Ligand: CUE

Total number of chains: 3
Active chains: 3
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 6HNWA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CSNK2A1 CSK21_HUMAN 6HNWA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CUE Type1 3 - 330 0 None None Casein kinase II subunit alpha
CMGC DYRK1A DYR1A_HUMAN 8YEVA 2.252 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CUE Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 8YEVB 2.252 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CUE Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: CUE

Total number of chains: 3
Active chains: 3
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 6HNWA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CSNK2A1 CSK21_HUMAN 6HNWA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CUE Type1 3 - 330 0 None None Casein kinase II subunit alpha Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 8YEVA 2.252 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CUE Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 8YEVB 2.252 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii CUE Type1 135 - 480 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens

Ligand: CUE

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism