63.85, 148.62 APE8-rot-in 338.25 APE67-dihe-in -61.31, -19.32 -107.88, 5.19 APE12-dist-out 6.9469 APE11-dist-in 12.2123 APE10-dist-out 13.6862 APE9-dist-out 10.5597 None None None XRAY 1.97 0.221 0.269 A 365.0 344.0 0 31 31 0 [[23, 311]] 1.0 3zu7 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 2GPHA P63086 10 354 358.0 No_ligand No_ligand Inactive DFGin 6.7649 16.3749 BLAminus -136.9, -177.95 60.8, 80.27 -101.59, 22.61 284.86, 69.35 -60.66, -26.74 in-in in 9.6244 Saltbr-in 2.931 HRD-in -73.52, -46.58 69.84, -5.14 in-in-out SNCiio in-out ActLoopNT-in 2.9592 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -139.69, 148.7 APE9-dihe-na -65.85, -26.9 APE8-dihe-in -158.6, 145.11 APE8-rot-out 179.4 APE67-dihe-in -65.42, -14.51 -110.57, 9.67 APE12-dist-in 7.7359 APE11-dist-in 10.9274 APE10-dist-out 9.0371 APE9-dist-out 10.9379 T116C None None XRAY 1.9 0.231 0.263 A 364.0 345.0 0 31 31 0 [[23, 311]] 1.0 2gph Rattus norvegicus CMGC_MAPK1_RAT CMGC 2.4e-85 292.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4S30A P63086 4 355 358.0 No_ligand No_ligand Inactive DFGin 6.7914 16.1154 BLAminus -136.9, 174.46 69.38, 77.97 -92.54, 23.46 292.96, 87.93 -67.99, -29.24 out-out out 10.1214 Saltbr-out 5.7799 HRD-in -72.52, -51.08 71.1, -0.94 out-in-out SNCoio in-out ActLoopNT-in 2.7796 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.21, -33.1 APE9-dihe-na -68.08, 160.69 APE8-dihe-in -63.7, 128.99 APE8-rot-in 309.76 APE67-dihe-in -63.41, -20.91 -60.2, -45.12 APE12-dist-out 14.4479 APE11-dist-in 10.9999 APE10-dist-in 7.0966 APE9-dist-in 4.3861 I84A None None XRAY 2.0 0.197 0.249 A 358.0 342.0 1 31 31 0 [[23, 311]] 1.0 4s30 Rattus norvegicus CMGC_MAPK1_RAT CMGC 2.9e-85 292.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8RLXA P63086 4 355 358.0 No_ligand No_ligand Inactive DFGin 6.7939 16.264 BLAminus -136.33, 178.99 67.04, 77.21 -94.32, 26.09 290.49, 80.16 -56.85, -38.35 out-out out 10.1764 Saltbr-out 4.5312 HRD-in -75.47, -50.63 73.32, 2.39 out-in-none SNCoin in-none ActLoopNT-in 2.8342 ActLoopCT-none nonTYR APEdihe_aaini APEdist_iiii APE10-dihe-na -106.61, -38.11 APE9-dihe-na -63.83, 154.99 APE8-dihe-in -45.58, 118.98 APE8-rot-none 999.0 APE67-dihe-in -62.99, -15.78 -47.65, -52.52 APE12-dist-in 13.8742 APE11-dist-in 10.8475 APE10-dist-in 6.9337 APE9-dist-in 4.3195 T188A None None XRAY 1.6 0.212 0.241 A 365.0 347.0 0 31 31 0 [[23, 311]] 1.0 8rlx Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.1e-84 290.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8RMBA P63086 4 355 358.0 No_ligand No_ligand Inactive DFGin 6.6888 16.2958 BLAminus -131.88, -179.07 69.4, 78.54 -94.39, 26.44 287.26, 84.7 -64.41, -26.79 out-out out 10.0298 Saltbr-out 5.0583 HRD-in -69.65, -54.99 73.26, 0.79 out-in-in SNCoii in-in ActLoopNT-in 2.8075 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -96.84, -34.2 APE9-dihe-na -67.31, 156.97 APE8-dihe-in -52.37, 125.49 APE8-rot-na 195.38 APE67-dihe-in -73.42, -16.08 -51.38, -39.59 APE12-dist-in 13.9038 APE11-dist-in 10.7785 APE10-dist-in 7.1438 APE9-dist-in 4.576 R65S,T188D None None XRAY 1.55 0.2 0.23 A 365.0 347.0 0 31 31 0 [[23, 311]] 1.0 8rmb Rattus norvegicus CMGC_MAPK1_RAT CMGC 3.4e-84 288.6 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8RM2A P63086 4 355 358.0 No_ligand No_ligand Inactive DFGin 6.7044 16.2639 BLAminus -136.37, -179.19 65.67, 78.13 -97.92, 25.29 288.31, 76.42 -65.47, -27.78 in-out in 9.9641 Saltbr-out 4.5016 HRD-in -74.12, -52.33 76.93, -0.81 out-in-in SNCoii in-in ActLoopNT-in 2.7539 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -97.51, -40.55 APE9-dihe-na -66.04, 156.07 APE8-dihe-in -54.82, 132.13 APE8-rot-na 160.84 APE67-dihe-in -66.17, -16.18 -56.01, -48.51 APE12-dist-in 13.9982 APE11-dist-in 10.8253 APE10-dist-in 6.8694 APE9-dist-in 4.3776 T188E None None XRAY 1.55 0.202 0.236 A 365.0 347.0 0 31 31 0 [[23, 311]] 1.0 8rm2 Rattus norvegicus CMGC_MAPK1_RAT CMGC 3e-84 288.8 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XNEA P63086 9 354 358.0 TT4:401 Type1 Inactive DFGin 6.9062 16.5377 BLAminus -133.08, -178.31 62.87, 82.73 -101.62, 22.85 284.09, 79.92 -64.02, -26.26 out-out out 10.1683 Saltbr-out 6.631 HRD-in -73.52, -52.79 76.63, -2.65 out-in-out SNCoio in-out ActLoopNT-in 2.8538 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.86, -29.72 APE9-dihe-na -76.47, 164.24 APE8-dihe-in -60.32, 126.3 APE8-rot-in 310.6 APE67-dihe-in -64.56, -12.88 -50.2, -52.63 APE12-dist-out 14.3098 APE11-dist-in 11.1262 APE10-dist-in 7.0874 APE9-dist-in 4.4212 None None CME159,CME252 XRAY 1.8 0.18 0.218 A 346.0 346.0 0 31 31 0 [[23, 311]] 1.0 4xne Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.4 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XRJA P63086 9 354 358.0 620:401 Type1 Inactive DFGin 6.9642 17.0399 BLAminus -135.58, -179.99 62.78, 78.35 -99.18, 21.91 284.15, 79.36 -62.44, -24.71 out-out out 10.8346 Saltbr-out 6.8414 HRD-in -74.76, -52.56 80.19, -5.74 out-in-out SNCoio in-out ActLoopNT-in 2.8729 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -101.08, -24.1 APE9-dihe-na -79.03, 165.2 APE8-dihe-in -60.36, 127.57 APE8-rot-in 312.84 APE67-dihe-in -59.27, -14.85 -52.96, -57.21 APE12-dist-out 14.0217 APE11-dist-in 11.0423 APE10-dist-in 7.1108 APE9-dist-in 4.5185 None None CME159,CME252 XRAY 1.69 0.138 0.18 A 346.0 346.0 0 31 31 0 [[23, 311]] 1.0 4xrj Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.4 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XOYA P63086 9 353 358.0 DX4:401 Type1 Inactive DFGin 6.8384 16.4726 BLAminus -133.37, 174.39 67.24, 87.56 -100.05, 25.74 287.52, 74.09 -60.62, -29.03 out-out out 10.1548 Saltbr-out 6.1211 HRD-in -76.12, -52.95 76.38, -1.71 out-in-none SNCoin in-none ActLoopNT-in 2.7547 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 175.0 APE8-dihe-in -56.7, 130.92 APE8-rot-in 317.45 APE67-dihe-in -61.42, -22.5 -58.06, -51.04 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.6184 None None CME125,CME159,CME164,CME252 XRAY 2.1 0.182 0.218 A 351.0 330.0 8 31 28 3 [[23, 311]] 1.0 4xoy Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XP0A P63086 8 354 358.0 42A:404 Type1 Inactive DFGin 6.729 16.2799 BLAminus -130.85, 176.51 63.35, 87.23 -102.6, 23.78 288.28, 72.28 -57.91, -29.87 in-in in 9.8815 Saltbr-in 3.1124 HRD-in -74.37, -48.16 71.1, 5.03 in-in-out SNCiio in-out ActLoopNT-in 2.8019 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.65, -35.97 APE9-dihe-na -59.06, 154.53 APE8-dihe-in -49.14, 125.19 APE8-rot-in 314.16 APE67-dihe-in -59.44, -18.13 -55.5, -50.72 APE12-dist-out 14.5012 APE11-dist-in 11.2264 APE10-dist-in 7.3188 APE9-dist-in 4.2465 None None CME125,CME159,CME164,CME252 XRAY 1.46 0.192 0.214 A 351.0 340.0 0 31 31 0 [[23, 311]] 1.0 4xp0 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XP2A P63086 8 353 358.0 TT4:401 Type1 Inactive DFGin 6.6105 16.3478 BLAminus -133.41, 176.73 60.84, 85.42 -101.78, 22.05 288.36, 75.74 -60.65, -27.7 in-in in 9.7181 Saltbr-in 2.5334 HRD-in -72.91, -49.95 73.33, 0.56 in-in-out SNCiio in-out ActLoopNT-in 2.758 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -113.44, -29.8 APE9-dihe-na -58.45, 157.07 APE8-dihe-in -60.02, 123.7 APE8-rot-in 308.55 APE67-dihe-in -60.45, -18.84 -52.73, -49.68 APE12-dist-out 14.4688 APE11-dist-in 11.2247 APE10-dist-in 7.4964 APE9-dist-in 4.1831 None None CME159,CME252 XRAY 1.748 0.187 0.226 A 351.0 339.0 0 31 31 0 [[23, 311]] 1.0 4xp2 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XP3A P63086 8 354 358.0 DX4:401 Type1 Inactive DFGin 6.6537 16.0826 BLAminus -130.71, 174.0 60.88, 94.31 -106.94, 16.18 286.8, 78.81 -56.37, -28.23 in-out in 9.2564 Saltbr-out 5.2988 HRD-in -68.04, -51.13 71.44, 6.73 out-in-out SNCoio in-out ActLoopNT-in 2.821 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -121.82, 140.79 APE9-dihe-na 65.58, 179.47 APE8-dihe-in -91.24, 138.76 APE8-rot-in 296.06 APE67-dihe-in -60.07, -19.89 -42.76, -56.06 APE12-dist-in 13.6573 APE11-dist-in 11.2991 APE10-dist-out 9.0284 APE9-dist-in 3.1168 None None CME159,CME252 XRAY 1.782 0.15 0.179 A 351.0 341.0 0 31 31 0 [[23, 311]] 1.0 4xp3 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XRLA P63086 9 353 358.0 42A:402 Type1 Inactive DFGin 7.0316 16.4285 BLAminus -137.37, 172.94 64.21, 83.48 -101.2, 28.73 286.34, 64.33 -56.83, -41.4 out-in out 10.395 Saltbr-in 2.905 HRD-in -74.03, -50.49 73.87, 0.12 in-in-out SNCiio in-out ActLoopNT-in 2.8704 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na 75.98, -50.6 APE9-dihe-na -70.82, 161.2 APE8-dihe-in -60.45, 124.5 APE8-rot-in 303.76 APE67-dihe-in -59.6, -25.0 -51.49, -45.85 APE12-dist-out 14.4346 APE11-dist-in 11.7996 APE10-dist-in 7.3873 APE9-dist-in 4.1646 None None CME159 XRAY 2.554 0.162 0.229 A 345.0 338.0 0 31 31 0 [[23, 311]] 1.0 4xrl Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-84 290.0 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3C9WB P63086 6 354 358.0 HMY:1 Type1 Inactive DFGin 6.8713 15.7027 BLAminus -125.5, 170.88 61.8, 86.37 -105.46, 23.49 285.92, 70.36 -59.57, -35.08 in-out in 9.6739 Saltbr-out 5.1892 HRD-in -69.95, -57.99 88.54, -19.52 out-in-out SNCoio in-out ActLoopNT-in 2.739 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 93.1 APE8-rot-out 58.72 APE67-dihe-in -69.2, -21.0 -95.38, -7.01 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.197 0.274 B 357.0 336.0 13 31 18 13 [[23, 311]] 1.0 3c9w Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3ERKA P63086 6 355 358.0 SB4:800 Type1 Inactive DFGin 6.8828 16.5322 BLAminus -139.22, -175.27 62.55, 73.77 -98.77, 35.79 290.73, 71.27 -71.49, -19.85 out-out out 10.927 Saltbr-out 5.3764 HRD-in -66.65, -56.58 79.91, -6.17 out-in-out SNCoio in-out ActLoopNT-in 2.6518 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -104.75, -13.21 APE9-dihe-na -70.1, 154.45 APE8-dihe-in -51.93, 121.15 APE8-rot-in 313.05 APE67-dihe-in -54.85, -23.36 -42.38, -58.29 APE12-dist-out 14.2105 APE11-dist-in 10.8863 APE10-dist-in 7.3527 APE9-dist-in 4.4886 None None None XRAY 2.1 0.206 0.262 A 364.0 350.0 0 31 31 0 [[23, 311]] 1.0 3erk Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3QYWA P63086 9 354 358.0 6PB:359 Type1 Inactive DFGin 6.7724 16.2423 BLAminus -126.27, 171.8 63.41, 90.28 -101.23, 17.9 289.06, 76.0 -65.58, -21.25 in-out in 9.3847 Saltbr-out 5.4393 HRD-in -66.37, -52.17 74.75, 5.18 out-in-out SNCoio in-out ActLoopNT-in 2.8182 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -136.78, 141.02 APE9-dihe-na 67.83, 177.16 APE8-dihe-in -91.69, 140.04 APE8-rot-in 293.79 APE67-dihe-in -60.96, -17.88 -42.17, -57.45 APE12-dist-in 13.9314 APE11-dist-in 11.6311 APE10-dist-out 9.179 APE9-dist-in 3.2153 None None CME159 XRAY 1.5 0.16 0.188 A 364.0 341.0 0 31 31 0 [[23, 311]] 1.0 3qyw Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3QYZA P63086 8 354 358.0 Z8B:359 Type1 Inactive DFGin 6.7857 16.1243 BLAminus -131.85, 178.2 59.89, 83.49 -98.52, 20.59 286.71, 75.58 -65.79, -20.07 in-in in 9.3717 Saltbr-in 2.7067 HRD-in -71.88, -48.46 70.69, 5.97 in-in-out SNCiio in-out ActLoopNT-in 2.7745 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -117.88, 145.49 APE9-dihe-na 60.59, 179.24 APE8-dihe-in -89.94, 140.18 APE8-rot-in 293.88 APE67-dihe-in -62.03, -18.79 -42.88, -55.91 APE12-dist-in 13.5933 APE11-dist-in 11.3759 APE10-dist-out 8.9948 APE9-dist-in 3.1779 None None CME159 XRAY 1.46 0.175 0.195 A 364.0 341.0 0 31 31 0 [[23, 311]] 1.0 3qyz Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4ERKA P63086 6 355 358.0 OLO:800 Type1 Inactive DFGin 6.7904 16.323 BLAminus -144.14, 171.66 76.96, 71.97 -100.05, 31.86 291.48, 73.72 -66.9, -29.11 in-out in 9.9825 Saltbr-out 4.3497 HRD-in -62.75, -51.24 74.6, -9.96 out-in-out SNCoio in-out ActLoopNT-in 2.8248 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -92.93, -33.71 APE9-dihe-na -56.55, 147.82 APE8-dihe-in -47.77, 114.88 APE8-rot-in 305.72 APE67-dihe-in -41.49, -37.5 -39.09, -67.78 APE12-dist-out 14.5164 APE11-dist-in 11.0597 APE10-dist-in 7.2622 APE9-dist-in 4.4632 None None None XRAY 2.2 0.214 0.317 A 364.0 350.0 0 31 31 0 [[23, 311]] 1.0 4erk Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FI3A P63086 8 353 358.0 DJ2:405 Type1 Inactive DFGin 6.7482 16.2866 BLAminus -133.02, 179.12 56.62, 85.35 -98.75, 19.07 288.43, 77.21 -64.55, -20.4 in-in in 9.4531 Saltbr-in 2.5724 HRD-in -71.98, -48.68 74.21, 5.14 in-in-out SNCiio in-out ActLoopNT-in 2.7993 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -122.6, 149.83 APE9-dihe-na 60.97, 175.94 APE8-dihe-in -85.79, 141.34 APE8-rot-in 291.41 APE67-dihe-in -61.17, -18.63 -47.71, -53.47 APE12-dist-in 13.5524 APE11-dist-in 11.3859 APE10-dist-out 8.49 APE9-dist-in 3.1813 None None CME159 XRAY 1.52 0.152 0.198 A 364.0 339.0 0 31 31 0 [[23, 311]] 1.0 6fi3 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FI6A P63086 8 354 358.0 DF8:402 Type1 Inactive DFGin 6.7558 16.4271 BLAminus -129.61, 172.76 58.06, 90.55 -101.51, 21.9 287.13, 75.73 -61.55, -23.59 in-in in 9.6594 Saltbr-in 2.4682 HRD-in -74.02, -48.26 72.7, 5.76 in-in-out SNCiio in-out ActLoopNT-in 2.7965 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.07, -39.78 APE9-dihe-na -63.17, 166.3 APE8-dihe-in -68.67, 131.98 APE8-rot-in 309.05 APE67-dihe-in -64.9, -18.21 -59.38, -46.75 APE12-dist-out 14.5364 APE11-dist-in 11.3146 APE10-dist-in 7.2758 APE9-dist-in 4.2458 None None CME159,CME164 XRAY 1.65 0.154 0.196 A 364.0 339.0 0 31 31 0 [[23, 311]] 1.0 6fi6 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FJ0A P63086 9 353 358.0 A3N:406 Type1 Inactive DFGin 6.7195 16.1784 BLAminus -135.64, 179.75 55.58, 87.4 -101.72, 22.32 287.92, 73.95 -61.9, -25.39 in-in in 9.3021 Saltbr-in 2.6443 HRD-in -72.24, -49.4 71.7, 8.31 in-in-out SNCiio in-out ActLoopNT-in 2.7812 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -116.36, 140.79 APE9-dihe-na 65.93, 176.72 APE8-dihe-in -81.1, 141.24 APE8-rot-in 297.94 APE67-dihe-in -62.1, -17.49 -48.27, -52.66 APE12-dist-in 13.4585 APE11-dist-in 11.1445 APE10-dist-out 8.8238 APE9-dist-in 3.1308 None None CME159 XRAY 1.659 0.167 0.194 A 364.0 340.0 0 31 31 0 [[23, 311]] 1.0 6fj0 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FJBA P63086 8 354 358.0 AOC:402 Type1 Inactive DFGin 6.6924 16.4935 BLAminus -133.41, 178.52 59.61, 81.21 -96.96, 30.32 290.24, 65.76 -64.27, -25.03 in-in in 9.5103 Saltbr-in 2.6046 HRD-in -73.42, -48.69 73.94, -2.74 in-in-out SNCiio in-out ActLoopNT-in 2.7664 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.58, -43.1 APE9-dihe-na -61.66, 158.49 APE8-dihe-in -54.91, 131.22 APE8-rot-in 309.46 APE67-dihe-in -61.87, -16.83 -61.29, -49.41 APE12-dist-out 14.5284 APE11-dist-in 11.205 APE10-dist-in 7.3326 APE9-dist-in 4.4251 None None CME159 XRAY 1.85 0.185 0.226 A 364.0 338.0 0 31 31 0 [[23, 311]] 1.0 6fjb Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FLEA P63086 8 353 358.0 DQ2:402 Type1 Inactive DFGin 6.7554 16.3123 BLAminus -132.42, -179.89 61.12, 80.88 -95.96, 21.93 283.86, 75.2 -68.37, -17.45 in-out in 9.8721 Saltbr-out 4.5677 HRD-in -72.01, -49.08 74.41, 3.13 out-in-out SNCoio in-out ActLoopNT-in 2.7779 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -103.79, -39.57 APE9-dihe-na -62.1, 158.77 APE8-dihe-in -56.99, 128.88 APE8-rot-in 310.95 APE67-dihe-in -63.61, -16.07 -56.12, -51.68 APE12-dist-out 14.5267 APE11-dist-in 11.2518 APE10-dist-in 7.2747 APE9-dist-in 4.2562 None None CME159 XRAY 1.48 0.156 0.194 A 364.0 341.0 0 31 31 0 [[23, 311]] 1.0 6fle Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FLVA P63086 9 354 358.0 DTW:403 Type1 Inactive DFGin 6.8201 16.0817 BLAminus -129.61, 176.45 61.68, 86.4 -102.86, 19.47 290.44, 74.88 -65.53, -18.99 in-in in 9.6931 Saltbr-in 2.8744 HRD-in -65.72, -51.77 75.22, 7.67 in-in-out SNCiio in-out ActLoopNT-in 2.7693 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -127.84, 139.67 APE9-dihe-na 67.16, 178.45 APE8-dihe-in -90.65, 145.23 APE8-rot-in 298.33 APE67-dihe-in -64.07, -18.24 -51.2, -52.88 APE12-dist-in 13.5857 APE11-dist-in 11.5693 APE10-dist-out 8.9673 APE9-dist-in 3.1704 None None CME159 XRAY 1.91 0.193 0.219 A 364.0 345.0 0 31 31 0 [[23, 311]] 1.0 6flv Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FMAA P63086 9 354 358.0 DU8:406 Type1 Inactive DFGin 6.7238 16.151 BLAminus -132.1, 177.54 58.89, 88.96 -101.02, 19.64 286.47, 76.34 -64.51, -22.62 in-in in 9.5167 Saltbr-in 2.8449 HRD-in -73.29, -48.11 70.04, 8.22 in-in-out SNCiio in-out ActLoopNT-in 2.7813 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -114.17, 142.41 APE9-dihe-na 60.94, -176.67 APE8-dihe-in -96.38, 137.03 APE8-rot-in 292.6 APE67-dihe-in -63.9, -17.51 -43.25, -50.72 APE12-dist-in 13.4629 APE11-dist-in 11.0446 APE10-dist-out 8.9074 APE9-dist-in 3.1083 None None CME159 XRAY 1.667 0.145 0.186 A 364.0 341.0 0 31 31 0 [[23, 311]] 1.0 6fma Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FN5A P63086 9 354 358.0 DVZ:401 Type1 Inactive DFGin 6.666 16.1829 BLAminus -133.39, -179.42 58.41, 90.82 -107.26, 25.27 285.06, 71.41 -66.7, -23.69 out-in out 10.1183 Saltbr-in 2.3051 HRD-in -70.03, -53.72 74.31, 2.57 in-in-out SNCiio in-out ActLoopNT-in 2.8771 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -114.46, -41.07 APE9-dihe-na -60.45, 164.43 APE8-dihe-in -64.82, 127.21 APE8-rot-in 303.54 APE67-dihe-in -60.71, -17.61 -58.58, -49.17 APE12-dist-out 14.5752 APE11-dist-in 11.326 APE10-dist-in 7.3582 APE9-dist-in 4.3175 None None CME159 XRAY 1.932 0.209 0.241 A 364.0 336.0 2 31 31 0 [[23, 311]] 1.0 6fn5 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FQ7A P63086 9 354 358.0 E2K:403 Type1 Inactive DFGin 6.7343 16.2785 BLAminus -130.32, 175.59 58.0, 91.1 -100.86, 17.55 289.19, 77.23 -64.87, -20.52 in-out in 9.5602 Saltbr-out 4.2788 HRD-in -69.51, -49.87 69.84, 9.15 out-in-out SNCoio in-out ActLoopNT-in 2.8212 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -125.72, 147.96 APE9-dihe-na 61.2, 155.67 APE8-dihe-in -48.79, 131.74 APE8-rot-in 305.11 APE67-dihe-in -62.45, -19.67 -49.62, -53.07 APE12-dist-in 13.684 APE11-dist-in 11.5437 APE10-dist-out 8.5248 APE9-dist-in 3.3163 None None CME159 XRAY 1.6 0.139 0.18 A 364.0 342.0 0 31 31 0 [[23, 311]] 1.0 6fq7 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FR1A P63086 9 354 358.0 E3K:408 Type1 Inactive DFGin 6.7164 16.5026 BLAminus -132.59, 178.04 61.94, 83.51 -99.58, 19.2 286.68, 75.23 -65.16, -18.28 in-out in 9.6485 Saltbr-out 4.06 HRD-in -71.67, -49.57 72.07, 6.53 out-in-out SNCoio in-out ActLoopNT-in 2.7833 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -118.52, 141.33 APE9-dihe-na 65.72, 174.93 APE8-dihe-in -83.88, 143.1 APE8-rot-in 296.31 APE67-dihe-in -63.95, -18.29 -49.1, -51.62 APE12-dist-in 13.5041 APE11-dist-in 11.3391 APE10-dist-out 8.8365 APE9-dist-in 3.1101 None None CME159 XRAY 1.561 0.154 0.199 A 364.0 342.0 0 31 31 0 [[23, 311]] 1.0 6fr1 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FRPA P63086 9 354 358.0 ZAS:407 Type1 Inactive DFGin 6.6647 16.0618 BLAminus -136.36, -179.11 56.41, 86.75 -99.02, 23.85 287.92, 74.74 -61.43, -28.68 in-out in 9.4539 Saltbr-out 4.1408 HRD-in -73.66, -48.98 71.95, 4.21 out-in-out SNCoio in-out ActLoopNT-in 2.7413 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.19, -44.31 APE9-dihe-na -59.59, 164.61 APE8-dihe-in -68.46, 131.84 APE8-rot-in 309.99 APE67-dihe-in -61.95, -18.9 -59.83, -47.47 APE12-dist-out 14.6096 APE11-dist-in 11.2024 APE10-dist-in 7.0802 APE9-dist-in 4.2147 None None CME159 XRAY 1.53 0.164 0.21 A 364.0 340.0 0 31 31 0 [[23, 311]] 1.0 6frp Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FXVA P63086 9 354 358.0 E9W:405 Type1 Inactive DFGin 6.6082 16.6196 BLAminus -133.38, -178.96 57.91, 79.65 -95.09, 25.27 288.04, 71.12 -68.75, -20.09 in-out in 9.8833 Saltbr-out 5.1943 HRD-in -72.43, -47.45 73.54, 4.99 out-in-out SNCoio in-out ActLoopNT-in 2.8056 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -102.75, -41.46 APE9-dihe-na -59.75, 157.53 APE8-dihe-in -51.19, 131.87 APE8-rot-in 312.28 APE67-dihe-in -63.95, -12.15 -64.35, -47.16 APE12-dist-out 14.5614 APE11-dist-in 11.1828 APE10-dist-in 7.3299 APE9-dist-in 4.3142 None None CME159,CME252 XRAY 1.53 0.154 0.193 A 364.0 337.0 1 31 31 0 [[23, 311]] 1.0 6fxv Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR2A P63086 9 354 358.0 WNT:403 Type1 Inactive DFGin 7.1206 15.8412 BLAminus -112.87, 156.99 74.31, 96.4 -102.5, 22.69 283.17, 79.7 -72.9, -13.1 in-in in 9.8905 Saltbr-in 2.7797 HRD-in -74.13, -48.82 72.48, 6.28 in-in-out SNCiio in-out ActLoopNT-in 2.8141 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -100.08, -38.56 APE9-dihe-na -64.61, 164.24 APE8-dihe-in -61.33, 129.63 APE8-rot-in 313.39 APE67-dihe-in -65.77, -17.85 -61.14, -43.62 APE12-dist-out 14.7255 APE11-dist-in 11.397 APE10-dist-in 7.3403 APE9-dist-in 4.2516 None None CME159,CME252 XRAY 1.64 0.131 0.178 A 364.0 340.0 0 31 31 0 [[23, 311]] 1.0 8qr2 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR3A P63086 9 354 358.0 WNC:405 Type1 Inactive DFGin 7.2392 15.767 BLAminus -111.72, 158.63 66.9, 99.39 -105.45, 22.8 279.88, 80.76 -71.45, -20.97 in-in in 9.7836 Saltbr-in 2.9179 HRD-in -71.41, -51.22 75.55, 6.15 in-in-out SNCiio in-out ActLoopNT-in 2.7533 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -51.43, 150.97 APE9-dihe-na 60.18, 174.67 APE8-dihe-in -78.46, 135.82 APE8-rot-in 299.74 APE67-dihe-in -63.79, -18.52 -48.38, -52.85 APE12-dist-in 13.6335 APE11-dist-in 11.6857 APE10-dist-out 8.7477 APE9-dist-in 3.257 None None CME159,CME252 XRAY 1.65 0.145 0.189 A 364.0 346.0 0 31 31 0 [[23, 311]] 1.0 8qr3 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR4A P63086 9 354 358.0 WN8:403 Type1 Inactive DFGin 7.026 15.787 BLAminus -120.79, 162.9 63.51, 96.43 -106.96, 24.9 284.25, 77.14 -73.26, -20.35 in-in in 9.7539 Saltbr-in 2.7507 HRD-in -72.28, -52.65 72.34, 11.91 in-in-out SNCiio in-out ActLoopNT-in 2.7665 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -110.9, -34.47 APE9-dihe-na -68.4, 171.33 APE8-dihe-in -73.8, 132.91 APE8-rot-in 307.77 APE67-dihe-in -60.68, -16.14 -53.19, -56.89 APE12-dist-out 14.3632 APE11-dist-in 11.3081 APE10-dist-in 6.9082 APE9-dist-in 4.0824 None None CME159,CME252 XRAY 1.92 0.191 0.224 A 364.0 340.0 0 31 31 0 [[23, 311]] 1.0 8qr4 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR5A P63086 9 354 358.0 WMC:402 Type1 Inactive DFGin 7.0636 15.8269 BLAminus -112.33, 161.57 72.1, 92.3 -101.75, 27.09 284.62, 76.44 -72.23, -18.18 in-in in 9.9107 Saltbr-in 2.8918 HRD-in -73.83, -48.38 72.35, 3.86 in-in-out SNCiio in-out ActLoopNT-in 2.8141 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -102.57, -41.82 APE9-dihe-na -59.41, 159.7 APE8-dihe-in -55.08, 130.0 APE8-rot-in 313.78 APE67-dihe-in -64.89, -17.55 -56.57, -50.38 APE12-dist-out 14.6747 APE11-dist-in 11.3403 APE10-dist-in 7.3274 APE9-dist-in 4.2951 None None CME159,CME252 XRAY 1.6 0.141 0.188 A 364.0 342.0 0 31 31 0 [[23, 311]] 1.0 8qr5 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR6A P63086 9 354 358.0 WMN:406 Type1 Inactive DFGin 7.2128 16.0863 BLAminus -107.94, 154.41 70.42, 98.93 -106.03, 21.97 285.57, 80.57 -73.35, -18.04 out-in out 10.1118 Saltbr-in 2.6054 HRD-in -68.81, -51.2 72.85, 10.04 in-in-out SNCiio in-out ActLoopNT-in 2.7565 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -57.77, 146.92 APE9-dihe-na 67.75, -177.29 APE8-dihe-in -93.0, 139.82 APE8-rot-in 292.68 APE67-dihe-in -65.03, -17.98 -44.28, -53.83 APE12-dist-in 13.727 APE11-dist-in 11.6411 APE10-dist-out 8.9298 APE9-dist-in 3.2248 None None CME159,CME252 XRAY 1.65 0.155 0.199 A 364.0 346.0 0 31 31 0 [[23, 311]] 1.0 8qr6 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR7A P63086 9 357 358.0 WMI:405 Type1 Inactive DFGin 7.2446 15.7889 BLAminus -110.79, 160.7 66.46, 96.98 -104.77, 21.8 281.2, 80.4 -70.56, -19.87 in-in in 9.6724 Saltbr-in 2.8218 HRD-in -68.99, -49.95 71.83, 9.23 in-in-out SNCiio in-out ActLoopNT-in 2.8033 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -59.24, 151.05 APE9-dihe-na 62.57, 171.67 APE8-dihe-in -76.36, 134.64 APE8-rot-in 299.59 APE67-dihe-in -62.19, -19.6 -46.84, -55.69 APE12-dist-in 13.6365 APE11-dist-in 11.8605 APE10-dist-out 8.7016 APE9-dist-in 3.2713 None None CME159,CME252 XRAY 1.51 0.146 0.188 A 364.0 341.0 0 31 31 0 [[23, 311]] 1.0 8qr7 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR8A P63086 9 354 358.0 WN2:403 Type1 Inactive DFGin 7.1171 15.9549 BLAminus -106.94, 156.78 69.13, 99.72 -106.38, 24.87 286.33, 74.19 -68.77, -23.2 in-in in 9.8827 Saltbr-in 2.7663 HRD-in -71.77, -48.28 72.09, 6.42 in-in-out SNCiio in-out ActLoopNT-in 2.8302 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -89.24, 148.72 APE9-dihe-na 57.88, 155.99 APE8-dihe-in -47.44, 134.77 APE8-rot-in 307.51 APE67-dihe-in -60.43, -20.6 -50.3, -54.04 APE12-dist-in 13.3421 APE11-dist-in 11.4517 APE10-dist-out 8.6647 APE9-dist-in 3.3596 None None CME159,CME252 XRAY 1.61 0.158 0.2 A 364.0 342.0 0 31 31 0 [[23, 311]] 1.0 8qr8 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QR9A P63086 9 354 358.0 WMX:407 Type1 Inactive DFGin 7.0376 16.0252 BLAminus -106.8, 150.63 74.72, 94.19 -98.08, 19.98 287.02, 79.69 -69.89, -19.87 out-in out 10.0191 Saltbr-in 3.2979 HRD-in -70.08, -52.13 75.82, 4.35 in-in-out SNCiio in-out ActLoopNT-in 2.7525 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -54.65, 151.23 APE9-dihe-na 56.4, 163.59 APE8-dihe-in -68.57, 140.2 APE8-rot-in 303.05 APE67-dihe-in -65.92, -15.94 -54.49, -52.24 APE12-dist-in 13.6041 APE11-dist-in 11.839 APE10-dist-out 8.7682 APE9-dist-in 3.2698 None None CME159,CME252 XRAY 1.94 0.18 0.222 A 364.0 346.0 0 31 31 0 [[23, 311]] 1.0 8qr9 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QRAA P63086 9 354 358.0 WM6:403 Type1 Inactive DFGin 6.9075 15.7961 BLAminus -118.02, 161.64 67.93, 95.61 -103.21, 22.49 286.51, 76.31 -69.0, -16.04 in-in in 9.7183 Saltbr-in 2.5782 HRD-in -72.56, -50.99 74.14, 4.54 in-in-out SNCiio in-out ActLoopNT-in 2.8003 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -55.96, 149.23 APE9-dihe-na 59.49, 149.86 APE8-dihe-in -31.13, 131.38 APE8-rot-in 308.8 APE67-dihe-in -64.8, -18.22 -54.49, -50.75 APE12-dist-in 13.3775 APE11-dist-in 11.5657 APE10-dist-out 8.7214 APE9-dist-in 3.3207 None None CME159,CME252 XRAY 1.55 0.144 0.182 A 364.0 341.0 0 31 31 0 [[23, 311]] 1.0 8qra Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QRBA P63086 9 356 358.0 WLZ:406 Type1 Inactive DFGin 7.1106 15.7814 BLAminus -127.57, 160.33 62.59, 99.91 -109.15, 27.72 282.94, 75.75 -73.21, -20.66 in-in in 9.9553 Saltbr-in 2.9813 HRD-in -72.73, -50.72 71.82, 13.14 in-in-out SNCiio in-out ActLoopNT-in 2.7851 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -49.82, 143.23 APE9-dihe-na 61.86, 160.49 APE8-dihe-in -54.61, 134.6 APE8-rot-in 304.07 APE67-dihe-in -61.8, -17.63 -47.98, -58.12 APE12-dist-in 13.5948 APE11-dist-in 11.5615 APE10-dist-out 8.7602 APE9-dist-in 3.4345 None None CME159 XRAY 1.51 0.178 0.209 A 364.0 348.0 0 31 31 0 [[23, 311]] 1.0 8qrb Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 8QRCA P63086 9 354 358.0 WMT:402 Type1 Inactive DFGin 6.7805 15.7581 BLAminus -123.41, 169.3 60.02, 91.76 -97.8, 33.64 285.09, 75.77 -62.73, -31.26 out-in out 10.1144 Saltbr-in 2.9344 HRD-in -73.97, -50.48 72.02, 10.48 in-in-out SNCiio in-out ActLoopNT-in 2.7474 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.01, -37.31 APE9-dihe-na -64.72, 166.95 APE8-dihe-in -66.38, 136.7 APE8-rot-in 311.84 APE67-dihe-in -61.95, -18.28 -62.38, -48.62 APE12-dist-out 14.3716 APE11-dist-in 11.1549 APE10-dist-in 6.9714 APE9-dist-in 4.2394 None None CME159,CME252 XRAY 1.69 0.151 0.198 A 364.0 337.0 0 31 31 0 [[23, 311]] 1.0 8qrc Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 2Z7LA P63086 16 355 358.0 S91:61001 Type1 Inactive DFGin 6.8008 16.4338 BLAminus -136.9, 170.79 66.29, 86.62 -103.07, 34.52 288.59, 65.29 -58.02, -43.27 out-out out 10.2385 Saltbr-out 4.5892 HRD-in -77.28, -55.92 74.77, 0.96 out-in-in SNCoii in-in ActLoopNT-in 2.7255 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -88.62, -49.81 APE9-dihe-na -40.28, 150.05 APE8-dihe-in -49.12, 125.58 APE8-rot-in 308.41 APE67-dihe-in -53.59, -24.0 -51.3, -52.67 APE12-dist-in 13.9992 APE11-dist-in 10.9277 APE10-dist-in 6.843 APE9-dist-in 4.1581 None None None XRAY 2.41 0.223 0.276 A 366.0 329.0 3 31 31 0 [[23, 311]] 1.0 2z7l Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 5KE0A P63086 16 355 358.0 6S9:401 Type1 Inactive DFGin 6.8311 15.0978 BLAminus -129.16, 176.97 69.35, 80.56 -97.81, 23.27 286.18, 69.95 -66.05, -22.44 in-in in 9.3068 Saltbr-in 2.7534 HRD-in -76.1, -51.61 73.82, 5.91 in-in-out SNCiio in-out ActLoopNT-in 2.7961 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -84.54, -37.3 APE9-dihe-na -71.22, 162.96 APE8-dihe-in -52.88, 123.68 APE8-rot-in 310.69 APE67-dihe-in -61.3, -20.37 -50.36, -53.16 APE12-dist-out 14.4313 APE11-dist-in 11.1643 APE10-dist-in 6.8597 APE9-dist-in 4.3913 None None None XRAY 1.68 0.169 0.191 A 366.0 340.0 0 31 31 0 [[23, 311]] 1.0 5ke0 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 5U6IA P63086 16 355 358.0 81Y:401 Type1 Inactive DFGin 6.8248 14.8408 BLAminus -131.29, 174.92 68.74, 80.64 -97.46, 21.9 283.5, 71.75 -59.58, -27.64 in-in in 9.2022 Saltbr-in 2.7642 HRD-in -76.03, -52.9 75.2, 3.34 in-in-out SNCiio in-out ActLoopNT-in 2.8153 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -88.65, -39.48 APE9-dihe-na -69.18, 161.4 APE8-dihe-in -50.56, 122.76 APE8-rot-in 310.75 APE67-dihe-in -61.33, -21.23 -51.09, -50.17 APE12-dist-out 14.4865 APE11-dist-in 11.167 APE10-dist-in 6.9764 APE9-dist-in 4.4139 None None None XRAY 1.69 0.169 0.186 A 366.0 339.0 1 31 31 0 [[23, 311]] 1.0 5u6i Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 5HD7A P63086 9 355 358.0 38Z:401 Type1 Inactive DFGin 6.6169 16.3974 BLAminus -128.09, 178.37 68.56, 85.26 -107.06, 21.62 285.69, 78.69 -70.28, -12.54 in-in in 9.5452 Saltbr-in 2.6662 HRD-in -71.35, -50.28 70.7, 8.65 in-in-out SNCiio in-out ActLoopNT-in 2.7976 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.73, -37.18 APE9-dihe-na -62.95, 158.16 APE8-dihe-in -50.32, 124.93 APE8-rot-in 314.5 APE67-dihe-in -63.38, -19.4 -51.82, -51.63 APE12-dist-out 14.404 APE11-dist-in 11.122 APE10-dist-in 7.2822 APE9-dist-in 4.4034 G167D None None XRAY 1.69 0.182 0.207 A 365.0 347.0 0 31 31 0 [[23, 311]] 1.0 5hd7 Rattus norvegicus CMGC_MAPK1_RAT CMGC 8e-84 287.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4N4SA P63086 8 356 358.0 2H1:401 Type1.5_Back Inactive DFGin 6.8159 16.7081 BLAminus -116.12, 166.7 66.69, 89.49 -99.58, 27.86 294.96, 80.31 -63.14, -30.1 out-out out 10.4441 Saltbr-out 7.6209 HRD-in -75.34, -53.11 71.98, 8.82 out-in-out SNCoio in-out ActLoopNT-in 2.8038 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -140.29, 155.03 APE9-dihe-na -61.58, -38.32 APE8-dihe-in -149.07, 139.77 APE8-rot-out 171.6 APE67-dihe-in -66.78, -20.12 -102.79, 12.94 APE12-dist-in 9.0893 APE11-dist-in 12.189 APE10-dist-out 8.994 APE9-dist-out 10.9723 Q103A,C164L None None XRAY 2.2 0.223 0.253 A 359.0 342.0 7 31 24 7 [[23, 311]] 1.0 4n4s Rattus norvegicus CMGC_MAPK1_RAT CMGC 5e-85 291.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4N4SB P63086 8 356 358.0 2H1:401 Type1.5_Back Inactive DFGin 6.722 16.8898 BLAminus -117.75, 167.45 66.96, 88.97 -98.01, 25.84 293.93, 90.09 -63.54, -29.88 out-out out 10.5039 Saltbr-out 7.8397 HRD-in -75.26, -52.69 71.86, 7.64 out-in-out SNCoio in-out ActLoopNT-in 2.8064 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 179.95 APE8-dihe-in -141.22, 138.76 APE8-rot-out 169.5 APE67-dihe-in -67.64, -21.96 -101.08, 11.3 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.3672 Q103A,C164L None None XRAY 2.2 0.223 0.253 B 359.0 337.0 12 31 19 12 [[23, 311]] 1.0 4n4s Rattus norvegicus CMGC_MAPK1_RAT CMGC 5e-85 291.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4XOZA P63086 8 354 358.0 620:401 Type1.5_Front Inactive DFGin 7.0338 17.1796 BLAminus -134.11, -179.17 64.03, 75.89 -98.44, 22.92 284.72, 79.08 -64.36, -27.3 out-out out 10.9544 Saltbr-out 7.0581 HRD-in -69.47, -52.23 72.29, -1.02 out-in-out SNCoio in-out ActLoopNT-in 2.8283 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -105.18, -18.66 APE9-dihe-na -75.46, 166.86 APE8-dihe-in -66.79, 127.73 APE8-rot-in 308.37 APE67-dihe-in -59.61, -18.58 -53.08, -50.65 APE12-dist-out 14.394 APE11-dist-in 11.0734 APE10-dist-in 7.3638 APE9-dist-in 4.4737 None None CME159 XRAY 1.95 0.147 0.188 A 351.0 342.0 0 31 31 0 [[23, 311]] 1.0 4xoz Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4QYYA P63086 13 353 358.0 3G7:401 Type1.5_Front Inactive DFGin 6.7251 16.3904 BLAminus -132.71, 173.31 70.0, 86.57 -103.46, 23.97 286.71, 76.13 -60.77, -27.68 in-in in 9.5365 Saltbr-in 2.6005 HRD-in -74.52, -50.72 73.19, 8.77 in-in-out SNCiio in-out ActLoopNT-in 2.7846 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.27, -36.79 APE9-dihe-na -64.89, 158.32 APE8-dihe-in -46.41, 120.56 APE8-rot-in 314.36 APE67-dihe-in -60.78, -19.5 -50.53, -52.6 APE12-dist-out 14.3811 APE11-dist-in 11.1066 APE10-dist-in 7.3001 APE9-dist-in 4.4257 None None None XRAY 1.65 0.229 0.259 A 365.0 337.0 0 31 31 0 [[23, 311]] 1.0 4qyy Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 5HD4A P63086 9 355 358.0 38Z:401 Type1.5_Front Inactive DFGin 6.7617 16.3963 BLAminus -132.15, 171.71 72.04, 89.95 -105.49, 25.28 288.89, 74.15 -62.94, -29.6 in-in in 9.6091 Saltbr-in 2.6511 HRD-in -73.9, -52.49 73.6, 6.76 in-in-out SNCiio in-out ActLoopNT-in 2.7885 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -96.81, -40.96 APE9-dihe-na -60.91, 155.22 APE8-dihe-in -46.4, 120.98 APE8-rot-in 315.89 APE67-dihe-in -62.79, -18.63 -49.8, -50.9 APE12-dist-out 14.32 APE11-dist-in 11.0677 APE10-dist-in 7.1595 APE9-dist-in 4.4363 None None None XRAY 1.45 0.177 0.199 A 365.0 347.0 0 31 31 0 [[23, 311]] 1.0 5hd4 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6CPWA P63086 16 355 358.0 F8V:403 Type1.5_Front Inactive DFGin 6.7287 16.4334 BLAminus -131.65, 172.57 66.32, 87.15 -102.19, 23.21 287.0, 74.02 -60.73, -27.83 in-in in 9.7402 Saltbr-in 2.6096 HRD-in -72.55, -51.86 72.75, 5.47 in-in-out SNCiio in-out ActLoopNT-in 2.82 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -95.83, -38.85 APE9-dihe-na -58.06, 150.18 APE8-dihe-in -41.46, 122.36 APE8-rot-in 313.47 APE67-dihe-in -62.43, -17.55 -55.27, -49.2 APE12-dist-out 14.4183 APE11-dist-in 11.1119 APE10-dist-in 7.425 APE9-dist-in 4.4034 None None None XRAY 1.85 0.19 0.224 A 366.0 328.0 5 31 31 0 [[23, 311]] 1.0 6cpw Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6DCGA P63086 16 354 358.0 G67:403 Type1.5_Front Inactive DFGin 6.7381 16.3113 BLAminus -128.96, 170.91 70.91, 87.53 -102.77, 23.72 285.91, 75.71 -65.7, -26.65 in-in in 9.5778 Saltbr-in 2.5866 HRD-in -74.26, -51.41 73.54, 7.44 in-in-out SNCiio in-out ActLoopNT-in 2.8149 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -98.1, -35.07 APE9-dihe-na -65.64, 158.57 APE8-dihe-in -47.89, 121.75 APE8-rot-in 313.14 APE67-dihe-in -64.08, -17.48 -49.3, -51.53 APE12-dist-out 14.4524 APE11-dist-in 11.1167 APE10-dist-in 7.306 APE9-dist-in 4.3726 None None None XRAY 1.45 0.178 0.199 A 366.0 326.0 5 31 31 0 [[23, 311]] 1.0 6dcg Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6FJZA P63086 9 354 358.0 DKW:402 Type1 Inactive DFGin 6.6634 16.4202 None -134.8, -179.27 82.46, -86.27 66.98, 18.08 291.18, 83.08 -68.21, -20.47 in-in in 9.2842 Saltbr-in 2.7213 HRD-in -71.29, -49.89 75.9, -0.67 in-in-out SNCiio in-out ActLoopNT-in 2.7431 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -99.27, -45.48 APE9-dihe-na -54.12, 158.83 APE8-dihe-in -55.9, 129.11 APE8-rot-in 307.1 APE67-dihe-in -60.37, -17.39 -59.77, -49.92 APE12-dist-out 14.2719 APE11-dist-in 11.2255 APE10-dist-in 7.301 APE9-dist-in 4.4081 None None CME159 XRAY 1.864 0.174 0.207 A 364.0 346.0 0 31 31 0 [[23, 311]] 1.0 6fjz Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.4e-85 293.1 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 4I5HA P63086 9 356 358.0 G17:401 Type2 Inactive DFGout 16.7361 7.9906 None -129.89, 156.41 -129.44, 98.8 -58.76, -39.89 187.16, 88.85 121.71, -175.9 in-in in 8.6475 Saltbr-in 2.6758 HRD-in -71.0, -49.44 78.62, -12.56 in-out-out SNCioo out-out ActLoopNT-out 18.2558 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -68.91, 157.99 APE9-dihe-na -71.89, 135.07 APE8-dihe-in -136.31, 148.41 APE8-rot-out 167.99 APE67-dihe-in -62.3, -21.48 -106.14, 1.26 APE12-dist-in 13.4361 APE11-dist-in 8.7287 APE10-dist-out 10.207 APE9-dist-out 9.9537 Q103A,C164L None None XRAY 1.9 0.22 0.257 A 359.0 335.0 7 31 24 7 [[23, 311]] 1.0 4i5h Rattus norvegicus CMGC_MAPK1_RAT CMGC 5e-85 291.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 6RFOA P63086 12 355 358.0 No_ligand No_ligand Inactive None 999.0 999.0 None 999.0, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 in-out in 9.7959 Saltbr-out 8.4645 HRD-in -69.04, -52.69 71.19, -0.59 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 1.7 0.16 0.219 A 372.0 292.0 15 25 19 6 [[23, 311]] 1.0 6rfo Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.1e-85 293.4 1.0 301.0 301.0 167 168 169 171 173 52 69 73 144 146 145 147.0 208 192 187 186 185 184 183 182 181 104 Mitogen-activated protein kinase 1
MAPK1 MK01_RAT 3C9WA P63086 6 354 358.0 HMY:1 Type1 None DFGin 6.9994 15.702 BLAminus -123.81, 173.38 50.82, 89.77 -103.35, 17.03 287.88, 69.21 -57.05, -26.18 in-in in 9.643 Saltbr-in 2.6942 HRD-in -68.6, -50.76 75.06, -2.41 in-in-none SNCiin in-none ActLoopNT-in 2.7402 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 147.03 APE8-rot-in 303.8 APE67-dihe-in -65.62, -21.36 -55.58, -26.02 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.5 0.197 0.274 A 357.0 336.0 13 31 18 13 [[23, 311]] 1.0 3c9w Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.3e-85 293.2 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1