KinCore

Ligand: QY8

Total number of chains: 2

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLAminus	2	7A4RA

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein
CMGC	DYRK1A	DYR1A_HUMAN	7A4R	1.8	Active	DFGin‑BLAminus	in-in	in-in	QY8	Type1	148 - 479	0	X321	None	Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC	DYRK1A	DYR1A_HUMAN	7A4R	1.8	Active	DFGin‑BLAminus	in-in	in-in	QY8	Type1	148 - 479	0	X321	None	Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: QY8

Total number of chains: 2

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLAminus	2	7A4RA

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism
CMGC	DYRK1A	DYR1A_HUMAN	7A4R	1.8	Active	DFGin‑BLAminus	in-in	in-in	QY8	Type1	148 - 479	0	X321	None	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens
CMGC	DYRK1A	DYR1A_HUMAN	7A4R	1.8	Active	DFGin‑BLAminus	in-in	in-in	QY8	Type1	148 - 479	0	X321	None	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens

Ligand: QY8

Total number of chains: 0

Spatial label	Dihedral label	Number of Chains	Representative

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism