KinCore

Ligand: QZ2

Total number of chains: 2

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLAminus	2	7A55A

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein
CMGC	DYRK1A	DYR1A_HUMAN	7A55	2.2	Active	DFGin‑BLAminus	in-in	in-in	QZ2	Type1	136 - 481	0	X321	None	Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC	DYRK1A	DYR1A_HUMAN	7A55	2.2	Inactive	DFGin‑BLAminus	in-in	in-out	QZ2	Type1	134 - 481	0	X321	None	Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: QZ2

Total number of chains: 2

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLAminus	2	7A55A

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism
CMGC	DYRK1A	DYR1A_HUMAN	7A55	2.2	Active	DFGin‑BLAminus	in-in	in-in	QZ2	Type1	136 - 481	0	X321	None	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens
CMGC	DYRK1A	DYR1A_HUMAN	7A55	2.2	Inactive	DFGin‑BLAminus	in-in	in-out	QZ2	Type1	134 - 481	0	X321	None	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens

Ligand: QZ2

Total number of chains: 0

Spatial label	Dihedral label	Number of Chains	Representative

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism