8C3Q

DYRK1A (Dual specificity tyrosine-phosphorylation-regulated kinase 1A)
Group: CMGC
Uniprot: DYR1A_HUMAN
Organism: Homo sapiens
Domain boundary: 159 - 479
Resolu: 2.32

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in RUT Type1.5_Back 134 - 480 0
B Active DFGin BLAminus in-in in-in RUT Type1.5_Back 136 - 480 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       135        145        155        165 
dsshkkerkv YNDGYDDDNY DYIVKNGEKW MDRYEIDSLI 
       175        185        195        205 
GKGSFGQVVK AYDRVEQEWV AIKIIKNKKA FLNQAQIEVR 
       215        225        235        245 
LLELMNKHDt EMKYYIVHLK RHFMFRNHLC LVFEMLSYNL 
       255        265        275        285 
YDLLRNTNFR GVSLNLTRKF AQQMCTALLF LATPELSIIH 
       295        305        315        325 
CDLKPENILL CNPKRSAIKI VDFGSSCQLG QRIYQYIQSR 
       335        345        355        365 
FYRSPEVLLG MPYDLAIDMW SLGCILVEMH TGEPLFSGAN 
       375        385        395        405 
EVDQMNKIVE VLGIPPAHIL DQAPKARKFF EKLPDGTWNL 
       415        425        435        445 
KKTKDGKREY KPPGTRKLHN ILGVETGGPG GRRAGESGHT 
       455        465        475        485 
VADYLKFKDL ILRMLDYDPK TRIQPYYALQ HSFFKktade 
         - 
gtnthhhhhh
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X321